UTSE: A Game Engine-Based Simulation Environemnt for Agent

2014 ◽  
Vol 496-500 ◽  
pp. 2142-2145 ◽  
Author(s):  
Ji Wen Hu ◽  
Chao Feng ◽  
Yi Liu ◽  
Ri Yi Zhu
Keyword(s):  
Computer Games ◽  
High Fidelity ◽  
Simulation Environment ◽  
Game Engine ◽  
Core Component ◽  
Realistic Simulation ◽  
The Core ◽  
Modern Computer ◽  
Agent Simulation ◽  
Simulation Environments

The development of realistic simulation environments is an expensive and time-consuming enterprise. Game Engine is the core component of modern computer games and it provides fundamental functions for games. In this paper, in order to save time and money, game engine is used as platform to develop simulation environment for agents. An Unreal Tournament-Based Simulation Environment (UTSE) for agent simulation is proposed. The reasons for selecting Unreal Engine as the start point of developing our simulation environment are presented. The implementation details of UTSE are also expatiated. And finally, a simple case is given to demonstrate the effectiveness of UTSE to rapidly produce game engine-based high fidelity simulations.

Partitioned Model vs Parallelized Solver

2011 ◽  
Author(s):  
Lars Mikelsons ◽  
Nils Menager ◽  
Dieter Schramm
Keyword(s):  
Point Of View ◽  
Simulation Environment ◽  
Multicore Processor ◽  
Multicore Architecture ◽  
Time Constants ◽  
Modern Computer ◽  
Significant Difference ◽  
Full Power ◽  
Simulation Point ◽  
Simulation Environments

Nowadays, engineers still search for more efficient methods in order to decrease simulation times. However, most simulation environments do not use the full power provided by modern PCs. Even though every modern computer is equipped with a multicore processor, only very few simulation environments use more than one core for simulations. There are various possibilities to parallelize simulations. One approach is to partition the model into several submodels. Using adequate solvers for each submodel can result in lower computation times, especially if there is a significant difference in the time constants of the submodels. Other approaches are based on parallelization of the ODE solver. For example, it is possible to parallelize the linear algebra methods inside the solver. Parallelization of the solver itself is another way to use the multicore architecture. From the modeling and simulation point of view, the latter approach is more interesting. Consequently, the question is whether it is beneficial to partition the model or to use a parallelized solver. In this paper this question is answered at least for an example system. However, the more efficient approach may not be the better approach for the usage inside a simulation environment. Therefore, it is discussed which approach can be automated and integrated easier into a simulation environment.

scholarly journals Avolition as the core negative symptom in schizophrenia: relevance to pharmacological treatment development

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Gregory P. Strauss ◽  
Lisa A. Bartolomeo ◽  
Philip D. Harvey
Keyword(s):  
Negative Symptom ◽  
Negative Symptoms ◽  
Clinical Trial Design ◽  
Core Component ◽  
Treatment Target ◽  
Global Improvement ◽  
Treatment Development ◽  
The Core ◽  
Current Review ◽  
Symptom Domains

AbstractNegative symptoms have long been considered a core component of schizophrenia. Modern conceptualizations of the structure of negative symptoms posit that there are at least two broad dimensions (motivation and pleasure and diminished expression) or perhaps five separable domains (avolition, anhedonia, asociality, blunted affect, alogia). The current review synthesizes a body of emerging research indicating that avolition may have a special place among these dimensions, as it is generally associated with poorer outcomes and may have distinct neurobiological mechanisms. Network analytic findings also indicate that avolition is highly central and interconnected with the other negative symptom domains in schizophrenia, and successfully remediating avolition results in global improvement in the entire constellation of negative symptoms. Avolition may therefore reflect the most critical treatment target within the negative symptom construct. Implications for targeted treatment development and clinical trial design are discussed.

scholarly journals Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Anastasiia Samsonova ◽  
Krystel El Hage ◽  
Bénédicte Desforges ◽  
Vandana Joshi ◽  
Marie-Jeanne Clément ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Cold Shock ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Rna Binding Protein ◽  
Large Set ◽  
Core Component ◽  
The Core ◽  
Cold Shock Domain ◽  
Global Translation

AbstractThe RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression. Although Lin28 blocks let-7 microRNA maturation, Lin28 also binds to a large set of cytoplasmic mRNAs directly. However, how Lin28 regulates the processing of many mRNAs to reprogram global translation remains unknown. We show here, using a structural and cellular approach, a mixing of Lin28 with YB-1 (YBX1) in the presence of mRNA owing to their cold-shock domain, a conserved β-barrel structure that binds to ssRNA cooperatively. In contrast, the other RNA binding-proteins without cold-shock domains tested, HuR, G3BP-1, FUS and LARP-6, did not mix with YB-1. Given that YB-1 is the core component of dormant mRNPs, a model in which Lin28 gains access to mRNPs through its co-association with YB-1 to mRNA may provide a means for Lin28 to reprogram translation. We anticipate that the translational plasticity provided by mRNPs may contribute to Lin28 functions in development and adaptation of cancer cells to an adverse environment.

scholarly journals Enhancing Postgraduate Learning and Teaching: Postgraduate Summer School in Dairy Science

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Pietro Celi ◽  
Gianfranco Gabai ◽  
Massimo Morgante ◽  
Luigi Gallo
Keyword(s):  
Summer School ◽  
Research Collaboration ◽  
Learning Experience ◽  
Scientific Investigation ◽  
Core Component ◽  
Learning And Teaching ◽  
Transferable Skills ◽  
The Core ◽  
Dairy Science ◽  
The University

Dairy science is a multidisciplinary area of scientific investigation and Ph.D. students aiming to do research in the field of animal and/or veterinary sciences must be aware of this. Ph.D. students often have vast spectra of research interests, and it is quite challenging to satisfy the expectation of all of them. The aim of this study was to establish an international Ph.D. training program based on research collaboration between the University of Sydney and the University of Padova. The core component of this program was a two-week Postgraduate Summer School in Dairy Science, which was held at the University of Padova, for Ph.D. students of both universities. Therefore, we designed a program that encompassed seminars, workshops, laboratory practical sessions, and farm visits. Participants were surveyed using a written questionnaire. Overall, participants have uniformly praised the Summer School calling it a rewarding and valuable learning experience. The Ph.D. Summer School in Dairy Science provided its participants a positive learning experience, provided them the opportunity to establish an international network, and facilitated the development of transferable skills.

