scholarly journals Prevention of Viral Effect and Enhancement of Immune System with the help of Herbal Plants and Himalayan Crude Drugs in SAR-COV-2 Patient; A Review.

Author(s):  
Rishiram BARAL
2021 ◽  
pp. 245-254
Author(s):  
Mani Divya ◽  
Sekar Vijayakumar

2021 ◽  
Vol 23 (08) ◽  
pp. 92-106
Author(s):  
◽  
Payal Mittal ◽  

It is an evident from ancient times that herbs and medicinal plants have the potential to cure a variety of diseases. Some plants boosts our immunity and make our immune system more powerful to fight againt various diseases. The medicinal effects shown by the plants are due to active principle compound present in them and they work in the same manner as the conventioal drugs. Indian herbs and medicinal plants show miraculous effects against wide variety of diseases and disorders in humansand can be better called as “elixers of life”. Currently, the interest is increasing with high pace in the use of active constituents of medicinal plants as modulator or enhancer of complex immune system. From the literature of various studies carried out in the research area , it is culminated that many of the chemicals in the form of alkaloids, flavanoids, anti-oxidants, tannins, terpenes, and glycoside products are responsible to empower the immunmodulator effect. Keeping in mind , the appreciating potential of active constituents of medicinal plants and their derived drugs, present review is an attemptto globally popularize the herbal plants with Immunomodulator Activity.


2021 ◽  
Vol 7 (2) ◽  
pp. 124-133
Author(s):  
Jaydip Jikadara ◽  
◽  
Samresh Pal Roy ◽  

The present review focuses on the overview of the immune system regarding its protection of the human body against COVID-19 virus; illustrates the immunity boosting activity of herbal plants against SARS-CoV-2 infection. This work also provides information regarding virus structure information, immunopathogensis of virus with human body and role of Ayurveda in coronavirus disease. A number of herbal plants based active principles have been isolated and extracted with potential immunostimulant and immunosuppressant activity that can explain their beneficial use in traditional medicine and form the further research base for the future studies. The goal of this review is to foreground the immunity boosting activity of different herbal plants and its beneficial use in COVID-19 disease. Many plants and their phytochemicals, responsible for immunomodulation mechanism in SARS-CoV-2 infection have been explained. This review shall hopefully encourage researchers to undertake further work on herbal or medicinal plants with potential immunity boosting activity in COVID-19 disease.


2020 ◽  
Vol 9 (4) ◽  
pp. 1538-1546

The worldwide epidemic of SARS-CoV-2 has created a panic situation in human beings. Covid-19 viruses spread infections into the specific human cells through cell-surface receptor ACE2 and start viral replication speedily inside the human body. The action of antibodies can reduce the entry of the virus into the cell by binding with the spike head and prevent to connect with ACE2 receptor. Many types of research are going to find the exact vaccine to control the spread of this virus. But still, now there is no vaccine and specific medicine invented still now, which is a big headache across the world. At this pandemic period, boosting of the immune system is the best way to fight against this virus. From ancient times, Ayurved is known as the best immune booster for animals and mammals. The herbal plants, such as Nyctanthes arbor-tristis L. And Withania somnifera has excellent immunomodulatory, anti-inflammatory, antitumor, inhibition of oxidants, carcinopreventive properties with important chemicals like Withaferins, different alkaloids, steroids, amino acids. This review is based on a brief discussion of the pharmacological behaviors, active ingredients, and potential therapeutic applications of these medicinal plants.


2021 ◽  
Vol 10 (1) ◽  
pp. 25-53
Author(s):  
Winda Trisna Wulandari ◽  
Gina Nur Fitria Mulyana Putri ◽  
Hisni Nurul Fajri ◽  
Indah Alvina Damayanti ◽  
Silvia Rahmawati ◽  
...  

COVID-19 (Coronavirus Disease-2019) is an infectious disease caused by the acute respiratory syndrome SARS-CoV-2. Currently, the COVID-19 disease outbreak is experienced by various countries around the world, including Indonesia. In overcoming it, there are several ways of deterrence that can be done, such as by increasing the body's immunity. During the COVID-19 pandemic, maintaining immunity is something that needs to be considered. In addition to vitamins, herbal plants that have the potential as immunomodulators can also be consumed. Therefore, through efforts to improve theimmune system, this review aims to obtain plants that have the potential as immunomodulators to enhance the immune system during the COVID-19 pandemic. The research method in the review used journals available online at Google Scholar with Sinta or Garuda accredited journals. The main focus of this review is herbal plants that have a role as an immunomodulator that can improve the body's immune system. The journals used are journals published in 2011-2021 with inclusion criteria, namely using Indonesian or English about plants that have the potential as immunomodulators, then the journalsobtained are analyzed. The results obtained were 30 types of plants that have potential as immune system enhancers including Dayak Onion Tubers, Papaya Leaves, Kecombrang Fruits, Pineapple Fruits, Kesambi, Soursop Leaves, Purslane, Garlic, Dates, Celery Leaves, Andaliman, Mahkota Dewa Fruit. , Moringa, Meniran, Noni Fruit, Gotu Kola, Sambiloto, Kiseureuh, Javanese Chili, Tempuyung Leaves, Basil Leaves, Ceplukan, Seaweed, Neem Leaves, Red Betel Leaf, Salam Leaves, Guava, Turmeric, Lime and Red Ginger Rhizome with compounds that act as flavonoids, alkaloids, saponins, triterpenoids,xeronin, tannins, quersentin, -tocopherol, lycopene, catechins, diterpenoids, deoxyandrographolide, andrographolide, epicatechin isothiocyanate and curcumin. Keywords: COVID-19, Potency of Immumodulator Plants, Flavonoids


