scholarly journals α-((4-Cyanobenzoyl)oxy)-ω-methyl poly(ethylene glycol): a new stabilizer for silver nanoparticles

2017 ◽  
Vol 8 ◽  
pp. 627-635 ◽  
Author(s):  
Jana Lutze ◽  
Miguel A Bañares ◽  
Marcos Pita ◽  
Andrea Haase ◽  
Andreas Luch ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Ethylene Glycol ◽  
Metal Nanoparticles ◽  
Ph Value ◽  
Aqueous Media ◽  
Poly Ethylene Glycol ◽  
H Nmr ◽  
Anchor Group ◽  
Poly Ethylene ◽  
Cyano Groups

The article describes the synthesis and properties of α-((4-cyanobenzoyl)oxy)-ω-methyl poly(ethylene glycol), the first poly(ethylene glycol) stabilizer for metal nanoparticles that is based on a cyano rather than a thiol or thiolate anchor group. The silver particles used to evaluate the effectiveness of the new stabilizer typically have a bimodal size distribution with hydrodynamic diameters of ca. 13 and ca. 79 nm. Polymer stability was evaluated as a function of the pH value both for the free stabilizer and for the polymers bound to the surface of the silver nanoparticles using 1H NMR spectroscopy and zeta potential measurements. The polymer shows a high stability between pH 3 and 9. At pH 12 and higher the polymer coating is degraded over time suggesting that α-((4-cyanobenzoyl)oxy)-ω-methyl poly(ethylene glycol) is a good stabilizer for metal nanoparticles in aqueous media unless very high pH conditions are present in the system. The study thus demonstrates that cyano groups can be viable alternatives to the more conventional thiol/thiolate anchors.

Copolymer Nanoparticles Prepared by Self-Assembly of Poly(ethylene glycol) and Poly-γ-Glutamic Acid and its Characteristics

2013 ◽  
Vol 662 ◽  
pp. 136-139
Author(s):  
Ge Yang ◽  
Ke Shuai Lu ◽  
Xue Yan Su
Keyword(s):  
Ethylene Glycol ◽  
Glutamic Acid ◽  
Size Distribution ◽  
Self Assembly ◽  
Aqueous Media ◽  
Poly Ethylene Glycol ◽  
Polyelectrolyte Complexes ◽  
Self Assembling ◽  
Transmission Electron ◽  
Poly Ethylene

The paper describes the preparation and characterization of novel biodegradable nanoparticles based on self-assembly of poly-gamma-glutamic acid (γ-PGA) and poly(ethylene glycol) (PEG). The nanosystems were stable in aqueous media at low pH conditions. Solubility of the systems was determined by turbidity measurements. The particle size and the size distribution of the polyelectrolyte complexes were identified by dynamic lightscattering and transmission electron microscopy.It was found that the size and size distribution of the nanosystems depends on the concentrations of γ-PGA and PEG solutions and their ratio as well as on the pH of the mixture and the order of addition. The diameter of individual particles was in the range of 30–270 nm. measured by TEM, and the average hydrodynamic diameters were between 130 and 300 nm. These biodegradable, self-assembling stable nanocomplexes might be useful for several biomedical applications.

Preparation and Characterization of pH Responsive Complex Micelles with Dynamic Boronate Cross-Linking

2019 ◽  
Vol 944 ◽  
pp. 557-564
Author(s):  
Jia Ming Xu ◽  
Dan Yue Wang ◽  
Han Tong ◽  
Xiao Ze Jiang ◽  
Mei Fang Zhu
Keyword(s):  
Ethylene Glycol ◽  
Phenylboronic Acid ◽  
Proton Nuclear Magnetic Resonance ◽  
Cross Linking ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Boronate Ester ◽  
H Nmr ◽  
Poly Ethylene ◽  
Complex Micelles

