scholarly journals Acupuncture Treatment of Subfertility and Ovarian Endometrioma

2018 ◽  
Vol 6 (3) ◽  
pp. 519-522
Author(s):  
Jihe Zhu ◽  
Blagica Arsovska ◽  
Andrijana Sterjovska-Aleksovska ◽  
Kristina Kozovska
Keyword(s):  
Ovarian Function ◽  
Acupuncture Treatment ◽  
Treated Patient ◽  
Treatment Options ◽  
Uterine Cavity ◽  
Physical Factors ◽  
Ovarian Endometrioma ◽  
Du Mai ◽  
Ren Mai ◽  
Positive Results

BACKGROUND: Ovarian endometriotic cysts, also known as ‘chocolate’ cysts or ovarian endometriomas, appear as endometrial tissue outside the uterine cavity which grows inside ovaries. Endometriotic cysts can cause chronic pelvic pain, dysmenorrhea, dyspareunia, impairment of ovarian function in regards to subfertility, etc. Traditional Chinese Medicine (TCM) is effectively treating subfertility associated with endometriosis for years, and the treatment gives positive results in achieving pregnancy. With the acupuncture treatment, blood circulation is promoted, external physical factors - eliminated, the stasis is dissolved, the menstrual cycle is regulated, and inflammation is diminished.CASE REPORT: Our treated patient is 29-year-old woman diagnosed with ovarian endometrioma, slightly - elevated prolactin levels and inability to get pregnant after trying for two years. 19 acupuncture treatments were done on the meridians of Pericardium, Spleen, Stomach, Liver, Ren Mai, Kidney, Large intestine, Du Mai and Bladder. After the acupuncture treatments, the endometrioma was decreased in size and the patient got pregnant spontaneously in a short period.CONCLUSION: Acupuncture, as part of the TCM, gives positive results and can successfully add up to variety of non - surgical infertility treatment options in women with endometrioma(s).

scholarly journals Acupuncture Treatment in Patient with Uterine Polyp

2018 ◽  
Vol 3 (12) ◽  
Author(s):  
Prof Dr Jihe Zhu ◽  
BSc Blagica Arsovska ◽  
BSc Kristina Kozovska
Keyword(s):  
Room Temperature ◽  
Acupuncture Treatment ◽  
Treated Patient ◽  
Uterine Cavity ◽  
Endometrial Polyps ◽  
Younger Women ◽  
Kidney Deficiency ◽  
Positive Results ◽  
Uterine Polyps ◽  
Over Time

Uterine polyps are benign growths on the inner wall of the uterus, which extend into the uterine cavity. Excessive growth of the mucous membrane of the uterus (endometrium) leads to the formation of polyps on the uterus. Uterine polyps are usually non-cancerous (benign), although some may be carcinogenic or possibly develop over time into cancer. Polyps can be divided into two groups: endo-cervical polyps and endometrial polyps. Uterine polyps most commonly occur in women who undergo menopause or are in postmenopausal period, although polyps may occur in younger women too. In Traditional Chinese Medicine (TCM), the cause for uterine polyps is usually a combination of Blood deficiency, Blood stagnation and Liver/Kidney Deficiency. The aim of the treatment is to move the blood, to make the blood flow free and smooth, resolve the dampness, resolve the blood stagnation, treat the underlying deficiencies and etc. The treated patients is 41 year old woman, diagnosed with 10 mm uterine polyp. The patient was also diagnosed with infertility and was having irregular periods. The patient was treated with acupuncture in a clinic for TCM and acupuncture in Skopje. In a period of 4 months, 14 treatments were made, indoor, on a room temperature, with duration of the treatments of 30-45 minutes. After the 4th treatment her period was regularized and after 14 treatments the polyp was gone. Acupuncture as a treatment for uterine polyps is safe and effective treatment and gave very satisfying and positive results in our treated patient.

scholarly journals Acupuncture treatment in menstrual disorder after oocyte donation

2018 ◽  
Vol 4 (8) ◽  
pp. 208
Author(s):  
Jihe Zhu ◽  
Blagica Arsovska ◽  
Kristina Kozovska
Keyword(s):  
Acupuncture Treatment ◽  
Treated Patient ◽  
Oocyte Donation ◽  
The Body ◽  
Third Party ◽  
Egg Donation ◽  
Vitro Fertilization ◽  
Menstrual Disorder ◽  
Du Mai

