scholarly journals Pleomorphic Adenoma of Minor Salivary Gland in Buccal Mucosa: an Uncommon Finding

2015 ◽  
Vol 03 (01) ◽  
pp. 047-050
Author(s):  
Gourav Ahuja ◽  
Jaideep Marya ◽  
Poonam Sood
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Buccal Mucosa ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Minor Salivary Glands ◽  
Diverse Range ◽  
Neck Tumors

AbstractSalivary gland tumors account for less than 3% of the head and neck tumors. Among various salivary gland tumors, pleomorphic adenoma is most common and accounts for 60- 70% of the benign tumors of salivary glands. However, the involvement of minor salivary glands of buccal mucosa is extremely uncommon and reported to be 4% only. Salivary glands may present with a diverse range of lesions presenting a challenge to even the most experienced clinician. We report two rare cases of pleomorphic adenoma of minor salivary glands of buccal mucosa in a 45 year old female and 70 years old male respectively. It includes clinical features, diagnosis and treatment of the tumor.

scholarly journals Epidemiologic Characteristics of Salivary Gland Tumors in an Iranian Population

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Nafise Shamloo ◽  
Alireza Ghanadan ◽  
Fahimeh Sadat Hashemian ◽  
Maedeh Ghorbanpour
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Malignant Tumors ◽  
The Body ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Cross Sectional ◽  
Adenoid Cystic

Background: Salivary gland tumors include a wide variety of benign and malignant tumors in the oral and maxillofacial region. Although these tumors are not common, they are not rare. The prevalence of these tumors varies with regard to age, gender, and their location in the body. Objectives: This study aimed to evaluate the frequency of benign and malignant salivary gland tumors in patients referred to three referral hospitals in Tehran, Iran. Methods: This retrospective cross-sectional study examined the demographic and pathologic records of the patients with salivary gland tumors submitted to the Department of Pathology of Amir Alam, Loghman Hakim, and Shohada Hospitals from 2005 to 2016. In this study, the histological variants of salivary gland tumors and clinical parameters such as age, gender, and the location of the tumor were examined. The clinical data were analyzed using SPSS software version 21. Results: Of 137632 patient records, 1180 cases were salivary gland tumors. Pleomorphic adenoma in 794 cases (67.3%) and adenoid cystic carcinoma in 109 cases (9.2%) were the most common tumors, respectively. Salivary gland tumors were more common in males, and the participants’ mean age was 42.86 ± 16.5 years. The most common site was parotid and minor salivary glands, with 937 (79.4%) and 137 (12%) cases, respectively. Conclusions: In this study, the most common benign tumor was pleomorphic adenoma in the parotid gland, and the most common malignant tumor was adenoid cystic carcinoma in the major salivary glands. Furthermore, benign tumors were more frequent than malignant tumors.

scholarly journals An unusual pleomorphic adenoma

2014 ◽  
Vol 62 (3) ◽  
pp. 319-324
Author(s):  
Christiano Sampaio QUEIROZ ◽  
Roberto Almeida de AZEVEDO ◽  
Antonio Irineu TRINDADE NETO ◽  
Caetano Guilherme Carvalho PONTES ◽  
Rafael de Queiroz MOURA
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Histopathological Examination ◽  
Minor Salivary Gland ◽  
Surgical Excision ◽  
Biological Behavior ◽  
Surgical Removal ◽  
Minor Salivary Glands ◽  
Recommended Treatment

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.

scholarly journals Nasopharyngeal Pleomorphic Adenoma: A Rare Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Serdal Celik ◽  
Osman Kilic ◽  
Tulay Zenginkinet ◽  
M. Tayyar Kalcioglu
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Relevant Literature ◽  
Minor Salivary Gland ◽  
Minor Salivary Glands ◽  
Review Of The Literature ◽  
Neck Tumors ◽  
Rare Case Report ◽  
Chondroid Metaplasia

Salivary gland tumors are rare among all head and neck tumors. Pleomorphic adenoma (PA) is the most commonly seen subtype, and 85% of the cases are located in the parotid gland. PA may very rarely be seen in minor salivary glands. Minor salivary gland PAs are mostly located in the hard and soft palates. Nasopharyngeal PA is very rare, and a total of 8 cases have been published to date. In this case report, a 51-year-old female patient who had nasopharyngeal PA with chondroid metaplasia is presented, and we review the relevant literature.

