scholarly journals Pattern of salivary gland tumors in Manipur, India: A 10 year study

2013 ◽  
Vol 02 (04) ◽  
pp. 250-253 ◽  
Author(s):  
Rajesh Singh Laishram ◽  
Arun Kumar K. ◽  
Gayatri Devi Pukhrambam ◽  
Sharmila Laishram ◽  
Kaushik Debnath
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Neoplastic Lesion ◽  
Chronic Sialadenitis ◽  
Significant Difference ◽  
North Eastern ◽  
Neoplastic Lesions ◽  
Malignant Group ◽  
Malignant Lesions

Abstract Background: Salivary gland lesions, especially the neoplastic lesions constitute a highly heterogeneous histopathologic group. Several studies have reported a significant difference in the global distribution of salivary gland tumors, but no formal study has been carried out in this part of the globe. Objectives: To document the pattern of various salivary gland tumors in Manipur, a state in North Eastern India. Materials and Methods: This is a 10 years (2002-2011) retrospective study of all salivary gland specimens received at our referral teaching hospital in Manipur, India. All the histopathology slides of salivary gland specimens during the study period were reviewed and clinical details were obtained from the archives. Restaining of slides and fresh sections of tissue blocks were performed whenever required. Data thus collected were analyzed. Results: A total of 104 cases of salivary gland lesions were studied during the study period. Age ranged from 5 years to 78 years with an overall slight female preponderance (M:F = 1:1.08). Parotid (56.65%) was the commonest gland involved followed by submandibular gland (31.73%). Neoplastic lesions comprised of 78 (75%) cases and non-neoplastic lesions constituted 25% (26 cases). Among the neoplastic lesions, benign lesions (53.85%) predominated over malignant lesions (21.15%). Pleomorphic adenoma was the commonest benign neoplastic lesion and mucoepidermoid carcinoma was the commonest malignant tumor. Chronic sialadenitis was the predominant lesion in the non-neoplastic group. Conclusion: The principal site for salivary gland tumors was the parotid gland and pleomorphic adenoma outnumbered all the other tumors. Females are more affected in the malignant group.

scholarly journals FNAC Spectrum of Salivary Gland Lesions in a Referral Pathology Lab - An Institutional Experience

2020 ◽  
Vol 7 (42) ◽  
pp. 2409-2413
Author(s):  
Bhavani C ◽  
Sravani P ◽  
Neeraja M ◽  
Shyam Prasad B.R.
Keyword(s):  
Salivary Gland ◽  
General Hospital ◽  
Pleomorphic Adenoma ◽  
Cost Effective ◽  
Major Salivary Gland ◽  
Government Medical College ◽  
Medical College ◽  
Presenting Symptoms ◽  
Chronic Sialadenitis ◽  
Neoplastic Lesions

BACKGROUND Salivary gland swellings are one of the common presenting symptoms in the outpatient department. These swellings are referred to the pathology department for determining the exact nature of the lesion to reach a diagnosis. Fine needle aspiration (FNA) of the salivary gland and diagnosis of the disease represents one of the most challenging areas in cytopathology. FNAC is widely used for preoperative diagnosis of many swellings and masses, including salivary gland lesions. It is a cost-effective, safe and straightforward procedure that provides valuable information for planning appropriate management. The present study aims to evaluate the efficacy and cytological spectrum of FNA of salivary gland lesions done over a fixed period in Government Medical College / Government General Hospital, Anantapuramu. METHODS This cross-sectional study was conducted in the Department of Pathology of Government Medical College / Government General Hospital, Anantapuramu, during the period January 2017 to December 2019. Patients with suspected salivary gland enlargements, who were referred for FNAC, were included in this study. FNAs of 80 patients were studied in the present study. FNAC was performed by using a 10 mL syringe with a 23 g needle. Smears were stained by using the H & E stain (Haematoxylin and Eosin). The data collected was entered into an Excel sheet and analysed. Chi-square and p-value were calculated using Open Epi software. RESULTS Cytology slides prepared were studied, interpreted, and the diagnosis made was analysed. Out of the 80 FNAC salivary gland lesions, 44 were non-neoplastic lesions, and 36 were neoplastic lesions. Of the non-neoplastic lesions, chronic sialadenitis was predominant (30), and among the neoplastic lesions, pleomorphic adenoma cases were dominant, accounting for 30 cases. In our study, the most common major salivary gland involved was the parotid gland. CONCLUSIONS FNAC of the salivary gland lesion is a simple, safe, rapid, cost-effective, convenient, harmless, well-tolerated procedure by patients, and it remains an accurate method for the diagnosis of salivary gland lesion for pathologists and physicians. Our study reflected a varied spectrum of lesions in patients referred for FNAC for the diagnosis of swellings of salivary glands. KEYWORDS FNAC, Cytology, Salivary Gland, Parotid, Pleomorphic Adenoma

scholarly journals Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma

2021 ◽  
Author(s):  
Costantino Ricci ◽  
Federico Chiarucci ◽  
Francesca Ambrosi ◽  
Tiziana Balbi ◽  
Barbara Corti ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Melanin Pigment ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Pertinent Literature

