scholarly journals Prevalence of metabolic syndrome in women with polycystic ovary syndrome attending an infertility clinic in a tertiary care hospital in south India

2012 ◽  
Vol 5 (1) ◽  
pp. 26 ◽  
Author(s):  
Korula George ◽  
Kavita Mandrelle ◽  
MohanS Kamath ◽  
DianJ Bondu ◽  
Achamma Chandy ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
South India ◽  
Tertiary Care Hospital ◽  
Polycystic Ovary ◽  
Tertiary Care ◽  
Care Hospital ◽  
Ovary Syndrome

scholarly journals Prevalence of metabolic syndrome in women with polycystic ovary syndrome attending a tertiary care hospital in West Delhi, India

2019 ◽  
Vol 8 (3) ◽  
pp. 1127
Author(s):  
Poonam Laul ◽  
Urvashi Miglani ◽  
Anish Laul ◽  
Pinkee Saxena ◽  
Megha Malhotra ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Tertiary Care ◽  
Multivariate Logistic Regression Analysis ◽  
Control Group ◽  
Care Hospital ◽  
Ovary Syndrome ◽  
High Prevalence ◽  
Healthy Control

Background: The aim of the present study was to evaluate the prevalence of metabolic syndrome in women with polycystic ovary syndrome (PCOS).Methods: All the women attending the gynae out-patient department of our hospital were screened for polycystic ovary syndrome as diagnosed by the Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group, 2004. Two hundred women with PCOS underwent screening for metabolic syndrome as defined by the national cholesterol education program adult treatment panel III (ATPIII) (2001) definition and the prevalence of metabolic syndrome was compared with two hundred age and BMI matched healthy control subjects. A multivariate logistic regression analysis was applied, and significant predictors identified for the prediction of metabolic syndrome.Results: The prevalence of metabolic syndrome among PCOS patients was 42 % in present study group as compared to 14 % in control group (p=0.01). The prevalence of metabolic syndrome was even higher in obese PCOS Vs non obese PCOS (52 % Vs 28.6 %). But even non-obese PCOS had higher prevalence of metabolic syndrome as compared to controls (28.6 % Vs 14 %).Conclusions: The study suggests a high prevalence of metabolic syndrome in patients with PCOS & thus it is important to screen all PCOS patients for manifestations of metabolic syndrome & its cardiovascular sequelae.

scholarly journals A study on the clinical, biochemical and hormonal profile of polycystic ovary syndrome patients attending tertiary care hospital

2017 ◽  
Vol 6 (5) ◽  
pp. 1986
Author(s):  
Spandana J. C. ◽  
Prasanna Kumar Shetty K. ◽  
Prasanna Kumar Shetty K.
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Genetic Disorder ◽  
Reproductive Age ◽  
Care Hospital ◽  
Observation Study ◽  
Ovary Syndrome ◽  
Hormonal Profile ◽  
Waist Hip Ratio

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder of reproductive age affecting 5% to 10% of women worldwide. It is a heterogenous, multifactorial, complex genetic disorder. PCOS receives a considerable attention because of its high prevalence and metabolic, reproductive and cardiovascular consequences.Methods: A cross sectional observation study of 100 PCOS patients was carried out between January 2014 to July 2015 in Gynaecology out-patient and Infertility OPD, Justice K. S. Hegde charitable hospital, Mangalore. The clinical, biochemical and hormonal profile of these patients were analysed and correlation was done between clinical features and biochemical and hormonal profile.Results: The prevalence of PCOS was 6.3% in the Gynaecology out-patient visits and 37.14% among infertile women. Menstrual irregularity was the most common complaint accounting for 31% followed by infertility (23%). Elevated leutinizing hormone and elevated LH: FSH was significant in irregular menstrual group. The prevalence of metabolic syndrome in our study was 21.3%. Spearmans correlation between various clinical and laboratory parameters showed menstrual cycle and body mass index(BMI) had a fair positive correlation and was significant. WHR (waist hip ratio) showed 21 times risk for metabolic syndrome.Conclusions: The study showed that most of our polycystic ovary syndrome subjects were hirsute, with central obesity and overweight or obese. Oligomenorrhea was the most common presentation. Among the various risk factors studied, WHR (waist hip ratio) showed 21 times risk for metabolic syndrome. Obese women with PCOS had more severe ovulatory dysfunction and need more attention for their appropriate management.

scholarly journals A study of metabolic syndrome in women with polycystic ovary syndrome at tertiary care center

2021 ◽  
Vol 10 (6) ◽  
pp. 2427
Author(s):  
Chelsae Kuntal ◽  
Jyotsna Vyas ◽  
Asha Chaudhary ◽  
Sunita Hemani ◽  
Lata Rajoria
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
Urban Areas ◽  
Polycystic Ovary ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Hormonal Profile ◽  
Increased Risk

