scholarly journals Endobronchial hamartoma in a young COVID-19 symptomatic woman. Radical endoscopic treatment with a disposable bronchoscope. Case Report

2021 ◽  
Author(s):  
Carmine Guarino ◽  
Cristiano Cesaro ◽  
Giuseppe La Cerra ◽  
Raffaella Lucci ◽  
Flavio Cesaro ◽  
...  
Keyword(s):  
Pathological Condition ◽  
Lung Parenchyma ◽  
Young Female ◽  
Interventional Pulmonology ◽  
Time In Literature ◽  
Elective Treatment ◽  
Single Use ◽  
Symptomatic Woman ◽  
First Time ◽  
Chest Ct Scan

Pulmonary hamartomas represent the most frequent family of benign lung tumors that typically involve the lung parenchyma and only rarely grow as endobronchial tumors. The elective treatment of endobronchial hamartoma is the bronchoscopic resection, and in those cases in which tumor extension and localization makes it not possible, surgical treatment must be evaluated. Patients with symptomatic COVID-19, hospitalized, frequently undergo a chest CT scan and in some cases, occasional findings may emerge, requiring diagnostic investigations such as bronchoscopy and interventional pulmonology procedures. Therefore, in such a delicate pathological condition, such as COVID-19, the need to perform bronchoscopy and interventional pulmonology procedures, minimizing the risk of viral transmission and ensuring necessary assistance, represents a great challenge for pulmonologists. In this article authors describe, for the first time in literature, a rare case of endobronchial hamartoma, radically resected using a single use bronchoscope, in a young female patient hospitalized for symptomatic COVID-19.

scholarly journals Lung disease recalling paraseptal emphysema in a patient with Goltz syndrome

2016 ◽  
Vol 11 ◽  
Author(s):  
Rosaria Cortese ◽  
Salvatore Savasta ◽  
Silvia Di Stasi ◽  
Tiziana Boggini ◽  
Chiara Trabatti ◽  
...  
Keyword(s):  
Lung Function ◽  
Lung Disease ◽  
Female Patient ◽  
Genetic Disorder ◽  
Lung Parenchyma ◽  
Pulmonary Involvement ◽  
Young Female ◽  
Case Presentation ◽  
Goltz Syndrome ◽  
First Time

Background: Goltz syndrome is a rare, genetic disorder mainly occurring in female patients. Case presentation: The case presented here is, to the best of our knowledge, the first description of the occurrence of lung parenchymal alterations in a young female patient affected by Goltz syndrome. Although pulmonary involvement is not known in patients affected by X-linked Goltz syndrome, the case here described is related to the even rarer autosomal form of the disease, as in this case. It is thus conceivable that in such different genetic setting the involvement of lung parenchyma may be unveiled through atypical emphysematous lesions. Conclusion: This report suggested - for the first time time - a rationale for a lung function and imaging screening in patients affected by Goltz syndrome at least in its autosomal form.

scholarly journals Mineralogy and Geochemistry of Ultramafic Rocks from Rachoni Magnesite Mine, Gerakini (Chalkidiki, Northern Greece)

Minerals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 934
Author(s):  
Evangelos Tzamos ◽  
Micol Bussolesi ◽  
Giovanni Grieco ◽  
Pietro Marescotti ◽  
Laura Crispini ◽  
...  
Keyword(s):  
Raw Materials ◽  
Mining Area ◽  
Ultramafic Rocks ◽  
Northern Greece ◽  
Icp Ms ◽  
Time In Literature ◽  
History Of ◽  
First Time ◽  
The Eu

