QUALITY OF LIFE IN PATIENTS WITH THALASSEMIA MAJOR AND INTERMEDIA IN KERMAN-IRAN (I.R.)

Thalassemia is the most common hemoglobin disorder in the world and thalassemia major and intermedia stand among the most severe forms. Due to recent improvements in treatment, patients with thalassemia have longer life expectancies; hence it is of utmost importance to pay careful attention to their quality of life together with life expectancy. This study was conducted to assess the quality of life in patients with thalassemia and also to compare it between thalassemia major and intermedia. In this cross-sectional study, patients who referred for blood transfusion or follow-up visits were evaluated for their quality of life (QOL). Short Form-36 questionnaire was applied to evaluate QOL. In this study, 308 patients with a mean age of 22.95±4.82 years were evaluated. The scores of QOL were regarded as moderate in eight domains under evaluation; the least score was given to General Health (53.05±16.96) whereas the highest score was given to Physical Functioning (67.95±22.68). The QOL in the patients with thalassemia major was better than those with thalassemia intermedia regarding Physical Functioning and Role Limitation Emotional domains. Compared to injecting chelators, patients who received oral chelators showed to have a better QOL considering Social Functioning and Mental Health domain. The patients under study didn’t have a satisfying QOL ; the QOL of patients with thalassemia major was better than that of patients with thalassemia intermedia in only 2 domains of sf-36(Physical Functioning & Role limitation-Emotional). It is then essential that experts pay proper attention to improve QOL among patients.

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Quality of life in multiple sclerosis: The differential impact of motor and cognitive fatigue

Multiple Sclerosis Journal - Experimental Translational and Clinical ◽

10.1177/2055217321996040 ◽

2021 ◽

Vol 7 (1) ◽

pp. 205521732199604

Author(s):

Sabina David Ruban ◽

Claudia Christina Hilt ◽

Thor Petersen

Keyword(s):

Quality Of Life ◽

Multiple Sclerosis ◽

Short Form ◽

Cross Sectional Study ◽

University Hospital ◽

Cognitive Fatigue ◽

Cross Sectional ◽

Impact Scale ◽

Assessment And Treatment

Background Multiple sclerosis is a chronic disease leading to reduced quality of life. Objectives To investigate whether motor and cognitive fatigue impact differently on aspects of quality of life among patients with multiple sclerosis, independently from bodily disability. Methods 79 patients with multiple sclerosis from Aalborg University Hospital, Denmark were included in an observational, cross-sectional study. Each subject completed two separate questionnaires regarding fatigue (Fatigue Scale for Motor and Cognitive Functions and Modified Fatigue Impact Scale) and one regarding quality of life (Short Form 36). Disability was measured with the Expanded Disability Status Scale (EDSS)-scores obtained from patient records. Results All fatigue scores were significantly correlated to all areas of quality of life (p < 0,05). This remained significant after adjustment for age, disease duration and EDSS-score. When looking at each type of fatigue separately, cognitive fatigue correlated mainly with mental health aspects of quality of life and motor fatigue with physical health areas of quality of life. Conclusion Increased motor and cognitive fatigue lead to a differential reduction in physical and mental quality of life, independently of bodily disability. This underlines the importance of proper assessment and treatment of fatigue among patients with multiple sclerosis.

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Predictors of quality of life among patients on dialysis in southern Brazil

Sao Paulo Medical Journal ◽

10.1590/s1516-31802008000500002 ◽

2008 ◽

Vol 126 (5) ◽

pp. 252-256 ◽

Cited By ~ 25

Author(s):

Maristela Bohlke ◽

Diego Leite Nunes ◽

Stela Scaglioni Marini ◽

Cleison Kitamura ◽

Marcia Andrade ◽

...

Keyword(s):

