Effects of Bovine Bone Powder and Calcium Carbonate as a Dietary Calcium Source on Plasma and Bone Calcium Metabolism in Rats.

Our objective is invention of new medical products in Thailand by Thai scientists, for human bone substitute, from cow bone. In the previous research experiments, the cow bone-calcium phosphate glass composites had adequate scientific properties to be used as medical objects including, 95% of principal molecules were inorganic hydroxyapatite, no contaminating dangerous heavy metal over standard limits (cadmium,arsenic,mercury,lead), high vertical compressive strength (more than 400 kg/cm2), and no adverse reactions inside the laboratory animals. In this research, we made cranialfixator buttons from bovine bone-calcium phosphate glass composites, intended for neurosurgical skull closure, tested in 10 patients and follow up for at least 6 months. The results revealed that our inventions have easily performance, really effectiveness,and entirely non-complications.

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Description of a Simple Model for the Study of Bone Calcium Metabolism

Nuklearmedizin ◽

10.1055/s-0037-1620923 ◽

1980 ◽

Vol 19 (01) ◽

pp. 11-15

Author(s):

G. Roncari ◽

L. Rapisardi ◽

L. Conte ◽

G. Pedroli

Keyword(s):

Simple Model ◽

Calcium Metabolism ◽

Good Description ◽

Radioactive Tracer ◽

Normal Subjects ◽

Bone Diseases ◽

Compartment System ◽

Bone Calcium ◽

Finite Period ◽

Kinetics Of

A simple model for the study of bone calcium metabolism is proposed. It describes the kinetics of a radioactive tracer in terms of an open single compartment system with an expanding volume for a finite period of time. In addition to the simplicity of the hypotheses introduced, the model is able to give a good description of the biological processes which regulate calcium kinetics. Moreover the functional parameters can be easily calculated, even just graphically. 15 normal subjects and 22 patients affected by various bone diseases were studied. The results were compared with those obtained by using the model proposed by Burkinshaw et al. and the method described by Reeve et al.

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Effect of Anchovy Treated with Ethanol, Citric Acid and Dietary Calcium Supplements on Calcium Metabolism in Rats

Journal of the Korean Society of Food Science and Nutrition ◽

10.3746/jkfn.2006.35.7.860 ◽

2006 ◽

Vol 35 (7) ◽

pp. 860-865 ◽

Cited By ~ 5

Keyword(s):

Citric Acid ◽

Calcium Metabolism ◽

Dietary Calcium ◽

Calcium Supplements

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Effect of calcium source, dietary calcium concentration, and gestation phase on various bone characteristics in gestating gilts2,3

Journal of Animal Science ◽

10.2527/1993.71113003x ◽

1993 ◽

Vol 71 (11) ◽

pp. 3003-3010 ◽

Cited By ~ 7

Author(s):

G. L. Walker ◽

D. M. Danielson ◽

E. R. Peo ◽

R. F. Mumm

Keyword(s):

Calcium Concentration ◽

Dietary Calcium ◽

Calcium Source

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Chitosan/poly(vinyl alcohol)/bovine bone powder biocomposites: A potential biomaterial for the treatment of atopic dermatitis-like skin lesions

Carbohydrate Polymers ◽

10.1016/j.carbpol.2016.04.049 ◽

2016 ◽

Vol 148 ◽

pp. 115-124 ◽

Cited By ~ 21

Author(s):

Nátali O. Alves ◽

Gabriela T. da Silva ◽

Douglas M. Weber ◽

Cristiane Luchese ◽

Ethel A. Wilhelm ◽

...

Keyword(s):

Atopic Dermatitis ◽

Vinyl Alcohol ◽

Skin Lesions ◽

Poly Vinyl Alcohol ◽

Bovine Bone ◽

Bone Powder

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Identification of a Novel Bone/Calcium Metabolism-regulating Factor in Porcine Pancreas

Journal of Biological Chemistry ◽

10.1074/jbc.271.38.23230 ◽

1996 ◽

Vol 271 (38) ◽

pp. 23230-23234 ◽

Cited By ~ 2

Author(s):

Elzbieta Izbicka ◽

Toshiyuki Yoneda ◽

Yoshito Takaoka ◽

Diane Horn ◽

Paul Williams ◽

...

Keyword(s):

Calcium Metabolism ◽

Porcine Pancreas ◽

Bone Calcium

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Effect of Ca(OH)2 and Heat Treatment on The Physico-Chemical Properties of Bovine Bone Powder; a Material Useful for Medical, Catalytic, and Environmental Applications

Materials Science ◽

10.5755/j01.ms.26.1.21219 ◽

2019 ◽

Vol 26 (1) ◽

pp. 114-119

Author(s):

Naseer Ahmed KHAN ◽

Mukhtiar AHMED ◽

Naveed ul Hasan SYED ◽

Matthew DREWERY

Keyword(s):

