scholarly journals Experience of a flu-like illness in the time of COVID-19 and a potential role for turmeric in alleviating symptoms: a case study

2021 ◽  
Vol 2 (1) ◽  
pp. 19
Author(s):  
Kiran Bhadriraju

Turmeric has been known in India since the time of the writing of the Charaka Samhita as a remedy for a wide range of illnesses, including respiratory illnesses. Laboratory investigations in cultured cells in the past several decades have shown that turmeric and its constituents influence signaling pathways and transcription factor activity, changes that are not incompatible with it having a beneficial effect. However, there are currently no rigorously designed modern investigations into the clinical efficacy of turmeric for respiratory illnesses. Here, the consumption of turmeric together with warm milk is anecdotally reported to have provided acute relief from severe congestion during a recent flu-like illness. Since the safety of turmeric has already been demonstrated by thousands of years of use, this report attempts to motivate the direct testing of its clinical efficacy for moderating the severity of flu-like respiratory illnesses in robustly designed clinical trials.

Author(s):  
Hemvati Potdar ◽  
Nutan Radaye

Background: Diabetic Retinopathy is a condition in which prime involvement is of blood vessels. Netratarpana is localized treatment procedure for inner pathological changes in eye disease, it is a noninvasive and very effective measure compare to other treatment procedures available in other pathies. Therefore effort for the reassessment of Netratarpana has been done to understand the efficacy of Jeevantyadi Ghrita in diabetic retinopathy. Objectives: Detail study of Diabetic Retinopathy. Detail study of Jeevantyadi Ghrita Netratarpan and Raktapittahara medicine Methods: A case study of 48yr/male patient showing signs and symptoms of NPDR who is treated with  Jeevantyadi Ghrita Netratarpana along with oral medication for Diabetes.7 days Netratarpana with a follow up for every 15 days up to 2 months. Result: Patient showed improvement in vision along with concern sign and symptoms. Vision improved from C.F 3 feet to 6/36 in Right Eye and in Left Eye from 6/60 to 6/18. Conclusion:  It is observed that Jeevantyadi Ghrita Netratarpana in the patients of diabetic retinopathy plays a potential role and provides immense information with its therapeutic use in wide range of eye disorders especially in the case of diabetic retinopathy.


2021 ◽  
Vol 12 ◽  
Author(s):  
Yating Zhao ◽  
Liu Liu ◽  
Liang Weng

Over the past decade, diverse PD-1/PD-L1 blockades have demonstrated significant clinical benefit in across a wide range of tumor and cancer types. With the increasing number of PD-1/PD-L1 blockades available in the market, differences between the clinical performance of each of them started to be reported. Here, we provide a comprehensive historical and biological perspective regarding the underlying mechanism and clinical performance of PD-1/PD-L1 blockades, with an emphasis on the comparisons of their clinical efficacy and safety. The real-world evidence indicated that PD-1 blockade may be more effective than the PD-L1, though no significant differences were found as regards to their safety profiles. Future head-to-head studies are warranted for direct comparison between them. Finally, we summarize the yet to be elucidated questions and future promise of anti-PD-1/PD-L1 immunotherapy, including a need to explore novel biomarkers, novel combinatorial strategies, and their clinical use on chronic infection.


1974 ◽  
Vol 5 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Peter Krinks

SummaryThe homesteading system instituted in the Philippines in 1903 was intended to stimulate economic development through increased agricultural output from previously unoccupied lands and also to relieve agrarian problems in densely settled parts of the country. A case study shows that while early homesteaders did significantly improve their conditions, the intense demand for land rapidly led to the development of squatting and tenancy. Average farm sizes are declining but there are simultaneously indications of a trend towards concentration of land ownership, which accords with experience in other peasant economies.During the intense concern for economic development over the past 25 or so years, many governments have expressed their faith in the development of new agricultural land as at least a partial answer to a wide range of economic and social problems. These problems include regionally dense populations with inadequate farm sizes, inequitable systems of holding and renting land, inefficient methods of production and marketing, lack of capital and difficulties of capital formation, and low yields from land that is losing fertility through constant cropping. Frequently, ignorance, poverty or the agrarian structure inhibits the adoption of measures for improvement.Those countries with significant areas of little used land resources have tended to rely on developing these resources as an answer to agrarian problems rather than attempting to tackle defects in the whole structure. Since the structure is not changed, it is not surprising that in due course the firmly institutionalised problems of the older areas gradually established themselves in areas of new settlement too. This is essentially what Boeke referred to as “static expansion”. More recently, Mellor has pointed out, “Expanding the land area at constant productivity and incomes is not economic development in the usual sense — it is only a holding action in the face of a growing population”. Even with rising productivity such as associated with the Green Revolution, there is considerable evidence to suggest the continuation, if not exacerbation, of agrarian problems.By examining in detail a case study of colonisation in the Philippines, this paper will show that even if productivity and incomes in a new area are initially high, the operation of customary economic and social processes is likely to ensure the recreation of traditional problems. Such a conclusion is nothing new. It has been repeated depressingly often not only in recent decades but also of course throughout history.


