Successful Treatment of PD Peritonitis Due to Morganella morganii Resistant to Third-Generation Cephalosporins – A Case Report

2017 ◽  
Vol 37 (2) ◽  
pp. 241-242 ◽  
Author(s):  
Vaibhav Keskar ◽  
Mohan Biyani ◽  
Syed Obaid Amin ◽  
Greg Knoll
Keyword(s):  
Peritoneal Dialysis ◽  
Case Report ◽  
Antibiotic Therapy ◽  
Successful Treatment ◽  
Third Generation ◽  
Morganella Morganii ◽  
Oral Ciprofloxacin ◽  
Microbiologic Diagnosis ◽  
Third Generation Cephalosporins

Morganella morganii is a rare cause of peritonitis in patients on peritoneal dialysis (PD). Most of the reported cases have resorted to a switch to hemodialysis. We herein report a case of peritonitis due to M. morganii resistant to third-generation cephalosporins, which was treated successfully with intraperitoneal (IP) tobramycin followed by oral ciprofloxacin. Early microbiologic diagnosis is essential in the treatment of peritonitis from rare microorganisms such as Morganella morganii, and appropriate antibiotic therapy is the key to avoiding catheter loss and subsequent switch to hemodialysis.

Successful Treatment of Severe Complicated Cholangitis Using Regional Antibiotic Therapy (Case Report)

2016 ◽  
Vol 0 (1-2.30-31) ◽  
pp. 78
Author(s):  
V.I. Desiateryk ◽  
O.V. Kotov ◽  
O.V. Brovko ◽  
K.P. Alimov ◽  
O.A. Hul
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Successful Treatment

scholarly journals Oral Microbiota of the Snake Bothrops lanceolatus in Martinique

2018 ◽  
Vol 15 (10) ◽  
pp. 2122 ◽  
Author(s):  
Dabor Résière ◽  
Claude Olive ◽  
Hatem Kallel ◽  
André Cabié ◽  
Rémi Névière ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Generation Cephalosporin ◽  
Oral Microbiota ◽  
Third Generation ◽  
Beta Lactams ◽  
Morganella Morganii ◽  
Enterococcus Spp ◽  
Bacillus Spp ◽  
Amoxicillin Clavulanate ◽  
Third Generation Cephalosporins

In Martinique, Bothrops lanceolatus snakebite, although relatively uncommon (~30 cases/year), may result in serious complications such as systemic thrombosis and local infections. Infections have been hypothesized to be related to bacteria present in the snake’s oral cavity. In this investigation, we isolated, identified, and studied the susceptibility to beta-lactams of bacteria sampled from the oral cavity of twenty-six B. lanceolatus specimens collected from various areas in Martinique. Microbiota from B. lanceolatus oral cavity was polymicrobial. Isolated bacteria belonged to fifteen different taxa; the most frequent being Aeromonas hydrophyla (present in 50% of the samples), Morganella morganii, Klebsiella pneumoniae, Bacillus spp., and Enterococcus spp. Analysis of antibiotic susceptibility revealed that 66.7% of the isolated bacteria were resistant to amoxicillin/clavulanate. In contrast, the majority of isolated bacteria were susceptible to the third-generation cephalosporins (i.e., 73.3% with cefotaxime and 80.0% with ceftazidime). Microbiota from B. lanceolatus oral cavity is polymicrobial with bacteria mostly susceptible to third-generation cephalosporins but rarely to amoxicillin/clavulanate. In conclusion, our findings clearly support that first-line antibiotic therapy in the B. lanceolatus-bitten patients, when there is evidence of infection, should include a third-generation cephalosporin rather than amoxicillin/clavulanate.

Infections Due to Salmonella

2021 ◽  
Author(s):  
Marcia B Goldberg ◽  
Molly Paras
Keyword(s):  
Antibiotic Resistance ◽  
Antibiotic Therapy ◽  
Enteric Fever ◽  
Carrier State ◽  
Surgical Removal ◽  
Third Generation ◽  
Food Borne ◽  
Extraintestinal Disease ◽  
Immunocompromised Hosts ◽  
Third Generation Cephalosporins

Salmonella, which is acquired via ingestion, is classified as nontyphoidal or typhoidal disease. Typhoidal disease is caused by S typhi or S paratyphi, and nontyphoidal disease is caused by all other serovars. Salmonella causes a range of infectious syndromes that include gastroenteritis, bacteremia, endovascular infections, and enteric fever. For immunocompromised hosts or patients with extraintestinal disease, antibiotic therapy should be provided. Effective agents often include third-generation cephalosporins and fluoroquinolones, although rates of resistance of Salmonella isolates to many antibiotics are increasing. A carrier state exists whereby patients may shed bacteria despite being asymptomatic. To eradicate the carrier state, longer courses of antibiotics and, in rare instances, surgical removal of the reservoir, which is most commonly the gallbladder, may be required.  This review contains 2 figures, 4 tables, and 24 references. Key Words: Salmonella, typhoidal, non-typhoidal, enteric fever, endovascular infection, gastroenteritis, carrier, food-borne, antibiotic resistance

Odontogenic phlegmon of the mouth floor: a case report

2016 ◽  
Vol 6 (2) ◽  
pp. 0-0
Author(s):  
P. Bortnik ◽  
P. Wieczorek ◽  
P. Załęski ◽  
P. Kosierkiewicz ◽  
A. Siemiątkowski ◽  
...  
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Plastic Surgery ◽  
Successful Treatment ◽  
Surgical Intervention ◽  
University Hospital ◽  
Local Complication ◽  
Life Threatening ◽  
Ludwig’S Angina ◽  
The University

