scholarly journals FNAC Spectrum of Salivary Gland Lesions in a Referral Pathology Lab - An Institutional Experience

2020 ◽  
Vol 7 (42) ◽  
pp. 2409-2413
Author(s):  
Bhavani C ◽  
Sravani P ◽  
Neeraja M ◽  
Shyam Prasad B.R.
Keyword(s):  
Salivary Gland ◽  
General Hospital ◽  
Pleomorphic Adenoma ◽  
Cost Effective ◽  
Major Salivary Gland ◽  
Government Medical College ◽  
Medical College ◽  
Presenting Symptoms ◽  
Chronic Sialadenitis ◽  
Neoplastic Lesions

BACKGROUND Salivary gland swellings are one of the common presenting symptoms in the outpatient department. These swellings are referred to the pathology department for determining the exact nature of the lesion to reach a diagnosis. Fine needle aspiration (FNA) of the salivary gland and diagnosis of the disease represents one of the most challenging areas in cytopathology. FNAC is widely used for preoperative diagnosis of many swellings and masses, including salivary gland lesions. It is a cost-effective, safe and straightforward procedure that provides valuable information for planning appropriate management. The present study aims to evaluate the efficacy and cytological spectrum of FNA of salivary gland lesions done over a fixed period in Government Medical College / Government General Hospital, Anantapuramu. METHODS This cross-sectional study was conducted in the Department of Pathology of Government Medical College / Government General Hospital, Anantapuramu, during the period January 2017 to December 2019. Patients with suspected salivary gland enlargements, who were referred for FNAC, were included in this study. FNAs of 80 patients were studied in the present study. FNAC was performed by using a 10 mL syringe with a 23 g needle. Smears were stained by using the H & E stain (Haematoxylin and Eosin). The data collected was entered into an Excel sheet and analysed. Chi-square and p-value were calculated using Open Epi software. RESULTS Cytology slides prepared were studied, interpreted, and the diagnosis made was analysed. Out of the 80 FNAC salivary gland lesions, 44 were non-neoplastic lesions, and 36 were neoplastic lesions. Of the non-neoplastic lesions, chronic sialadenitis was predominant (30), and among the neoplastic lesions, pleomorphic adenoma cases were dominant, accounting for 30 cases. In our study, the most common major salivary gland involved was the parotid gland. CONCLUSIONS FNAC of the salivary gland lesion is a simple, safe, rapid, cost-effective, convenient, harmless, well-tolerated procedure by patients, and it remains an accurate method for the diagnosis of salivary gland lesion for pathologists and physicians. Our study reflected a varied spectrum of lesions in patients referred for FNAC for the diagnosis of swellings of salivary glands. KEYWORDS FNAC, Cytology, Salivary Gland, Parotid, Pleomorphic Adenoma

scholarly journals Pattern of salivary gland tumors in Manipur, India: A 10 year study

2013 ◽  
Vol 02 (04) ◽  
pp. 250-253 ◽  
Author(s):  
Rajesh Singh Laishram ◽  
Arun Kumar K. ◽  
Gayatri Devi Pukhrambam ◽  
Sharmila Laishram ◽  
Kaushik Debnath
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Neoplastic Lesion ◽  
Chronic Sialadenitis ◽  
Significant Difference ◽  
North Eastern ◽  
Neoplastic Lesions ◽  
Malignant Group ◽  
Malignant Lesions