AbstractThe presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinical-pathological clues useful in the differential diagnosis with melanoma are discussed. In addition, a review of the pertinent literature is also proposed, discussing the pathologic mechanisms potentially involved in this phenomenon.

scholarly journals Epidemiologic Characteristics of Salivary Gland Tumors in an Iranian Population

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Nafise Shamloo ◽  
Alireza Ghanadan ◽  
Fahimeh Sadat Hashemian ◽  
Maedeh Ghorbanpour
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Malignant Tumors ◽  
The Body ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Cross Sectional ◽  
Adenoid Cystic

Background: Salivary gland tumors include a wide variety of benign and malignant tumors in the oral and maxillofacial region. Although these tumors are not common, they are not rare. The prevalence of these tumors varies with regard to age, gender, and their location in the body. Objectives: This study aimed to evaluate the frequency of benign and malignant salivary gland tumors in patients referred to three referral hospitals in Tehran, Iran. Methods: This retrospective cross-sectional study examined the demographic and pathologic records of the patients with salivary gland tumors submitted to the Department of Pathology of Amir Alam, Loghman Hakim, and Shohada Hospitals from 2005 to 2016. In this study, the histological variants of salivary gland tumors and clinical parameters such as age, gender, and the location of the tumor were examined. The clinical data were analyzed using SPSS software version 21. Results: Of 137632 patient records, 1180 cases were salivary gland tumors. Pleomorphic adenoma in 794 cases (67.3%) and adenoid cystic carcinoma in 109 cases (9.2%) were the most common tumors, respectively. Salivary gland tumors were more common in males, and the participants’ mean age was 42.86 ± 16.5 years. The most common site was parotid and minor salivary glands, with 937 (79.4%) and 137 (12%) cases, respectively. Conclusions: In this study, the most common benign tumor was pleomorphic adenoma in the parotid gland, and the most common malignant tumor was adenoid cystic carcinoma in the major salivary glands. Furthermore, benign tumors were more frequent than malignant tumors.

scholarly journals Primary Salivary Gland Tumors- A two years study at Nobel Medical College

2019 ◽  
Vol 2 (2) ◽  
pp. 234-238
Author(s):  
Niraj Nepal ◽  
Prabesh Kumar Choudhary ◽  
Manish Kumar Das ◽  
Meenakshi Basnet ◽  
Sagar Paudel
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Malignant Tumors ◽  
Age Groups ◽  
Salivary Gland Tumor ◽  
Salivary Gland Tumors ◽  
Parotid Glands ◽  
Gland Tumor ◽  
Medical College

Introduction: Salivary gland tumors are a heterogeneous group of neoplasms that are relatively rare but represent a wide variety of both benign and malignant histopathologic subtypes. The aim of this study was to find out the histopathological distribution of primary salivary gland tumors and correlate fine needle aspiration cytology reports with histological findings.Materials and Methods: A total of 83 patients attending the otorhinolaryngology department with salivary gland tumors were enrolled in our study. The histopathological findings were reported and correlated with cytological findings.Results: The mean age of the patient with salivary tumors was 43.11 ± 13.02 years. Out of 83 cases, 3 (3.6%) patients were diagnosed as inflammatory lesions, 64 (77.1%) patients had benign salivary gland tumors and 16 (19.3%) of patients had malignant salivary glands tumors in histopathology. The sensitivity and specificity of FNAC in this series for detecting salivary gland malignancy were 68.8% and 98.5% respectively with an overall diagnostic accuracy of 92.8%. The most common salivary gland tumor was found to be pleomorphic adenoma (56.6%) and the most common malignant salivary gland tumor was found to be mucoepidermoid carcinoma (19.3%). The comparison of the incidence of salivary gland tumors in various age groups showed a statisticallysignificant difference (p=0.009).  Conclusions: Benign salivary tumors are more common than malignant tumors with the most common occurrence in parotid glands. Pleomorphic adenoma is the most common benign tumor whereas; mucoepidermoid carcinoma is the most common malignant tumor in patients visiting Nobel medical college.

scholarly journals Pleomorphic Adenoma of Minor Salivary Gland in Buccal Mucosa: an Uncommon Finding