Heat Treatment ◽

Calcium Ions ◽

Bone Matrix ◽

Chemical Properties ◽

Calcium Content ◽

Bovine Bone ◽

Physico Chemical ◽

Bone Powder ◽

Temperature Ranges ◽

Oily Liquid

In this study the authors investigated the effect of alkali (Ca(OH)2) and heat treatment on the physico-chemical properties of bovine bone powder. For this purpose, raw and alkali treated samples were heated separately at temperatures of 400 °C, 600 °C, 800 °C, and 1000 °C. A combination of characterization techniques, such as TGA, XRD, N2-adsorbtion isotherms, and EDX were used. It was found that the boiling of cleaned solid pieces of bones in 2 molar Ca(OH)2 solution results in a mass loss of about 10 % (mainly discards oily liquid). TGA analysis affirms that the hydrocarbons of bone matrix are partially extractable (~ 10 %) in the boiling alkaline solution. The color of raw and treated bone samples remained similar, that is changing from yellowish white to grayish black before turning into white over temperatures ranging from 30 °C (room temperature), 400 – 600 °C, and 800 – 1000 °C, respectively. Moreover, XRD signatures were also comparable at unified temperature ranges, however, it was noted that carbonization due to heating engenders a significant change in the intensities of the x-ray reflections. Despite of having similarities, surface area of raw and treated bones at 400 °C, 600 °C and 800 °C were found to be different, indicative of a chemical interactions of calcium ions with bone. Quite interestingly, TGA, XRD, and N2-adsorbtion isotherms support the argument that a limited amount of calcium ions diffuses into the vacancies or interstitial sites of bone lattice. Furthermore, EDX analysis of the samples calcined at 1000 °C confirms that the Ca(OH)2 treatment increases the total calcium content of hydroxylapatite (inorganic part of bone matrix).

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Studies in the absorption and excretion of certain minerals by poultry. III. The influence of different levels of dietary calcium upon the retention of calcium, phosphorus, carbonate and chloride

The Journal of Agricultural Science ◽

10.1017/s0021859600024023 ◽

1946 ◽

Vol 36 (4) ◽

pp. 283-288 ◽

Cited By ~ 2

Author(s):

Cyril Tyler

Keyword(s):

Calcium Carbonate ◽

Dietary Calcium ◽

Egg Laying ◽

Carbonate Content ◽

Phosphorus Excretion ◽

Calcium Carbonate Content ◽

High Calcium ◽

Calcium Phosphorus ◽

Different Levels

1. The daily retention of calcium, carbonate, phosphorus and chloride was studied using four birds and changing the calcium carbonate content of the ration every 5 days for 15 days.2. It was shown that high calcium diets result in a much lower retention of calcium and thin-shelled eggs are produced.3. Retention of calcium was higher in the laying than in the non-laying bird when calcium carbonate was fed.4. High calcium diets depressed the retention of phosphorus, and in one case the retention was negative, even when no eggs were laid. Laying birds gave negative values for retention because of the heavy phosphorus excretion associated with egg laying.5. High calcium diets also depressed the retention of chloride, and on occasion led to negative retention values.

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Insulin-Like Growth Factor I and Growth Hormone (GH) Treatment in GH-Deficient Humans: Differential Effects on Protein, Glucose, Lipid, and Calcium Metabolism1

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem.85.4.6541 ◽

2000 ◽

Vol 85 (4) ◽

pp. 1686-1694 ◽

Cited By ~ 1

Author(s):

Nelly Mauras ◽

Kimberly O. O’Brien ◽

Susan Welch ◽

Annie Rini ◽

Kevin Helgeson ◽

...

Keyword(s):

Growth Factor ◽

Muscle Strength ◽

Fat Mass ◽

Calcium Metabolism ◽

Insulin Like Growth Factor ◽

Oxidation Rates ◽

Factor I ◽

Bone Calcium ◽

Growth Factor I ◽

Glucose Output

We examined the effects of recombinant human (rh) insulin-like growth factor I (IGF-I) vs. rhGH in a variety of metabolic paths in a group of eight severely GH-deficient young adults using an array of contemporary tools. Protein, glucose, and calcium metabolism were studied using stable labeled tracer infusions of l-[1-13C]leucine,[ 6,6-2H2]glucose, and 42Ca and 44Ca; substrate oxidation rates were assessed using indirect calorimetry; muscle strength was determined by isokinetic and isometric dynamometry of the anterior quadriceps, as well as growth factors, hormones, glucose, and lipid concentrations in plasma before and after 8 weeks of rhIGF-I (60 μg/kg, sc, twice daily), followed by 4 weeks of washout, then 8 weeks of rhGH (12.5 μg/kg·day, sc); the treatment order was randomized. In the doses administered, rhIGF-I and rhGH both increased fat-free mass and decreased the percent fat mass, with a more robust decrease in the percent fat mass after rhGH; both were associated with an increase in whole body protein synthesis rates and a decrease in protein oxidation. Neither hormone affected isokinetic or isometric measures of skeletal muscle strength. However, rhGH was more potent than rhIGF-I at increasing lipid oxidation rates and improving plasma lipid profiles. Both hormones increased hepatic glucose output, but rhGH treatment was also associated with decreased carbohydrate oxidation and increased glucose and insulin concentrations, indicating subtle insulin resistance. Neither hormone significantly affected bone calcium fluxes, supporting the concept that these hormones, by themselves, are not pivotal in bone calcium metabolism. In conclusion, rhIGF-I and rhGH share common effects on protein, muscle, and calcium metabolism, yet have divergent effects on lipid and carbohydrate metabolism in the GH-deficient state. These differences may allow for better selection of treatment modalities depending on the choice of desired effects in hypopituitarism.

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