scholarly journals FORENSIC CASES IN THE NORTH OF CHILE: DETERMINATION OF ANTIDEPRESSANT DRUGS IN HUMAN WHOLE BLOOD

2013 ◽  
Vol 58 (2) ◽  
pp. 1733-1736 ◽  
Author(s):  
FELIPE BRAVO ◽  
CARMEN ZAMBRA ◽  
KARINA VENEGAS ◽  
DAVID RIOS ◽  
PEDRO BUC CALDERON ◽  
...  
Methods ◽  
2006 ◽  
Vol 38 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Tanja Breinig ◽  
Martina Sester ◽  
Urban Sester ◽  
Andreas Meyerhans

2007 ◽  
Vol 66 (9-10) ◽  
pp. 735-739 ◽  
Author(s):  
Qing Xu ◽  
Mei Huang ◽  
Micong Jin ◽  
Qilong Ren

2003 ◽  
Vol 1014 (1-2) ◽  
pp. 93-101 ◽  
Author(s):  
Chien-Yuan Kuo ◽  
Hsin-Lung Wu ◽  
Hwang-Shang Kou ◽  
Shyh-Shin Chiou ◽  
Deng-Chyang Wu ◽  
...  

2002 ◽  
Vol 29 (6) ◽  
pp. 1073-1080 ◽  
Author(s):  
Gianpiero Boatto ◽  
Maria Virginia Faedda ◽  
Amedeo Pau ◽  
Battistina Asproni ◽  
Sonia Menconi ◽  
...  

2011 ◽  
Vol 76 (4) ◽  
pp. 277-294 ◽  
Author(s):  
Roman Kanďár ◽  
Pavla Žáková ◽  
Miroslava Marková ◽  
Halka Lotková ◽  
Otto Kučera ◽  
...  

We describe a relatively simple method for the determination of glutathione (GSH) and glutathione disulfide (GSSG) in human whole blood. We have used an HPLC with coulometric electrochemical detection for the simultaneous measurement of GSH and GSSG. Diluted and filtered trichloroacetic acid extracts were injected directly into the HPLC system and were eluted isocratically on a Polaris 5u C18-A, 250 × 4.6 mm analytical column. Glutathione in samples extracted with trichloroacetic acid and diluted with 1.0 mMhydrochloric acid was stable at 4 °C for at least 8 h. The analytical performance of this method is satisfactory: the intra-assay and inter-assay coefficients of variation were below 10%. Quantitative recoveries from spiked whole blood samples were at intervals 91.6–97.6% for GSH and 85.0–104.4% for GSSG. The linear range is 5.0–2000.0 μmol/l, with a detection limit of 2.1 μmol/l (signal-to-noise ratio = 3) for GSH and 2.0–250.0 μmol/l, with a detection limit of 0.9 μmol/l for GSSG.


2019 ◽  
Vol 1118-1119 ◽  
pp. 40-50 ◽  
Author(s):  
Marcello Locatelli ◽  
Kenneth G. Furton ◽  
Angela Tartaglia ◽  
Elena Sperandio ◽  
Halil I. Ulusoy ◽  
...  

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