2015 ◽  
Vol 03 (01) ◽  
pp. 047-050
Author(s):  
Gourav Ahuja ◽  
Jaideep Marya ◽  
Poonam Sood
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Buccal Mucosa ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Minor Salivary Glands ◽  
Diverse Range ◽  
Neck Tumors

AbstractSalivary gland tumors account for less than 3% of the head and neck tumors. Among various salivary gland tumors, pleomorphic adenoma is most common and accounts for 60- 70% of the benign tumors of salivary glands. However, the involvement of minor salivary glands of buccal mucosa is extremely uncommon and reported to be 4% only. Salivary glands may present with a diverse range of lesions presenting a challenge to even the most experienced clinician. We report two rare cases of pleomorphic adenoma of minor salivary glands of buccal mucosa in a 45 year old female and 70 years old male respectively. It includes clinical features, diagnosis and treatment of the tumor.

scholarly journals Oncocytoma: a mystifying parotid mass

2019 ◽  
Vol 6 (4) ◽  
pp. 1418
Author(s):  
Jeevan G. Sanjive ◽  
N. S. Reddy ◽  
V. Soundara Rajan
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Residual Disease ◽  
Histopathological Examination ◽  
Ct Imaging ◽  
Salivary Gland Tumors ◽  
Age Group ◽  
Elderly Age ◽  
Parotid Swelling

Parotid oncocytoma presents in less than 1% of salivary gland tumors. Therefore, there are only very few reported cases in literature. This tumor is often diagnosed in elderly age group. It is often misdiagnosed clinically as pleomorphic adenoma, hemangioma or Warthin’s tumor. CT imaging usually shows an enhancing lobulated mass; however, it cannot exactly diagnose oncocytoma. It can be confirmed only by histopathological examination. This case report is of an Indian female of 66 years with parotid swelling who underwent total conservative parotidectomy. Post operatively, patient has no residual disease and complications.

scholarly journals A Juvenile Pleomorphic adenoma of the palate

2021 ◽  
Author(s):  
Bouthaina Hammami ◽  
Mohamed Amine Chaabouni ◽  
Ghada Yousfi ◽  
Omar Walha ◽  
Malek Mnejja ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Radiological Features

Salivary gland tumors in children are rare, involvement of accessory salivary glands is exceptional. We report a case of pleomorphic adenoma of the palate in a child in order to describe the clinical, radiological features, as well as the management of this rare localization.

scholarly journals FNAC and histopathological correlation of salivary gland lesions: an observational study

2017 ◽  
Vol 4 (7) ◽  
pp. 2148 ◽  
Author(s):  
Sneha Kakoty ◽  
Tridip Dutta Baruah ◽  
C. P. Ganesh Babu
Keyword(s):  
Salivary Gland ◽  
Observational Study ◽  
Needle Aspiration ◽  
Age Group ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

Background: Fine needle aspiration cytology (FNAC) is a sensitive and specific and yet an economically effective technique for diagnosis of salivary gland lesions. FNAC of salivary glands has achieved a pivotal role in the diagnosis and management of salivary gland lesions since its induction by Stewart et al in 1933. However, it has always been under scrutiny when compared to histopathology. Histopathology of salivary gland lesions is still the final method to establish diagnosis and predicting prognosis in these lesions.1Methods: A prospective observational study of 50 patients with salivary gland lesions was done at Gauhati Medical College and hospital from June 2011 to May 2012. 39 patients underwent histopathological confirmation. Cases with histopathological correlation were included in calculating diagnostic accuracy. The cytological findings were correlated with that of the histopathological diagnosis to obtain the accuracy of the cytological diagnosis. The parameters of diagnostic validity of the cytological technique in terms of sensitivity, specificity and predictive value were evaluated.Results: Study population included patients of age group ranging from 13-70 years with median age group being 31-40 years (30%). 54% of the affected patients were male with the parotid being the most commonly involved gland (62%). Neoplastic lesions constituted the major bulk of the lesions (39 cases, 78%) with benign tumours constituting 54%. The most commonly involved benign neoplastic lesion was pleomorphic adenoma (22cases, 44%). Among the non-neoplastic lesions (22%), the acute sialadenitis was frequently noted. Histopathological correlations were available in 39 cases with 11 cases being the malignant lesions. The acute sialadenitis lesions did not undergo histological examination. 28 cases of non-malignant lesions underwent the histological confirmation. In the present study, the specificity and the sensitivity were found to be 96.42% and 90.91% respectively. The predictive value of salivary gland cytology was 90.91% and diagnostic accuracy was 94.87%.Conclusions: Fine Needle Aspiration Cytology is thus a safe, reliable, quick, convenient and accurate method of diagnosis and should be considered as one of the first line of investigations in the evaluation of salivary gland lesions.

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