The importance of magnesite for the EU economy and industry is very high, making the understanding of their genesis for the exploration for new deposits a priority for the raw materials scientific community. In this direction, the study of the magnesite-hosting ultramafic rocks can be proved very useful. For the present study, ultramafic rock samples were collected from the magnesite ore-hosting ophiolite of the Gerakini mining area (Chalkidiki, Greece) to investigate the consecutive alteration events of the rocks which led to the metallogenesis of the significant magnesite ores of the area. All samples were subjected to a series of analytical methods for the determination of their mineralogical and geochemical characteristics: optical microscopy, XRD, SEM, EMPA, ICP–MS/OES and CIPW normalization. The results of these analyses revealed that the ultramafic rocks of the area have not only all been subjected to serpentinization, but these rocks have also undergone carbonation, silification and clay alteration. The latter events are attributed to the circulation of CO2-rich fluids responsible for the formation of the magnesite ores and locally, the further alteration of the serpentinites into listvenites. The current mineralogy of these rocks was found to be linked to one or more alteration event that took place, thus a significant contribution to the metallo- and petrogenetic history of the Gerakini ophiolite has been made. Furthermore, for the first time in literature, Fe inclusions in olivines from Greece were reported.

A novel MADM approach to the ground-handling agent selection problem in B2B markets

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Mahmut Bakır ◽  
Emircan Özdemir ◽  
Şahap Akan
Keyword(s):  
Airline Industry ◽  
Multiple Attribute Decision Making ◽  
Content Type ◽  
B2b Marketing ◽  
Multiple Attribute ◽  
Time In Literature ◽  
Agent Selection ◽  
Ground Handling ◽  
First Time

PurposeGround-handling services are important for effective aircraft operations in the air transportation system. Airlines often outsource these services to ground-handling agents through business-to-business (B2B) marketing decisions. Therefore, this paper aims to address the problem of ground-handling agent selection in the airline industry.Design/methodology/approachA real-world case study was carried out to demonstrate the applicability of the integrated best worst method and fuzzy multi-attribute ideal real comparative analysis (F-MAIRCA) approach to solve ground-handling agent selection problems under uncertainty and imprecision. A two-stage sensitivity analysis was also conducted to ensure the credibility and validity of the application.FindingsIn the weighting stage, “Quality” was determined as the most important criterion in terms of supplier performance. With regard to the performance of the ground-handling agents, A2 was found as the optimal supplier in terms of both credibility and validity.Practical implicationsThis study enumerated several criteria that ground-handling agents must meet in order to effectively supply services for the airlines. In addition, this study provides a novel framework from which managers can gain additional benefits from their businesses. Finally, it is concluded that this approach will help airline managers quantitatively in choosing the most appropriate ground-handling agent.Originality/valueThe contributions of this study to the existing literature are twofold. First, we propose a novel multiple attribute decision-making approach to address the problem of supplier selection for airlines under uncertainty and imprecision. Second, the selection of ground-handling agents from the B2B perspective is addressed for the first time in literature.

scholarly journals Pulmonary multiple cystic lesions in a patient with Behçet’s syndrome

Reumatismo ◽  
2019 ◽  
Vol 71 (2) ◽  
pp. 103-104
Author(s):  
M.E. Tezcan ◽  
B. Isci
Keyword(s):  
Pulmonary Involvement ◽  
Behçet’S Syndrome ◽  
Cystic Lesions ◽  
Computerised Tomography ◽  
Behçet's Syndrome ◽  
Time In Literature ◽  
Behcet’S Syndrome ◽  
First Time ◽  
Behcet's Syndrome

Pulmonary involvement, mainly originating from vasculitis, is one of the features of Behçet’s syndrome (BS). We describe, for the first time in literature, computerised tomography images of a male BS patient with multiple pulmonary cystic lesions possibly originated from vasculitis or bronchiolar stenosis.

