scholarly journals The Impact of Resistance Training on Gene Expression of IGF1 and Athletes’ Physiological Parameters

2021 ◽  
Vol 9 (A) ◽  
pp. 934-940
Author(s):  
Mohammed Nader Shalaby ◽  
Mona Mostafa Abdo Sakoury ◽  
Ellie Abdi ◽  
Shaimaa Elgamal ◽  
Shaimaa Elrkbwey ◽  
...  

AIM: The purpose of this study was to verify the effect of a resistance training program for 8 weeks on IGF1, gene expression, and physical performance in male student-athletes. METHODS: The population of this study was 20 male students divided to two equal groups. The parameters estimated were IGF1, gene expression, and muscle strength testing. Blood was drawn to verify the concentration of the variables, using kits and Elisa method in addition to the PCR technique. RESULTS: The results revealed that a significant increase in IGF1, gene expression was different between students. Furthermore, muscle strength testing revealed significant changes. CONCLUSION: The results suggested that resistance training program may impact fitness and muscle strength as well the anabolic activity through IGF1 increase accompanied by varied gene expressions.

2009 ◽  
Vol 40 (3) ◽  
pp. 396-403 ◽  
Author(s):  
Heleen H. Hamberg-van Reenen ◽  
Bart Visser ◽  
Allard J. van der Beek ◽  
Birgitte M. Blatter ◽  
Jaap H. van Dieën ◽  
...  

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 10027-10027
Author(s):  
Matthew R Krull ◽  
Carrie R. Howell ◽  
Robyn Partin, MS ◽  
Ginger Carney ◽  
Daniel A. Mulrooney ◽  
...  

10027 Background: Muscle weakness, low lean muscle mass and poor physical performance are prevalent among adult survivors of childhood cancer. We evaluated the effects of resistance training with and without protein supplementation on lean muscle mass, and muscle strength among childhood cancer survivors. Methods: This double-blind placebo-controlled trial enrolled survivors aged ≥18 to < 45 years. Participants were randomized to resistance training with daily protein supplement (21g protein/day, 90kcal) (RT+S) or resistance training with placebo (sucrose, 90kcal) (RT+P). Both groups received educational materials, access to a local fitness center and a tailored resistance training program with tapered supervision. Lean muscle mass and muscle strength were assessed at baseline and 24 weeks, using dual x-ray absorptiometry and dynamometer testing respectively. Mean changes were compared within and between groups. Results: Of 93 participants randomized, 57 completed the 24-week intervention (24 in RT+S, 33 in RT+P). The mean age was 33.1 (SD 7.0), 67% were white and 47% female. The RT+S group had a significant increase in lean body mass (1.05 kg [SD 2.34], p = 0.04), while the RT+P group did not (0.13 kg [SD 2.19], p = 0.74). Mean change in handgrip strength also improved in the RT+S group (1.98 [SD 4.30], p = 0.03); change approached significance in the RT+P group (1.49 [SD 4.60], p = 0.07). All survivors significantly improved their strength over time (Table) as measured by one max repetition test at baseline and follow-up. Conclusions: Preliminary findings indicate that a supervised resistance training program among adult survivors of childhood cancer that includes protein supplementation is feasible and may increase total lean body mass and muscle strength. Clinical trial information: NCT02501460. [Table: see text]


Author(s):  
Jacopo Antonino Vitale ◽  
Matteo Bonato ◽  
Stefano Borghi ◽  
Carmelo Messina ◽  
Domenico Albano ◽  
...  

Background. The aim of this study was to evaluate the effect of a six-month home-based resistance-training program on muscle health and physical performance in healthy older subjects during the unique condition of home confinement caused by the COVID-19 pandemic. Methods. This was a randomized-controlled study that enrolled older participants that were allocated to either an experimental group performing the six-months exercise prescription (EXE) or a control group (CON). At the beginning (PRE), and after 6 months (POST), participants were assessed for muscle strength, balance, gait assessment and body composition by dual energy X-ray absorptiometry and magnetic resonance imaging. Normality distribution of data was checked with the D’Agostino and Pearson test and changes between PRE and POST were assessed by paired Student’s t-test while percentage and absolute changes between groups at POST were tested by unpaired t-test. Results. Nine participants were included for the final analysis: EXE, n = 5 (age: 66 ± 4; BMI: 27.5 ± 3.7) and CON, n = 4 (age: 71 ± 9; BMI: 24.2 ± 4.1). Significant PRE-to-POST changes were observed in the EXE group only in the chair-stand test (+19.8%, p = 0.048 and ES:1.0, moderate) and in total fat mass (+5.0%, p = 0.035 and ES:1.4, large) with no between-group differences. Moreover, EXE had significantly higher absolute thigh CSA values than CON at POST (14.138 ± 2977 vs. 9039 ± 1015, p = 0.0178, ES = 1.7). No other within- and between-group differences were detected. Conclusions. The home-based resistance-training program during the lockdown period, caused by the COVID-19 outbreak, determined only within-group improvement in lower limb muscle strength but not in muscle mass and composition in older subjects. Home confinement may partially explain the increase in total body fat due to a reduced daily PA regime and altered diet pattern.


