Clinical Significance of Aspirin on Blood Flow through Stenotic Blood Vessels

Author(s):  
Sapna Ratan Shah

In this present study a two-phase model for the influence of aspirin on peripheral layer viscosity for physiological characteristics of blood flow through stenosed blood vessels using Casson’s fluid model has been obtained. Flow of blood with axially non-symmetric but radially symmetric stenosis geometry is considered. The non-linear pressure equations have been solved with help of boundary conditions and the results are displayed graphically for different flow characteristics. It was found that the resistance to flow decreases as stenosis shape parameter increases whereas the resistance to flow increases with increasing values of stenosis length, stenosis size and peripheral layer viscosity. The effects of stenosis severity and wall shear stress are discussed in the present computational analysis. Comparisons between the measured and computed peripheral layer viscosity profiles are favourable to the solutions. As a result it can be concluded that a regular dose of Asprin decreases the blood viscosity by diluting the blood of diabetic patients which ultimately decreases the blood pressure. For the validation of the numerical model, the computation results are compared with the experimental data and results from published literature.

2013 ◽  
Vol 10 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Amit Medhavi

The present study concerns with the effects of the hematocrit and the peripheral layer on blood flow characteristics due to the presence of a bell shaped stenosis in arteries. To account for the hematocrit and the peripheral layer, the flowing blood has been represented by a two-layered macroscopic two-phase (i.e., a suspension of red cells in plasma) model. The expressions for the flow characteristics, namely, the velocity profiles, the flow rate, the impedance, the wall shear stress in the stenotic region and the shear stress at the stenosis throat have been derived. The quantitative effects of the hematocrit and the peripheral layer on these flow characteristics have been displayed graphically and discussed briefly.


Author(s):  
Sapna Ratan Shah ◽  
S. U. Siddiqui

This study focuses on the behavior of blood flow through diseased artery in the presence of porous effects. The laminar, incompressible, fully developed, non-Newtonian in an artery having axially non-symmetric but radially symmetric stenosis is numerically studied. Here blood is represented as Herschel-Bulkley fluid model and flow model is shown by the Navier-Stokes and the continuity equations. Using appropriate boundary conditions, numerical expression for volumetric flow rate, pressure drop and wall shear stress have been derived. The expressions are computed numerically and results are presented graphically. The effects of porous parameter on wall shear stress, stenosis length, stenosis size and stenosis shape parameter are discussed. The wall shear stress increases as the porous parameter, stenosis size and stenosis length increases, but as the stenosis shape parameter increases, the wall shear stress decreases. The work shows that the results obtained from the porous wall model are significantly different from those obtained by the rigid wall model.


2014 ◽  
Vol 11 (1-2) ◽  
pp. 39-45
Author(s):  
Rupesh K. Srivastav ◽  
V. P. Srivastava

The present investigation concerns the fluid mechanical study on the effects of the permeability of the wall through an axisymmetric stenosis in an artery assuming that the flowing blood is represented by a two-fluid model. The expressions for the blood flow characteristics, the impedance, the wall shear stress distribution in the stenotic region and the shearing stress at the stenosis throat have been derived. Results for the effects of permeability as well as of the peripheral layer on these blood flow characteristics are quantified through numerical computations and presented graphically and discussed comparatively to validate the applicability of the present model.


2013 ◽  
Vol 10 (1) ◽  
pp. 1-9
Author(s):  
Amit Medhavi

The present paper concerns with the fluid mechanical study on the effects of the permeability of the wall through an overlapping stenosis in an artery assuming that the flowing blood is represented by a macroscopic two-phase model. The expressions for the blood flow characteristics, the impedance, the wall shear stress distribution in the stenotic region, shearing stress at the stenosis throats and at the stenosis critical height have been derived. Results for the effects of permeability as well as of hematocrit on these blood flow characteristics are shown graphically and discussed briefly.


2015 ◽  
Vol 08 (04) ◽  
pp. 1550045 ◽  
Author(s):  
Noreen Sher Akbar

In this paper, the blood flow through a tapered artery with a stenosis by considering axially non-symmetric but radially symmetric mild stenosis on blood flow characteristics is analyzed, assuming the flow is steady and blood is treated as Williamson fluid. The effects of mixed convection heat and mass transfer are also carried out. Perturbation solutions have been calculated for velocity, temperature, concentration, resistance impedance, wall shear stress and shearing stress at the stenosis throat. The graphical results of different types of tapered arteries (i.e. converging tapering, diverging tapering, non-tapered artery) have been examined for different parameters of interest. Streamlines have been plotted at the end of the paper.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Obaid Ullah Mehmood ◽  
Sehrish Bibi ◽  
Dzuliana F. Jamil ◽  
Salah Uddin ◽  
Rozaini Roslan ◽  
...  

AbstractThe current work analyzes the effects of concentric ballooned catheterization and heat transfer on the hybrid nano blood flow through diseased arterial segment having both stenosis and aneurysm along its boundary. A fractional second-grade fluid model is considered which describes the non-Newtonian characteristics of the blood. Governing equations are linearized under mild stenosis and mild aneurysm assumptions. Precise articulations for various important flow characteristics such as heat transfer, hemodynamic velocity, wall shear stress, and resistance impedance are attained. Graphical portrayals for the impact of the significant parameters on the flow attributes have been devised. The streamlines of blood flow have been examined as well. The present finding is useful for drug conveyance system and biomedicines.


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