scholarly journals SGLT-2 inhibitors are potential game-changers (for more than diabetes)

2021 ◽  
Vol 88 (11) ◽  
pp. 588-589
Author(s):  
Brian F. Mandell
Keyword(s):  
Potential Game

scholarly journals The Evolution of Networks and Local Public Good Provision: A Potential Approach

Games ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 55
Author(s):  
Markus Kinateder ◽  
Luca Paolo Merlino
Keyword(s):  
Public Good ◽  
Nash Equilibria ◽  
Potential Game ◽  
Public Good Provision ◽  
Local Public Good ◽  
Steady State Distribution ◽  
State Distribution ◽  
Long Run ◽  
Split Graphs ◽  
Good Provision

In this paper, we propose a game in which each player decides with whom to establish a costly connection and how much local public good is provided when benefits are shared among neighbors. We show that, when agents are homogeneous, Nash equilibrium networks are nested split graphs. Additionally, we show that the game is a potential game, even when we introduce heterogeneity along several dimensions. Using this result, we introduce stochastic best reply dynamics and show that this admits a unique and stationary steady state distribution expressed in terms of the potential function of the game. Hence, even if the set of Nash equilibria is potentially very large, the long run predictions are sharp.

scholarly journals Development of robust isothermal RNA amplification assay for lab-free testing of RNA viruses

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Radhika Biyani ◽  
Kirti Sharma ◽  
Kenji Kojima ◽  
Madhu Biyani ◽  
Vishnu Sharma ◽  
...  
Keyword(s):  
Rna Virus ◽  
Point Of Care ◽  
Human Saliva ◽  
Nucleic Acid Amplification ◽  
Potential Game ◽  
One Pot ◽  
Viral Loads ◽  
Copy Numbers ◽  
Amplification Assay ◽  
Primary Focus

AbstractSimple tests of infectiousness that return results in minutes and directly from samples even with low viral loads could be a potential game-changer in the fight against COVID-19. Here, we describe an improved isothermal nucleic acid amplification assay, termed the RICCA (RNA Isothermal Co-assisted and Coupled Amplification) reaction, that consists of a simple one-pot format of ‘sample-in and result-out’ with a primary focus on the detection of low copy numbers of RNA virus directly from saliva without the need for laboratory processing. We demonstrate our assay by detecting 16S rRNA directly from E. coli cells with a sensitivity as low as 8 CFU/μL and RNA fragments from a synthetic template of SARS-CoV-2 with a sensitivity as low as 1740 copies/μL. We further demonstrate the applicability of our assay for real-time testing at the point of care by designing a closed format for paper-based lateral flow assay and detecting heat-inactivated SARS-COV-2 virus in human saliva at concentrations ranging from 28,000 to 2.8 copies/μL with a total assay time of 15–30 min.

scholarly journals Multipath Wireless Network Coding: A Scheduling Constraint in Game Perspective

2021 ◽  
pp. 105-109
Author(s):  
Dr. D. Chitra ◽  
K. Ilakkiya
Keyword(s):  
Wireless Networks ◽  
Network Coding ◽  
Potential Game ◽  
Level Control ◽  
Link Capacity ◽  
Space Extension ◽  
Wireless Network Coding ◽  
Traffic Matrix ◽  
Control Scheme ◽  
User Actions

This paper considers wireless networks in which various paths are obtainable involving each source and destination. It is allowing each source to tear traffic among all of its existing paths, and it may conquer the lowest achievable number of transmissions per unit time to sustain a prearranged traffic matrix. Traffic bound in contradictory instructions in excess of two wireless hops can utilize the “reverse carpooling” advantage of network coding in order to decrease the number of transmissions used. These call such coded hops “hyper-links.” With the overturn carpooling procedure, longer paths might be cheaper than shorter ones. However, convenient is an irregular situation among sources. The network coding advantage is realized only if there is traffic in both directions of a shared path. This project regard as the problem of routing amid network coding by egotistic agents (the sources) as a potential game and develop a method of state-space extension in which extra agents (the hyper-links) decouple sources’ choices from each other by declaring a hyper-link capacity, allowing sources to split their traffic selfishly in a distributed fashion, and then altering the hyper-link capacity based on user actions. Furthermore, each hyper-link has a scheduling constraint in stipulations of the maximum number of transmissions authorized per unit time. Finally these project show that our two-level control scheme is established and verify our investigative insights by simulation.

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