Cross-sectional Alignment of Polycyclic Aromatic Hydrocarbons by Anisotropic Radiation

ABSTRACT Objective: analyze the concentration of polycyclic aromatic hydrocarbons in electrocautery smoke in operating rooms and the use of personal protective equipment by the intraoperative team when exposed to hydrocarbons. Method: exploratory and cross-sectional field research conducted in a surgery center. Gases were collected by a vacuum suction pump from a sample of 50 abdominal surgeries in which an electrocautery was used. A form was applied to identify the use of personal protective equipment. Gases were analyzed using chromatography. Descriptive statistics and Spearman's test were used to treat data. Results: there were 17 (34%) cholecystectomies with an average duration of 136 minutes, while the average time of electrocautery usage was 3.6 minutes. Airborne hydrocarbons were detected in operating rooms in 100% of the surgeries. Naphthalene was detected in 48 (96.0%) surgeries and phenanthrene in 49 (98.0%). The average concentration of these compounds was 0.0061 mg/m3 and a strong correlation (0.761) was found between them. The intraoperative teams did not use respirator masks such as the N95. Conclusion: electrocautery smoke produces gases that are harmful to the health of the intraoperative team, which is a concern considering the low adherence to the use of personal protective equipment.

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Does healthy lifestyle attenuate the detrimental effects of urinary polycyclic aromatic hydrocarbons on phenotypic aging? An analysis from NHANES 2001–2010

10.1101/2021.12.17.21268014 ◽

2021 ◽

Author(s):

Zhenqing Yang ◽

Fan Pu ◽

Xingqi Cao ◽

Xueqin Li ◽

Sudan Sun ◽

...

Keyword(s):

Polycyclic Aromatic Hydrocarbons ◽

Aromatic Hydrocarbons ◽

Healthy Lifestyle ◽

Interaction Effects ◽

Potential Interaction ◽

Linear Regression Models ◽

Cross Sectional ◽

Health And Nutrition ◽

Unit Increase ◽

Polycyclic Aromatic

Abstract Objectives: It remains unknown whether healthy lifestyle attenuates the detrimental effects of urinary monohydroxy polycyclic aromatic hydrocarbons (OH-PAHs) on aging. This study aims: 1) to examine the associations of OH-PAHs and lifestyle with Phenotypic Age Acceleration (PhenoAge.Accel), a novel aging measure, respectively; and 2) to evaluate the potential interaction effects of OH-PAHs and lifestyle on PhenoAge.Accel. Methods: Cross-sectional data of 2579 participants (aged 20-84 years, n=1292 females) from the National Health and Nutrition Examination Survey for years 2001-2010 were analyzed. A lifestyle index was constructed based on five components (drinking, smoking, body mass index, physical activity, and diet), ranging from 0 to 5. We calculated PhenoAge.Accel using algorithms developed previously. General linear regression models were used to examine the associations. Results: We observed strong associations of OH-PAHs and lifestyle with PhenoAge.Accel. For instance, one unit increase in ∑NAP (sum of 1- and 2-hydroxynaphthalene) was associated with 0.37 year (95% confidence interval [CI]: 0.26, 0.48) increase in PhenoAge.Accel. We did not observe statistically significant interaction effects between OH-PAHs and lifestyle on PhenoAge.Accel. After stratified by sex, we observed strong associations as well as statistically significant interactions of OH-PAHs and lifestyle with PhenoAge.Accel among females. Conclusions: Both OH-PAHs and lifestyle were independently associated with phenotypic aging and there were statistically significant interactions between OH-PAHs and lifestyle on phenotypic aging among females. The findings highlight the importance of adherence to a healthy lifestyle to attenuate the detrimental effects of exposures to PAHs on phenotypic aging among females.

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