Multiobjective Collaborative Robust Optimization With Interval Uncertainty and Interdisciplinary Uncertainty Propagation

2008 ◽  
Vol 130 (8) ◽  
Author(s):  
M. Li ◽  
S. Azarm
Keyword(s):  
Robust Optimization ◽  
Probability Distributions ◽  
Uncertainty Propagation ◽  
Multiple Objectives ◽  
Interval Uncertainty ◽  
Optimization Approach ◽  
Solution Approach ◽  
Time In Literature ◽  
Collaborative Robust Optimization ◽  
First Time

We present a new solution approach for multidisciplinary design optimization (MDO) problems that, for the first time in literature, has all of the following characteristics: Each discipline has multiple objectives and constraints with mixed continuous-discrete variables; uncertainty exists in parameters and as a result, uncertainty propagation exists within and across disciplines; probability distributions of uncertain parameters are not available but their interval of uncertainty is known; and disciplines can be fully (two-way) coupled. The proposed multiobjective collaborative robust optimization (McRO) approach uses a multiobjective genetic algorithm as an optimizer. McRO obtains solutions that are as best as possible in a multiobjective and multidisciplinary sense. Moreover, for McRO solutions, the variation of objective and/or constraint functions can be kept within an acceptable range. McRO includes a technique for interdisciplinary uncertainty propagation. The approach can be used for robust optimization of MDO problems with multiple objectives, or constraints, or both together at system and subsystem levels. Results from an application of McRO to a numerical and an engineering example are presented. It is concluded that McRO can solve fully coupled MDO problems with interval uncertainty and obtain solutions that are comparable to a single-disciplinary robust optimization approach.

The role of miR-29 in pulmonary fibrosis

2015 ◽  
Vol 93 (2) ◽  
pp. 109-118 ◽  
Author(s):  
Leah Cushing ◽  
Pingping Kuang ◽  
Jining Lü
Keyword(s):  
Pulmonary Fibrosis ◽  
Epithelial Mesenchymal Transition ◽  
Pathological Condition ◽  
Lung Parenchyma ◽  
Interstitial Lung Diseases ◽  
Toxic Substances ◽  
Chronic Infections ◽  
Mesenchymal Transition

Pulmonary fibrosis is a pathological condition in which lungs become scarred due to the excess extracellular matrix (ECM) deposition and structural alterations in the interstitium of lung parenchyma. Many patients with interstitial lung diseases (ILDs) caused by long-term exposure to toxic substances, chronic infections, or autoimmune responses develop fibrosis. Etiologies for many ILDs are unknown, such as idiopathic pulmonary fibrosis (IPF), a devastating, relentless form of pulmonary fibrosis with a median survival of 2–3 years. Despite several decades of research, factors that initiate and sustain the fibrotic response in lungs remain unclear and there is no effective treatment to block progression of fibrosis. Here we summarize recent findings on the antifibrotic activity of miR-29, a small noncoding regulatory RNA, in the pathogenesis of fibrosis by regulating ECM production and deposition, and epithelial–mesenchymal transition (EMT). We also describe interactions of miR-29 with multiple profibrotic and inflammatory pathways. Finally, we review the antifibrotic activity of miR-29 in animal models of fibrosis and highlight miR-29 as a promising therapeutic reagent or target for the treatment of pulmonary fibrosis.

Bilateral morgagni hernia in a case of Weill-Marchesani syndrome-a rare association

2017 ◽  
Vol 5 (6) ◽  
pp. 2790
Author(s):  
Ravindran Chetambath ◽  
Jabeed Parengal ◽  
Mohammed Aslam ◽  
Sanjeev Shivashankaran
Keyword(s):  
Female Patient ◽  
Morgagni Hernia ◽  
Rare Association ◽  
Morphometric Features ◽  
Time In Literature ◽  
First Time ◽  
Diaphragmatic Hernias

Morgagni hernia constitutes only about 2% of all diaphragmatic hernias and bilateral Morgagni hernia is extremely rare. Here we present a 75 year old female patient with morphometric features of Weill-Marchesani syndrome who has bilateral Morgagni hernia. This association is reported for the first time in literature.

