scholarly journals Morphometric Study of Rat Sciatic Nerve Recovery after Three Nerve Repair Techniques: Epineural Suture, Polyethylene Glycol Hydrogel and Fibrin Sealant

2021 ◽  
Vol 39 (3) ◽  
pp. 677-682
Author(s):  
O Goncharuk-Oleksii ◽  
I Savosko-Serhii ◽  
I Petriv-Taras ◽  
V Medvediev-Volodymyr ◽  
I Tsymbaliuk-Vitaly
Keyword(s):  
Polyethylene Glycol ◽  
Sciatic Nerve ◽  
Fibrin Sealant ◽  
Nerve Repair ◽  
Morphometric Study ◽  
Rat Sciatic Nerve ◽  
Nerve Recovery ◽  
Repair Techniques

scholarly journals Learning curve in rat dissection for experimental sciatic nerve repair

2019 ◽  
pp. 243-248
Author(s):  
Marin Andrei ◽  
Marin Georgiana Gabriela ◽  
Dobrete Nicoleta Amalia ◽  
Enescu Dan Mircea
Keyword(s):  
Sciatic Nerve ◽  
Learning Curve ◽  
Nerve Regeneration ◽  
Experimental Model ◽  
Rat Model ◽  
Surgical Intervention ◽  
Nerve Repair ◽  
Learning Curves ◽  
Rat Sciatic Nerve ◽  
Nerve Surgery

The baseline for any key research in nerve regeneration is an experimental model and the sciatic nerve in the rat model is the workhorse in this field. Although physically resistant to external traumas, a surgical intervention constitutes a major distress even for a rat. In the following presentation, we will analyse the learning curves for different stages in the rat sciatic nerve surgery as well as possible factors which influence these times.

scholarly journals Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model

2018 ◽  
Vol 6 (5) ◽  
pp. 1059-1075 ◽  
Author(s):  
C. R. Carvalho ◽  
S. Wrobel ◽  
C. Meyer ◽  
C. Brandenberger ◽  
I. F. Cengiz ◽  
...  
Keyword(s):  
Sciatic Nerve ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Experimental Work ◽  
Nerve Repair ◽  
Peripheral Nerve Regeneration ◽  
Gellan Gum ◽  
In Vivo Study ◽  
Rat Sciatic Nerve

This experimental work considers the innovative use of the biomaterial Gellan Gum (GG) as a luminal filler for nerve guidance channels.

scholarly journals Diffusion Magnetic Resonance Imaging Predicts Peripheral Nerve Recovery in a Rat Sciatic Nerve Injury Model

2020 ◽  
Vol 145 (4) ◽  
pp. 949-956
Author(s):  
Angel F. Farinas ◽  
Isaac V. Manzanera Esteve ◽  
Alonda C. Pollins ◽  
Nancy L. Cardwell ◽  
Christodoulos Kaoutzanis ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Sciatic Nerve ◽  
Peripheral Nerve ◽  
Nerve Injury ◽  
Diffusion Magnetic Resonance Imaging ◽  
Resonance Imaging ◽  
Rat Sciatic Nerve ◽  
Injury Model ◽  
Nerve Recovery

scholarly journals Evaluation of morphological and functional nerve recovery of rat sciatic nerve with a Hyaff11-based nerve guide

2006 ◽  
Vol 3 (2) ◽  
pp. 67-76
Author(s):  
K. Jansen ◽  
Y. Ludwig ◽  
M. J. A. van Luyn ◽  
A. A. Gramsbergen ◽  
M. F. Meek
Keyword(s):  
Sciatic Nerve ◽  
Rat Sciatic Nerve ◽  
Nerve Recovery

scholarly journals Mesenchymal Stem Cells Enhance Nerve Regeneration in a Rat Sciatic Nerve Repair and Hindlimb Transplant Model

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Damon S. Cooney ◽  
Eric G. Wimmers ◽  
Zuhaib Ibrahim ◽  
Johanna Grahammer ◽  
Joani M. Christensen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Sciatic Nerve ◽  
Nerve Regeneration ◽  
Nerve Repair ◽  
Rat Sciatic Nerve ◽  
Transplant Model

Effects of delayed nerve repair on regeneration of rat sciatic nerve

1995 ◽  
Vol 9 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Tadahisa Urabe ◽  
Qing Zhao ◽  
Göran Lundborg ◽  
Nils Danielsen
Keyword(s):  
Sciatic Nerve ◽  
Nerve Repair ◽  
Rat Sciatic Nerve

scholarly journals Polyethylene Glycol Fusion of Nerve Injuries: Review of the Technique and Clinical Applicability

2020 ◽  
Author(s):  
Duncan S. Van Nest ◽  
David M. Kahan ◽  
Asif M. Ilyas
Keyword(s):  
Polyethylene Glycol ◽  
Functional Recovery ◽  
Wallerian Degeneration ◽  
Neuromuscular Junctions ◽  
Nerve Repair ◽  
Nerve Fibers ◽  
Peripheral Nerve Injuries ◽  
Nerve Injuries ◽  
Novel Technique ◽  
Repair Techniques

AbstractTraumatic peripheral nerve injuries present a particular challenge to hand surgeons as mechanisms of nerve-healing pose serious limitations to achieving complete functional recovery. The loss of distal axonal segments through Wallerian degeneration results in the loss of neuromuscular junctions and irreversible muscle atrophy. Current methods of repair depend on the outgrowth of proximal nerve fibers following direct end-to-end repair or gap repair techniques. Investigational techniques in nerve repair using polyethylene glycol (PEG) nerve fusion have been shown to bypass Wallerian degeneration by immediately restoring nerve axonal continuity, thus resulting in a rapid and more complete functional recovery. The purpose of this article is to review the current literature surrounding this novel technique for traumatic nerve repair, paying particular attention to the underlying physiology of nerve healing and the current applications of PEG fusion in the laboratory and clinical setting. This article also serves to identify areas of future investigation to further establish validity and feasibility and encourage the translation of PEG fusion into clinical use.

Cytochemistry and morphometry of rat sciatic nerve following laser and suture treatments

1986 ◽  
Vol 44 ◽  
pp. 128-129
Author(s):  
A. Shah ◽  
J. E. Bailes ◽  
V. Sahgal ◽  
L. J. Cerullo
Keyword(s):  
Sciatic Nerve ◽  
Horseradish Peroxidase ◽  
Light Microscopy ◽  
Morphological Study ◽  
Wallerian Degeneration ◽  
Nerve Repair ◽  
Nerve Fibers ◽  
Relative Efficacy ◽  
Tracer Technique ◽  
Rat Sciatic Nerve

The success of nerve repair treatment can be measured by examining the factors (Wallerian degeneration) that prevent functional recovery, and determining the extent of regeneration of proximal axon sprouts in the endoneurial environment of the distal fascicles. In the present study, the neurosurgical alignment of fascicles was attempted by laser as well as suture microsurgery of transected rat sciatic nerve and the relative efficacy of the two procedures was evaluated after 6 and 12 weeks by Neurophysiological Study, Morphological Study with light microscopy, ultrastructure, and the permeability of blood-nerve barrier using horseradish peroxidase (HRP) tracer technique, and Morphometry of the nerve fibers.

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