Background: Polycystic ovary syndrome is a common endocrinopathy in women of reproductive age with prevalence of 6-10% which is characterized by hyper androgenic features and chronic oligo – anovulation and polycystic ovary morphology. Most women with polycystic ovary syndrome are also characterized by metabolic abnormalities like insulin resistance, hyperinsulinemia, dyslipidemia and abdominal obesity, these forming risk factors for metabolic syndrome. The objective of the study was to compare the clinical, biochemical and hormonal profile of polycystic ovary syndrome patients with and without metabolic syndrome.Methods: A comparative cross- sectional study was undertaken on 79 PCOS women diagnosed with PCOS according to Rotterdam criteria, in which the clinical data and hormonal profile of two groups of polycystic ovary syndrome women with and without metabolic syndrome was compared.Results: The mean age of 79 patients in this study group with and without metabolic syndrome was 26.17±3.18 and 25.57±3.41 years respectively. There were more patients from urban areas as compared to rural areas and maximum patients. Significantly higher number of PCOS women with metabolic syndrome had hirsutism and acanthosis nigricans than those without metabolic syndrome. Mean value of Waist circumference, systolic BP pressure, diastolic BP, S. Triglyceride and fasting glucose were higher and HDL levels were lower in women with metabolic syndrome than those without metabolic syndrome. Fasting insulin and HOMA-IR values were significantly higher in PCOS women with metabolic syndrome in comparison to those without metabolic syndrome.Conclusion: PCOS is not only is the most frequent cause of anovulation, but it is also associated with characteristic metabolic disturbances that may have important implications for the long term health. Metabolic syndrome is a cluster of endocrine disturbances, including insulin resistance, dyslipidemia, obesity, and hypertension. It is associated with a two-fold increased risk of cardiovascular disease and a five-fold increased risk of type 2 diabetes. This illustrates the importance of early detection of insulin resistance and metabolic syndrome with subsequent application of preventive measures in women with polycystic ovary syndrome.

scholarly journals PRESCRIPTION PATTERN IN OBESE AND NON-OBESE INFERTILE WOMEN WITH POLYCYSTIC OVARY SYNDROME IN A TERTIARY CARE HOSPITAL

2018 ◽  
Vol 11 (3) ◽  
pp. 53
Author(s):  
Asha Avirah Mm ◽  
Aswathy Alias ◽  
Manjusha Sajith ◽  
Vandana Nimbargi ◽  
Shivhar Kumdale
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Clomiphene Citrate ◽  
Treatment Options ◽  
Tertiary Care ◽  
Care Hospital ◽  
Lifestyle Modifications ◽  
Ovary Syndrome ◽  
Infertile Women ◽  
Current Medication

 Objective: The objective of this study is to evaluate the treatment options for the management of obese and non-obese infertile women with polycystic ovary syndrome (PCOS).Methods: A prospective observational study was conducted with 75 infertile PCOS women. The demographic details, body mass index, menstrual patterns, and current medication related to infertility were noted. The collected data were statistically represented in terms of range, frequency tables, and standard deviation wherever appropriate.Results: A majority of the infertile PCOS women were aged 24–27 years with a mean age of 25.72±3.53 years, belonging to middle socioeconomic class (44%) and mostly found to be urban residents 68%. Most of the PCOS women were overweight (32%) and obese (21%) with irregular menstrual pattern (90.67%). In combination therapy, clomiphene citrate (CC) pre-treated with oral contraceptives (OC) (37.93%) was mostly given to obese PCOS patients followed by CC with metformin pre-administered with OC (31.03%), whilen on-obese PCOS patients were mostly administered CC with gonadotropins pre-treated with OC(44%). In single therapy, OC was mostly administered to both non-obese (90%) and obese PCOS patients (88.90%).Conclusion: This study concluded that most of the infertile PCOS women were overweight and obese, a major risk actor causing hyperandrogenicity. CC pre-treated with OC and metformin with CC pre-treated with OC were mostly prescribed to obese PCOS patients. Lifestyle modifications along with treatment are strongly recommended, especially in obese PCOS patients.

scholarly journals Lipid Profile of Women with Polycystic Ovary Syndrome Attending a Tertiary Care Hospital of Dhaka City

2016 ◽  
Vol 8 (2) ◽  
pp. 47-49
Author(s):  
Rona Laila ◽  
Nusrat Mahmud ◽  
Monnujan Nargis ◽  
TA Chowdhury
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Lipid Profile ◽  
Polycystic Ovary ◽  
Tertiary Care ◽  
Care Hospital ◽  
Ovary Syndrome ◽  
Type2 Diabetes ◽  
Child Bearing ◽  
The Mean ◽  
Type2 Diabetes Mellitus

Polycystic ovary syndrome (PCOS) is one of the common disorders in women at child bearing age. The purpose of the present study was to investigate the lipid profile in patients with polycystic ovary syndrome. A total of 103 women with PCOS of 15-36 years of age were included in the present study. Of the 103 PCOS women, 50% were overweight or obese, 29.1% had impaired glucose tolerance (IGT) and 4.9% had type2 diabetes mellitus (T2DM). The mean BMI was generally higher (25.8±5.5 kg/m2). The mean serum cholesterol levels ranged from182 mg/dl to 236 mg/dl in all groups of women. The results of our study showed that women with PCOS had altered lipid profile and glycemic status. Therefore, evaluation of metabolic status is necessary for better management of women with PCOS.Ibrahim Med. Coll. J. 2014; 8(2): 47-49

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