Abstract Background: Salivary gland lesions, especially the neoplastic lesions constitute a highly heterogeneous histopathologic group. Several studies have reported a significant difference in the global distribution of salivary gland tumors, but no formal study has been carried out in this part of the globe. Objectives: To document the pattern of various salivary gland tumors in Manipur, a state in North Eastern India. Materials and Methods: This is a 10 years (2002-2011) retrospective study of all salivary gland specimens received at our referral teaching hospital in Manipur, India. All the histopathology slides of salivary gland specimens during the study period were reviewed and clinical details were obtained from the archives. Restaining of slides and fresh sections of tissue blocks were performed whenever required. Data thus collected were analyzed. Results: A total of 104 cases of salivary gland lesions were studied during the study period. Age ranged from 5 years to 78 years with an overall slight female preponderance (M:F = 1:1.08). Parotid (56.65%) was the commonest gland involved followed by submandibular gland (31.73%). Neoplastic lesions comprised of 78 (75%) cases and non-neoplastic lesions constituted 25% (26 cases). Among the neoplastic lesions, benign lesions (53.85%) predominated over malignant lesions (21.15%). Pleomorphic adenoma was the commonest benign neoplastic lesion and mucoepidermoid carcinoma was the commonest malignant tumor. Chronic sialadenitis was the predominant lesion in the non-neoplastic group. Conclusion: The principal site for salivary gland tumors was the parotid gland and pleomorphic adenoma outnumbered all the other tumors. Females are more affected in the malignant group.

scholarly journals PLEOMORPHIC ADENOMA IN AN UNUSUAL SITE

2020 ◽  
pp. 66-67
Author(s):  
Ruban Kumar J ◽  
Shobana M ◽  
Dinesh K B ◽  
Shruthi kamal V
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Major Salivary Gland ◽  
Minor Salivary Glands ◽  
Upper Lip ◽  
Unusual Site ◽  
Medical College ◽  
Parotid Tumour

Pleomorphic adenoma is also called as mixed parotid tumour, which is a benign neoplasm of the salivary gland, occurring more frequently in major salivary gland. It occurs infrequently in minor salivary glands. It can involve the palate and lips as well. The aim of this paper is to report the case of a 24 year old male, admitted in Saveetha medical college and hospital, with complaints of swelling in the upper lip for 6 months, which was successfully diagnosed as pleomorphic adenoma and treated with surgical excision.

scholarly journals Salivary gland tumours - a three years experience at King Edward Medical College, Lahore

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Asmaa Qureshi ◽  
Khalilur Rehman ◽  
Sohail Husain ◽  
Nasirul Hasan Khawaja ◽  
Ghulam Rasood Qureshi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Single Case ◽  
Malignant Neoplasms ◽  
Salivary Gland Tumours ◽  
Medical College ◽  
Common Location ◽  
Female Predominance

Salivary gland tumours make an important part of oral & maxillofacial pathology. Only few studies have been done in Pakistani population. The aim of this study was to describe morphological types of salivary gland tumours diagnosed at King Edward Medical College/ Mayo Hospital, Lahore during the years 1999-2001 and to compare their demographic data with those previously published. Material & Methods: This descriptive cross-sectional study was carried out at King Edward Medical College/ Mayo Hospital, Lahore. It reports 117 cases of salivary gland tumours diagnosed at Pathology Department during 1999-2001. Results: Of the 128 specimens of salivary glands, 117(91.4%) were confirmed as salivary neoplasms. Out of them, 62.7% were benign and 37.6% malignant and a slight female predominance (58.1%) was found. The most common location was the parotid gland (65.8%) followed by minor salivary glands (19.6%). Majority oft he t tumours was diagnosed during 3rd to 5 decades of life. Median age for benign tumours was 33 years (range 1-78) and a female predominance (58.9%) was seen again. Median age for malignant neoplasms was 45 years (range 9-70) with a female predilection ( 56.8%). However, 4 out o f 5 patients with Warthin`s tumour were men. Pleomorphic adenoma was the most frequent tumour (51.3%), followed by mucoepidermoid carcinoma (25.6%), adenoid cystic carcinoma (7.7)), Warthin`s tumour (4.3%) and monomorphic adenoma (2.6%). Two cases each of oncytoma & adenocarcinoma were recorded. Rare categories (single case each) of salivary tumours included lipoma, acinic cell carcinoma, basal cell adenoma, capillary haemangioma, metastatic carcinoma and non Hodgkin`s lymphoma. Conclusion: The principal site of salivary tumours was the parotid gland and females were most affected. Pleomorphic adenoma was the most frequent finding. The results of this study are comparable with other studies.