Quality Of Life ◽

Peritoneal Dialysis ◽

Short Form ◽

Outcome Measurement ◽

Cross Sectional Study ◽

Southern Brazil ◽

Cross Sectional ◽

Sf 36 ◽

Dialysis Facilities

CONTEXT AND OBJECTIVE: Quality of life (QoL) is considered important as an outcome measurement, especially for long-term diseases such as chronic renal failure. The present study searched for predictors of QoL in a sample of patients undergoing dialysis in southern Brazil. DESIGN AND SETTING: This was a cross-sectional study developed in three southern Brazilian dialysis facilities. METHODS: Health-related QoL of patients on hemodialysis or peritoneal dialysis was measured using the generic Short Form-36 (SF-36) health survey questionnaire. The results were correlated with sociodemographic, clinical and laboratory variables. The analysis was adjusted through multiple linear regression. RESULTS: A total of 140 patients were assessed: 94 on hemodialysis and 46 on peritoneal dialysis. The mean age was 54.2 ± 15.4 years, 48% were men and 76% were white. The predictors of higher (better) physical component summary in SF-36 were: younger age (β-0.16; 95% confidence interval, CI: -0.27 to -0.05), shorter time on dialysis (β-0.06; 95% CI: -0.09 to -0.02) and lower Khan comorbidity-age index (β 5.16; 95% CI: 1.7-8.6). The predictors of higher mental component summary were: being employed (β 8.4; 95% CI: 1.7-15.1), being married or having a marriage-like relationship (β 4.56; 95% CI: 0.9-8.2), being on peritoneal dialysis (β 4.9; 95% CI: 0.9-8.8) and not having high blood pressure (β 3.9; 95% CI: 0.3-7.6). CONCLUSIONS: Age, comorbidity and length of time on dialysis were the main predictors of physical QoL, whereas socioeconomic issues especially determined mental QoL.

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Social support, functional outcome and quality of life among stroke survivors in an urban area

Journal of Pacific Rim Psychology ◽

10.1017/prp.2019.2 ◽

2019 ◽

Vol 13 ◽

Author(s):

Nipaporn Butsing ◽

Mathuros Tipayamongkholgul ◽

Disya Ratanakorn ◽

Nawarat Suwannapong ◽

Kanitta Bundhamcharoen

Keyword(s):

Quality Of Life ◽

Social Support ◽

Functional Outcome ◽

Short Form ◽

Cross Sectional Study ◽

Linear Regression Method ◽

Stroke Survivors ◽

Cross Sectional ◽

The Mean

AbstractSophisticated medical technologies can prolong a stroke patient’s life but not always their quality of life (QoL) due to poor functional outcomes. Social support can theoretically assist a patient’s adaptation to life after stroke and improve their QoL, but existing findings are inconclusive. This inconclusiveness is especially found in large cities where family and social bonding can be scarce. We conducted a hospital-based, cross-sectional study among 358 stroke patients to identify the effects of social support and functional outcome on QoL and its domains. The study took place in Bangkok, Thailand between July and December 2016. Data were collected by personal interview using a structured questionnaire that included the Short-Form WHO Quality of Life Instrument (WHOQOL-BREF) and by review of medical records. A hierarchical linear regression method was used to analyze data. The mean age of stroke respondents was 66.0 years (SD 13.5 years), and half were male. The mean total QoL score for patients was 68.6 (SD 15.2). Hierarchical multiple regression analysis found emotional support significantly impacted QoL in every domain (ps < .05) when all included variables were controlled for. To improve the quality of life among stroke survivors, health personnel and family members should provide not only physical assistance but also psychological support.

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Quality of life and stress in caregivers of drug-addicted people

Acta Paulista de Enfermagem ◽

10.1590/s0103-21002012000900002 ◽

2012 ◽

Vol 25 (spe2) ◽

pp. 7-12

Author(s):

Samira Reschetti Marcon ◽

Elizete Aparecida Rubira ◽

Mariano Martinez Espinosa ◽

Angélica Belasco ◽

Dulce Aparecida Barbosa

Keyword(s):

Quality Of Life ◽

Short Form ◽

Psychosocial Care ◽

Cross Sectional Study ◽

Depression Symptoms ◽

Cross Sectional ◽

Mato Grosso ◽

Burden Scale ◽

Emotional Aspects

OBJECTIVE: To evaluate quality of life and presence of stress in caregivers of drug-addicted people. METHODS: This cross-sectional study was carried out at four Psychosocial Care Centers in Mato Grosso. Demographic and quality of life data were collected for 109 caregivers using the Medical Outcomes Study 36 - Item Short-form, depression symptoms (Beck Depression Inventory) and stress of caregivers (Caregiver Burden Scale). RESULTS: Of 109 caregivers, 55.9% were mothers with a mean age of 47.66 years; 23.8% had depressive symptoms. The SF36 scores most compromised were emotional aspects, vitality, pain and mental health. Mean stress among caregivers was 2.24. A significant correlation in quality of life, depression and stress of caregivers was seen. CONCLUSION: Findings confirmed that quality of life is compromised and stress is high among caregivers, highlighting the need for providing emotional support.

