The right to exit the footnote: a story of rediscovery and revival of Fritz Jahr’s bioethics (with special regard to Italy)

2021 ◽  
Vol 70 (1) ◽  
pp. 11-24
Author(s):  
Iva Rinčić ◽  
Toni Buterin ◽  
Robert Doričić ◽  
Igor Eterović ◽  
Marianna Gensabella ◽  
...  
Keyword(s):  
Special Regard ◽  
Main Motive ◽  
History Of ◽  
To Come ◽  
The Right ◽  
History Of Bioethics ◽  
Van Rensselaer Potter

Despite the numerous works evaluating Fritz Jahr’s importance for bioethics, there is still a widespread practice at best to put his name in some of the footnotes. The similar practice is recognized in Italy and the full appreciation of his work – contrary to the reception of Van Rensselaer Potter’s work – is still to come. First part of this paper is concerned with the mentioned uncommendable practice as a main motive of the article. Second part shortly captures the main facts about life and work of Fritz Jahr. Third part is dedicated to summary of extensive work of Van Rensselaer Potter. Next part reveals the trends and practices in Italy concerning the reception of those two «fathers of bioethics» and delineate the lines of research based on their work. In conclusion the authors call for caution and attentive approach to history of bioethics because mixing those research lines could be at least deceptive if not completely unfruitful.

scholarly journals Muscle contraction: Sliding filament history, sarcomere dynamics and the two Huxleys

2016 ◽  
Vol 2016 (2) ◽  
Author(s):  
John M Squire
Keyword(s):  
Muscle Contraction ◽  
Striated Muscle ◽  
History Of ◽  
Sarcomere Dynamics ◽  
Guiding Principles ◽  
The 1950S ◽  
To Come ◽  
The Right ◽  
Overlapping Sets

Despite having all the evidence needed to come to the right conclusions in the middle of the 1800s, it was not until the 1950s that it was realised by two unrelated Huxleys and their collaborators that striated muscle sarcomeres contain overlapping sets of filaments which do not change much in length and which slide past each other when the muscle sarcomere shortens. It then took quite a while to convince others that this was the case, but now the idea of sliding filaments is fundamental to our understanding of how any muscle works. Here a brief overview of the history of the discovery of sliding filaments and the factors that were missed in the 1800s is followed by an analysis of the more recent experiments which have added to the conviction that all muscles operate on the same guiding principles; two sets of sliding filaments, independent force generators and a mechanism of protein rowing that makes the filaments slide. 

scholarly journals the discovery of the parabolic shape of the projectile trajectory

2001 ◽  
Vol 14 (s1) ◽  
pp. 375-410 ◽  
Author(s):  
emil wohlwill
Keyword(s):  
Intellectual Property ◽  
Experimental Method ◽  
Introductory Overview ◽  
Parabolic Shape ◽  
Fourth Volume ◽  
History Of ◽  
Clear Thinking ◽  
To Come ◽  
The Right ◽  
The Given

in the fourth volume of his history of the experimental method in italy (caverni 1891–1900, 4:506–33), raffaello caverni fulfilled the promise he had made four years earlier in an introductory overview of his work (ibid., 1:135–36): to prove on the basis of the history of the discovery of the parabolic shape of the projectile trajectory that galileo claimed the intellectual property of his eminent contemporaries as his own, and to show how this was accomplished. one had the right to expect that the proponent of such an entirely new opinion in a case which he himself considered to be, in the words of bacon, an instantia praerogativa for the justification of his view, would weigh the value of each individual argument with absolute impartiality and do complete justice to the ambiguity of the given facts. he would have to state his case in compelling logic so that a clear-thinking individual would have no choice, in this case at least, but to believe in the dishonorable theft by a great man. in these expectations we have been disappointed thoroughly by caverni: his argumentation is in all aspects that of a shrewd lawyer who considers it his task to allow only one side of the question to come to light, to collect everything that might be utilized in favor of his biased reading, to hold back anything which might give rise to the idea that things could be viewed in another way. he believed it permissible for his own purposes to operate with presumptions as if they were facts, and to regard as proven what is at best probable.

Some Fundamental Issues in the History of Chinese Painting

1964 ◽  
Vol 23 (2) ◽  
pp. 185-193 ◽  
Author(s):  
Max Loehr
Keyword(s):  
Basic Problem ◽  
Chinese Painting ◽  
Historical Significance ◽  
Simple Question ◽  
History Of ◽  
To Come ◽  
The Right

The history of Chinese painting is a relatively new discipline. None of us who work in that discipline can as yet rely on a binding tradition, accepted methods, or even on established facts of historical significance. It is possible for several critics to arrive at surprisingly contradictory judgments about one and the same work, or sequence of works, or about the meaning of the same evidence. Our judgments, naturally, will change; the work adjudged will not. We have to come to terms with it in the end. Coming to terms, however, does not mean a compromise between opposed views or viewers. It means that the right understanding of the work or sequence in question will sooner or later prevail—that is, the right understanding of the work as a historical monument. But how is this understanding achieved? It is this seemingly simple question, the basic problem facing the historian, that I shall discuss.