2020 ◽  
Vol 7 (2) ◽  
pp. 326
Author(s):  
Banshi Saboo

The case report describes the potential role of real-time Ambulatory Glucose Profile (AGP) in identifying and managing a patient with hyperglycemia. This 55-years-old male patient with type 2 Diabetes Mellitus (T2DM) was presented to the clinic with weakness, increased urinary frequency, with constipation for the past 3 months. The patient was a known case of T2DM for 10 years, along with dyslipidemia, hypertension, and obesity. The profile obtained from AGP revealed glucose fluctuations with post-prandial excursions. Consequently, the patient’s treatment regimen was changed. The use of glimepiride was discontinued, and the patient was recommended with voglibose 0.2 mg bid with two meals, metformin 100 mg + dapagliflozin 10 mg combination with morning meals, and metformin 1000 mg with evening meals. The treatment for hypertension and dyslipidemia was continued. This case study indicates that CGM can help improve our understanding of glycemic patterns and can have a beneficial effect on glycemic control.


Weed Science ◽  
1992 ◽  
Vol 40 (4) ◽  
pp. 630-635 ◽  
Author(s):  
Paul B. Cavers ◽  
Marguerite Kane ◽  
James J. O'Toole

Proso millet has become a major weed in North America during the past 20 yr. Experiments were conducted to assess the role of the soil seedbank in proso millet's success as a weed. Proso millet has at least eight distinct biotypes, all weeds, which exhibit a wide range of seedbank behavior. At one extreme, weed biotypes resembling crop varieties form transient seedbanks where all viable seed germinate or die before newly ripened seed enter the seedbank. In contrast, the black- and dark-red-seeded biotypes form persistent seedbanks that last several years in the soil. These latter seedbanks differ from those previously described in that there is always a fraction of the seedbank that is not capable of immediate germination. The black-seeded biotype of proso millet can establish a persistent seedbank quickly and that makes the weed very difficult to eradicate.


Daedalus ◽  
2016 ◽  
Vol 145 (2) ◽  
pp. 20-29
Author(s):  
Brooke Holmes

A number of developments in the study of Greek literature over the past few decades have broken down boundaries of canon and genre, opening up a wide range of texts once deemed degenerate or unavailable to literary analysis, expanding the networks within which literary texts are interpreted, and bringing renewed attention to the reception of ancient texts in later periods up to the present. The rise of reception studies, in particular, raises new questions about how our own position within specific present moments not only imposes constraints on the interpretation of ancient texts but also enables it. In this essay, I survey these developments using Greek tragedy, the most canonical of genres, as a case study. I argue that we need to develop strategies of interpretation more attuned to resonances between contemporary quandaries and our extant tragedies while remaining committed to forms of social and historical difference. I pay particular attention to the problems of agency that tragedy raises at the juncture of the human and the nonhuman worlds.


2020 ◽  
Vol 22 (1) ◽  
pp. 65-80 ◽  
Author(s):  
J. B. Carle ◽  
A. Duval ◽  
S. Ashfordc

Although planted forests have produced forest products for centuries, the past 4-5 decades has seen an increase in diversity of species, areas planted, growth rates, harvest yields, forest products and the acknowledgement of a wide range of ecosystem services. This paper highlights the potential role of planted forests towards the mid-21 st Century through changing conditions including climate, indigenous forest resources, land availability, socio economic and environmental conditions, innovative forest and forest industries technologies, market demands for sustainability and legality and new innovations in green growth economies. Lessons learned from the past will assist in determining the issues, opportunities, and challenges facing the future of planted forests.


Author(s):  
A. Strojnik ◽  
J.W. Scholl ◽  
V. Bevc

The electron accelerator, as inserted between the electron source (injector) and the imaging column of the HVEM, is usually a strong lens and should be optimized in order to ensure high brightness over a wide range of accelerating voltages and illuminating conditions. This is especially true in the case of the STEM where the brightness directly determines the highest resolution attainable. In the past, the optical behavior of accelerators was usually determined for a particular configuration. During the development of the accelerator for the Arizona 1 MEV STEM, systematic investigation was made of the major optical properties for a variety of electrode configurations, number of stages N, accelerating voltages, 1 and 10 MEV, and a range of injection voltages ϕ0 = 1, 3, 10, 30, 100, 300 kV).


2020 ◽  
Vol 04 (04) ◽  
pp. 369-372
Author(s):  
Paul B. Romesser ◽  
Christopher H. Crane

AbstractEvasion of immune recognition is a hallmark of cancer that facilitates tumorigenesis, maintenance, and progression. Systemic immune activation can incite tumor recognition and stimulate potent antitumor responses. While the concept of antitumor immunity is not new, there is renewed interest in tumor immunology given the clinical success of immune modulators in a wide range of cancer subtypes over the past decade. One particularly interesting, yet exceedingly rare phenomenon, is the abscopal response, characterized by a potent systemic antitumor response following localized tumor irradiation presumably attributed to reactivation of antitumor immunity.


2020 ◽  
Vol 1 (2) ◽  
pp. 157-172
Author(s):  
Thomas Leitch

Building on Tzvetan Todorov's observation that the detective novel ‘contains not one but two stories: the story of the crime and the story of the investigation’, this essay argues that detective novels display a remarkably wide range of attitudes toward the several pasts they represent: the pasts of the crime, the community, the criminal, the detective, and public history. It traces a series of defining shifts in these attitudes through the evolution of five distinct subgenres of detective fiction: exploits of a Great Detective like Sherlock Holmes, Golden Age whodunits that pose as intellectual puzzles to be solved, hardboiled stories that invoke a distant past that the present both breaks with and echoes, police procedurals that unfold in an indefinitely extended present, and historical mysteries that nostalgically fetishize the past. It concludes with a brief consideration of genre readers’ own ambivalent phenomenological investment in the past, present, and future each detective story projects.


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