Recombinant Antibodies and Their Potential Applications in Veterinary Medicine

2019 ◽  
Vol 13 (1) ◽  
pp. 1-3
Author(s):  
Amit Kumar Verma ◽  
Desh Deepak ◽  
Arbind Singh ◽  
Vipul Thakur
Author(s):  
Lorena Bustamante-Córdova ◽  
Edgar A. Melgoza-González ◽  
Jesús Hernández

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Solène Niederlender ◽  
Jean-Jacques Fontaine ◽  
Grégory Karadjian

AbstractAptamers are small nucleic acids that fold in a three-dimensional conformation allowing them to bind specifically to a target. This target can be an organic molecule, free or carried in cells or tissues, or inorganic components, such as metal ions. Analogous to monoclonal antibodies, aptamers however have certain advantages over the latter: e.g., high specificity for their target, no to low immunogenicity and easy in vitro selection. Since their discovery more than 30 years ago, aptamers have led to various applications, although mainly restricted to basic research. This work reviews the applications of aptamers in veterinary science to date. First, we present aptamers, how they are selected and their properties, then we give examples of applications in food and environmental safety, as well as in diagnosis and medical treatment in the field of veterinary medicine. Because examples of applications in veterinary medicine are scarce, we explore the potential avenues for future applications based on discoveries made in human medicine. Aptamers may offer new possibilities for veterinarians to diagnose certain diseases—particularly infectious diseases—more rapidly or “at the patient’s bedside”. All the examples highlight the growing interest in aptamers and the premises of a potential market. Aptamers may benefit animals as well as their owners, breeders and even public health in a “One Health” approach.


2011 ◽  
Vol 47 (2) ◽  
pp. 73-82 ◽  
Author(s):  
Michael Higginbotham ◽  
Donald Levesque

The endoscope was first developed over 200 yr ago. Endoscopy has since been applied to many disciplines of medicine. Its application to the nervous system was initially slow and not widely accepted and mainly involved the biopsy of tumors and the treatment of hydrocephalus. Several reasons for neuroendoscopy's limited use include inadequate endoscope technology, high skill level required, the advent of the surgical microscope, and the development of other treatments such as ventricular shunting. Over the past 50 yr, improvements in optical glass lenses, fiber optics, and electrical circuitry has led to better equipment and a revival of neuroendoscopy. Neuroendoscopy is now used in many diseases in human medicine including hydrocephalus, neoplasia, and intracranial cysts. This review presents the history of neuroendoscopy, the equipment and technology used, and the possible translation of techniques currently used in human medicine to veterinary medicine.


2012 ◽  
Vol 51 (No. 5) ◽  
pp. 212-223 ◽  
Author(s):  
R. Pribylova ◽  
I. Pavlik ◽  
M. Bartos

Genetically modified organisms (GMO) become a real constituent of our lives and nowadays, they are commonly introduced into the food chain of people and animals in some states. Among higher organisms, plants are used above all for genetic modifications; potatoes are a suitable model plants for this purpose. Nowadays, a number of various genetic modifications of potato plants are available, particularly those with increased resistance to biological agents and factors of the external environment or with improved nutritional value. Plants that produce proteins of the immune system of man or animals or substances that may be used as vaccines in human or veterinary medicine are highly important. Modified potato plants that produce biomaterials for potential applications in the industry are a significant category.


2008 ◽  
Vol 233 (10) ◽  
pp. 1564-1574 ◽  
Author(s):  
Chick W. Weisse ◽  
Allyson C. Berent ◽  
Kimberly L. Todd ◽  
Jeffrey A. Solomon

2021 ◽  
Vol 8 (2) ◽  
pp. 20
Author(s):  
Andrea Marchegiani ◽  
Andrea Spaterna ◽  
Matteo Cerquetella

The purpose of this review is to determine the state of the art of the mode of action and potential applications of fluorescence photobiomodulation in veterinary medicine. After a summary of the assets that have led the translation of such light-based therapies from bench side into clinical use, recent advances in canine dermatology using this brand-new approach are presented, and future scenarios where this type of care may provide benefits over the current standard care are highlighted.


2004 ◽  
Vol 56 (10) ◽  
pp. 1467-1480 ◽  
Author(s):  
Sevda Şenel ◽  
Susan J McClure

2020 ◽  
Vol 21 (14) ◽  
pp. 5122 ◽  
Author(s):  
Dimitri Leonid Lindenwald ◽  
Bernd Lepenies

C-type lectins (CTLs), a superfamily of glycan-binding receptors, play a pivotal role in the host defense against pathogens and the maintenance of immune homeostasis of higher animals and humans. CTLs in innate immunity serve as pattern recognition receptors and often bind to glycan structures in damage- and pathogen-associated molecular patterns. While CTLs are found throughout the whole animal kingdom, their ligand specificities and downstream signaling have mainly been studied in humans and in model organisms such as mice. In this review, recent advancements in CTL research in veterinary species as well as potential applications of CTL targeting in veterinary medicine are outlined.


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