scholarly journals Determinants of adherence to antiretroviral drugs among people living with HIV/AIDS in the Ife-Ijesa zone of Osun state, Nigeria

Author(s):  
Muhammed O. Afolabi ◽  
Kayode T. Ijadunola ◽  
Adesegun O. Fatusi ◽  
Olayinka A. Olasode

Background: The advent of antiretroviral (ARV) drugs has transformed HIV/AIDS into a chronic manageable disease and strict adherence is required for the medication to be effective. However, factors influencing adherence to ARV therapy (ART) vary from country to country.Method: 120 subjects who received ARV drugs at a federal government-designated ART site located within the Obafemi Awolowo University Teaching Hospital complex, (OAUTHC), Ile-Ife, and a community-based non-governmental organisation, Living Hope Care (LIHOC), Ilesa, from February to May 2006 were serially recruited and studied. Relevant data were collected using an interviewer-administered, patient medication adherence questionnaire. Focus group discussions were also held among the subjects to further elicit qualitative information on factors influencing adherence to ART.Results: The age of participants ranged from 21 to 65 years with a mean age of 40.2 + 10.3 years. Participants had been on ARV drugs for a period ranging between three and 60 months. The overall adherence rate in the study population was 44%. 66% of participants who accessed ARV drugs from LIHOC, Ilesa, had good adherence while only 14% of participants who accessed ARV drugs from OAUTHC, Ile-Ife, had good adherence. Participants with good adherence did not pay funds for the preliminary ARV eligibility investigations and they were also offered regular adherence counselling. These facilities were barely available in the group with poor adherence. Demographic factors such as age, gender and marital status did not seem to have any significant association with adherence level (p > 0.05).Conclusion: The level of adherence was high in a cohort of PLWHA accessing ARV drugs in Ilesa while it was low among PLWHA receiving ART in Ife. The most important reasons for this difference were lack of funds for investigations and poor psycho-social counselling.

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Tri Nurhudi Sasono

Abstract : Indicator of the health welfare through Sustanable Development Goals (SDGs) is to reduce the incidence of HIV-AIDS, decrease the rate of the epidemic and maintain the quality of life of people living with HIV-AIDS (PLWHA). Trend cases of HIV-AIDS is the most recent spread among people, especially housewives. In Malang until 2015 found 278 Housewife of 409 cases of AIDS. The prevalence of HIV-AIDS in Malang Regency is ranked second after Surabaya city in East Java. For the importance of public participation and citizen care AIDS Cahaya Care Turen take responsibility for the condition. Determination Rule Goverment number 2 2015 year on the Participation of the community response to HIV-AIDS in Malang as a legal rule. Concerned Citizens activities AIDS (WPA). WPA Cahaya Care Turen is increases HIV risk and quality of life PLWHA. The purpose of this study was to determine the role of Citizens AIDS Cahaya Care Quality of Care Turen against people living with HIV in Puskesmas Turen Malang. The study design using a quasi-experimental, with purposive sampling using a sampling technique. Total number of research subjects 23. Based on test results obtained with the Wilcoxon p value <0.005, which means that there is a significant difference before and after PLWHA joining participated in the WPA Cahaya Care Turen. The conclusion of this study is WPA activities involving people living with HIV and at risk groups can optimize compliance with antiretroviral drugs that have an impact on improving the quality of life of PLHIV. Suggestions in this research is done WPA Program activities are structured and ongoing cross-sector in order to improve the quality of life and empower PLWHA.Keywords : WPA Cahaya Care Turen, Quality of life, PLWHA Abstrak : Salah satu indikator kesejahteraan kesehatan melalui Sustanable Development Goals (SDGs) adalah menekan angka kejadian HIV-AIDS, menurunkan laju epidemik dan mempertahankan kualitas hidup Orang dengan HIV-AIDS (ODHA). Trend kasus HIV-AIDS terkini terbanyak adalah menjangkit dikalangan masyarakat khususnya pada ibu rumah tangga. Kabupaten Malang sampai dengan tahun 2015 ditemukan 278 Ibu Rumah Tangga dari 409 kasus AIDS. Prevalensi HIV-AIDS di Kabupaten Malang ini merupakan peringkat kedua di Jawa Timur setelah Kota Surabaya. Untuk itu pentingnya peran serta masyarakat dan warga peduli AIDS Cahaya Care Turen ikut bertanggung jawab terhadap kondisi tersebut. Penetapan Peraturan Bupati Malang no.2 th.2015 tentang Peran serta masyarakat penanggulangan HIV-AIDS di Kabupaten Malang diharapkan dapat mengurangi risiko penularan HIV dan meningkatkan kualitas hidup ODHA. Tujuan dari penelitian ini adalah untuk mengetahui Peran Warga Peduli AIDS Cahaya Care Turen terhadap Kualitas ODHA Di Wilayah Kerja Puskesmas Turen Kabupaten Malang. Desain penelitian menggunakan quasi eksperimen, dengan teknik sampling menggunakan purposive sampling. Jumlah subyek penelitian sejumlah 23. Berdasarkan hasil uji dengan Wilcoxon didapatkan nilai p value < 0.005 yang berarti bahwa terdapat perbedaan bermakna sebelum dan sesudah ODHA bergabung mengikuti kegiatan WPA Cahaya Care Turen. Kesimpulan dalam penelitian ini adalah kegiatan WPA dengan melibatkan ODHA dan kelompok beresiko dapat mengoptimalkan kepatuhan obat ART sehingga berdampak terhadap peningkatan kualitas hidup ODHA. Saran dalam penelitian ini adalah dilakukannya Program kegiatan WPA yang terstruktur dan berkesinambungan lintas sektor guna meningkatkan kualitas hidup dan memberdayakan ODHA.     Kata kunci : WPA Cahaya Care Turen, kualitas hidup, ODHA