Two kinds of diblock copolymers containing glucose and phenylboronic acid moieties, respectively, poly (ethylene glycol)-b-poly (gluconamidoethyl methacrylate) (PEG-b-PGAMA) and poly (ethylene glycol)-b-poly (2-aminoethyl methacrylate-co-3-nitrophenyboronic acid methacrylate) (PEG-b-P(AMA-co-NPBMA)) were synthesized via atom transfer radical polymerization (ATRP) and post polymerization modification (PPM). Well-defined structure and narrow molecular weight distribution of the polymers were confirmed by proton Nuclear Magnetic Resonance (1H NMR) and Gel Permeation Chromatography (GPC). Based on the cross-linking between the diol groups of the glycopolymer and phenylboronic acid under physiological pH (7.4), complex micelles composed of PEG outer shell and boronate ester cross-linking core with a hydrodynamic diameter around 20nm were formed. Morphology, size and assembly behavior of the complex micelles were investigated by 1H NMR, transmission electron microscopy (TEM) and dynamic light scattering (DLS). The results showed the formation/cleavage of boronate ester linkage is reversible upon the variation of solution pH, the complex micelles displayed pH sentiveties of assembling/disassembling behavior. Above pH 7.4, stable spherical micelles can be formed, whereas pH less than 5.5, the micelles dissociated into unimers. Therefore, such pH-responsive micelles based on dynamic complexation of phenyl boronate bonds are expected to be applied to pH-responsive nanodrug carriers

Ag@SiO2-entrapped hydrogel microarray: a new platform for a metal-enhanced fluorescence-based protein assay

The Analyst ◽  
2015 ◽  
Vol 140 (10) ◽  
pp. 3375-3383 ◽  
Author(s):  
Eunji Jang ◽  
Minsu Kim ◽  
Won-Gun Koh
Keyword(s):  
Silver Nanoparticles ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Enhanced Fluorescence ◽  
Metal Enhanced Fluorescence ◽  
Protein Assay ◽  
Poly Ethylene

We developed a novel silver-based metal-enhanced fluorescence (MEF) biosensing platform that consisted of poly(ethylene glycol)(PEG) hydrogel microstructures entrapping silica-coated silver nanoparticles (Ag@SiO2).

The Swelling and Transition Behavior of Thermo-Responsive Poly(2-(2-Methoxyethoxy) Ethoxyethyl Methacrylate-co-Poly(Ethylene Glycol) Methyl Ether Methacrylate) Thin Films

2021 ◽  
Vol 873 ◽  
pp. 59-64
Author(s):  
Yang Yi Chen ◽  
Wen Jing Wen ◽  
Zhi Qin Su ◽  
Qi Huan ◽  
Chu Yang Zhang
Keyword(s):  
Thin Films ◽  
Ethylene Glycol ◽  
Methyl Ether ◽  
Random Copolymer ◽  
Molar Ratio ◽  
Poly Ethylene Glycol ◽  
H Nmr ◽  
Poly Ethylene ◽  
Copolymer Poly ◽  
Glycol Methyl Ether

Thermo-responsive random copolymer poly (2-(2-methoxyethoxy) ethoxyethyl methacrylate-co-poly (ethylene glycol) methyl ether methacrylate), abbreviated as P(MEO2MA-co-OEGMA300) was synthesized by 2-(2-methoxyethoxy) ethoxyethyl methacrylate (MEO2MA) and poly (ethylene glycol) methyl ether methacrylate (OEGMA300) with a molar ratio of 1:1 via atom transfer radical polymerization (ATRP). The structure of P(MEO2MA-co-OEGMA300) was confirmed by 1H NMR and GPC. The transition behaviors of P(MEO2MA-co-OEGMA300) in aqueous solution were investigated by UV-Vis and DLS. While the transition behaviors of P(MEO2MA-co-OEGMA300) thin films were probed by white light interferometry. Compared to the P(MEO2MA-co-OEGMA300) in solution, it shows a much broader transition region, which is a promising candidate for the slow release of drug in the field of medicine.

