scholarly journals The Russian scientists’ quality of life and cognitive status

Author(s):  
Tatiana P Vasileva ◽  
Mihkail A Yakushin ◽  
Ekaterina V Makarova ◽  
Polina I Reshetnikova ◽  
Guzal E Shukurlaeva ◽  
...  

Aim of the study was assessment of executive functions and quality of life (QoL) among scientists aged 22-80 years working in state research centers. The screening test included several questionnairs: “Cognitive screening”, “Age is not a barrier”, “Geriatric Depression Scale" (GDS) and Social Functioning 36 (SF-36) survey. According to the assessment, the group of scientists showed problems related to physical health disorders and presence of numerous risk factors for professional efficiency decline. High rate of preasthenia (39.62%) and asthenia syndrome (11.32%) was identified. This might be due to high level of stress and informational load that causes depletion of functional organism reserves. The rate of cognitive executive functions decline was low (3.77%), stated in young age and possibly associated with depression and asthenia. In comparison to general population, Russian scientists showed a generally high level of quality of life (more than 70% in all domains), best indicators on the scales of "Body Pain" and "Vitality", but lower indicators of "Role functioning” due to the emotional state. In general, scientists’ quality of life decreased with age, especially "Physical Functioning" and "Body Pain" scales. Social skills such as "Role functioning due to emotional state" increased with age. In the scientists group, connection between cognitive functions and the quality of life was observed. Specifically, between "Physical Functioning", "General Health", "Vitality", "Social Functioning" and "Mental Health".

2020 ◽  
Vol 11 (01) ◽  
Author(s):  
Reena . ◽  
Bimla Dhanda

The study was conducted in five cultural zones of Haryana state. For the rural sample 400 widow elderly women of age group 60-75 years were selected. Quality of life scale developed by World Health Organization (1997) was accessed to quality of life of widow elderly women. The questionnaire short form-36 health survey by Mchorney (1993) was used to assess the health status of widow elderly women. Clearly shows that relationship between aspects of perceived health status and quality of life among widow elderly women. Physical aspects of quality of life was positively significantly correlated with vitality (r =0.13**, p 0.01), body pain (r =0.39**, p 0.01), physical role functioning (r= 0.23**, p 0.01) , mental health ((r =0.10*, p 0.01) negatively significantly correlated with general health perception (r = -0.17**, p 0.01) and emotional role functioning (r = - 0.28**, p 0.01). Psychological aspects of quality of life was positively significantly correlated with physical functioning (r =0.13**, p 0.01) and body pain (r =0.10*, p 0.05). Another aspects social relationship of quality of life was negatively significantly correlated with physical functioning (r = -0.18**, p 0.01), body pain (r = -0.12**, p 0.01) and social role functioning (r = -0.11**, p 0.01), Physical role functioning, Emotional role function was negatively correlated with (r = 0.28**, p 0.01). Further aspects of environment was positively significantly correlated with vitality (r = 0.09*, p 0.05), Physical Functioning (r = 0.46**, p 0.01), body pain (r = 0.14**, p 0.01), General health perception (r = 0.30**, p 0.01) and physical role functioning (r = - 0.09*, p 0.05).


2006 ◽  
Vol 64 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Mara Renata Fernandes ◽  
Luciane B.C. Carvalho ◽  
Gilmar F. Prado

CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.


2001 ◽  
Vol 94 (2) ◽  
pp. 211-216 ◽  
Author(s):  
Helen C. Martin ◽  
Jagjit Sethi ◽  
Dorothy Lang ◽  
Glen Neil-Dwyer ◽  
Mark E. Lutman ◽  
...  

Object. The aim of this study was to assess whether outcomes from excision of acoustic neuroma vary among patients and have a material impact on their quality of life (QOL). Methods. A questionnaire concerning postoperative symptoms and the Short Form 36 (SF-36) QOL instrument were mailed to 97 consecutive patients who had undergone acoustic neuroma surgery via the translabyrinthine approach. The survey response rate was 78% and the symptomatology was consistent with other reports, supporting the representativeness of the sample. The respondents' QOL was rated significantly below published norms and their work capacity was reportedly reduced. Specifically, the following SF-36 dimensions were reduced: physical functioning and role-physical, together with vitality, general health, and social functioning. Greater numbers of postoperative symptoms and larger tumors were associated with a worse rating of physical functioning. More severe balance problems were associated with lower ratings of social functioning. The disparity between the patient's self-estimate and self-measurement and the clinician's assessment of the patient's facial functioning raises doubts about the validity of subjective reports and assessment. Conclusions. The present study supports the use of generic QOL measures to assess outcome and to draw comparisons between different populations.