scholarly journals Primary Salivary Gland Tumors- A two years study at Nobel Medical College

2019 ◽  
Vol 2 (2) ◽  
pp. 234-238
Author(s):  
Niraj Nepal ◽  
Prabesh Kumar Choudhary ◽  
Manish Kumar Das ◽  
Meenakshi Basnet ◽  
Sagar Paudel
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Malignant Tumors ◽  
Age Groups ◽  
Salivary Gland Tumor ◽  
Salivary Gland Tumors ◽  
Parotid Glands ◽  
Gland Tumor ◽  
Medical College

Introduction: Salivary gland tumors are a heterogeneous group of neoplasms that are relatively rare but represent a wide variety of both benign and malignant histopathologic subtypes. The aim of this study was to find out the histopathological distribution of primary salivary gland tumors and correlate fine needle aspiration cytology reports with histological findings.Materials and Methods: A total of 83 patients attending the otorhinolaryngology department with salivary gland tumors were enrolled in our study. The histopathological findings were reported and correlated with cytological findings.Results: The mean age of the patient with salivary tumors was 43.11 ± 13.02 years. Out of 83 cases, 3 (3.6%) patients were diagnosed as inflammatory lesions, 64 (77.1%) patients had benign salivary gland tumors and 16 (19.3%) of patients had malignant salivary glands tumors in histopathology. The sensitivity and specificity of FNAC in this series for detecting salivary gland malignancy were 68.8% and 98.5% respectively with an overall diagnostic accuracy of 92.8%. The most common salivary gland tumor was found to be pleomorphic adenoma (56.6%) and the most common malignant salivary gland tumor was found to be mucoepidermoid carcinoma (19.3%). The comparison of the incidence of salivary gland tumors in various age groups showed a statisticallysignificant difference (p=0.009).  Conclusions: Benign salivary tumors are more common than malignant tumors with the most common occurrence in parotid glands. Pleomorphic adenoma is the most common benign tumor whereas; mucoepidermoid carcinoma is the most common malignant tumor in patients visiting Nobel medical college.

scholarly journals Etiology and familial inheritance of pleomorphic adenomas

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Krysten Clark
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
White Male ◽  
Salivary Gland Tumor ◽  
Major Salivary Gland ◽  
Gland Tumor ◽  
Superficial Lobe ◽  
Increased Risk ◽  
Pleomorphic Adenomas

Background: A pleomorphic adenoma is the most common salivary gland neoplasm in both children and adults. Pleomorphic adenomas are derived from ductal and myoepithelial cells and are most commonly found in the superficial lobe of the parotid gland. The purpose of this article is to discuss the genes involved in pleomorphic adenomas and the possible autosomal dominant mode of inheritance. Case Description: The first patient was a white male who was diagnosed with carcinoma ex pleomorphic adenoma, a highly aggressive tumor, at the age of 57. He had an undiagnosed pleomorphic adenoma for approximately 15 years prior. The tumor was excised and the patient underwent radiation in the location of his parotid gland for 4 years until he deceased. The second patient is a white female, his daughter, who was diagnosed with a benign pleomorphic adenoma at the age of 46. Her salivary gland tumor was excised and normal follow up appointments occurred. Practical Implications: Pleomorphic adenomas most commonly affect the parotid gland, the largest of the three major salivary gland tumors. Occurrence and excision of this salivary gland tumor will cause a decrease in the secretion of saliva, leading to a dry mouth and an increased risk of caries.

scholarly journals A clinical study of the incidence of salivary gland tumors in a tertiary care teaching hospital

