scholarly journals HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Erica Parker ◽  
Melinda A. Judge ◽  
Eusebio Macete ◽  
Tacilta Nhampossa ◽  
Jienchi Dorward ◽  
...  

Background: The burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to experience significant challenges resulting from high rates of morbidity, mortality and new infections. Hard-won lessons from programmes on the ground in ESA should be shared.Objectives: This report summarises relevant evidence and regional experts’ recommendations regarding challenges specific to ESA.Method: This commentary includes an in-depth review of relevant literature, progress against global goals and consensus opinion from experts.Results: Recommendations include priorities for essential research (surveillance data collection, key and vulnerable population education and testing, in-country testing trials and evidence-based support services to improve retention in care) as well as research that can accelerate progress towards the prevention of new infections and achieving ambitious global goals in ESA.Conclusion: The elimination of HIV in ESA will require continued investment, commitment to evidence-based programmes and persistence. Local research is critical to ensuring that responses in ESA are targeted, efficient and evaluated.

Author(s):  
Jonathan Mukwevho ◽  
Mpho Ngoepe ◽  
Patrick Ngulube

Providing access and usage are the reason for existence of memory institutions such as archive repositories. Despite the importance of the visibility and accessibility of public archive repositories, various scholars concur that these repositories in eastern and southern Africa are not known and are accessed by few people. This chapter utilises the concept of soft power as a framework to examine the visibility and accessibility of public archives repositories in South Africa. A quantitative research approach utilising questionnaires, interviews, content analysis and the observation of landmarks were employed as data collection tools. The findings revealed that collaboration, especially with civil societies, is a key for successful public programming at the lowest cost. It concludes that the concept of soft power can provide deep insight and better understanding on how to develop inexpensive visibility programme, yet capable of attracting a large number of people in a sustainable manner.


Author(s):  
Koen Stroeken ◽  
Cathy Abbo ◽  
Petra De Koker ◽  
Kristien Michielsen ◽  
Pieter Remes ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0121775 ◽  
Author(s):  
James R. Hargreaves ◽  
Calum Davey ◽  
Elizabeth Fearon ◽  
Bernadette Hensen ◽  
Shari Krishnaratne

Parasitology ◽  
2016 ◽  
Vol 144 (4) ◽  
pp. 450-458 ◽  
Author(s):  
F. ADDY ◽  
M. WASSERMANN ◽  
F. BANDA ◽  
H. MBAYA ◽  
J. ASCHENBORN ◽  
...  

SUMMARYThe zoonotic cestodeEchinococcus ortleppi(Lopez-Neyra and Soler Planas, 1943) is mainly transmitted between dogs and cattle. It occurs worldwide but is only found sporadically in most regions, with the notable exception of parts of southern Africa and South America. Its epidemiology is little understood and the extent of intraspecific variability is unknown. We have analysed in the present study the genetic diversity among 178E. ortleppiisolates from sub-Saharan Africa, Europe and South America using the complete mitochondrialcox1(1608 bp) andnad1(894 bp) DNA sequences. Genetic polymorphism within the loci revealed 15cox1and sixnad1haplotypes, respectively, and 20 haplotypes of the concatenated genes. Presence of most haplotypes was correlated to geographical regions, and only one haplotype had a wider spread in both eastern and southern Africa. Intraspecific microvariance was low in comparison withEchinococcus granulosussensu stricto, despite the wide geographic range of examined isolates. In addition, the various sub-populations showed only subtle deviation from neutrality and were mostly genetically differentiated. This is the first insight into the population genetics of the enigmatic cattle adaptedEchinococcus ortleppi. It, therefore, provides baseline data for biogeographical comparison amongE. ortleppiendemic regions and for tracing its translocation paths.


Sign in / Sign up

Export Citation Format

Share Document