2019 ◽  
Vol 53 (5) ◽  
Author(s):  
Retno Palupi ◽  
Agung Sosiawan ◽  
Gilang Rasuna Sabdho Wening ◽  
Aulia Ramadhani

Background. Human immunodeficiency viruses (HIV) / Acquired immunodeficiency syndrome (AIDS) is one of the most significant public health challenges in Surabaya, Indonesia where the greatest number of people living with HIV/AIDS (PLWHA) among key populations is in areas served by Sememi Public Health Center. HIV-infected persons have a greater risk for developing dental caries, such as salivary gland enlargement, and decreased salivary glands function. Given the fact that PLWHA are at high risk of dental caries, utilization of dental health service among PLWHA are still low. Objective. This study aims to know the factors influencing dental caries in HIV/AIDS patients.Methods. This is a descriptive, cross-sectional study conducted on 16 HIV-seropositive individuals. They were asked to complete a WHO questionnaire concerning basic oral health and quality of life. Dental caries was assessed using the Decayed, Missing, and Filled Teeth (DMFT) index. Whole stimulated saliva samples were also collected.Results. Nine out of 16 respondents had low salivary flow rate (56.3%). One patient had low DMF-T score (6.3%) and eight had high DMFT score (50%). Among seven respondents who had normal salivary flow rate (43.8%), two of whom had low DMFT score (12.5%) and five of whom had high DMFT score (31.3%).Conclusion. People living with HIV/AIDS have high DMFT and low salivary flow rate.


2019 ◽  
Author(s):  
Bereket Beyene Gebre

Abstract Abstract Objective: To assess the magnitude of alcohol use and factors among HIV/AIDS positive adults visiting ART clinic at Mizan Tep university Teaching Hospital (MTUTH), Southern Ethiopia from October 2017 to December 2017. Result: A total of 332 participants were enrolled in the study with the prevalence of alcohol use disorder (AUD) of 18.4%. Factors associated with alcohol use disorder were sex AOR=3.48 (95%CI: 1.27, 9.59), cigarette smoking AOR=5.12(95%CI:4.02,8.61), “Khat” chewing AOR=3.23(95%CI: 2.06,6.89),and CD4 count of 0-200 AOR = 19.49 (95% CI:1.74 ,218.4). Key words:-Magnitude, Alcohol use disorder, factors.


