Phẫu thuật ung thư khoang miệng có tạo hình khuyết hổng bằng vạt dưới cằm

Journal of Clinical Medicine- Hue Central Hospital ◽

10.38103/jcmhch.2021.74.18 ◽

2021 ◽

Author(s):

Xuan Hung Nguyen

Keyword(s):

Survival Rate ◽

Oral Cancer ◽

Oral Cavity ◽

Cancer Surgery ◽

High Survival ◽

High Survival Rate ◽

Submental Flap ◽

A Prospective Study ◽

Oncology Center ◽

Cavity Function

TÓM TẮT Đặt vấn đề: Ung thư khoang miệng chiếm tỷ lệ 30% ung thư đầu cổ và 2.0% trong ung thư nói chung. Phẫu thuật phải đảm bảo cắt rộng u với diện cắt an toàn để hạn chế tái phát, nhưng thường để lại khuyết hổng khá lớn. Vạt dưới cằm được sử dụng rộng rãi trong tạo hình khuyết hổng vùng khoang miệng, có đặc điểm: tỷ lệ sống cao, linh hoạt. Nghiên cứu này nhằm đánh giá hiệu quả của vạt dưới cằm trong tạo hình khuyết hổng sau cắt ung thư khoang miệng tại khoa Phẫu Thuật - Trung tâm Ung Bướu - Bệnh viện Trung Ương Huế từ tháng 4/2020 - 8/2021. Đối tượng và phương pháp nghiên cứu: Đây là nghiên cứu tiến cứu can thiệp lâm sàng không nhóm chứng trên 8 trường hợp sử dụng vạt dưới cằm trong tạo hình khuyết hổng sau cắt ung thư khoang miêng. Kết quả: Kích thước vạt trung bình là 28 cm2 (4 x 7 cm), tái tao khuyết hổng vùng lưỡi 3 trường hợp, lưỡi sàn miệng 4 trường hợp, niêm mạc má và góc hậu hàm 1 trường hợp. Bệnh nhân được ăn qua đường miệng sau 8 ngày, xuất viện sau 12 ngày. Biến chứng: Rò miệng - cổ 2 trường hợp, hoại tử 1 phần vạt: 1 trường hợp. Sau 1 tháng, các vạt lành tốt, chức năng khoang miệng ảnh hưởng ít (chức năng nhai nuốt và phát âm ảnh hưởng ít). Sau 6 tháng, ghi nhận 7/8 trường hợp không tái phát tại chỗ, các vạt lành tốt, chức năng khoang miệng bình thường, 1 trường hợp tái phát tại chỗ. Kết luận: Vạt dưới cằm có tỷ lệ sống cao hỗ trợ lấp khuyết hổng vùng khoang miệng. ABSTRACT ORAL CANCER SURGERY WITH RECONSTRUCTION DEFECTS BY SUBMENTAL FLAP Introduction: Globally, oral cancer accounts for 30% of head and neck cancers and 2.0% of all cancer. The surgery must remove the tumor with safe marginal resection to limit recurrence; however, it causes large defects. The submental flap is gaining popularity as a technique for reconstructing oral defects, with advantages: high survival rate and flexibility. This study aimsto evaluate the efficacy of the submental flap in reconstructive defects after oral cancer surgery at the Department of Oncology Surgery - Oncology Center of Hue Central Hospital from April 2020 to August 2021. Methods: A prospective study was conducted on 8 patients who had defects reconstructed by a submental flap after oral cancer surgery. Results: The average dimension of the submental flap was 28 cm2 (4 x 7 cm). The reconstructed sites included: tongue (3 cases), floor of mouth (4 cases), buccal mucosa (1 case). Patients had oral feeds after 8 days, discharged after 12 days. Complications: Oro - cutaneous fistula (2 cases), partial necrosis (1 case). After one month, the flaps were survival, and the oral cavity function had reduced (swallowing and speech function were quite limited). After six months, 7/8 cases had no locoregional recurrence; the flap was good, and the oral cavity function was normal. One case had local recurrence. Conclusions: Submental flap is a valid option for reconstructing intra - oral soft tissue with a high survival rate. Keywords: Oral cancer, submental flap.

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High survival rate in advanced-stage B-cell lymphomas and leukemias without CNS involvement with a short intensive polychemotherapy: results from the French Pediatric Oncology Society of a randomized trial of 216 children.

Journal of Clinical Oncology ◽

10.1200/jco.1991.9.1.123 ◽

1991 ◽

Vol 9 (1) ◽

pp. 123-132 ◽

Cited By ~ 203

Author(s):

C Patte ◽

T Philip ◽

C Rodary ◽

J M Zucker ◽

H Behrendt ◽

...

