Management of an intrastromal corneal epithelial cyst, from simple drainage to keratoplasty

In order to facilitate the corneal stromal ablation in photorefractive keratectomy the epithelium is removed so corneal repair associated with changes in epithelium and stroma. To study the corneal epithelial thickness and pachymetry profile changes after photorefractive keratectomy (PRK) for myopia. Retrospective analysis of the postoperative corneal epithelial thickness and pachymetry profile changes in 22 eyes of 12 patients treated with PRK for myopia or myopic astigmatism. Corneal and epithelial thickness maps within the central 6 mm were obtained by anterior segment spectral-domain optical coherence tomography (SD-OCT) preoperatively and at 3 months postoperatively. Correlations between pachymetry,epithelial thickness changes and the amount of correction,were analyzed.Compared to preoperative values,the central 2 mm and the paracentral 2 to 5 mm zone epithelium was 1 ± 2.85 and 1 ± 3.11 μm thicker,respectively,at 3 months postoperatively (P <.05). The spherical equivalent (SE) changed from-2.80 ± 2.028 diopters (D) preoperatively to -0.40 ± 0.42 D at 3 months postoperatively. Females show greater postoperative epithelial thickening, 2.6 ± 3.77 μm,than males,0.34 ± 1.98 μm. There was a trend toward greater epithelial thickening with a larger amount of programmed SE correction, and thinner preoperative epithelium. No correlation between epithelial thickness change and postoperative change in refraction was detected.Negative correlation between between age, refractive error,with the pre and post-operative pachymetry. In general female pachymetry reading is higher than it in male.The corneal epithelial thickness increased after PRK up to 3 months postoperatively. It was affected by the amount of myopia treated, gender, and preoperative epithelial thickness. The refractive outcomes did not affected by the postoperative epithelial thickening. Negative correlation between between age, refractive error, with the pre and post-operative pachymetry. In general female pachymetry reading is higher than it in male.

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Managing Corneal Epithelial Defects Using High Molecular Weight Fluorescein to Prevent Contact Lens Staining and Removal of Bandage Contact Lenses

Acta Scientific Ophthalmology ◽

10.31080/asop.2020.03.0145 ◽

2020 ◽

Vol 3 (8) ◽

pp. 20-22

Author(s):

Muhammad Hamza ◽

Chrishan Gunasekera ◽

Samar Nahas ◽

Z CX Lin ◽

Hatch Mukherjee ◽

...

Keyword(s):

Molecular Weight ◽

High Molecular Weight ◽

Contact Lens ◽

Contact Lenses ◽

Corneal Epithelial

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Intracardiac Epithelial Cyst Associated with Esophageal Atresia

Fetal and Pediatric Pathology ◽

10.3109/15513819709168758 ◽

1997 ◽

Vol 17 (6) ◽

pp. 945-949

Author(s):

Irene Scheimberg ◽

Simon Rose ◽

Marian Malone

Keyword(s):

Esophageal Atresia ◽

Epithelial Cyst

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Human medicines European public assessment report (EPAR): Holoclar, ex vivo expanded autologous human corneal epithelial cells containing stem cells, Stem Cell Transplantation,Corneal Diseases, Date of authorisation: 17/02/2015, Revision: 5, Status: Authorised

Case Medical Research ◽

10.31525/cmr-bb17af ◽

2019 ◽

Author(s):

Keyword(s):

Stem Cells ◽

Stem Cell ◽

Stem Cell Transplantation ◽

Ex Vivo ◽

Corneal Epithelial Cells ◽

Corneal Epithelial ◽

Assessment Report ◽

European Public ◽

European Public Assessment Report ◽

Human Corneal Epithelial Cells

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Comparison of Ocular Surface Cytological Appearance in Glaucoma Patient Treated with Timolol Maleat 0,5% Latanoprost 0,005% and Timolol-Latanoprost Fixed Combination Preservative Free Eye Drop

Ophthalmologica Indonesiana ◽

10.35749/journal.v44i2.167 ◽

2019 ◽

Vol 44 (2) ◽

pp. 82

Author(s):

Maretha Amrayni ◽

Elsa Gustianty ◽

Susi Heryati ◽

Andika Prahasta ◽

Maula Rifada ◽

...

Keyword(s):

Epithelial Cells ◽

Cell Density ◽

Goblet Cell ◽

Ocular Surface ◽

Fixed Combination ◽

Cell Contact ◽

Corneal Epithelial ◽

Preservative Free ◽

Goblet Cell Density ◽

Epithelial Metaplasia

Introduction : The longterm use of topical antiglaucoma might cause ocular surface instability due to active substance or preservative used. Impression cytology examination may reveal superficial epithelial cells on conjunctiva and cornea, including goblet cells. Goblet cell density decrease is the most important parameter on evaluation of ocular surface disorder. Objective : This study was to understand ocular surface remodeling due to active substance of topical antiglaucoma with impression cytology examination among the patient prior and 3 months after therapy. Methods : This was a randomized controlled trial study with single blind masking. A total of 45 eyes from 31 patients were used as subject and distributed onto three groups treatment, which were timolol maleat 0.5%, latanoprost 0.005%, and latanoprost-timolol maleat fixed combination. All topical antiglaucoma in this study were preservative free. Result : There were differences between 3 groups in goblet cells density after 3 months therapy (p=0,030). Goblet cell density in timolol group was lower than latanoprost (p=0,041) and fixed combination (p=0,045). There was no significantly difference between 3 groups in conjunctival epithelial metaplasia degree (p=0,706) and cell to cell contact degree in corneal epithelial cells (p=0.66) after 3 months therapy. Conjunctival epithelial metaplasia degree were increased among group of timolol (p=0,008) and fixed combination (p=0,046). Conclusion : Timolol maleat 0,5% caused lower goblet cell density after 3 months therapy compare with latanoprost and fixed combination. There was no significantly difference in conjunctival epithelial metaplasia and cell to cell contact degree in corneal epithelial cells among these glaucoma treatment groups.

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