2019 ◽  
Vol 6 (6) ◽  
pp. 2110
Author(s):  
Sathish Babu N. ◽  
Naveen H. Mahadev ◽  
Kumar G. V.
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Critical Role ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Salivary Gland Tumour ◽  
Major Salivary Gland ◽  
Salivary Gland Tumours ◽  
Gland Tumour

Background: The salivary gland system of the upper aero digestive tract plays a critical role in the functions of digestion, respiration, communication, and overall homeostasis. The Salivary gland swellings can be broadly classified into inflammatory, non-inflammatory and neoplastic swellings like calculi, benign tumours such has pleomorphic adenoma, oncocytoma, Warthin's tumour, malignant tumors which include-adenocarcinoma, adenoid cystic carcinoma, undifferentiated carcinoma.Methods: The present cross-sectional study was conducted at the Department of general surgery, Sri Siddhartha Medical College over a period of 2 years from August 2016 to July 2018.  All major salivary gland neoplastic swellings confirmed by FNAC were included in this study.Results: In our study 23 patients had major salivary gland tumours out of that 19 patients had parotid and 4 had submandibular major salivary gland tumour. In our study out 23 cases of salivary tumours 19 cases were benign and 4 cases were malignant, out of 19 cases of parotid tumours, 15 (78.94%) cases were seen in superficial lobe and 4 (21.06%) were in deep lobe, out of 23 salivary gland tumours, 19 (82.6%) cases were pleomorphic adenoma 3(13.05%) cases were mucoepidermoid carcinoma and one case (4.35%) was acinic cell carcinoma.Conclusions: Parotid gland was the most common site of origin of both benign and malignant tumours, Pleomorphic adenoma was the most common benign salivary gland tumour and mucoepidermoid carcinoma was the most frequent malignant neoplasm.

scholarly journals Management of salivary gland neoplasm – study of 32 cases

2010 ◽  
Vol 9 (2) ◽  
pp. 87-94 ◽  
Author(s):  
Md Abdullah Hel Kafi ◽  
Md Arif Hossain Bhuyan ◽  
Md Jahangir Hossain Bhuiyan ◽  
MS Khurshid Alam
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Histopathological Examination ◽  
Medical Science ◽  
Surgical Excision ◽  
Military Hospital ◽  
Salivary Gland Neoplasm ◽  
Salivary Gland Tumours ◽  
Presenting Symptoms ◽  
Parotid Neoplasm

Objective: To study the clinical, radiological and histopathological characteristics along with the management outcome of salivary gland neoplasm. Materials and Methods: This study included thirty two patients (16 male and 16 female) with salivary gland tumours presented at Combined Military Hospital Dhaka, Apollo Hospital Dhaka and Ibn Sina Medical College and Hospital Dhaka from January 2006 to December 2009. The data of each patient included age, sex, presenting symptoms and signs, provisional diagnosis, preoperative investigations, operation notes, histopathological examination and state at follow up. Results: The mean age was 42.5 years. 14 (43.75%) patients presented at 5th decade. Main presenting symptom was swelling (100%) followed by pain (18.75%). All patients underwent fine needle aspiration cytology which was conclusive in 26 patients (81.25%). Thirty one patients underwent surgical excision. 24 cases were parotid neoplasm and 8 cases were submandibular neoplasm. 20 patients (16 parotid and 4 submandibular) were pleomorphic adenoma. Conclusion: There is no substitute for detailed clinical history and examination in the assessment of salivary gland neoplasm. Imaging studies are probably academic but determine the extent of the disease. Early diagnosis, adequate and proper treatment improves the prognosis. Key words: Salivary gland tumour; Pleomorphic adenoma; Warthin's tumour; Adenoid cystic carcinoma; Mucoepidermoid carcinoma. DOI: 10.3329/bjms.v9i2.5656Bangladesh Journal of Medical Science Vol.09 No.2 Apr 2010 pp.87-94

scholarly journals Histopathological Analysis of Neoplastic and Non Neoplastic Lesions of Salivary Gland – A Retrospective Study in a Tertiary Care Hospital