<p class="abstract">Oocyte donation or egg donation is a process in which one woman donates eggs (oocytes) to another women in order to conceive. The process involves in vitro fertilization and it is seen as third party reproduction in the assisted reproductive technology. The oocytes from the donor are combined with the spermatozoa from the recipient to produce embryos. However, the treatment has some risk factors that afterwards need to be taken care of. One of the complications is delayed or stopped period and the acupuncture treatment can efficiently solve this problem. The treated patient is a 34 year old woman with 3 months delay in the period after receiving hormone therapy for egg donation. The patient was treated with normal needle acupuncture on the meridians of spleen, kidney, pericardium, stomach, liver, large intestine, bladder, ren mai and du mai. Treatments were made indoor, with duration of 35-40 minutes both sides of the body. In the treatment were used fine sterile disposable needles. After only one treatment the period was back and normalized. The patient has made 6 treatments. After the 6<sup>th</sup> treatment the second period was normal again. Acupuncture treatment as part of the 5000 years old Traditional Chinese Medicine, as in many other menstrual disorders, it is as well successful treatment in menstrual disorder after egg donation and gives very satisfying and positive results in a very short time.</p>

scholarly journals Extended adverse effects of cyclophosphamide on mouse ovarian function

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jihyun Kim ◽  
Sooseong You
Keyword(s):  
Adverse Effects ◽  
Cancer Survivors ◽  
Cancer Survival ◽  
Ovarian Function ◽  
Treatment Options ◽  
Bioinformatics Analyses ◽  
Hormonal Stimulation ◽  
Patients With Cancer ◽  
Multiple Exposures

Abstract Purpose Most patients with cancer undergo multiple administrations of anticancer drugs during treatment, resulting in chronic impairment of their reproductive health. As improved treatment options increase cancer survival, it has become increasingly important to address fertility issues in cancer survivors. In this study, we examined the pathophysiological effects of multiple exposures to cyclophosphamide (Cy) on the ovaries of mice and their underlying molecular mechanism. Methods Female C57BL/6 mice were intraperitoneally injected with 100 mg/kg Cy six times over 2 weeks; 4 weeks later, the mice were sacrificed and their ovaries, sera, and oocytes were collected for histological observation, measurement of anti-Müllerian hormone levels, and assessment of oocyte quantity and quality in response to hormonal stimulation. Gene expression changes in Cy-treated ovaries were examined by microarray and bioinformatics analyses. Results After repeated Cy exposure, the anti-Müllerian hormone level was decreased, and follicle loss and impairments in the quality of oocyte were irreversible. The expression levels of genes involved in folliculogenesis, oogenesis, and zona pellucida glycoprotein transcription displayed sustained alterations in Cy-exposed ovaries even after 4 weeks. Conclusion The adverse effects of Cy on ovarian function and oocytes remained even after chemotherapy was complete. Therefore, strategies to prevent ovarian damage or restore ovarian function after treatment are required to safeguard the fertility of young cancer survivors.

scholarly journals The Modern Landscape of Endocrine Therapy for Premenopausal Women with Breast Cancer

Breast Care ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. 312-315 ◽  
Author(s):  
Lorenzo Rossi ◽  
Olivia Pagani
Keyword(s):  
Breast Cancer ◽  
Endocrine Therapy ◽  
Ovarian Function ◽  
Treatment Options ◽  
Endocrine Resistance ◽  
Premenopausal Women ◽  
New Drugs ◽  
Fine Tuning ◽  
Individual Risk ◽  
Ovarian Function Suppression

The optimal endocrine therapy for premenopausal women with early and advanced breast cancer still remains an important and controversial issue. For over 30 years, tamoxifen has been the gold standard in the adjuvant setting. New therapeutic options, such as the addition of ovarian function suppression to oral endocrine therapy (either tamoxifen or aromatase inhibitors), can improve outcomes over tamoxifen alone in well-selected patients. Treatment duration has also been revisited, and extended therapy is becoming a new standard of care, especially in high-risk patients. Endocrine therapy for advanced disease still represents a challenge and a research priority. New drugs and combinations able to overcome endocrine resistance are at the horizon, and their role in premenopausal women should be better elucidated. Side effects and quality of life (including family planning considerations) play an important role in treatment selection and in the patients' treatment adherence and should always be discussed before start of treatment. The paper will specifically focus on how to integrate all new treatment options in the current armamentarium of endocrine therapy of premenopausal women, with the aim of best fine-tuning treatment selections according to the individual risk/benefit evaluation.