Keyword(s):

Survival Rate ◽

B Cell ◽

Pediatric Oncology ◽

Stage Iv ◽

High Dose ◽

High Survival ◽

Advanced Stage ◽

High Survival Rate ◽

Cns Involvement

From April 1984 to December 1987, the French Pediatric Oncology Society (SFOP) organized a randomized trial for advanced-stage B-cell lymphoma without CNS involvement to study the possibility of reducing the length of treatment to 4 months. After receiving the same three intensive six-drug induction courses based on high-dose fractionated cyclophosphamide, high-dose methotrexate (HD MTX), and cytarabine in continuous infusion, patients were evaluated for remission. Those who achieved complete remission (CR) were randomized between a long arm (five additional courses with two additional drugs; 16 weeks of treatment) and a short arm (two additional courses; 5 weeks). For patients in partial remission (PR), intensification of treatment was indicated. Two hundred sixteen patients were registered: 15 stage II nasopharyngeal and extensive facial tumors, 167 stage III, and 34 stage IV, 20 of the latter having more than 25% blast cells in bone marrow. The primary sites of involvement were abdomen in 172, head and neck in 30, thorax in two, and other sites in 12. One hundred sixty-seven patients are alive in first CR with a minimum follow-up of 18 months; four are lost to follow-up. Eight patients died from initial treatment failure, 14 died from toxicity or deaths unrelated to tumor or treatment, and 27 relapsed. The event-free survival (EFS), with a median follow-up of 38 months, is 78% (SE 3) for all the patients, 73% (SE 11) for the stage II patients, 80% (SE 3) for the stage III patients, and 68% (SE 8) for the stage IV and acute lymphoblastic leukemia (ALL) patients. One hundred sixty-six patients were randomized: 82 in the short arm and 84 in the long arm. EFS is, respectively, 89% and 87%. Statistical analysis confirms equivalence of both treatment arms with regard to EFS. Moreover, morbidity was lower in the short arm. This study confirms the high survival rate obtained in the previous LMB 0281 study without radiotherapy or debulking surgery and demonstrates the effectiveness of short treatment.

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High survival rate of a critically endangered species, the Azores Bullfinch Pyrrhula murina, as a contribution to population recovery

Journal of Ornithology ◽

10.1007/s10336-010-0501-4 ◽

2010 ◽

Vol 151 (3) ◽

pp. 627-636 ◽

Cited By ~ 9

Author(s):

David Monticelli ◽

Ricardo Ceia ◽

Ruben Heleno ◽

Hugo Laborda ◽

Sergio Timóteo ◽

...

Keyword(s):

Survival Rate ◽

Endangered Species ◽

Critically Endangered ◽

High Survival ◽

Population Recovery ◽

High Survival Rate ◽

Critically Endangered Species

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Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate

HPB ◽

10.1111/j.1477-2574.2011.00370.x ◽

2011 ◽

Vol 13 (11) ◽

pp. 774-782 ◽

Cited By ~ 48

Author(s):

Andreas Andreou ◽

Antoine Brouquet ◽

Eddie K. Abdalla ◽

Thomas A. Aloia ◽

Steven A. Curley ◽

...

Keyword(s):

Survival Rate ◽

Liver Metastases ◽

Colorectal Liver Metastases ◽

Repeat Hepatectomy ◽

High Survival ◽

High Survival Rate

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Revegetation of Rock Slopes with Different Substrates in an Abandoned Quarry in Jinju, Korea

Journal of Geography and Geology ◽

10.5539/jgg.v8n3p26 ◽

2016 ◽

Vol 8 (3) ◽

pp. 26

Author(s):

Ma Hoseop ◽

Ettagbor Hans Enukwa ◽

Kang Wonseok ◽

Kim Choonsig

Keyword(s):

