scholarly journals Clinical Course Of Non-Specific Aortoartheritis (Disease Takayasu) (Casefrompractice)

Author(s):  
Tuxtayeva Mashxura Muxiddinovna ◽  

This article discusses the issues of early diagnosis of non-specific aortoarteritis are not generally accepted and therefore remain relevant. Takayasu syndrome (non-specific aortoarteritis) is an autoimmune inflammatory disease that affects the aorta and its branches, belongs to the group of systemic vasculitis, is characterized by the development of productive inflammation in the wall of large arteries leading to their obliteration, there is no pulsation due to frequent cases of loss of pulse in the upper extremities. The course of the disease is progressive with periodic exacerbations and deterioration of blood circulation in ischemic organs, as well as an unfavorable prognosis. Modern data on the etiology, pathogenesis, and clinical picture of Takayasu syndrome are presented. An important role in the diagnosis of non-specific aortoarteritis is played by computer and magnetic resonance imaging, as well as ultrasound examination of vessels that can detect typical signs of stenosis or aneurysm of the arteries. Treatment of the disease with the use of drugs aimed at suppressing the activity Of b cells of the immune system, as well as with the use of an IL-6 receptor inhibitor, is discussed. In order to attract the attention of General practitioners to a rare rheumatological problem – Takayasu aortoarteritis – the results of their own observations are presented. The clinical picture of the disease in a child is described.

Author(s):  
S.V. Idimesheva, E.G. Bazhenova, V.A. Vedernikov

А case of ultrasound diagnosis of the giant fetal cervical tumor in the third trimester of gestation is presented. The diagnosis of a cervical teratoma was supposed by ultrasound examination and magnetic resonance imaging. The tumor resection was successfully performed at 6 days of life. Histopathological diagnosis was mature teratoma.


2021 ◽  
pp. 135245852110196
Author(s):  
Rosa Cortese ◽  
Marco Battaglini ◽  
Francesca Parodi ◽  
Maria Laura Stromillo ◽  
Emilio Portaccio ◽  
...  

The mechanisms responsible for the favorable clinical course in multiple sclerosis (MS) remain unclear. In this longitudinal study, we assessed whether magnetic resonance imaging (MRI)-based changes in focal and diffuse brain damage are associated with a long-term favorable MS diseases course. We found that global brain and gray matter (GM) atrophy changes were milder in MS patients with long-standing disease (⩾30 years from onset) and favorable (no/minimal disability) clinical course than in sex-age-matched disable MS patients, independently of lesions accumulation. Data showed that different trajectories of volume changes, as reflected by mild GM atrophy, may characterize patients with long-term favorable evolution.


2021 ◽  
Vol 3 ◽  
pp. 67-69
Author(s):  
Shalini Agarwal ◽  
Jyoti Siwach ◽  
Ramneet Wadi ◽  
Nipun Gupta

We report a case of a 55-year-old male patient who presented with swelling over his right elbow of 5-year duration. An ultrasound examination revealed an echogenic mass within the olecranon bursa. On magnetic resonance imaging, the mass revealed the signal intensity of fat, and it was attached to the bursal lining by means of a pedicle. There was no restriction on diffusion-weighted images and no significant contrast enhancement. Excision was performed under local anesthesia. The excised specimen revealed mature fat cells on histopathology.


2021 ◽  
Vol 74 (7-8) ◽  
pp. 273-276
Author(s):  
Nazan Şimşek Erdem ◽  
Seden Demirci ◽  
Tuğba Özel ◽  
Khalida Mamadova ◽  
Kamil Karaali ◽  
...  

Vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been rapidly developed to prevent coronavirus disease 2019 (COVID-19) pandemic. There is increasing safety concerns regarding COVID-19 vaccines. We report a 78-year old woman who was presented with tetraparesis, paresthesias of bilateral upper extremities, and urinary retention of one-day duration. Three weeks before these symptoms, she was vaccinated with CoronaVAC vaccine (Sinovac Life Sciences, China). Spine magnetic resonance imaging showed longitudinally extensive transverse myelitis (TM) from the C1 to the T3 spinal cord segment. An extensive diagnostic workup was performed to exclude other possible causes of TM. We suggest that longitudinally extensive TM may be associated with COVID-19 vaccination in this case. To the best of our knowledge, this is the first report of longitudinally extensive TM developing after CoronaVac vaccination. Clinicians should be aware of neurological symptoms after vaccination of COVID-19.


