Evaluation: Specific Energy Deposition from 252Cf-Sol-Gel Glass in Brain Interstitial Implants

2008 ◽  
Vol 396-398 ◽  
pp. 721-724 ◽  
Author(s):  
B.M. Mendes ◽  
T.P.R. Campos
Keyword(s):  
Specific Energy ◽  
Energy Deposition ◽  
Sol Gel ◽  
Computer Code ◽  
Source Distance ◽  
Neutron Brachytherapy ◽  
Deposition Dose ◽  
Tissue Sparing ◽  
Tumor Implant ◽  
Deep Brain

Neutron brachytherapy show better results than conventional photon therapy for radioresistant tumors with hypoxic regions. Herein a comparative radiodosimetric analysis is presented considering 125I photon emitter seeds, often applied to brachytherapy, and a proposed Sol-Gel glass, synthesized with incorporated 252Cf neutron emitter, on a brain tumor implant. The proposition is to verify the viability of applying this bioceramic material. The methodology is based on the investigation of the specific energy deposition (dose) from 252Cf-Glass in deep brain interstitial implants through a stochastic computer code (MCNP5) and comparison with 125I seed’s energy deposition. 252Cf-Glass show dose per transition values higher than 125I seed’s set. RBE-isodose curves show a faster decrease of dose with the source distance increasing which can improve healthy tissue sparing.

Measurement of the Total Range and Specific Energy Deposition of a Beam of Uranium Ions in Porous Carbon Targets

Atomic Energy ◽  
2004 ◽  
Vol 96 (4) ◽  
pp. 275-281 ◽  
Author(s):  
V. V. Vatulin ◽  
A. V. Kunin ◽  
A. A. Golubev ◽  
V. E. Luk'yashin ◽  
V. I. Turtikov ◽  
...  
Keyword(s):  
Specific Energy ◽  
Porous Carbon ◽  
Energy Deposition ◽  
Uranium Ions ◽  
Total Range

scholarly journals Internal microdosimetry of alpha-emitting radionuclides

2019 ◽  
Vol 59 (1) ◽  
pp. 29-62 ◽  
Author(s):  
Werner Hofmann ◽  
Wei Bo Li ◽  
Werner Friedland ◽  
Brian W. Miller ◽  
Balázs Madas ◽  
...  
Keyword(s):  
Alpha Particle ◽  
Specific Energy ◽  
Energy Deposition ◽  
Biological Effects ◽  
Track Length ◽  
Target Cells ◽  
Track Structure ◽  
Level Energy ◽  
Cell Nuclei ◽  
Energy Distributions

AbstractAt the tissue level, energy deposition in cells is determined by the microdistribution of alpha-emitting radionuclides in relation to sensitive target cells. Furthermore, the highly localized energy deposition of alpha particle tracks and the limited range of alpha particles in tissue produce a highly inhomogeneous energy deposition in traversed cell nuclei. Thus, energy deposition in cell nuclei in a given tissue is characterized by the probability of alpha particle hits and, in the case of a hit, by the energy deposited there. In classical microdosimetry, the randomness of energy deposition in cellular sites is described by a stochastic quantity, the specific energy, which approximates the macroscopic dose for a sufficiently large number of energy deposition events. Typical examples of the alpha-emitting radionuclides in internal microdosimetry are radon progeny and plutonium in the lungs, plutonium and americium in bones, and radium in targeted radionuclide therapy. Several microdosimetric approaches have been proposed to relate specific energy distributions to radiobiological effects, such as hit-related concepts, LET and track length-based models, effect-specific interpretations of specific energy distributions, such as the dual radiation action theory or the hit-size effectiveness function, and finally track structure models. Since microdosimetry characterizes only the initial step of energy deposition, microdosimetric concepts are most successful in exposure situations where biological effects are dominated by energy deposition, but not by subsequently operating biological mechanisms. Indeed, the simulation of the combined action of physical and biological factors may eventually require the application of track structure models at the nanometer scale.

scholarly journals Scaling of pulsed nanosecond capillary plasmas at different specific energy deposition

2020 ◽  
Vol 29 (12) ◽  
pp. 125006
Author(s):  
Yifei Zhu ◽  
Svetlana M Starikovskaia ◽  
Natalia Yu Babaeva ◽  
Mark J Kushner
Keyword(s):  
Specific Energy ◽  
Energy Deposition

scholarly journals Ion-Irradiation-Induced Densification of Zirconia Sol -Gel Thin Films

1993 ◽  
Vol 316 ◽  
Author(s):  
Timothy E. Levine ◽  
Emmanuel P. Giannelis ◽  
Padma Kodali ◽  
Joseph Tesmer ◽  
Michael Nastasi ◽  
...  
Keyword(s):  
Nuclear Energy ◽  
Energy Deposition ◽  
Rutherford Backscattering Spectrometry ◽  
Ion Irradiation ◽  
Sol Gel ◽  
Electronic Energy ◽  
Target Atom ◽  
Recoil Energy ◽  
Ion Energies ◽  
Sol Gel Films

ABSTRACTWe have investigated the densification behavior of sol-gel zirconia films resulting from ion irradiation. Three sets of films were implanted with neon, krypton, or xenon. The ion energies were chosen to yield approximately constant energy loss through the film and the doses were chosen to yield similar nuclear energy deposition. Ion irradiation of the sol-gel films resulted in carbon and hydrogen loss as indicated by Rutherford backscattering spectrometry and forward recoil energy spectroscopy. Although the densification was hypothesized to result from target atom displacement, the observed densification exhibits a stronger dependence on electronic energy deposition.

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