Growth Rate ◽

Survival Rate ◽

Festuca Arundinacea ◽

High Survival ◽

Rock Slopes ◽

High Survival Rate ◽

Feasible Method ◽

Leaf Mold ◽

Dianthus Barbatus ◽

Target Plant

The purpose of this research was to investigate the use of drilled slanted holes filled with different substrates in the revegetation of rock slopes. Slanted holes were drilled on rock slopes using pneumatic drillers in an abandoned limestone quarry area. These holes were filled with twelve different substrates, treated with Trichoderma harzianum. One climbing plant of Ivy (Hedera rhombea), a native woody plant (Lespedeza cyrtobotrya), three native herbaceous plants (Dianthus barbatus, Siberian chrysanthemum and Aster koraiensis) and one exotic grass plant (Festuca arundinacea) were planted in each of the soils. Six months after planting, only Ivy, Festuca arundinacea, Lespedeza cyrtobotrya and Dianthus barbatus were still observed growing on the soils, while the other plant species had already died in all the 12 soil treatments. Leaf mold soil + 50% Trichoderma harzianum provide the best conditions for revegetation of Festuca arundinacea, as this plant had its highest mean height, high survival rate, with impressive growth rate on this soil. Lespedeza cyrtobotrya also had its most favorable growth on Leaf mold soil + 50% T. harzianum. Mixed soil + 100% T. harzianum provide the best conditions for revegetation of Ivy. Leaf mold soil + 100% T. harzianum provide the best condition for revegetation of Dianthus barbatus as it had its highest mean height, highest growth rate and high survival rate on this soil. Siberian chrysanthemum and Aster koraiensis had the worse results as all of the plants died within a short period of time after planting. Ivy had the highest mean height, followed by Festuca arundinacea. The planted Ivy and Festuca arundinacea now form the vegetation of the research site which together with the substrate is now providing habitat to some wildlife like some species of centipedes, earthworms, insects and wild plants. Less than one year after planting, F. arundinacea already produced flowers and seeds which would further increase the plant population after dispersal and germination. Drilling slanted holes on rock slopes is therefore a feasible method to be used for revegetation and restoration of degraded quarries.The revegetation of steep rock slopes of quarries is a very challenging activity. However, the method of drilling slanted holes on rock slopes is a feasible method to be used for restoration of degraded quarries. These holes could serve in soil deposition and water retention that will further enhance plant growth.Methods of improving seed germination as well as enhancing growth of plants are also imperative in revegetation success of such degraded landscapes. Different percentage mixtures of T. harzianum in different soils could enhance plant growth depending on the target plant species. Different substrates could thus be used in such revegetation process depending on the target plant species.Revegetation would provide habitat and improve landscape beauty and stability, thus it is important for successful restoration of rock slopes

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Abstract 12091: Novel ECMO Cannulation Strategy Expedites Conversion to LVAD

Circulation ◽

10.1161/circ.130.suppl_2.12091 ◽

2014 ◽

Vol 130 (suppl_2) ◽

Author(s):

Lisa S Foley ◽

T. B Reece ◽

Andreas Brieke ◽

Amrut Ambardekar ◽

Joseph C Cleveland ◽

...

Keyword(s):

Survival Rate ◽

Cardiogenic Shock ◽

Recovery Time ◽

Multiple Organ ◽

High Survival ◽

High Survival Rate ◽

Anterolateral Thoracotomy ◽

Device Implantation ◽

Organ Recovery ◽

Va Ecmo

Objectives: Venoarterial (VA) ECMO has emerged as a successful modality for bridging patients with critical cardiogenic shock to durable support. However, LV distention on ECMO impairs RV and lung recovery and can result in the need for a temporary RVAD. Additionally, patients on VA ECMO with organ dysfunction may require ongoing LV assistance for recovery prior to durable LVAD conversion. Placement of a large apical LV vent allows bedside conversion to LVAD and provides time for organ recovery prior to elective durable device implantation. Hypothesis: We hypothesized that LV venting on ECMO accelerates RV recovery, hastening conversion to LVAD. Methods: ECMO cases from January 2012 to April 2014 were reviewed following IRB approval. Sixteen patients met INTERMACS Category 1 criteria who were placed on VA ECMO for cardiogenic or post-cardiotomy shock. Eight patients had LV venting and eight had standard peripheral cannulation. Refractory pulmonary edema, CPR during cannulation, and severe LV distention were indications for LV venting. A 32 French malleable cannula was placed by limited anterolateral thoracotomy into the LV apex. Bedside LVAD conversion was performed by percutaneous decannulation of the venous line and removal of oxygenator from circuit. Results: Conversion to temporary LVAD was successful in all LV vent cases at a mean timepoint of 5.9 (±1.3) days after LV venting compared with 13.5 (±4.9) days in non-vented patients (p = 0.07). RVAD requirement was 25% in non-vented patients and 0% in vented patients. 30-day mortality was 25% for both groups. Conclusions: LV venting as an adjunct to VA ECMO facilitates RV recovery to enable early LVAD conversion at the bedside. It also provides organ recovery time and obviates the need for a temporary RVAD at the time of durable LVAD implantation. In conclusion, the LV apical venting technique allows staged recovery of critically ill patients in biventricular and multiple organ failure with a high survival rate.

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