2002 ◽  
Vol 16 (2) ◽  
pp. 220 ◽  
Author(s):  
Ericka Sant’Ana Federici Trancoso ◽  
Paulo de Tarso Veras Farinatti

O treinamento da força (TF) tem se revelado eficaz em idosos frágeis. Contudo, dúvidas persistem sobre a resposta ao treinamento em idosos com nível de independência funcional elevado. O objetivo do estudo foi observar os efeitos de 12 semanas de TF sobre a força muscular em mulheres idosas funcionalmente autônomas, mas sem experiência prévia com este tipo de treinamento. Trinta e cinco mulheres com 62 a 77 anos de idade passaram por anamnese e teste de esforço com ECG. Uma voluntária foi excluída por utilizar marcapasso, outras duas exibiram sinais de isquemia, seis não compareceram ao teste de esforço e sete abandonaram o TF por razões .diversas. A casuística contou com 19 indivíduos (idade = 69 ± 5 anos). Foram realizadas, duas vezes por semana durante 12 semanas, duas séries de 10 repetições máximas (RM) em exercícios para membros inferiores (“leg-press”) e superiores (supino reto). As médias semanais do volume de treinamento foram comparadas através de ANOVA para medidas repetidas (p < 0,05). Os resultados indicaram tendência à melhoria da força durante o período observado, nos dois exercícios, da ordem de 58% para o “leg-press” e 61% para o supino. O ganho de força evoluiu rapidamente nas primeiras quatro semanas, tendendo a estabilizar-se nas semanas finais. Conclui-se que o TF pode apresentar resultados positivos em idosas com bom nível de independência funcional. A possibilidade destes ganhos ocorrerem em treinamentos de prazo mais longo, todavia, revela-se duvidosa


2021 ◽  
Author(s):  
Nicola Theis ◽  
Marika Noorkoiv ◽  
Grace Lavelle ◽  
Jennifer Ryan

Abstract Objective The aim of the study was to examine the variability in plantar-flexor muscle strength changes after progressive resistance training for adolescents with cerebral palsy (CP) and to identify baseline variables associated with change in muscle strength. Methods Thirty-three adolescents with CP were randomized to a 10-week progressive resistance training program as part of a randomized controlled trial (STAR trial). The associations between muscle strength at 10 weeks (n = 30 adolescents) and 22 weeks (n = 28 adolescents) and biomechanical and neuromuscular baseline characteristics, motor function, and fidelity to the program were examined with multivariable linear regression. Conclusion Assessing levels of muscle activation may be able to identify responders to a progressive resistance training program for adolescents with CP. These findings are a first step toward developing tools that can inform decision making in the clinical setting. Impact Due to the heterogenous nature of CP, it is challenging to assess the efficacy of strength training programs in individuals with CP and to understand the variability in outcomes among participants. This study provides a better understanding of the factors that predict response to an exercise program so that resistance training can be directed to those who will potentially benefit from it. Lay Summary There is wide variability in how well young people with CP respond to resistance training. If you are a young person with CP, your physical therapist can measure the amount of your gastrocnemius muscle activity to get an indication of how well you will respond.


2001 ◽  
Vol 13 (4) ◽  
pp. 357-372 ◽  
Author(s):  
Eliahu Sadres ◽  
Alon Eliakim ◽  
Naama Constantini ◽  
Ronnie Lidor ◽  
Bareket Falk

The purpose of this study was to examine the effect of 2 school years (21 months) of a twice-weekly resistance training program on stature, muscle strength, and self-concept among prepubertal boys. The experimental group (E, n = 27) aged 9.2 ± 0.3 yrs, participated in progressive resistance training, while the control group (C, n = 22) aged 9.4 ± 0.3 yrs, participated in standard physical education classes (as advised by the Ministry of Education). Training sessions included 1–4 sets of 3–6 exercises, with 5–30 repetitions/set. The load ranged between 30% and 70% 1RM. No differences were observed in the gain in body height between groups. Muscle strength increased significantly more in E (e.g., knee extensors: 0.51 ± 0.13 to 0.77 ± 0.16 kg/kg body mass), compared with C (0.34 ± 0.12 to 0.54 ± 0.11 kg/kg body mass). One minor injury was reported throughout the study. Initial scores of self-concept were high in both groups, with no training effect. The results demonstrate that among prepubertal boys, a twice-weekly low-to-moderate-intensity resistance training program over a period of 2 school years (21 months) can result in enhancement in muscle strength with no detrimental effect on growth.


2019 ◽  
Vol 35 (2) ◽  
pp. 355-363 ◽  
Author(s):  
Johny N. Almeida ◽  
Wagner L. Prado ◽  
Caio M. Terra ◽  
Matheus G. Oliveira ◽  
Renato A. Garcia ◽  
...  

2009 ◽  
Vol 41 ◽  
pp. 130
Author(s):  
Juan M. Cortell-Tormo ◽  
José A. Pérez-Turpin ◽  
Pablo Tercedor-Sánchez ◽  
Alfonso Jiménez ◽  
Roberto Cejuela-Anta

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