scholarly journals Risk factors associated with drug-resistant tuberculosis in prisons in Sāo Paulo State, Brazil (2006-2016)

2021 ◽  
Vol 15 (11) ◽  
pp. 1661-1669
Author(s):  
Juliane De Almeida Crispim ◽  
Luiz Henrique Arroyo ◽  
Thaís Zamboni Berra ◽  
Felipe Lima dos Santos ◽  
Ludmilla Leidianne Limirio Souza ◽  
...  
Keyword(s):  
Sao Paulo ◽  
Sputum Culture ◽  
Drug Resistant ◽  
São Paulo ◽  
Drug Resistant Tuberculosis ◽  
Factors Associated ◽  
Paulo State ◽  
Treatment History ◽  
Resistant Tuberculosis ◽  
São Paulo State

Introduction: Prisons are high-risk settings for drug-resistant tuberculosis because the prevalence of the tuberculosis (TB) is much higher than in the general population. This study to investigated the factors associated with drug-resistant tuberculosis in prisons in the state of São Paulo, Brazil. Methodology: Retrospective cohort of drug-resistant TB cases for incarcerated people in São Paulo state, reported in the Tuberculosis Patient Control System between 2006 and 2016. To analyze the factors associated with drug-resistant TB, the backward method (likelihood ratio) was used, determining the adjusted odds ratio and respective 95%CI coefficients. Multiple models were proposed to adjust for potential confusion and interaction. The best fit model was selected based on the lowest Akaike information criterion coefficient. Results: In total, 473 drug-resistant tuberculosis cases were reported in the prison population of Sāo Paulo state, the majority were male. The cases that presented negative results for sputum smear and sputum culture had, respectively, an aOR=0.6 and aOR=0.16 for drug-resistant tuberculosis in relation to the cases with positive results. The cases where the patient had AIDS and reported alcoholism, respectively, an aOR=1.47 and aOR=1.60 for drug-resistant TB. Individuals with a background treatment history for TB presented a stronger association with drug-resistant tuberculosis, aOR=35.08. Conclusions: Sputum spear, sputum culture, chest X-ray, AIDS, alcoholism and background treatment history for TB were factors associated with resistance to antituberculosis drugs among prisoners. This is useful for the implementation of disease control measures related to the detection and monitoring of cases in the prison system.

Factors associated with Diaphorina citri immigration into commercial citrus orchards in São Paulo State, Brazil

2020 ◽  
Author(s):  
Fernando P. F. Zorzenon ◽  
Arthur F. Tomaseto ◽  
Matthew P. Daugherty ◽  
João R. S. Lopes ◽  
Marcelo P. Miranda
Keyword(s):  
Sao Paulo ◽  
São Paulo ◽  
Diaphorina Citri ◽  
Factors Associated ◽  
Paulo State ◽  
São Paulo State ◽  
Citrus Orchards

scholarly journals A DECADE TREND OF MULTIDRUG RESISTANT TUBERCULOSIS IN SÃO PAULO STATE, BRAZIL

2016 ◽  
Vol 58 (0) ◽  
Author(s):  
Valdes Roberto BOLLELA ◽  
Fernanda Guioti PUGA ◽  
Maria Janete MOYA ◽  
Mauro ANDREA ◽  
Maria de Lourdes Viude OLIVEIRA
Keyword(s):  
Multidrug Resistant ◽  
Sao Paulo ◽  
São Paulo ◽  
Paulo State ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
São Paulo State

scholarly journals The challenge of managing extensively drug-resistant tuberculosis at a referral hospital in the state of São Paulo, Brazil: a report of three cases

2015 ◽  
Vol 41 (6) ◽  
pp. 554-559 ◽  
Author(s):  
Marcos Abdo Arbex ◽  
Hélio Ribeiro de Siqueira ◽  
Lia D'Ambrosio ◽  
Giovanni Battista Migliori
Keyword(s):  
Sao Paulo ◽  
The State ◽  
Referral Hospital ◽  
World Health ◽  
Drug Resistant ◽  
São Paulo ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant ◽  
Laboratory Test Results

ABSTRACT Here, we report the cases of three patients diagnosed with extensively drug-resistant tuberculosis and admitted to a referral hospital in the state of São Paulo, Brazil, showing the clinical and radiological evolution, as well as laboratory test results, over a one-year period. Treatment was based on the World Health Organization guidelines, with the inclusion of a new proposal for the use of a combination of antituberculosis drugs (imipenem and linezolid). In the cases studied, we show the challenge of creating an acceptable, effective treatment regimen including drugs that are more toxic, are more expensive, and are administered for longer periods. We also show that treatment costs are significantly higher for such patients, which could have an impact on health care systems, even after hospital discharge. We highlight the fact that in extreme cases, such as those reported here, hospitalization at a referral center seems to be the most effective strategy for providing appropriate treatment and increasing the chance of cure. In conclusion, health professionals and governments must make every effort to prevent cases of multidrug-resistant and extensively drug-resistant tuberculosis.

