scholarly journals Micropapillary Adenocarcinoma of the Lung that Metastasized to the Same Site in the Brain Twice: A Rare Case Report and Review of Literature

2020 ◽  
Vol 8 (C) ◽  
pp. 184-187
Author(s):  
Ahmad Faried ◽  
Rhonaz P. Agung ◽  
Hasrayati Agustina ◽  
Bethy S. Hernowo ◽  
Muhammad Z. Arifin

BACKGROUND: Adenocarcinoma (ADC) of the lung is the most common subtype of non-small cell lung cancer (NSCLC), occurring in ~40% of all patients with significantly higher incidence of brain metastasis compared with other subtypes of NSCLC. Among the five subtypes ADC of the lung, micropapillary predominant ADC may be more likely to metastasize. There are almost no reports of micropapillary ADC of the lung initially discovered to metastasis into the same site in the brain that has been previously operated. CASE REPORT: We reported a 54-year-old woman who was referred to ICU of Dr. Hasan Sadikin Hospital, Bandung, due to a decreased of consciousness. Head computed tomography scan revealed multiple isohypodense lesions in the right frontal with brain edema. She had craniotomy total tumor removal 8 months earlier and diagnosed as brain metastasis due to micropapillary ADC of the lung. She refused to receive chemoradiotherapy. At the operation site, multilobulated lesions were found, and hence, she was operated for the 2nd time at the same site with the first one, exhibited the same histology. Immunohistological shown positive results for thyroid transcription factor (TTF)-1 and cytokeratin (CK)-7; negative for CK-20, led to a diagnosis of micropapillary ADC of the lung. CONCLUSION: Herein, we reported our experience regarding a case of micropapillary ADC of the lung, considered as poorly differentiated ADC and associated with a high-grade lesion that metastasized to the same site that had been previously operated, twice. A definitive diagnosis was possible only through a histopathological examination along with a good communication between the surgeon and the pathologist.

2021 ◽  
pp. 15-16
Author(s):  
Rahmath Unissa ◽  
Amreen Unissa ◽  
M. Bhavani

we report a case of 51 year old lady, presented with complaints of hard lump in the right breast.On clinical examination lump of size 4x3cms in outer lower quadrant was noted. Ultrasonographic imaging showed evidence of 3x2cms ill dened hypoechoic lesion with spiculated margins and microcalcications. Trucut biopsy was done and histopathological report was given as Suspicious for malignancy which was followed by modied radical mastectomy with axillary clearance. Histopathological examination and Immunohistochemistry(IHC) was done.


2021 ◽  
Vol 10 (34) ◽  
pp. 2939-2941
Author(s):  
Jiby Soosen Ninan ◽  
Ajithakumari K. ◽  
Tony Mathew

Primary cutaneous mucinous carcinoma (PCMC) also known as primary mucinous carcinoma of the skin (PMCS) or primary mucinous eccrine carcinoma (PMEC) is a rare malignant adnexal tumour of eccrine origin. Many visceral mucinous carcinomas especially of the breast and gastrointestinal tract can metastasize to the skin mimicking PCMC. Hence it is very important to rule out metastatic mucinous carcinomas before making a diagnosis of PCMC. Usually, PCMC presents as a slowgrowing tumour of considerably smaller size compared to our case. The large size and shorter duration are the key features of this case report. Here we report an unusually large-sized rare malignant tumour of skin appendage. Our patient was a 54-year-old lady who presented with progressive swelling of one year duration in the right frontoparietal area. Ultrasonography showed an ill-defined lesion in the subcutaneous plane with multiple cystic spaces within it. No bone involvement was noted. The excised lesion measured 13 x 7 x 2 cms and was diagnosed as primary cutaneous mucinous carcinoma on histopathological examination. The possibility of cutaneous secondaries from elsewhere was ruled out by detailed clinical and radiological investigations. The case is reported considering the unusually bigger size and shorter duration of this rare entity.


Author(s):  
Pradeep Rajbhandari ◽  
Roshani Shrestha

<p>Lipoma is a benign mesenchymal tumour which is composed of mature adipocytes. This is one of the most common benign neoplasms of the body. However, lipoma is uncommon in oral cavity. The etiology and pathoge­nesis of lipomas are not clear. Our case report presents a 26 year old male presenting with swelling in the right gingivo-buccal sulcus. Complete excision of the mass was done and sent for histopathological examination and histological features were suggestive of lipoma.</p>


2017 ◽  
Vol 9 (3) ◽  
pp. 104-108
Author(s):  
Sabri Özden ◽  
Aysel Colak ◽  
Baris Saylam ◽  
Ömer Cengiz

ABSTRACT Introduction Neuroendocrine tumors (NETs) of the thyroid are rare tumors. Medullary thyroid carcinoma (MTC) is an exact NET of the thyroid gland, arising from the parafollicular cells (C cells). It has unique features like immunohistochemically and biochemically calcitonin positivity and amyloid deposits. In this case report, a rare thyroid tumor is presented, which has neuroendocrine staining properties and does not produce serum or cytoplasmic calcitonin. Case report The patient was a 45-year-old woman who underwent total thyroidectomy because of the countless multiple thyroid nodules and a suspicion about a nodule at the right lobe. On histopathological examination, there was a tumor in the left thyroid lobe that measured 0.4 cm. Tumor immunohistochemical staining was positive for synaptophysin, chromogranin A (neuroendocrine cell markers), and thyroglobulin (Tg), and thyroid transcription factor-1 (TTF-1; follicular cell markers). The staining was negative for calcitonin. Conclusion There are thyroid tumors that are calcitonin-negative and Tg-positive called calcitonin-negative NETs. Careful interpretation and distinction between MTCs are needed at these tumors because they may have different biologic behaviors, and calcitonin negativity makes follow-up of patients challenging. How to cite this article Özden S, Colak A, Saylam B, Cengiz Ö. Primary Calcitonin-negative Neuroendocrine Tumor. World J Endoc Surg 2017;9(3):104-108.


VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.


2015 ◽  
Vol 6 (3) ◽  
pp. 115-117
Author(s):  
Sachin Lal Shilpakar ◽  
Bivek Aryal ◽  
Shyam Thapa Chettri ◽  
Apar Pokharel ◽  
Deepak Paudel

ABSTRACT The trichoepithelioma is a benign cutaneous neoplasm which is derived from hair follicles. It is common in the face, but there are only three reports of the solitary occurrence on the nose. It is often not recognized because of its rarity, controversial classification, origin and biological potential. The objective of this paper is to present a case of solitary trichoepithelioma on the nose, histopathological examination and treatment. It should be considered as a differential diagnosis of a solitary lesion of nose which is confused with basal cell carcinoma. The confirmation by histopathological examination is essential. How to cite this article Sah BP, Shilpakar SL, Aryal B, Chettri ST, Pokharel A, Mishra S, Paudel D. Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature. Int J Head Neck Surg 2015;6(3):115-117.


Author(s):  
Asma Beyki ◽  
Mahmud Zardast ◽  
Zahra Nasrollahi

Invasive aspergillosis of the paranasal sinuses is a rare and often misdiagnosed disease. This study reported a case of max- illary aspergillosis with a complete  headache and eye pain after tooth extraction with a large abscess in the relative jaw. Tenderness in the right temporal, lower jaw numbness and right eye proptosis was found. Histopathological examination was the suggestion of maxillary sinusitis with a fungal ball of aspergillus.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Haider Alyousef ◽  
Elsawi M. Osman ◽  
Mohamed A. Gomha

Introduction. Liposarcoma is a rare pathological entity. By far it is the most common histological subtype of genitourinary sarcomas in adults. Approximately two hundred cases were reported in the literature. We are hereby presenting a case with a typical clinical scenario of paratesticular liposarcoma.Case report. A 75-year-old gentleman presented with a painless right hemiscrotal swelling that was progressively increasing in size over the last 6 years. Testicular tumour markers were negative. Imaging showed a heterogenous mass with fat component. Subsequently he underwent wide local excision that included the paratesticular mass along with the right testicle and all right inguinal canal contents up to the deep inguinal ring with the sparing of right illioinguinal nerve. Histopathological examination showed a well differentiated liposarcoma of the spermatic cord. He remained recurrence-free so far after 18 months of followup.Conclusion. Radical orchidectomy with wide local excision comprises the cornerstone of treatment of paratesticular liposarcoma. Due to the rarity of the disease there is no definite universal consensus of opinion as regards the role of radiotherapy and chemotherapy.


Author(s):  
David Breuskin ◽  
Ralf Ketter ◽  
Joachim Oertel

Abstract Background Although intracranial traumas by penetrating foreign objects are not absolute rarities, the nature of trauma, the kind of object, and its trajectory make them a one of a kind case every time they occur. Whereas high-velocity traumas mostly result in fatalities, it is the low-velocity traumas that demand an individualized surgical strategy. Methods We present a case report of a 33-year-old patient who was admitted to our department with a self-inflicted transorbital pen injury to the brain. The authors recall the incident and the technique of the pen removal. Results Large surgical exposure of the pen trajectory was considered too traumatic. Therefore, we opted to remove the pen and have an immediate postoperative computed tomography (CT) scan. Due to its fragility, the pen case could only be removed with a screwdriver, inserted into the case. Post-op CT scan showed a small bleeding in the right peduncular region, which was treated conservatively. The patient was transferred back to intensive care unit and woken up the next day. She lost visual function on her right eye, but suffered from no further neurologic deficit. Conclusion Surgical management of removal of intracranial foreign bodies is no routine procedure. Although some would favor a large surgical exposure, we could not think of an approach to do so without maximum surgical efforts. We opted for a minimal surgical procedure with immediate CT scan and achieved an optimal result. We find this case to be worth considering when deciding on a strategy in the future.


2019 ◽  
Vol 10 (02) ◽  
pp. 367-370
Author(s):  
Shamila Mohamed Ali ◽  
P. Somashekara Reddy ◽  
S. Venugopal ◽  
Manmeet Chhabra ◽  
Anita Mahadevan

ABSTRACTHuman coenurosis is a rare zoonotic disease caused by the larvae of Tinea multiceps seen in sheep-rearing countries. We report the case of a 63-year-old male who was referred to our hospital with a working diagnosis of skull base chondrosarcoma. Histopathological examination after surgical excision revealed characteristic feature of coenurus with multiple scolices invaginating from the outer cuticular layer. Coenuri are often mistaken for giant cysticercal cysts and hydatid cysts. Despite its wide prevalence in cattle, only two cases of human coenurosis are reported from India till date. We report the third case from India.


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