Author(s):  
Gyanendra Mohapatra ◽  
Biswa Mohan Sahoo ◽  
Bimalendu Chowdhury ◽  
J. Sruti ◽  
Rabi Narayan Rana ◽  
...  

: The immune system involves both active and passive immunization. The antibodies are devloped against the antigens during active immunization and are permanently stored. But, in case of passive immunization, the antibodies are exposed to the same antigens in every person who are already infected. In order to enhance the immune systems i.e. innate and adaptive immune responses, herbal plants are used as immune booster. Some of the herbal plants have been proved clinically to enhance the immunity that include Morniga oleifera (Drumstick), Azadirachta indica (Neem), Ocimum sanctum (Tulsi), Withania somnifera (Aswagandha), Zingiber officinale (Ginger), Allium sativum (Garlic), Curcuma longa (Turmeric), Emblica officinalis (Amla) etc. Compared to synthetic drugs, the herbal drugs have fewer or less side effects and stimulate the immune system to defend against various foreign pathogens. Even though, herbal medicines are usually considered as safe and effective therapy, but it is clinically proved that if a drug is effective, it would have some side effects. But, sometimes the antioxidant property of herbal medicines is helpful to reduce the toxicities produced by any toxic substances or any drugs. This review aims to encourage the study of various herbal constituents and their role in the treatment of different types of viral infections.


2021 ◽  
Vol 23 (07) ◽  
pp. 1460-1474
Author(s):  
◽  
Payal Mittal ◽  

It is an evident from ancient times that herbs and medicinal plants have the potential to cure a variety of diseases. Some plants boosts our immunity and make our immune system more powerful to fight againt various diseases. The medicinal effects shown by the plants are due to active principle compound present in them and they work in the same manner as the conventioal drugs. Indian herbs and medicinal plants show miraculous effects against wide variety of diseases and disorders in humansand can be better called as “elixers of life”. Currently, the interest is increasing with high pace in the use of active constituents of medicinal plants as modulator or enhancer of complex immune system. From the literature of various studies carried out in the research area , it is culminated that many of the chemicals in the form of alkaloids, flavanoids, anti-oxidants, tannins, terpenes, and glycoside products are responsible to empowerb the immunmodulator effect. Keeping in mind , the appreciating potential of active constituents of medicinal plants and their derived drugs, present review is an attemptto globally popularize the herbal plants with Immunomodulator Activity.


2014 ◽  
Vol 222 (3) ◽  
pp. 148-153 ◽  
Author(s):  
Sabine Vits ◽  
Manfred Schedlowski

Associative learning processes are one of the major neuropsychological mechanisms steering the placebo response in different physiological systems and end organ functions. Learned placebo effects on immune functions are based on the bidirectional communication between the central nervous system (CNS) and the peripheral immune system. Based on this “hardware,” experimental evidence in animals and humans showed that humoral and cellular immune functions can be affected by behavioral conditioning processes. We will first highlight and summarize data documenting the variety of experimental approaches conditioning protocols employed, affecting different immunological functions by associative learning. Taking a well-established paradigm employing a conditioned taste aversion model in rats with the immunosuppressive drug cyclosporine A (CsA) as an unconditioned stimulus (US) as an example, we will then summarize the efferent and afferent communication pathways as well as central processes activated during a learned immunosuppression. In addition, the potential clinical relevance of learned placebo effects on the outcome of immune-related diseases has been demonstrated in a number of different clinical conditions in rodents. More importantly, the learned immunosuppression is not restricted to experimental animals but can be also induced in humans. These data so far show that (i) behavioral conditioned immunosuppression is not limited to a single event but can be reproduced over time, (ii) immunosuppression cannot be induced by mere expectation, (iii) psychological and biological variables can be identified as predictors for this learned immunosuppression. Together with experimental approaches employing a placebo-controlled dose reduction these data provide a basis for new therapeutic approaches to the treatment of diseases where a suppression of immune functions is required via modulation of nervous system-immune system communication by learned placebo effects.


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