Spinal artery aneurysms: clinical presentation, radiological findings and outcome

2018 ◽  
Vol 10 (7) ◽  
pp. 644-648 ◽  
Author(s):  
Leonardo Renieri ◽  
Eytan Raz ◽  
Giuseppe Lanzino ◽  
Timo Krings ◽  
Maksim Shapiro ◽  
...  
Keyword(s):  
Back Pain ◽  
Retrospective Review ◽  
Clinical Presentation ◽  
Treated Patient ◽  
Demographic Data ◽  
Treatment Options ◽  
Treatment Strategies ◽  
Imaging Characteristics ◽  
Arterial Aneurysms

Background and purposeSpinal arterial aneurysms are a rare cause of spinal subarachnoid hemorrhage (SAH). We performed a retrospective review of spinal arterial aneurysms not associated with spinal arteriovenus shunts from three institutions in order to better understand the clinical and imaging characteristics of these lesions.Materials and methodsWe performed a retrospective review of spinal arterial aneurysms managed at three North American institutions. For each patient, the following information was collected: demographic data, clinical presentation, comorbidities, imaging findings, and neurological status at the last follow-up. Treatment strategies and outcomes were reported.Results11 patients were included; 7 were women and median age was 60 years. The most common presentation was sudden back pain (81.8%). We found 3 aneurysms on the radiculomedullary artery and 8 along the radiculopial arteries. Of the 3 aneurysms on the radiculomedullary artery, 1 was treated conservatively, 1 was treated with coiling of the aneurysm and sacrifice of the radiculomedullary artery, and 1 was treated with surgical trapping. The 8 aneurysms on the radiculopial artery were treated endovascularly in 4 cases, surgically in 1 case, and conservatively in 3 cases. One surgically treated patient had a spinal subdural hematoma. There were no other complications. Mean clinical follow-up time was 20 months, and 87.5% of patients were functionally independent.ConclusionsSpinal arterial aneurysms are lesions which commonly present with sudden back pain and spinal SAH. Conservative, surgical, and endovascular treatment options are safe and effective. Long term outcomes in these patients are generally good.

scholarly journals Histamine Intolerance in Children

2021 ◽  
Author(s):  
Wojciech Nazar ◽  
Katarzyna Plata-Nazar ◽  
Katarzyna Sznurkowska ◽  
Agnieszka Szlagatys-Sidorkiewicz
Keyword(s):  
Diamine Oxidase ◽  
Treatment Options ◽  
Gastrointestinal Symptoms ◽  
Diagnostic Algorithm ◽  
Diagnostic Challenge ◽  
Male Predominance ◽  
Provocation Tests ◽  
Histamine Intolerance ◽  
Bowel Diseases ◽  
Positive Results

Histamine intolerance is defined as disequilibrium of accumulated histamine and the capacity for histamine degradation. This clinical term addresses a non-immunologically mediated pathology when histamine ingested with food is not particularly high, but its degradation is decreased. Clinical picture of histamine intolerance in children is similar to that observed in adults apart from male predominance found in paediatric patients. Both in children and adults, histamine-free diet seems to be the treatment of choice. Diamine oxidase supplementation offers another treatment option. There is no symptom and\or test pathognomonic for histamine intolerance. Nevertheless, manifestations of chronic gastrointestinal symptoms, measurement of diamine oxidase deficits, positive results of histamine provocation tests and improvement of symptoms with histamine-free diet greatly increase the probability of histamine intolerance diagnosis. These factors have been included in the proposed in this paper diagnostic algorithm for histamine intolerance. In children histamine intolerance probably co-occur with allergies and bowel diseases, which creates an additional diagnostic challenge. As the evidence for children is weak, further research is needed the establish epidemiology, validate diagnostic algorithms and establish possible treatment options regarding histamine intolerance.

Changes of skin electrical potential in acupoints from Ren Mai and Du Mai conduits during Qigong practice: Documentation of a clinical phenomenon

2019 ◽  
Vol 23 (4) ◽  
pp. 713-720 ◽  
Author(s):  
Luís Carlos Matos ◽  
Jorge Machado ◽  
Henry Johannes Greten ◽  
Fernando Jorge Monteiro
Keyword(s):  
Electrical Potential ◽  
Clinical Phenomenon ◽  
Du Mai ◽  
Ren Mai

Iatrogenic Endometriosis and Intrauterine Adhesions after Myomectomy

2016 ◽  
Vol 8 (3) ◽  
pp. 236-238
Author(s):  
Farheen Yousuf
Keyword(s):  
South Asian ◽  
Uterine Cavity ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Resonance Imaging ◽  
Intrauterine Adhesions ◽  
Ovarian Endometrioma ◽  
Imaging Results ◽  
Endometrial Cavity ◽  
Cut Surface

