Porous Bioceramic Made from Cow Bone Powder Mixed Calcium Phosphate Glass: Clinical Trial

2020 ◽  
Vol 990 ◽  
pp. 81-85
Author(s):  
Sittiporn Punyanitya ◽  
Rungsarit Koonawoot ◽  
Phanlob Chankachang ◽  
Sakdiphon Thiensem ◽  
Anirut Raksujarit ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Phosphate Glass ◽  
Laboratory Animals ◽  
Bovine Bone ◽  
Glass Composites ◽  
Bone Powder ◽  
Porous Bioceramic ◽  
Bone Calcium ◽  
Cow Bone

Our objective is invention of new medical products in Thailand by Thai scientists, for human bone substitute, from cow bone. In the previous research experiments, the cow bone-calcium phosphate glass composites had adequate scientific properties to be used as medical objects including, 95% of principal molecules were inorganic hydroxyapatite, no contaminating dangerous heavy metal over standard limits (cadmium,arsenic,mercury,lead), high vertical compressive strength (more than 400 kg/cm2), and no adverse reactions inside the laboratory animals. In this research, we made cranialfixator buttons from bovine bone-calcium phosphate glass composites, intended for neurosurgical skull closure, tested in 10 patients and follow up for at least 6 months. The results revealed that our inventions have easily performance, really effectiveness,and entirely non-complications.

Fabrication and Characterization of Porous Bioceramic Made from Bovine Bone Powder Mixed Calcium Phosphate Glass

2019 ◽  
Vol 803 ◽  
pp. 187-191 ◽  
Author(s):  
Sittiporn Punyanitya ◽  
Sakdiphon Thiansem ◽  
Anirut Raksujarit ◽  
Phanlob Chankachang ◽  
Tiwasawat Sirisoam ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Phosphate Glass ◽  
Human Bone ◽  
Bending Test ◽  
Bovine Bone ◽  
X Ray ◽  
Compression Load ◽  
Bone Powder ◽  
Porous Bioceramic ◽  
Alternative Choice

Bovine bone xenograft was selected bioactive material currently widespread acceptable for using as human bone void filler. In this paper we described a new porous bioceramic block fabricated from bovine bone powders mixed with calcium phosphate glass. The characterized methods were atomic absorption spectrometer, x-ray diffraction, scanning electron microscope, energy dispersion x-ray spectroscopy, diffusion test, bending test, compressive test and Archimedes’ principle. The final products showed interconnecting pores size range 100 to 500 mm, apparent porosity about 52% and mole ratio of Ca:P as 1.65. The toxic elements such as arsenic, cadmium, mercury, and lead were lower standard limits of ASTM I (American Society for Testing and Materials International). The samples had a compressive strength more than 400 kg/cm2. So, this object can be useful as an alternative choice for human bone substitute in the vertical compression load bearing area.

scholarly journals Effects of Bovine Bone Powder and Calcium Carbonate as a Dietary Calcium Source on Plasma and Bone Calcium Metabolism in Rats.

1991 ◽  
Vol 44 (6) ◽  
pp. 479-485 ◽  
Author(s):  
Toshio OKANO ◽  
Naoko TSUGAWA ◽  
Raita HIGASHINO ◽  
Tadashi KOBAYASHI ◽  
Chie IGARASHI ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Calcium Metabolism ◽  
Dietary Calcium ◽  
Bovine Bone ◽  
Bone Powder ◽  
Bone Calcium ◽  
Calcium Source

scholarly journals HIGH-STRENGTH CALCIUM PHOSPHATE GLASS COMPOSITES CONTAINING β-Ca(PO3)2 FIBERS

1996 ◽  
Vol 6 (0) ◽  
pp. 75-78 ◽  
Author(s):  
TOSHIHIRO KASUGA ◽  
YOSHIO OTA ◽  
MASAYUKI NOGAMI ◽  
YOSHIHIRO ABE
Keyword(s):  
Calcium Phosphate ◽  
Phosphate Glass ◽  
High Strength ◽  
Glass Composites

Biocompatibility Evaluation of Zeolite Compared to Bone HA, Calcium Phosphate (Ca2PO4) and Eugenol Paste

2005 ◽  
Vol 284-286 ◽  
pp. 561-564 ◽  
Author(s):  
A.P.M. Schainberg ◽  
Lutfiye Sevgi Özyeğin ◽  
P. Kursuoğlu ◽  
Patricia Valério ◽  
Alfredo Goes ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Calcium Phosphate ◽  
Optical Microscopy ◽  
Cellular Proliferation ◽  
Bovine Bone ◽  
Collagen Production ◽  
Vacuole Formation ◽  
Apoptosis Index ◽  
Bone Calcium

The biocompatibility of Zeolite was evaluated, in vitro, compared to a control and to three different biomaterials: hydroxyapatite from bovine bone, calcium phosphate and a commercial eugenol paste. The Zeolite did not affect cellular proliferation neither the alkaline phosphatase and collagen production. The apoptosis index of the zeolite groups were similar to control and optical microscopy observations did not show any morphological cell change, except the some cytoplasmatic vacuole formation.

Drug release kinetics from biodegradable UV-transparent hollow calcium-phosphate glass fibers

2017 ◽  
Vol 191 ◽  
pp. 116-118 ◽  
Author(s):  
Edoardo Ceci-Ginistrelli ◽  
Carlotta Pontremoli ◽  
Diego Pugliese ◽  
Nadia Barbero ◽  
Nadia G. Boetti ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Drug Release ◽  
Phosphate Glass ◽  
Release Kinetics ◽  
Glass Fibers ◽  
Drug Release Kinetics

Porous bioceramic bead prepared by calcium phosphate with sodium alginate gel and PE powder

2008 ◽  
Vol 28 (7) ◽  
pp. 1149-1158 ◽  
Author(s):  
Y.C. Fu ◽  
M.L. Ho ◽  
S.C. Wu ◽  
H.S. Hsieh ◽  
C.K. Wang
Keyword(s):  
Calcium Phosphate ◽  
Sodium Alginate ◽  
Alginate Gel ◽  
Porous Bioceramic

Chitosan/poly(vinyl alcohol)/bovine bone powder biocomposites: A potential biomaterial for the treatment of atopic dermatitis-like skin lesions

2016 ◽  
Vol 148 ◽  
pp. 115-124 ◽  
Author(s):  
Nátali O. Alves ◽  
Gabriela T. da Silva ◽  
Douglas M. Weber ◽  
Cristiane Luchese ◽  
Ethel A. Wilhelm ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Vinyl Alcohol ◽  
Skin Lesions ◽  
Poly Vinyl Alcohol ◽  
Bovine Bone ◽  
Bone Powder
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