2021 ◽  
pp. 68-72
Author(s):  
I. N. Sonkin ◽  
L. I. Syromyatnikova ◽  
E. Kh. Alieva ◽  
S. A. Mehryakov

Goal. Consider the management of patients with effort thrombosis (Paget-Schretter syndrome).The article presents the modern vision of the problem of effort thrombosis. This review is aimed at describing the epidemiology, pathophysiology, diagnosis and treatment of patients with Paget-Schretter syndrome. SPS occurs spontaneously, as a rule, in young, healthy and active patients aged 20-30 years after strenuous physical activity. The ratio of men and women is 2:1, recently there has been a growing trend among women. The main complaints of patients with SPS include swelling of the affected limb, discomfort when moving the affected arm, pain and heaviness when trying to raise the arm up. When examining these patients, attention is paid to hyperemia of the skin or their cyanotic nature, pasty limbs, as well as an enhanced venous pattern on the shoulder, the so-called Arshel sign. The diagnosis is based on the data of anamnesis, physical examination, the “gold standard of diagnostics” – ultrasound examination of veins, the sensitivity and specificity of which is 70-100%. The first step in the diagnosis can be the evaluation of the D-dimer, with its negative values, the SPSH is rejected. With an obvious clinic and controversial results of serial ultrasound examinations, other imaging methods are used, such as computed contrast tomography, magnetic resonance imaging, the diagnostic value of which is especially significant in occlusive venous thrombosis.SPS differs not only from DVT of the lower extremities, but also from secondary DVT of the upper extremities, which determines the peculiarities of management of this category of patients, including surgical treatment aimed at preventing subclavian vein compression in the future. The article summarizes the experience in the management of patients with blood thrombosis.


Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5072
Author(s):  
Xiaodong Li ◽  
Yanhong Sun ◽  
Lina Ma ◽  
Guifeng Liu ◽  
Zhenxin Wang

The advancements of magnetic resonance imaging contrast agents (MRCAs) are continuously driven by the critical needs for early detection and diagnosis of diseases, especially for cancer, because MRCAs improve diagnostic accuracy significantly. Although hydrophilic gadolinium (III) (Gd3+) complex-based MRCAs have achieved great success in clinical practice, the Gd3+-complexes have several inherent drawbacks including Gd3+ leakage and short blood circulation time, resulting in the potential long-term toxicity and narrow imaging time window, respectively. Nanotechnology offers the possibility for the development of nontoxic MRCAs with an enhanced sensitivity and advanced functionalities, such as magnetic resonance imaging (MRI)-guided synergistic therapy. Herein, we provide an overview of recent successes in the development of renal clearable MRCAs, especially nanodots (NDs, also known as ultrasmall nanoparticles (NPs)) by unique advantages such as high relaxivity, long blood circulation time, good biosafety, and multiple functionalities. It is hoped that this review can provide relatively comprehensive information on the construction of novel MRCAs with promising clinical translation.


2013 ◽  
Vol 6 ◽  
pp. CCRep.S13309
Author(s):  
Hieu Tran ◽  
Anthony Allworth ◽  
Cameron Bennett

We report a rare cause of encephalitis that is not often described in the adult clinical setting. Our case was a 16-year-old female who presented with a clinical picture of viral encephalitis; however, magnetic resonance imaging showed a demyelinating lesion of the left frontal lobe. In this age group, differential diagnoses of acute demyelination encephalomyelitis and multiple sclerosis were entertained. Further investigations demonstrated positive Mycoplasma pneumoniae serology. As a result, a diagnosis of Mycoplasma pneumoniae-associated encephalitis was made based on a process of exclusion.


2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Megumi Kaneko ◽  
Yasuhiko Ebina ◽  
Nanae Shinozaki ◽  
Yui Yamasaki ◽  
Masashi Deguchi ◽  
...  

Abstract Massive subchorionic thrombosis (MST) is defined as a massive thrombosis under the chorionic plate, and is responsible for obstetric complications. We encountered two cases of MST. Placental abruption was misdiagnosed by ultrasound examination in Case 1, and a cesarean section was performed at 33 weeks of gestation. Magnetic resonance imaging (MRI) at 21 weeks of gestation suggested MST in Case 2. A cesarean section was performed at 26 weeks’ gestation because of pregnancy-induced hypertension, fetal growth restriction and non-reassuring fetal status.


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