2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S150-S150
Author(s):  
Amelia Austen ◽  
Carina Hou ◽  
Khushbu Patel ◽  
Keri Brady ◽  
Gabrielle G Grant ◽  
...  

Abstract Introduction Burn injuries can have major long-term effects on the health and quality of life for children and adolescents. This study narratively reviewed the health outcomes literature focusing on the impact of burn injury for children aged 5–18. Methods Literature targeting pediatric outcomes was reviewed to identify the effects of burns on children aged 5–18 (n=16). Inclusion criteria included studies that focused on the impact of burns on health and quality of life and were age-appropriate for this population. Articles were identified via PubMed, Web of Science, and manual reference checks. Data collected included the outcomes and health domains assessed in each article and the findings of the effects of the burn injury on those specific outcomes. The Preschool LIBRE Conceptual Model served as a ‘domains framework’ to guide the identification of outcomes and health domains. Results Long-term burn-specific outcomes and broad health domains identified were physical functioning (n=9), psychological functioning (n=12), social functioning (n=4), symptoms (n=8), and family (n=7). Some studies exclusively focused on one domain whereas others assessed two domains or more. Subdomains such as upper extremity functioning and functional independence were addressed in the physical functioning domain. Psychological functioning outcomes included subdomains such as emotional health and behavioral problems. Social functioning outcomes evaluated subdomains such as problems with peers and social participation. The symptoms domain addressed post-burn pain and itch. Family outcomes subdomains such as parental satisfaction with appearance and general family functioning were identified. Conclusions Burn-specific outcomes and health domains assessing the effects of burns on children aged 5–18 were identified among 16 studies. There is a need for a comprehensive assessment tool that more precisely measures the impact of burn injury across these domains. This work will inform the development of the School-Aged Life Impact Burn Recovery Evaluation (LIBRE) Computer Adaptive Test (CAT) Profile – a new outcome metric for children and adolescents with burns. Applicability of Research to Practice This review is relevant to researchers and clinicians assessing health outcomes and measuring burn recovery in children aged 5–18.


2020 ◽  
Vol 26 (6) ◽  
pp. 1421-1428
Author(s):  
Ebrahim Salehifar ◽  
Ghasem Janbabaei ◽  
Abbas Alipour ◽  
Nasim Tabrizi ◽  
Razieh Avan

Purpose Taxane-induced peripheral neuropathy (TIPN) is a common and bothersome toxicity. This study aimed to determine the incidence and severity of TIPN in patients with breast cancer and to investigate the relationship between TIPN and quality of life. Methods A total of 82 breast cancer patients with TIPN symptoms were included in this study. The criteria of National Cancer Institute-Common Terminology Criteria for Adverse Events (NCI-CTCAE v4.03) and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30, version 3.0) were used to evaluate grading of sensory neuropathy and quality of life, respectively. Analysis of the data was done by IBM SPSS statistics version 23. Results A total of 346 patients received taxane-based chemotherapy and 82 patients (23.7%) experience TIPN. The mean (SD) global health status/quality of life, physical functioning, role functioning, and pain subscales were 60.63 (5.26), 80.64 (9.05), 81.77 (10.41), and 43.88 (11.27), respectively. There were significant negative correlations between global health status/quality of life, physical functioning, and role functioning subscales with the grade of neuropathy (r = −0.33, −0.80, and −0.61, respectively) and positive correlation between pain subscale and the grade of neuropathy (r = 0.70). Conclusion This study shows a clear association between TIPN and worsened quality of life. These findings emphasize on detecting and management of TIPN in an effort to improve the quality of life of breast cancer patients.


Blood ◽  
2011 ◽  
Vol 118 (21) ◽  
pp. 1989-1989
Author(s):  
Liesbeth C. de Wreede ◽  
Maggie Watson ◽  
Donald Milligan ◽  
Mauricette Michallet ◽  
Peter Dreger ◽  
...  