Salivary Gland Tumors in Libyan Population: A 20- Years Retrospective Study

2021 ◽  
pp. 43-52
Author(s):  
Mansora Hamad ◽  
Salwa Ahmeida ◽  
Samar Hamed ◽  
Jamila Issawi
Keyword(s):  
Salivary Gland ◽  
Retrospective Study ◽  
Pleomorphic Adenoma ◽  
Minor Salivary Gland ◽  
Pathological Finding ◽  
Salivary Gland Tumors ◽  
Radiology Department ◽  
Benign Tumors ◽  
Anatomical Location ◽  
Histopathological Diagnosis

Background and objectives. Salivary gland tumors (SGT) are relatively uncommon. It pose considerable challenging in diagnosis because their histopathological features and behavior diversity. There are several epidemiological studies describe their incidence and frequency. The current study aims to investigate the diverse histological types and distribution clinical characters. Methods. A retrospective study was carried out in oral diagnosis, oral medicine, oral pathology and radiology department of faculty of dentistry at Benghazi university from 2000 to 2019. Information gathered contained the year of diagnosis, age, gender, site, symptoms and histopathological diagnosis. The data collected was analyzed with SPSS. Result. Of the total 60 salivary gland tumors, 25 (41.7%) was benign tumors in which the pleomorphic adenoma was the most common type (n=24, 96%), and malignant tumors account (n=35, 38.3%) with mucoepidermoid carcinoma is the most frequent (n=41, 40%). Female to male ratio was 1.3:1 with average age of 40.5 (range 11-94). About 91.1% of salivary gland tumors were diagnosed in minor salivary gland where most of cases occurred in palate by 8.9%. Major salivary glands were affected by 8.9% mostly in parotid gland (7.2%). Most of cases were diagnosed as painless swelling. Conclusion: Malignant salivary gland tumors more common the benign type with the palate is the principle anatomical location. Pleomorphic adenoma was the most common pathological finding with predominance of female over male.

scholarly journals Exérese cirúrgica de adenoma pleomórfico em palato: relato de caso

2020 ◽  
Vol 9 (5) ◽  
pp. 449-452
Author(s):  
Laís Guimarães Pinto ◽  
Nathalia Farias Dantas de Figueiredo ◽  
Thaynara Cavalcante Moreira Romão ◽  
Lucas André Barros Ferreira ◽  
Murilo Quintão dos Santos ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Hard Palate ◽  
Minor Salivary Gland ◽  
Minor Salivary Glands ◽  
Mucin 1 ◽  
Histologic Study ◽  
Clin Pathol ◽  
Minor Salivary Gland Tumors