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Stigma and quality of life for patients with facial dystonia: a cross-sectional study

10.21203/rs.3.rs-1184753/v1 ◽

2022 ◽

Author(s):

MING YI ◽

Jing LI ◽

Gang LIU ◽

Weixi ZHANG ◽

Ying WANG ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Short Form ◽

Cross Sectional Study ◽

Control Group ◽

Hamilton Depression Scale ◽

Sectional Study ◽

Cross Sectional ◽

Facial Dystonia

Abstract Background Facial appearance and expressions influence social interaction. However, few studies have reported on the stigma associated with spasms from facial dystonia. This study investigated the stigma and quality of life for these patients. Methods This cross-sectional study included 90 patients with facial dystonia (hemifacial spasm [HFS], blepharospasm [BSP], and blepharospasm-oromandibular dystonia [BOD]; 30 patients per group) and 30 individuals without dystonia (control group) from October 2019 to November 2020. All participants underwent stigma, quality of life, and mental health evaluations using seven questions related to stigma, the 36-item Short Form Health Survey, the 14-item version of the Hamilton Anxiety Scale (HAMA), and the 24-item version of the Hamilton Depression Scale. Results Nineteen patients (21.11%) felt stigmatized. Patients with BPS and HFS had more difficulty finding a job and were more susceptible to discrimination than healthy individuals. The role-physical and social function scores were significantly lower in the dystonia groups than in the control group. The vitality score of the BPS group and the mental health scores in the BPS and BOD groups were significantly less than those of the control group. The HAMA scores in the BPS and BOD groups were significantly higher than in the control group. Regression analysis demonstrated that the disease course influenced depression. Conclusion Enacted stigma from a negative public attitude may be the main factor triggering stigma in patients with facial dystonia, with detrimental effects on psychosocial outcomes, including social rights, quality of life, and mood.

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Assessment of quality of life of stroke survivors in a rural area of North Kerala, India

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20170769 ◽

2017 ◽

Vol 4 (3) ◽

pp. 841 ◽

Cited By ~ 1

Author(s):

Priya Chandran ◽

Dhanya Shenoy ◽

Jayakrishnan Thavody ◽

Lilabi M. P.

Keyword(s):

Quality Of Life ◽

Rural Area ◽

Short Form ◽

Significant Proportion ◽

Population Based ◽

Stroke Survivors ◽

Cross Sectional ◽

Sf 36 ◽

Role Limitation

Background: With increase in prevalence of stroke and life expectancy the quality of life of stroke survivors assumes importance. Despite advances in diagnosis and treatment of cerebrovascular accidents the survivors continue to experience low Quality of life (QoL) especially in developing countries. The objective of this study was to assess the quality of life among stroke survivors and the prevalence of depression among them. Methods: Cross-sectional population based study was conducted in a rural area of North Kerala. Stoke survivors were interviewed at home to assess the quality of life and depression status. QOL was assessed using the Medical Outcomes 36-Item Short-Form Health Survey (SF-36), functional status using the modified barthel index (MBI), and mood using the Beck’s Depression Inventory (BDI).Results: A total of 40 patients (65.5% men, mean age 70.58±10.7 years) were interviewed. The mean MBI was 55.25±2.79, and the prevalence of unrecognized depression was 90%. 95 percent of patients needed varying degrees of care for their activities of daily living. The SF-36 scores of the patients were considerably lower than that to that of the general population especially in the areas of role limitation and physical functioning. Depression was more among older subjects and Depressed patients had lower MBI scoresConclusions: A significant proportion of stroke survivors continue to face limitations in their physical activities. In addition, majority have unrecognised depression that affects their QOL adversely.

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Symptom, Adopting Healthy Life Style, and Quality of Life in Patients with Liver Cirrhosis: A Cross-Sectional Study

10.21203/rs.3.rs-68412/v1 ◽

2020 ◽

Author(s):

Myung Kyung Lee ◽

Woo Jin CHUNG

Keyword(s):