Abstract Abstract 1989 Objective: High-dose therapy (HDT) and ASCT is the standard of care in a variety of hematologic malignancies. Whereas for some indications a survival advantage for HDT and ASCT has been demonstrated, a benefit only in terms of better progression-free survival has been shown for CLL. Because of this the quality of life (QoL) deserves particular attention. QoL assessment was a major focus of a randomized controlled EBMT-Intergroup trial on the value of HDT compared to observation in first or second remission of CLL (Michallet, Blood, 2011). Methods: 222 patients were enrolled into the study and allocated to either ASCT or observation. In the transplant arm, 72% received HDT and ASCT (for those median time from randomization to transplant was 3.01 months); in the observation arm 9% received ASCT. QoL was assessed with the EORTC QLQ C30 version 3.0, a questionnaire that has to be filled in by the patients. The answers to the questions yielded 15 scores, each on a scale from 0 to 100. The scores represent 15 domains: global health status/QoL, 5 functional scales (100 representing perfect health) and 9 symptom scales (0 representing no complaints). QoL forms had to be completed at randomization and at months 4, 8, 12, and 24. Data on 56%, 53%, 54%, 61%, and 50% of the baseline patients are available for the respective periods. Missing forms were not systematically related to baseline variables or relapse. The numbers of drop out due to death at 2 years were 5 patients in the HDT arm and 4 patients in the control arm. All QoL outcomes were analyzed with mixed models according to the intent to treat principle. Time (as factor), age, gender, treatment arm and the interaction of time and treatment arm were modelled as fixed effects, whereas individual random effects were added for the intercept. Results: The mean values for global health status/QoL, physical functioning, role functioning and social functioning over time for the transplant and the observation group are shown in Figure 1. Global health status/QoL at 4 months (estimated effect from the multivariate model −7.15, p=0.034) was significantly inferior in the transplant cohort compared to the control group. At 8 months the estimated effect of HDT on global health status/QoL was −3.06 (p=0.36). This difference further diminished over the first year (estimate at 1 year −0.53, p=0.87). QoL did not decrease independently from the treatment during the first 2 years. The same global pattern of change over time was observed for physical functioning, role functioning and social functioning; however, the treatment impact was still significant at 8 months for physical functioning (-6.58; p=0.025) and social functioning (-11.18; p=0.014). No significant covariate effects could be delineated for either of these scales apart from age having a beneficial effect on social functioning. Conclusions: Quality of life is affected multi-dimensionally in the first year after high-dose therapy and autologous stem cell support. The negative impact of HDT on QoL has disappeared after two years. Patients should be informed that HDT followed by ASCT impairs quality of life in the first year after transplantation. Disclosures: No relevant conflicts of interest to declare.


2020 ◽  
Vol 16 (2) ◽  
pp. 16-22
Author(s):  
O.A. Alifer

Relevance. Hypertension is one of the most common chronic diseases, for which currently the goal of therapy is not so much recovery as improving circulatory function with a satisfactory quality of life. Objective: to determine the impact of different degrees of hypertension on quality of life in female and male patients. Materials and methods. 126 patients with arterial hypertension underwent examination, including 86 women (68%), 40 men (32%) aged 40 to 81 years (mean age 61.9 ± 0.3 years). Arterial hypertension of I degree had 19 people (15.1%), II degree - 65 patients (51.6%), III degree - 42 people (33.3%). The control group consisted of 43 healthy individuals who did not differ from the main group in terms of demographics. Surveys of patients to assess the quality of life conducted with the questionnaire SF-36 (Short Form-36) at each follow-up. Quality of life indicators has value in points. Results. The analysis of quality of life indicators in the group of healthy people found that the level of quality of life in men is much higher than in healthy women: "physical pain", "role functioning" - P1-P2> 0.5; "Physical functioning" - P1-P2 <0.001; "Physical health" - P1-P2> 0.5, except for the scale "general health" - P1-P2 <0.05 (77.2 ± 3.02 vs. 63.75 ± 2.81). The comparison of the quality of life of patients with hypertension of I degree and patients with arterial hypertension of III degrees found reliable differences on the scales "Vitality" (P1-P3 <0.001), and "Social functioning" (P1-P3 <0.5). In patients with II and III degrees of arterial hypertension indicators of quality of life were low in themselves and differed on a scale "role functioning" of the questionnaire: "Vital force" (P2-P3> 0,5); "Role functioning" (P2-P3 <0.5); "Mental health" (P2-P3> 0.5). Patients with hypertension of the I degree in comparison with arterial hypertension of the II degree had reliably higher indicators of quality of life on scales "vital force" (80,0 ± 3,93 points) and "role functioning" (77,1 ± 4,04 points) ), but reduced indicators of "social functioning" and "mental health" (48.7 ± 7.35 and 47.41 ± 2.39 points, respectively). Patients with hypertension of I degree and III degree showed reliable differences on the scales "vital force" (P1-P3 <0.001) and "social functioning" (P1-P3 <0.5); and patients with hypertension of II and III degrees showed a significant decrease in all indicators of quality of life, especially on the scales "social functioning" and "mental health" (up to 31.5 ± 5.19 and up to 40.31 ± 2.23 points, respectively). Patients with hypertension of I degree had a decrease in general health (87.1 ± 3.16), physical function (82.6 ± 2.86), and physical pain (87.1 ± 3.16). Patients with II degree of hypertension had a significant reduction in role functioning (32.4 ± 5.19), physical pain, and general health (36.0 ± 6.12 and 42.26 ± 2.68 points, respectively). Conclusions. Hypertension significantly affects the quality of life. The state of health of patients with hypertension significantly limited their physical activity.