Odontogenic phlegmon of the mouth floor—Ludwig's angina (phlegmonae fundi cavi oris seu angina Ludovici)—is a rare, life-threatening, local complication in most cases of odontogenic inflammation. This study presents the case of a patient treated in the Department of Maxillofacial and Plastic Surgery of the University Hospital in Białystok due to phlegmon of the mouth floor resulting from odontogenic inflammation with a dynamic course. Quick diagnostics, surgical intervention as well as antibiotic therapy contributed to its efficient and successful treatment.

scholarly journals Successful treatment of acute renal failure secondary to complicated infective endocarditis by peritoneal dialysis: a case report

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Aisha M. Al-Osail ◽  
Ibrahim M. Al-Zahrani ◽  
Abdullah A. Al-Abdulwahab ◽  
Sarah M. Alhajri ◽  
Emad M. Al-Osail ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Peritoneal Dialysis ◽  
Case Report ◽  
Infective Endocarditis ◽  
Successful Treatment

scholarly journals Listeria monocytogenes Peritonitis in a Patient Receiving Continuous Ambulatory Peritoneal Dialysis: A Case Report and Review of the Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Ho-Kwan Sin ◽  
Au Cheuk ◽  
William Lee ◽  
Ka-Fai Yim ◽  
Clara Poon ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Case Report ◽  
Listeria Monocytogenes ◽  
Antibiotic Therapy ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Optimal Management ◽  
Review Of The Literature

Listeria monocytogenes is a rare cause of peritoneal dialysis-related peritonitis. Only a handful of cases have been reported, and the optimal management is still uncertain. We present a case of Listeria monocytogenes peritonitis and perform a review of the literature to elucidate optimal antibiotic therapy.

scholarly journals Antibacterial therapy in the treatment of ascites peritonitis in liver cirrhosis

2018 ◽  
Vol 16 (2) ◽  
pp. 49-56
Author(s):  
Sergey Ya Ivanusa ◽  
Igor Ev Onnitsev ◽  
Alexey V Khokhlov ◽  
Petr N Zubarev ◽  
Alexander V Yankovsky ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Antibiotic Therapy ◽  
Antibacterial Therapy ◽  
Antibacterial Effect ◽  
Decompensated Cirrhosis ◽  
Antibacterial Drug ◽  
Third Generation ◽  
Results Of Treatment ◽  
Main Component ◽  
Third Generation Cephalosporins

Ascites-peritonitis is a severe complication in patients with decompensated cirrhosis. The effectiveness of treatment of ascites of peritonitis depends largely on its early diagnosis. The main component of the treatment of ascites-peritonitis - a complex and targeted antibiotic therapy. Third-generation cephalosporins are recommended as empirical antibiotic therapy. The article presents the results of treatment of ascites peritonitis depending on the method of administration of antibacterial drug - cefbactam. The drug was administered in three ways: intravenous, endolymphatic and combined. The results of pharmacokinetics of the drug depending on the method of administration, as well as the results of the effectiveness of the antibacterial effect in the compared groups of patients. (For citation: Ivanusa SY, Onnitsev IE, Khokhlov AV, et al. Antibacterial therapy in the treatment of ascites peritonitis in liver cirrhosis. Reviews on Clinical Pharmacology and Drug Therapy. 2018;16(2):49-56. doi: 10.17816/RCF16249-56).

scholarly journals Piperacillin-tazobactam should be preferred to third-generation cephalosporins to treat wild-type inducible AmpC-producing Enterobacteriaceae in critically ill patients with hospital or ventilator-acquired pneumonia. A propensity score-matched analysis

2019 ◽  
Author(s):  
Cédric Carrié ◽  
Guillaume Bardonneau ◽  
Laurent Petit ◽  
Alexandre Ouattara ◽  
Didier Gruson ◽  
...  
Keyword(s):  
Propensity Score ◽  
Antibiotic Therapy ◽  
Pulmonary Infection ◽  
Therapeutic Failure ◽  
Third Generation ◽  
Pulmonary Infections ◽  
Wild Type ◽  
First Line ◽  
Emergence Of Resistance ◽  
Third Generation Cephalosporins

Abstract BACKGROUND The aim of this study was to compare the rate of therapeutic failure and emergence of resistance in critically ill patients treated by third-generation cephalosporins (3GCs) or piperacillin-tazobactam (PTZ) for wild-type AmpC-producing Enterobacteriaceae pulmonary infections. METHODS In a multicenter retrospective cohort study over a 4-year period, all patients treated for a pulmonary infection related to wild-type AmpC-producing Enterobacteriaceae who received documented antibiotic therapy with 3GCs or PTZ after less than 48 hours of empirical antibiotic therapy were eligible. The main outcome was the rate of therapeutic failure, defined by an impaired clinical response under treatment and/or a relapse of pulmonary infection related to the same pathogen. The secondary outcome was a secondary acquisition of derepressed cephalosporinase-producing Enterobacteriaceae. RESULTS Over the study period, 244 patients were included; 56 (23%) experienced therapeutic failure and 19 (8%) experienced secondary acquisition of resistance. In the non-adjusted cohort, the rate of therapeutic failure and emergence of resistance were significantly higher in the 3GCs group (32 vs. 18%, p = 0.011 and 13 vs. 5%, p = 0.035, respectively). In the propensity score-matched population, the 3GCs group was associated with higher rates of therapeutic failure (HR = 1.61 [1.27 – 2.07]). The secondary de-escalation to 3GCs after 48h of PTZ as a first-line antibiotic therapy was not associated with increased rate of emergence of resistance. CONCLUSION Our study confirms that third-generation cephalosporins should be avoided as first-line antibiotic therapy in wild-type AmpC-producing Enterobacteriaceae pulmonary infections.

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