Preparation of Chlropyrofos Loaded Silver Nanoparticles Coated with Poly(ethylene glycol) and Chitosan and Evaluation of Termiticide Activity

2018 ◽  
Vol 3 (4) ◽  
pp. 87-91
Author(s):  
Vahid Derakhsh Ahmadi ◽  
Zahra Rafiei- Karahroudi ◽  
Shila Goldasteh ◽  
Elham Sanatgar ◽  
Babak Heidary Alizadeh
Keyword(s):  
Silver Nanoparticles ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Stabilization of Silver Nanoparticles by Polyelectrolytes and Poly(ethylene glycol)

2007 ◽  
Vol 28 (7) ◽  
pp. 848-855 ◽  
Author(s):  
Darya Radziuk ◽  
Andre Skirtach ◽  
Gleb Sukhorukov ◽  
Dmitry Shchukin ◽  
Helmuth Möhwald
Keyword(s):  
Silver Nanoparticles ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals A non-sacrificial method for the quantification of poly(ethylene glycol) grafting density on gold nanoparticles for applications in nanomedicine

2019 ◽  
Vol 10 (7) ◽  
pp. 2067-2074 ◽  
Author(s):  
Jun Lu ◽  
Yao Xue ◽  
Rui Shi ◽  
Jing Kang ◽  
Chao-Yang Zhao ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Splitting Algorithm ◽  
H Nmr ◽  
Grafting Density ◽  
Poly Ethylene

A multi-Lorentzian-splitting algorithm is used to distinguish the 1H NMR signal of free PEG from that of grafted PEG, therefore allowing monitoring of the grafting process in situ.

Simultaneously Synthesis and Encapsulation of Metallic Nanoparticles Using Linear–Dendritic Block Copolymers of Poly(ethylene glycol)-Poly(citric acid)

2011 ◽  
Vol 478 ◽  
pp. 7-12 ◽  
Author(s):  
Ashkan Tavakoli Naeini ◽  
Manouchehr Vossoughi ◽  
Mohsen Adeli
Keyword(s):  
Aqueous Solution ◽  
Silver Nanoparticles ◽  
Citric Acid ◽  
Ethylene Glycol ◽  
Aqueous Solutions ◽  
Metallic Nanoparticles ◽  
Loading Capacity ◽  
Poly Ethylene Glycol ◽  
Gold And Silver Nanoparticles ◽  
Poly Ethylene

Linear-dendritic triblock copolymers of linear poly(ethylene glycol) and hyperbranched poly(citric acid) (PCA-PEG-PCA) were used as the reducing and capping agents to encapsulate gold and silver nanoparticles (AuNPs and AgNPs). PCA-PEG-PCA copolymers in four different molecular weights were synthesized using 2, 5, 10 and 20 citric acid/PEG molar ratios and were called A1, A2, A3 and A4, respectively. Nanoparticles were encapsulated simultaneously during the preparation process. AuNPs were simply synthesized and encapsulated by addition a boiling aqueous solution of HAuCl4 to aqueous solutions of A1, A2, A3 and A4. In the case of silver, an aqueous solution of AgNO3 was reduced using NaBH4 and AgNPs were encapsulated simultaneously by adding aqueous solutions of different PCA-PEG-PCA to protect the fabricated silver nanoparticles from aggregation. Encapsulated AuNPs and AgNPs were stable in water for several months and agglomeration did not occur. The synthesized silver and gold nanoparticles have been encapsulated within PCA-PEG-PCA macromolecules and have been studied using Transmission Electron Microscopy (TEM) and UV/Vis absorption spectroscopy. Studies reveal that there was a reverse relation between the size of synthesized AuNPs/AgNPs and the size of citric acid parts of PCA-PEG-PCA copolymers. For example, the prepared gold and silver nanoparticles by A3 copolymer are of an average size of 8 nm and 16 nm respectively. Finally, the loading capacity of A1, A2, A3 and A4 and the size of synthesized AuNPs and AgNPs were investigated using UV/Vis data and the corresponding calibration curve. It was found that the loading capacity of copolymers depends directly on the concentration of copolymers and their molecular weight.

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