Harnessing low energy photons (635 nm) for the production of H2O2 using upconversion nanohybrid photocatalysts

2016 ◽  
Vol 9 (3) ◽  
pp. 1063-1073 ◽  
Author(s):  
Hyoung-il Kim ◽  
Oh Seok Kwon ◽  
Sujeong Kim ◽  
Wonyong Choi ◽  
Jae-Hong Kim
Keyword(s):  
Hydrogen Peroxide ◽  
Low Energy ◽  
Time In Literature ◽  
First Time ◽  
Photocatalytic Synthesis ◽  
Triplet Triplet Annihilation

This study demonstrates, for the first time in literature, in situ photocatalytic synthesis of hydrogen peroxide (H2O2) through sensitized triplet–triplet annihilation (TTA) upconversion (UC) of low-energy, sub-bandgap photons.

scholarly journals A Revision of the Coccidia Parasitic in Man

Parasitology ◽  
1919 ◽  
Vol 11 (2) ◽  
pp. 147-197 ◽  
Author(s):  
Clifford Dobell
Keyword(s):  
Small Intestine ◽  
Geographical Distribution ◽  
Human Liver ◽  
Near East ◽  
Pathological Condition ◽  
Distinct Species ◽  
Good Evidence ◽  
The Other ◽  
New Form ◽  
First Time

From a study of the organisms themselves, so far as this has been possible, and from an analysis of all accessible records relating to them, I conclude that there are four distinct species of coccidia which may parasitize man. These are: (1) Isospora hominis Rivolta, 1878 (emend.), discovered by Kjellberg in 1860. and recently investigated by Wenyon; (2) Eimeria wenyoni n.sp., a form discovered in 1915 by Wenyon; (3) Eimeria oxyspora n.sp., another new form, here described for the first time; (4) an undetermined species of Eimeria (?) which was discovered by Gubler in 1858. This last inhabits the human liver, whilst the three others probably live in the small intestine. Probably some seventy cases of infection with the Isospora have now been seen, mostly in persons who have been in the Near East; but the other parasites appear to be extremely rare, and little is known concerning their probable geographical distribution.All these parasites are probably peculiar to man. There is no evidence that any of them is or can be parasitic in any other host. The prevailing belief that the coccidia of man are identical with those of rabbits, cats, or dogs, is therefore unfounded. Furthermore, there is as yet no good evidence to show that man may harbour any species of coccidia other than the four just enumerated. All these forms, however, require fuller investigation. They are here briefly and incompletely described from the data at present available.There is at present no proof that the coccidia of man—with the probable exception of the species occurring in the liver—can produce a clinically recognizable pathological condition of “coccidiosis”: and as yet no method of treatment which will eradicate an infection with any species has been discovered.

scholarly journals Interactions of Oxygen at High Pressure and Radiation in Drosophila

1966 ◽  
Vol 49 (3) ◽  
pp. 537-549 ◽  
Author(s):  
J.J. Thomas ◽  
R.C. Baxter ◽  
W.O. Fenn
Keyword(s):  
High Pressure ◽  
Life Span ◽  
Young Male ◽  
Fruit Fly ◽  
Young Female ◽  
Acute Effects ◽  
Irreversible Effects ◽  
X Irradiation ◽  
Effects Of Radiation ◽  
First Time

Oxygen at high pressure (OHP) and X-irradiation can interact in the fruit fly Drosophila melanogaster to potentiate toxic actions characteristic of one agent alone. 1000 kvp X-irradiation in doses of 30, 60, and 75 kr accelerated the acute immobilization of young male Drosophila by oxygen at 7.8 atm, up to rates twice that observed with such oxygen pressure alone. X-irradiation alone in these dosages did not acutely immobilize the Drosophila. X-irradiation during exposure to 7.8 atm pO2 was more effective and consistent in producing this potentiation than was X-irradiation that preceded exposure to OHP. Acute OHP toxicity in young female Drosophila was not potentiated by 75 kr of X-irradiation. On the other hand, shortening of the life span of young male Drosophila by the above doses of X-irradiation was augmented significantly by a concurrent 40 min exposure to OHP (which alone did not significantly decrease life span). This shows, for the first time, that oxygen can affect not only the acute effects of radiation, but also the residual irreversible effects indicated by the life span shortening.

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