Architectural Design of Trusted Platform for IaaS Cloud Computing

2018 ◽  
Vol 8 (2) ◽  
pp. 47-65 ◽  
Author(s):  
Ubaidullah Alias Kashif ◽  
Zulfiqar Ali Memon ◽  
Shafaq Siddiqui ◽  
Abdul Rasheed Balouch ◽  
Rakhi Batra
Keyword(s):  
Cloud Computing ◽  
Service Provider ◽  
Architectural Design ◽  
Cloud Services ◽  
Core Component ◽  
Malicious Activity ◽  
The Core ◽  
Potential Benefits ◽  
Trusted Platform ◽  
Access Right

This article describes how the enormous potential benefits provided by the cloud services, made enterprises to show huge interest in adopting cloud computing. As the service provider has control over the entire data of an organization stored onto the cloud, a malicious activity, whether internal or external can tamper with the data and computation. This causes enterprises to lack trust in adopting services due to privacy, security and trust issues. Despite of having such issues, the consumer has no root level access right to secure and check the integrity of procured resources. To establish a trust between the consumer and the provider, it is desirable to let the consumer to check the procured platform hosted at provider side for safety and security. This article proposes an architectural design of a trusted platform for the IaaS cloud computing by the means of which the consumer can check the integrity of a guest platform. TCG's TPM is deployed and used on the consumer side as the core component of the proposed architecture and it is distributed between the service provider and the consumer.

scholarly journals Mitochondria-driven assembly of a cortical anchor for mitochondria and dynein

2017 ◽  
Vol 216 (10) ◽  
pp. 3061-3071 ◽  
Author(s):  
Lauren M. Kraft ◽  
Laura L. Lackner
Keyword(s):  
Plasma Membrane ◽  
Mitotic Spindle ◽  
Cell Cortex ◽  
Dual Function ◽  
Mitochondrial Inheritance ◽  
Cellular Functions ◽  
Core Component ◽  
Spindle Positioning ◽  
The Core ◽  
Contact Sites

Interorganelle contacts facilitate communication between organelles and impact fundamental cellular functions. In this study, we examine the assembly of the MECA (mitochondria–endoplasmic reticulum [ER]–cortex anchor), which tethers mitochondria to the ER and plasma membrane. We find that the assembly of Num1, the core component of MECA, requires mitochondria. Once assembled, Num1 clusters persistently anchor mitochondria to the cell cortex. Num1 clusters also function to anchor dynein to the plasma membrane, where dynein captures and walks along astral microtubules to help orient the mitotic spindle. We find that dynein is anchored by Num1 clusters that have been assembled by mitochondria. When mitochondrial inheritance is inhibited, Num1 clusters are not assembled in the bud, and defects in dynein-mediated spindle positioning are observed. The mitochondria-dependent assembly of a dual-function cortical anchor provides a mechanism to integrate the positioning and inheritance of the two essential organelles and expands the function of organelle contact sites.

scholarly journals Images of game and gamer in the space of literature and computer games

2020 ◽  
pp. 69-80
Author(s):  
Olga Anatol'evna Bychkova ◽  
Aleksandra Valer'evna Nikitina
Keyword(s):  
Computer Games ◽  
Russian Literature ◽  
Literary Work ◽  
Psychological Type ◽  
Classical Literature ◽  
Modern Computer ◽  
The World ◽  
The Subject ◽  
Queen Of Spades ◽  
First Time

The subject of this research is the images of game and gamers. In the space of literary work, they are arrayed in metaphorical and often demonic raiment, receiving moral-ethical interpretation in one or another way. The problem of game and gamer in criticism was regarded by Y. Mann (“On the Concept of Game as a Literary Image”), V. V. Vinogradov (“Style of the Queen of Spades”), E. Dobin (“Ace and Queen”, A. Pushkin’s “The Queen of Spades”), R. Caillois (“Games and People”), British writer and researcher of online games R, Bartle, American scientist Nick Yee, and many others. However, juxtaposition of literature sources on the topic to the research in the field of computer games is conducted for the first time. The scientific novelty consists in the comprehensive examination of the psychological game of the gamer based on the material of Russian literature (A. S. Pushkin “The Queen of Spades”, V. V. Nabokov The Luzhin Defense”) , as well as the modern computer games practice, in which psychological type of the gamer found its realization and development in accordance with genre diversity. Even the Russian classical literature depict game as an autonomous space that encompasses the gamer, and often has devastating effect on their personality. The author also observes an important characterological trait of the gamer: the conceptual, “literal” perception of the world, which is based on the reception of visual images of the world against verbal. Therefore, the Russian literature alongside the research practice of modern videogames from different angles approach examination of the images of “game and gamer”, cognize the factors and consequences of the problems that emerge in this object field, as well as seek for their solution. The data acquired in the course of the conducted comparative analysis is mutually enriching.

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