1997 ◽  
Vol 87 (11) ◽  
pp. 507-511 ◽  
Author(s):  
LA Drake

The author reviews the current knowledge of the impact of onychomycosis on quality of life. Like other visible disorders of the integumentary system, onychomycosis affects many aspects of life, including physical functioning, interpersonal interactions, and emotional state. After examining the nature of quality of life and the study instruments used to measure it, the author reviews several studies that have examined the relationship between onychomycosis and quality of life. The author concludes that onychomycosis is a significant medical problem that has a great impact on patients' lives and should therefore be treated as definitively as possible.


2016 ◽  
Vol 30 (2) ◽  
pp. 247-261 ◽  
Author(s):  
Philip D. St. John ◽  
Depeng Jiang ◽  
Robert B. Tate

Objective: To describe quality of life trajectories of older men over a 10-year time frame in mental and physical health domains, and to determine if these trajectories predict death over a subsequent 9-year period. Method: A cohort study of Royal Canadian Air Force aircrew veterans. We used Short Form–36 (SF-36) measures of mental and physical functioning collected prospectively at six time points between 1996 to 2006 (734 men with a mean age of 85.5 [ SD 3.0] years in 2006) to determine trajectories. Continued contact with the cohort from 2006 to 2015 determined subsequent mortality. Results: Men were more likely to maintain high levels of mental functioning than physical functioning. Thirty-seven percent of participants maintained a high level of both mental and physical functioning. Declining function in either mental or physical function was associated with lower survival. Conclusion: Men who maintain physical and mental functioning have a lower mortality rate.


2017 ◽  
Vol 29 (7) ◽  
pp. 1085-1093 ◽  
Author(s):  
Joel Olayiwola Faronbi ◽  
Adenike Ayobola Olaogun

ABSTRACTBackground:This study investigated the impact of caregivers’ burden on health-related quality of life (HRQoL) among the caregivers of older adults, and tested the predictive effect of burden and socio-demographic factors on HRQoL.Methods:The study employed a cross-sectional design. Three hundred and twenty-five caregivers of older adults with chronic illness were purposively selected. Data were collected using the Zarit Burden Interview and Short Form (SF-36) Health Survey. Data were analyzed descriptively and inferentially.Results:Findings revealed that 59.1% of caregivers experienced severe burden. In measuring the HQRoL, respondents performed poorly in seven domains: Role limitation due to emotional problems (19.69 ± 9.46), Energy/fatigue (43.47 ± 16.46), Emotional well-being, (45.83 ± 13.93), Social functioning (49.09 ± 18.46), Role limitation due to physical function (43.33 ± 10.15), Physical functioning (43.6 ± 18.73), and General health (37.31 ± 12.09). Respondents, however, showed a higher score in the pain domain (56.77 ± 35.79). Furthermore, findings revealed a positive correlation between caregivers’ burden and General health (r = 0.342), Emotional well-being (r = 0.222), and Physical functioning (r = 0.083). Similarly, there is a negative correlation between caregivers’ burden and Social functioning (r = –0.618), Role limitation due to physical activities (r = 0.459), Role limitation due to emotional well-being (r = –0.530), and Energy/fatigue domains (r = –0.509). In addition, burden of caregiving (β=–3.142119, p = 0.000) and age (β=0.612752, p = 0.011) are predictors of the quality of life of caregivers.Discussion:This study concluded that there is a high prevalence of caregivers’ burden resulting in poor HQRoL. In addition, burden and age are predictors of the quality of life of caregivers.


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