Introdução: O adenoma pleomórfico (AP) é um tumor de glândulas salivares, misto, benigno composto de células epiteliais e mioepiteliais dispostas em vários padrões morfológicos, demarcadas dos tecidos circundantes por uma cápsula fibrosa. Dentre as glândulas salivares, é predominante nas intraorais com maior frequência no palato. Sua etiopatologia ainda é controversa. Objetivo: Relatar um caso clínico de adenoma pleomórfico localizado em região póstero lateral direito, do palato tratado cirurgicamente. Relato do Caso: Paciente, sexo feminino, 55 anos, foi encaminhada com laudo histopatológico de adenoma pleomórfico. Ao exame físico, foi observou um aumento de volume caracterizado como um nódulo séssil, consistente à palpação, localizado em palato duro direito, com aproximadamente 4cm de extensão em seu maior diâmetro, superfície íntegra, coloração normal e indolor. Ao exame tomográfico, imagem unilocular, bem delimitada, com reabsorção óssea local. Como tratamento, optou-se pela exérese cirúrgica da lesão sob anestesia geral, a qual foi realizada sem intercorrências. Paciente atualmente se encontra com 1 ano de pós-operatório sem sinais de recidiva. Conclusão: O tipo de tratamento descrito apresenta excelente prognóstico, com baixas taxas de recidiva.Descritores: Adenoma Pleomorfo; Cirurgia Bucal; Patologia Bucal.ReferênciasSharma A, Deshmukh S, Shaikh A, Dabholkar J. Pleomorphic adenoma of the minor salivary gland of the cheek. Singapore Med J. 2013;54(9):e183-4. Arumugam P, Christopher PJ, Kumar S, Kengasubbiah S, Shenoy V. Pleomorphic adenoma of the palate: a. case report. Cureus 11(3):e4308.Khan MN, Raza SS, Hussain Zaidi SA, Haq IU, Hussain AK, Nadeem MD, Farid K. Pleomorphic Adenoma Of Minor Salivary Glands. J Ayub Med Coll Abbottabad. 2016;28(3):620-22. Chaturvedi M, Jaidev A, Thaddanee R, Khilnani AK. Large Pleomorphic Adenoma of Hard Palate. Ann Maxillofac Surg. 2018;8(1):124-126.Oliveira LJ, Castro HHO, Leão PLR, Leal RM, Horta MCR, Souza PEA. Tratamento de adenoma pleomórfico em palato: relato de 2 casos e revisão de literatura. Rev Port Estomatol Med Dent Cir Maxilofac. 2016;57(1):55-61.Porto DE, Cavalcante JR, Cavalcante Júnior JR, Costa MCF, Pereira SM. Adenoma Pleomórfico de Parótida – Relato de Caso. Rev cir traumatol buco-maxilo-fac. 2014;14(2):15-18;Melo MNB, Nogueira Neto JN, Souza SR, Dultra FKAA, Dultra JA. Adenoma pleomórfico em lábio superior: Relato de caso. Rev. cir. traumatol. buco-maxilo-fac.2016;16(2):40-3.Erdem MA, Cankaya AB, Güven G, Olgaç V, Kasapoğlu C. Pleomorphic adenoma of the palate. J Craniofac Surg. 2011;22(3):1131-4.Takahashi H, Fujita S, Tsuda N, Tezuka F, Okabe H. Intraoral minor salivary gland tumors: a demographic and histologic study of 200 cases. Tohoku J Exp Med. 1990;161(2):111-28. Loiola RF, Matos FR, Nonaka CFW, Lopes FF, Cruz MCFN. Perfil epidemiológico das neoplasias de glândulas salivares diagnosticadas em São Luís-MA. J Bras Patol Med Lab. 2009;45(5):413-20.Tiago RSL, Castro GA, Ricardo LAC, Bühler RB, Fava AS. Adenoma pleomórfico de parótida: aspectos clínicos, diagnósticos e terapêuticos. Rev Bras Otorrinolaringol. 2003;69(4):485-89.Khan MN, Raza SS, Hussain Zaidi SA, Haq IU, Hussain AK, Nadeem MD, Farid K. Pleomorphic Adenoma Of Minor Salivary Glands. J Ayub Med Coll Abbottabad. 2016;28(3):620-22. Soares AB, Demasi APD, Altemani A, Araújo VC. Increased mucin 1 expression in recurrence and malignant transformation of salivary gland pleomorphic adenoma. Histopathology. 2011; 58(3):377-82.Soares AB, Demasi AP, Tincani AJ, Martins AS, Altemani A, de Araújo VC. The increased PDGF-A, PDGF-B and FGF-2 expression in recurrence of salivary gland pleomorphic adenoma. J Clin Pathol. 2012;65(3):272-77.Maia FPA, Oliveira PRK, Santos JVQM, Costa DFN, Andrade ESS. Abordagem minimamente invasiva para tratamento de adenoma pleomórfico em palato: caso clínico. Rev Cir Traumatol Bucomaxilofac. 2019;19(3):21-4.

Pleomorphic Adenoma of Buccal Mucosa: A Rare Clinical Entity

2020 ◽  
Author(s):  
Sooraj Somah
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Buccal Mucosa ◽  
Histopathological Examination ◽  
Imaging Techniques ◽  
Salivary Gland Tumor ◽  
Neck Region ◽  
Surgical Excision ◽  
Minor Salivary Glands

Salivary gland tumors are rare tumors in the head and neck region and Pleomorphic Adenoma (PA) is the commonest salivary gland tumor. It is a benign tumor usually affecting parotid, submandibular or minor salivary glands. In minor salivary glands, the palate and lip are the commonest sites. Histopathological examination and various imaging techniques aid n diagnosis. Wide surgical excision is the treatment of choice. Here we present a rare case of PA of the buccal mucosa.