Quality Of Life ◽

Liver Cirrhosis ◽

Fruits And Vegetables ◽

Short Form ◽

Cross Sectional Study ◽

Sectional Study ◽

Quadrant Pain ◽

Cross Sectional ◽

Intensity Of Exercise

Abstract Background: Previous studies have not considered a broad range of symptoms and the association with healthy behavior and quality of life of patients with liver cirrhosis. Objectives: The purposes of the study were to examine the association of symptom with adopting exercise and consuming fruits and vegetables, and to identify factors associated with quality of life in patients with liver cirrhosis.Methods: This cross-sectional study enrolled 91 consecutive patients with liver cirrhosis in one tertiary general hospital in South Korea between February 2016 and January 2017. Each study participant completed a self-administered questionnaire that measured symptom, stage-of-change in performing exercise and consumption of fruits and vegetables, and the Korean version of the 36-item Short-Form Health Survey. Multivariate logistic regression analysis and multiple regression models was used respectively to examine the association of each symptom with engaging in exercise and increasing consumption of fruits and vegetables and to evaluate factors affecting quality of life.Results: Experiencing nausea was associated with increased intensity of exercise but experiencing shortness of breath was associated with decreased intensity of exercise. Experiencing right upper quadrant pain was associated with increased consumption of fruits and vegetables and muscle cramps, anorexia, right upper quadrant pain and body pain, itching, ascites or edema, bruising, and change in appearance negatively affected quality of life.Conclusions: The results suggest that the types of symptoms experienced by a patient with liver cirrhosis hinder or promote the patient’s adoption of exercise and dietary behavior. Experiencing symptoms may negatively affect quality of life. Caregivers should provide supportive care to patients with liver cirrhosis, which includes assessing and managing symptoms to improve quality of life.

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The Quality of Life of Tuberculosis Patients at Witbank TB Hospital, South Africa: A Cross-sectional Study

10.21203/rs.3.rs-100178/v1 ◽

2020 ◽

Author(s):

Rejoice Tlangelani Mashaba ◽

Fezile Khumalo ◽

Andy Beke

Keyword(s):

Quality Of Life ◽

South Africa ◽

Short Form ◽

Family Members ◽

Cross Sectional Study ◽

Mental Wellbeing ◽

Cross Sectional ◽

Explanatory Variables ◽

Co Morbidity

Abstract Background: The quality of life (QoL) of tuberculosis (TB) patients may predict treatment outcomes. Little is known about the QoL of patients with TB and Human immunodeficiency virus (HIV) co-morbidity, especially in South African settings. We investigate the QoL of TB patients with and without HIV at the Witbank TB Hospital in Mpumalanga Province, South Africa. Methods: In a cross-sectional analytical study, 124 patients with confirmed TB, with or without HIV co-infection, were recruited from September 2018 to October 2018. Trained interviewers conducted face-to-face interviews with participants, helping them to complete a standardized short form-12 (SF-12) QoL questionnaire. The data were analyzed using SPSS and SAS software. Differences between groups were quantified using t-test. Logistic regression analysis identified explanatory variables predicting mental (MCS) health and physical (PCS) health. Results: For all sub-scales of the SF-12 instrument, Cronbach’s alpha > 0.8 demonstrating high internal consistency. Patients with TB/HIV co-morbidity had lower scores in all dimensions (p<0.05), indicating poor QoL compared to TB patients without HIV. In multivariate analysis, the family size was predictive of physical health QoL. TB patients who were staying in a household with more than four family members were 2.12 times more likely to have better QoL compared to TB patients living in households with fewer than four family members, OR= 2.33 (95% CI: 1.12 to 4.98); p<0.05). Conclusions: Patients who are co-infected with TB and HIV, in this setting, have poorer QoL than patients who are only infected with TB. Our results support the development of strategies to improve QoL that consider the physical and mental wellbeing of TB/HIV co-infected patients.

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Health-related quality of life predictors during medical residency in a random, stratified sample of residents

Brazilian Journal of Psychiatry ◽

10.1590/s1516-44462009000200007 ◽

2009 ◽

Vol 31 (2) ◽

pp. 119-124 ◽

Cited By ~ 13

Author(s):

Paula Costa Mosca Macedo ◽

Vanessa de Albuquerque Cítero ◽

Simone Schenkman ◽

Maria Cezira Fantini Nogueira-Martins ◽

Mauro Batista Morais ◽

...

Keyword(s):

Quality Of Life ◽

Short Form ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Cross Sectional Study ◽

First Year ◽

Cross Sectional ◽

Critical Patients ◽

Almost All

OBJECTIVE: To evaluate the quality of life during the first three years of training and identify its association with sociodemographicoccupational characteristics, leisure time and health habits. METHOD: A cross-sectional study with a random sample of 128 residents stratified by year of training was conducted. The Medical Outcome Study -short form 36 was administered. Mann-Whitney tests were carried out to compare percentile distributions of the eight quality of life domains, according to sociodemographic variables, and a multiple linear regression analysis was performed, followed by a validity checking for the resulting models. RESULTS: The physical component presented higher quality of life medians than the mental component. Comparisons between the three years showed that in almost all domains the quality of life scores of the second year residents were higher than the first year residents (p < 0.01). The mental component scores remained high for third year residents (p < 0.01). Predictors of higher quality of life were: second or third year of residency, satisfaction with the training program, sufficient time for leisure, and care of critical patients for less than 30 hours per week. CONCLUSION: The mental component of quality of life was the most impaired component, indicating the importance of caring for residents' mental health, especially during their first year and when they are overloaded with critical patients.

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