2020 ◽  
Author(s):  
Fatuma Degu ◽  
Yeneabat Birhanu ◽  
Abere Azagew

Abstract Background Sleep disturbance is the leading health problem in the era of HIV/AIDS. The exact cause of sleep disturbance was not well known, but it is related to HIV itself, antiretroviral drugs side effect, and other HIV related disorders. This study aimed to assess the prevalence of sleep disturbance and associated factors among adult people living with HIV/AIDS. Methods A cross-sectional study was conducted. A total of 419 study participants participated in the study. A systematic random sampling method was employed. An interviewer-administered a method of data collection with a chart review was used. Pittsburg Sleep Quality of Index for assessing sleep disturbance was used. A binary logistic regression was conducted. The variables having a p-value < 0.05 with 95% CI were used to declare an association. Results The prevalence of sleep disturbance was 36% (95% CI: 31–41%). The study revealed that being female (AOR = 3.45, 95% CI: 1.52–7.79), viral loads ≥ 1000 copies /ml (AOR = 6.88, 95% CI: 2.79–16.9), CD4 cell count < 200 cells/mm3 (AOR = 6.85, 95% CI: 2.42–19.39), WHO stage II and III(AOR = 4.29, 95%CI: 1.05–17.53), having anxiety (AOR = 10,95% CI: 4.21–23.9), having depression (AOR = 4.4, 95% CI: 1.95–10.1), having not a separated bedroom (AOR = 3.94, 95% CI: 1.86–8.36), and living alone (AOR = 6, 95% CI: 2.81–13.12) were found to be factors associated with sleep disturbance. Conclusion In this study, more than one - thirds of the study participants were developed sleep disturbance. Being female, low CD4 cell counts, viral load ≥ 1000copies/ml, WHO stage II and III, having depression and anxiety, living alone, and have not a separate bedroom have increased the experience of sleep disturbance.


Author(s):  
Asogwa, Eucharia Ijego ◽  
Obeagu, Emmanuel Ifeanyi ◽  
Ekine, Rupee Suoton ◽  
Asogwa, Okwudilichukwu Okwy ◽  
Amaeze, Augustine Amaeze ◽  
...  

The main aim of this study was to find out the effects of 6 weeks moderate intensity aerobic exercises on CD4 count, bone mineral density and weight of people living with HIV/AIDS in Alex-Ekwueme Federal University Teaching Hospital, Ebonyi State. The study adopted experimental research design. The study was carried out form year 2019-February 2020. The population of the study was 40 HIV/AIDS patients that attended HIV clinics at AE-FUTHA which formed the sample size after two subjects declined from the control group in the study. Simple random sampling technique was adopted for the study. Flowcytometery (Partec Cyflow counter) Germany, Heel Densitometer (X-rite 331C), and Omron BF 400 were the instrument used for data collection of CD4 counts, BMD and weight respectively. Mean, standard deviation and ANCOVA were used to analyze the data obtained.  The instruments were not validated because they are standard. The reliability coefficient obtained from the pilot study was 0.848, 0.835 and 0.994 for CD4, BMD and WEIGHT respectively. The major findings revealed that MIAE had positive effect on CD4 counts and BMD but negative effect on weight.


Author(s):  
C. P. Igweagu ◽  
O. H. Chime ◽  
O. C. Ekwueme

Background: The Acquired Immune – deficiency syndrome (AIDS) is a terminal illness caused by a retrovirus known as the Human Immune-deficiency virus (HIV). HIV/AIDS is a leading cause of death in sub-saharan Africa. Nigeria has the second largest HIV epidemic in the world and one of the highest rates of new infection in sub-Saharan Africa with 1.9 million people living HIV in 2018. Antiretroviral therapy (ART) has significantly reduced morbidity and mortality, prolonged life expectancy and improved quality of life among people living with HIV/AIDS infection (PLWHA). To be most effective ART requires a near perfect level of adherence. Poor adherence compromises treatment effectiveness, leading to treatment failure and development of drug resistance. Non-adherence is also characterized by increased morbidity, mortality and great economic loss. This study assessed the effect of health education on factors influencing adherence to ART among PLWHAs in Enugu State. Methodology: A health education intervention was carried out among 312 persons living with HIV/AIDS receiving ART in Enugu metropolis to improve their perception and adherence to antiretroviral therapy. A structured questionnaire was used to collect data from 312 people living with HIV/AIDS (156 each in the study and control groups), who were selected by multistage sampling. Subsequently, health education was conducted among the study group. Three months after this intervention its effects were assessed through a survey using the same structured questionnaires employed in the baseline survey. Results: Knowledge of supportive and limiting factors of adherence improved significantly among the study group than the controls post-intervention (P<0.001). The factors that facilitated adherence included follow-up visits, adequate information education/counseling and supportive relationships. The limiting factors were drug side-effects, forgetfulness, finance and travel time to clinic. Conclusion: Health education improved knowledge of supportive factors of ART adherence among PLWHAs in Enugu State, and this should be promoted.


Sign in / Sign up

Export Citation Format

Share Document