ABSTRACT Aims To report a case of iatrogenic endometrioses as a result of improper closure of endometrial cavity during myomectomy. Case Report A 30-year-old para 1 has been self-referred to our institution for medical care. A fibroid protruding the endometrial canal was removed 8 months prior to this hospital admission. In less than a month after initial myomectomy, she began experiencing severe pelvic pain more accentuated during menstruation. The pain became progressively worse. The magnetic resonance imaging results are suggestive of ovarian endometrioma. She underwent total abdominal hysterectomy and bilateral salpingo-oophrectomy. Cut surface of uterine cavity shows obliteration of endometrial canal with hourglass constriction. Conclusion Closure of endometrium during myomectomy should be carefully done; keeping an account on patency of endometrial canal is essential to prevent iatrogenic endometriosis. How to cite this article Yousuf F. Iatrogenic Endometriosis and Intrauterine Adhesions after Myomectomy. J South Asian Feder Obst Gynae 2016;8(3):236-238.

scholarly journals Extended Adverse Effects of Cyclophosphamide on Mouse Ovarian Function

2020 ◽  
Author(s):  
Jihyun Kim ◽  
Sooseong You
Keyword(s):  
Adverse Effects ◽  
Cancer Survivors ◽  
Cancer Survival ◽  
Ovarian Function ◽  
Treatment Options ◽  
Bioinformatics Analyses ◽  
Hormonal Stimulation ◽  
Patients With Cancer ◽  
Multiple Exposures

Abstract Background: Most patients with cancer undergo multiple administrations of anticancer drugs during treatment, resulting in chronic impairment of their reproductive health. As improved treatment options increase cancer survival, it has become increasingly important to address fertility issues in cancer survivors. In this study, we examined the pathophysiological effects of multiple exposures to cyclophosphamide (Cy) on the ovaries of mice and their underlying molecular mechanism. Methods: Female C57BL/6 mice were intraperitoneally injected with 100 mg/kg Cy six times over 2 weeks; 4 weeks later, the mice were sacrificed and their ovaries, sera, and oocytes were collected for histological observation, measurement of anti-Müllerian hormone levels, and assessment of oocyte quantity and quality in response to hormonal stimulation. Gene expression changes in Cy-treated ovaries were examined by microarray and bioinformatics analyses. Results: After repeated Cy exposure, the anti-Müllerian hormone level was decreased, and follicle loss and impairments in the quality of oocyte were irreversible. The expression levels of genes involved in folliculogenesis, oogenesis, and zona pellucida glycoprotein transcription displayed sustained alterations in Cy-exposed ovaries even after 4 weeks.Conclusion: The adverse effects of Cy on ovarian function and oocytes remained even after chemotherapy was complete. Therefore, strategies to prevent ovarian damage or restore ovarian function after treatment are required to safeguard the fertility of young cancer survivors.

scholarly journals Medikamentozno zdravljenje endometrioze: pregled stanja in nove možnosti zdravljenja

2016 ◽  
Vol 85 (7-8) ◽  
Author(s):  
Maja Jakič ◽  
Andrej Vogler ◽  
Tea Lanišnik Rižner
Keyword(s):  
Surgical Treatment ◽  
Treatment Options ◽  
Uterine Cavity ◽  
Pharmacological Treatments ◽  
Gynecological Examination ◽  
Combination Studies ◽  
Hormonal System ◽  
Gynecological Disease ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Endometriosis is a gynecological disease that is defined as the presence of endometrium-like tissue outside the uterine cavity, and it is one of the main causes of female infertility. Although there is unfortunately no known ‘optimal’ treatment for endometriosis, there are three treatment options: medication, surgical treatment, and a combination of both. The gold standard for diagnosis of endometriosis is a diagnostic laparoscopy, which is also therapeutic. Indications for pharmacological treatment of endometriosis include empirical treatment for patients with pelvic pain who are normal on gynecological examination, or who have recurrent disease after surgical treatment or in combination with surgical treatment. In everyday practice, non-steroid anti-inflammatory drugs, oral contraceptives, and progestins per os are used as first-line pharmacological treatments of endometriosis. Gonadoliberin agonists can be used as second-line treatment, although their use is discouraged. These medications can be used alone or in combination. Studies over the last 10 years have shown that many other agents have potential for treatment of endometriosis. These can be broadly classified into several groups: anti-inflammatory agents, and agents that interfere with the hormonal system, or with other pathophysiological processes, such as a disturbed immune system, reduced apoptosis, enhanced angiogenesis, degradation of the extracellular matrix, increased oxidative stress, and epigenetic changes. However, their introduction into routine use requires more convincing clinical studies to confirm their effectiveness.

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