Investor-State Dispute Settlement under NAFTA Chapter 11: The Shape of Things to Come?

1998 ◽  
Vol 35 ◽  
pp. 263-290
Author(s):  
J. Anthony VanDuzer
Keyword(s):  
Free Trade Agreement ◽  
Dispute Settlement ◽  
Trade Agreement ◽  
Minimum Standards ◽  
The North ◽  
State Behaviour ◽  
Nafta Chapter 11 ◽  
To Come ◽  
The Right

SummaryRecently, there has been a proliferation of international agreements imposing minimum standards on states in respect of their treatment of foreign investors and allowing investors to initiate dispute settlement proceedings where a state violates these standards. Of greatest significance to Canada is Chapter 11 of the North American Free Trade Agreement, which provides both standards for state behaviour and the right to initiate binding arbitration. Since 1996, four cases have been brought under Chapter 11. This note describes the Chapter 11 process and suggests some of the issues that may arise as it is increasingly resorted to by investors.

Z-line degradation and phagocytosis of sarcomeric fragments in myonecrosis

1983 ◽  
Vol 41 ◽  
pp. 790-791
Author(s):  
Melinda L. Estes ◽  
Samuel M. Chou
Keyword(s):  
Vastus Lateralis ◽  
Inflammatory Myopathy ◽  
Muscle Disease ◽  
White Female ◽  
Inflammatory Cell Infiltrate ◽  
Limb Weakness ◽  
Muscle Diseases ◽  
History Of ◽  
The Right ◽  
Mononuclear Inflammatory Cell

Many muscle diseases show common pathological features although their etiology is different. In primary muscle diseases a characteristic finding is myofiber necrosis. The mechanism of myonecrosis is unknown. Polymyositis is a primary muscle disease characterized by acute and subacute degeneration as well as regeneration of muscle fibers coupled with an inflammatory infiltrate. We present a case of polymyositis with unusual ultrastructural features indicative of the basic pathogenetic process involved in myonecrosis.The patient is a 63-year-old white female with a one history of proximal limb weakness, weight loss and fatigue. Examination revealed mild proximal weakness and diminished deep tendon reflexes. Her creatine kinase was 1800 mU/ml (normal < 140 mU/ml) and electromyography was consistent with an inflammatory myopathy which was verified by light microscopy on biopsy muscle. Ultrastructural study of necrotizing myofiber, from the right vastus lateralis, showed: (1) degradation of the Z-lines with preservation of the adjacent Abands including M-lines and H-bands, (Fig. 1), (2) fracture of the sarcomeres at the I-bands with disappearance of the Z-lines, (Fig. 2), (3) fragmented sarcomeres without I-bands, engulfed by invading phagocytes, (Fig. 3, a & b ), and (4) mononuclear inflammatory cell infiltrate in the endomysium.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

We Have Tasted the Powers of the Age to Come: Thinking the Force of the Event—from Dynamis to Puissance

2018 ◽  
Vol 40 (1) ◽  
pp. 76-94 ◽  
Author(s):  
Thomas Clément Mercier
Keyword(s):  
History Of ◽  
To Come ◽  
Interpretative Model

Responding to the provocative phrase ‘The Age of Grammatology’, I propose to question the notion of ‘age’, and to interrogate the powers or forces, the dynameis or dynasties attached to the interpretative model of historical periodisation. How may we think the undeniable actuality of the event beyond the sempiternal history of ages, and beyond the traditional, onto-teleological chain of power, possibility, force or dynamis that undergirds such history?

COMMONWEALTH Forum: The Politics of Science or the Science of Politics

Commonwealth ◽  
2017 ◽  
Vol 19 (1) ◽  
Author(s):  
John Arway
Keyword(s):  
Public Policy ◽  
Natural Resource ◽  
Factual Information ◽  
The Past ◽  
Difference Of Opinion ◽  
History Of ◽  
The Right ◽  
Scientific Facts ◽  
Environmental Agency ◽  
Laws And Regulations

The challenges of including factual information in public policy and political discussions are many. The difficulties of including scientific facts in these debates can often be frustrating for scientists, politicians and policymakers alike. At times it seems that discussions involve different languages or dialects such that it becomes a challenge to even understand one another’s position. Oftentimes difference of opinion leads to laws and regulations that are tilted to the left or the right. The collaborative balancing to insure public and natural resource interests are protected ends up being accomplished through extensive litigation in the courts. In this article, the author discusses the history of environmental balancing during the past three decades from the perspective of a field biologist who has used the strength of our policies, laws and regulations to fight for the protection of our Commonwealth’s aquatic resources. For the past 7 years, the author has taken over the reins of “the most powerful environmental agency in Pennsylvania” and charted a course using science to properly represent natural resource interests in public policy and political deliberations.

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