scholarly journals Dose and drug changes in chronic lymphocytic leukemia cell response in�vitro: A comparison of standard therapy regimens with two novel cyclin‑dependent kinase inhibitors

2019 ◽  
Author(s):  
Małgorzata Kubczak ◽  
Aleksandra Szustka ◽  
Jerzy Błoński ◽  
Tomaš Guck� ◽  
Małgorzata Misiewicz ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Cell Response ◽  
Standard Therapy ◽  
Kinase Inhibitors ◽  
Leukemia Cell ◽  
Lymphocytic Leukemia ◽  
Chronic Lymphocytic Leukemia Cell ◽  
Cyclin Dependent Kinase ◽  
Lymphocytic Leukemia Cell

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia

Blood ◽  
2014 ◽  
Vol 123 (23) ◽  
pp. 3607-3617 ◽  
Author(s):  
Elisabeth Walsby ◽  
Andrea Buggins ◽  
Stephen Devereux ◽  
Ceri Jones ◽  
Guy Pratt ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Critical Role ◽  
Leukemia Cell ◽  
Lymphocytic Leukemia ◽  
Chronic Lymphocytic Leukemia Cell ◽  
Cell Phenotype ◽  
Lymphocyte Migration ◽  
Lymphocytic Leukemia Cell ◽  
And Behavior

Key Points We have developed a novel in vitro system to model how shear force and transient interaction with endothelial cells alter chronic lymphocytic leukemia cell phenotype and behavior. We have used our model to investigate chronic lymphocytic leukemia cell migration and have determined the critical role for integrin α4β1 in this process.

scholarly journals Characterization of a New Chronic Lymphocytic Leukemia Cell Line for Mechanistic In Vitro and In Vivo Studies Relevant to Disease

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e76607 ◽  
Author(s):  
Erin Hertlein ◽  
Kyle A. Beckwith ◽  
Gerard Lozanski ◽  
Timothy L. Chen ◽  
William H. Towns ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Leukemia Cell ◽  
Lymphocytic Leukemia ◽  
In Vivo Studies ◽  
Leukemia Cell Line ◽  
Chronic Lymphocytic Leukemia Cell ◽  
Lymphocytic Leukemia Cell

scholarly journals Matrix Metalloproteinase-9 Is Involved in Chronic Lymphocytic Leukemia Cell Response to Fludarabine and Arsenic Trioxide

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99993 ◽  
Author(s):  
Irene Amigo-Jiménez ◽  
Elvira Bailón ◽  
Estefanía Ugarte-Berzal ◽  
Noemí Aguilera-Montilla ◽  
José A. García-Marco ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Matrix Metalloproteinase ◽  
Arsenic Trioxide ◽  
Cell Response ◽  
Leukemia Cell ◽  
Matrix Metalloproteinase 9 ◽  
Lymphocytic Leukemia ◽  
Chronic Lymphocytic Leukemia Cell ◽  
Lymphocytic Leukemia Cell ◽  
Metalloproteinase 9
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