scholarly journals Secretory Carcinoma of Minor Salivary Gland in Buccal Mucosa: A Case Report and Review of the Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Durga Paudel ◽  
Michiko Nishimura ◽  
Bhoj Raj Adhikari ◽  
Daichi Hiraki ◽  
Aya Onishi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Buccal Mucosa ◽  
Benign Lesion ◽  
Minor Salivary Gland ◽  
World Health ◽  
Positive Staining ◽  
Minor Salivary Glands ◽  
Secretory Carcinoma ◽  
Eosinophilic Cytoplasm

Secretory carcinoma (SC) of the salivary gland was recently added to the fourth edition of the World Health Organization classification of head and neck tumors. Some salivary tumors, including acinic cell carcinoma, have been reclassified as SC. Most of these tumors are located on the parotid gland with very few cases reported in the minor salivary glands of the buccal mucosa. Herein, we present a case of SC of buccal mucosa, which appeared clinically as a benign lesion in a 54-year-old Japanese female patient. Histopathologically, the tumor cells presented with an eosinophilic cytoplasm with microcytic structure along with eosinophilic secretory material and hemosiderin deposit. Immunohistochemical staining revealed strongly positive staining for S100, vimentin, and mammaglobin and negative staining for DOG-1. The tumor was finally diagnosed as secretory carcinoma of the buccal mucosa. We present a review of the medical literature of SC arising from minor salivary glands. We found only 15 cases of SC of buccal mucosa out of 63 cases of SC in the minor salivary glands. They showed good prognoses and only one case of SC in the buccal mucosa exhibited local recurrence and lymph node metastases.

scholarly journals Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases

2002 ◽  
Vol 57 (6) ◽  
pp. 271-276 ◽  
Author(s):  
Pablo Agustin Vargas ◽  
Renê Gerhard ◽  
Vergílius J. F. Araújo Filho ◽  
Inês Vieira de Castro
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Malignant Tumors ◽  
Epidemiological Studies ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Minor Salivary Glands ◽  
Adenoid Cystic ◽  
Malignant Salivary Gland Tumors

Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant salivary gland tumors in Brazil. MATERIAL AND METHODS: Hospital records of 124 patients with salivary gland tumors diagnosed from January 1993 to December 1999 were reviewed. The patients were analyzed according to gender, age, size, location, and histopathology of the tumor. RESULTS AND CONCLUSIONS: Patients with benign and malignant tumors presented with a mean age of 47.7 and 48.8 years, respectively. The frequency of benign tumors was 80% (n = 99) and malignant tumors 20% (n = 25). Tumors were localized in the parotid gland 71% (n = 88), in the submandibular gland 24% (n = 30), and in the minor salivary glands 5% (n = 6). The most common benign tumors were pleomorphic adenoma in 84% (n = 84) and Warthin's tumor in 13% (n = 13). Among malignant tumors, mucoepidermoid carcinoma was the most common in 52% (n = 13), adenoid cystic carcinoma occurred in 20% (n = 5), and carcinoma ex pleomorphic adenoma was detected in 12% (n = 3).

Terminal duct adenocarcinomas of the parotid gland

1995 ◽  
Vol 109 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Bonnie L. Kemp ◽  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Sophia N. Kotliar ◽  
Mario A. Luna
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Minor Salivary Gland ◽  
Low Grade ◽  
Minor Salivary Glands ◽  
Biological Behaviour ◽  
Parotid Neoplasms ◽  
Clinicopathological Study

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.

scholarly journals Pleomorphic Adenoma of the Cervical Heterotopic Salivary Gland: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Saman Vegari ◽  
Masoud Naderpour ◽  
Alireza Hemmati ◽  
Hosein Baybordi
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Complete Resection ◽  
Cervical Region ◽  
Minor Salivary Glands ◽  
Pathologic Evaluation ◽  
Painless Mass

Introduction. Although pleomorphic adenoma is the most common neoplasm of the salivary glands, this tumor most commonly involves the minor salivary glands of palatal and rarely occurs in cervical region.Case Report. A 21-year-old female referred to our clinic due to painless mass of right upper region of neck. After paraclinical and pathologic evaluation, it was diagnosed as cervical pleomorphic adenoma.Conclusion. Pleomorphic adenoma may be rarely involving the neck. Although the prognosis is good, the choice treatment is the complete resection of the tumor.

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