2021 ◽  
Vol 8 (05) ◽  
pp. 236-240
Author(s):  
Sheela K.M ◽  
Priya V.S. ◽  
Lali K. Rajan ◽  
Ashida M. Krishnan
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Histopathological Analysis ◽  
Low Grade ◽  
Care Hospital ◽  
Neoplastic Lesions

BACKGROUND Salivary gland lesions constitute less than 1 % of tumours and about 4 % of all epithelial neoplasms of head and neck region. These comprise of a wide variety of benign, malignant and non-neoplastic lesions which exhibits a difference in histological behaviour. There are no reliable criteria to differentiate on clinical grounds the benign from malignant ones. So morphological evaluation is necessary. We aim to study the frequency of various salivary gland lesions in sialoadenectomy specimens and categorise them into neoplastic and nonneoplastic lesions. METHODS It is a record based retrospective 5-year study carried out in the Government Medical College, Thiruvananthapuram, Kerala, from January 2014 to December 2018. RESULTS In this study a total of 329 histopathologically proven cases of salivary gland lesions were included. Neoplastic lesions and non-neoplastic lesions constituted 78.42 % and 21.58 % respectively. Pleomorphic adenoma was the most common neoplasm (50.54 %) trailed by Warthin’s tumour (9.73 %). Most common malignant neoplasm encountered in our study was mucoepidermoid carcinoma (9.73 %) among which low grade tumours showed predominance. We observed significantly higher incidence of benign and malignant lesions in the 5 th to 6th decade while non neoplastic lesions were seen more in the 4th to 5th decade. Average age of the patients with salivary gland tumours was 46.12  SD 15.57. Majority of cases of salivary gland lesions in our study were from parotid gland (75.68 %) followed by submandibular gland 24.01 %. CONCLUSIONS Pleomorphic adenoma was the most common benign tumour in our study and mucoepidermoid carcinoma the most common malignant tumour. Neoplastic lesions showed a predominance over non neoplastic lesions. Histopathological examination is the mainstay for diagnosis and clinical management. KEYWORDS Histopathology, Pleomorphic Adenoma, Mucoepidermoid Carcinoma

scholarly journals Major Salivary Gland Tumors: A Clinicopathological Study

2013 ◽  
Vol 5 (1) ◽  
pp. 43-45
Author(s):  
Mohammad Wahiduzzaman ◽  
Nilima Barman ◽  
Tawfiqur Rahman ◽  
Mohammad Ehasun Uddin Khan ◽  
Mohammad Touhidul Islam ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Gland Tumor ◽  
Malignant Neoplasm ◽  
Salivary Gland Tumors ◽  
Medical College Hospital ◽  
Salivary Gland Neoplasm ◽  
Major Salivary Gland ◽  
College Hospital ◽  
Medical College ◽  
Parotid Neoplasm

Background: Major salivary gland tumors comprise a morphologically diverse group of rare tumors. The tumors also have variations in their clinicopathological profile related to racial and geographic differences. Objective: To find out the frequency of different types of major salivary gland neoplasm. Methodology: This cross sectional study was carried out on 50 patients having major salivary gland tumor in the departments of Otolaryngology of Bangabandhu Sheikh Mujib Medical University, Dhaka Medical College Hospital and Sir Salimullah Medical College Hospital from January 2010 to September 2010. Result: In this study, most cases occur in 5th decade. Incidence of malignant and benign parotid neoplasm was found 23.8% and 76.2% respectively. Benign and malignant tumors of submandibular gland were 50% in each group. No sublingual gland neoplasm was found in this group. Conclusion: Parotid gland was the most common site of origin of both benign and malignant tumours. Plemorphic adenoma was the most common benign salivary gland tumour and mucoepidermoid carcinoma was the most frequent malignant neoplasm. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16250 J Shaheed Suhrawardy Med Coll, 2013;5(1):43-45

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