scholarly journals 0280 Factors associated with the severity of work injuries in the formal sector in piracicaba, são paulo state, brazil

2017 ◽  
Author(s):  
Mariana Tavares Guimarães ◽  
Ana Paula Sacone da Silva Ferreira ◽  
Alessandro José Nunes da Silva ◽  
Sandra Renata Duracenko ◽  
Stela Verzinhasse Peres ◽  
...  
Keyword(s):  
Sao Paulo ◽  
São Paulo ◽  
Formal Sector ◽  
Work Injuries ◽  
Factors Associated ◽  
Paulo State ◽  
São Paulo State

Breastfeeding, genetic, obstetric and other risk factors associated with mother-to-child transmission of HIV-1 in Sao Paulo State, Brazil

AIDS ◽  
1998 ◽  
Vol 12 (5) ◽  
pp. 513-520 ◽  
Author(s):  
Beatriz H. Tess ◽  
Laura C. Rodrigues ◽  
Marie-Louise Newell ◽  
David T. Dunn ◽  
Tania D.G. Lago
Keyword(s):  
Risk Factors ◽  
Sao Paulo ◽  
São Paulo ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Factors Associated ◽  
Paulo State ◽  
São Paulo State ◽  
Mother To Child ◽  
Hiv 1

Spatial and sociodemographic factors associated with surgical site infection rates in hospitals in inner São Paulo State, Brazil

2021 ◽  
Vol 108 ◽  
pp. 181-184
Author(s):  
A.G.M.L. Carvalho ◽  
D.C. Limaylla ◽  
T.N. Vilches ◽  
G.B. de Almeida ◽  
G. Madalosso ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Sociodemographic Factors ◽  
Sao Paulo ◽  
São Paulo ◽  
Site Infection ◽  
Infection Rates ◽  
Factors Associated ◽  
Paulo State ◽  
São Paulo State

scholarly journals Population structure and circulating genotypes of drug-sensitive and drug-resistant Mycobacterium tuberculosis clinical isolates in São Paulo state, Brazil

2013 ◽  
Vol 14 ◽  
pp. 39-45 ◽  
Author(s):  
Maria Conceição Martins ◽  
Carmen M. Saraiva Giampaglia ◽  
Rosângela S. Oliveira ◽  
Vera Simonsen ◽  
Fábio Oliveira Latrilha ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Population Structure ◽  
Sao Paulo ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
São Paulo ◽  
Paulo State ◽  
São Paulo State

scholarly journals American Visceral Leishmaniasis: Factors Associated with Lethality in the State of São Paulo, Brazil

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Geraldine Madalosso ◽  
Carlos Magno Fortaleza ◽  
Ana Freitas Ribeiro ◽  
Lisete Lage Cruz ◽  
Péricles Alves Nogueira ◽  
...  
Keyword(s):  
Data Analysis ◽  
Visceral Leishmaniasis ◽  
Clinical Laboratory ◽  
Univariate Analysis ◽  
Sao Paulo ◽  
São Paulo ◽  
Disease Evolution ◽  
Factors Associated ◽  
Paulo State ◽  
São Paulo State

Objectives. To identify factors associated with death in visceral leishmaniasis (VL) cases.Patients and Methodology. We evaluated prognostic factors for death from VL in São Paulo state, Brazil, from 1999 to 2005. A prognostic study nested in a clinical cohort was carried out by data analysis of 376 medical files. A comparison between VL fatal cases and survivors was performed for clinical, laboratory, and biological features. Association between variables and death was assessed by univariate analysis, and the multiple logistic regression model was used to determine adjusted odds ratio for death, controlling confounding factors.Results. Data analysis identified 53 fatal cases out of 376 patients, between 1999 and 2005 in São Paulo state. Lethality was 14.1% (53/376), being higher in patients older than fifty years. The main causes of death were sepsis, bleeding, liver failure, and cardiotoxicity due to treatment. Variables significantly associated with death were severe anemia, bleeding, heart failure, jaundice, diarrhea, fever for more than sixty days, age older than fifty years, and antibiotic use.Conclusion. Educational health measures are needed for the general population and continuing education programs for health professionals working in the affected areas with the purpose of identifying and treating early cases, thus preventing the disease evolution towards death.

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