scholarly journals 2–4 mm diameter hypo/depigmented dermal spots: ? Objective sign of somatic origin pain

2018 ◽  
Vol 32 (2) ◽  
pp. 72
Author(s):  
Kritika Doshi
Keyword(s):  
2021 ◽  
pp. 229255032110485
Author(s):  
Tyler Safran ◽  
Abdulaziz Alabdulkarim ◽  
Rafael Galli ◽  
Mirko S. Gilardino

Timing of extubation on post-mandibular distraction osteogenesis (MDO) surgery is critical, given that at baseline these infants have difficult airways and failed extubation requires either re-intubation of an already complex airway with a fragile, recently osteotomized mandible, or adjunctive airway measures such as CPAP that may apply unwanted pressure to the surgical site. Thus, the goal is to plan extubation when the risk of failure is minimal. Currently, there is a void in the literature addressing the timing of extubation post-MDO and no objective sign of extubation readiness has been elucidated. This study describes a simple clinical pearl to assist in the evaluation of extubation readiness in these patients. Postoperatively, we obtain weekly radiographs to assess distractor stability and advancement, and to assess for the “Air Sign”. The Air Sign describes a radiolucent space (air) visualized in the oropharynx on lateral radiographs, likely indicating that the tongue based airway obstruction has been relieved by mandibular advancement.


Blood ◽  
1984 ◽  
Vol 64 (2) ◽  
pp. 559-563 ◽  
Author(s):  
ME Fabry ◽  
L Benjamin ◽  
C Lawrence ◽  
RL Nagel

Abstract The etiopathologic basis of painful crisis in sickle cell anemia is largely unknown, and no objective criteria for its diagnosis and follow- up exist at present. We have studied 11 patients through 14 painful crises and observed a significant decrease of the densest fraction of red cells in 12 of the 14 crises as determined by isopycnic Percoll- Stractan continuous density gradients. If the first observation is normalized to 100%, the average decrease in dense cells was 77% with a range of 36% to 94%. The time needed for the percentage of dense cells to return to the steady-state level varied from seven to more than 30 days. These findings were in sharp contrast to the stability of the density pattern observed in another group of sickle cell patients, who were studied during crisis-free periods. The mechanism of the disappearance of dense cells could involve selective destruction by the reticuloendothelial (RE) system, selective sequestration in the areas of vasoocclusion, or a combination of both factors.


Author(s):  
Oluwagbenga Ogunfowokan

Background: Mortality amongst in-hospital patients bitten by carpet viper in northern Nigeria has reduced, related to use of a monospecific ovine Fab snake antivenom. However, many victims survive with temporary or permanent morbidity. Objectives: Study objectives were to: (1) determine and score the morbidity caused by carpet viper bite; and (2) find the relationship between bite-to-hospital time and morbidity amongst victims of carpet viper bite.Method: A prospective study was conducted in a rural hospital in north-central Nigeria. The morbidities scored were oedema, tenderness, prolonged whole-blood clotting time, blister, ulcer, need for blood transfusion, coma, hypotension, convulsion, length of hospital stay, need for disarticulation, and need for skin graft. A score of one was given to each objective sign. The bite-to-hospital time of 233 subjects was obtained. Descriptive and inferential statistical analysis was done.Results: Most of the subjects (150 or 64%) came to the hospital within 6 hours of the snake bite, with 2 (1%) arriving within 1 hour. The median bite-to-hospital time was 5 hours, with a range of 0.5–216 hours. Major morbidities were oedema, seen in 212 (91.0%; 95% CI 86.6–94.3%); incoagulable blood, seen in 205 (88%; 95% CI 83.1–91.9%), and tenderness, seen in 201 (86.3%; 95% CI 81.2–90.4%). The mean morbidity score was 8 ± 4. For every unit increase in logged bite-to-hospital time, the morbidity score increased by 1.85 (p < 0.001).Conclusion: Morbidity caused by carpet viper bite is high in Zamko, north-central Nigeria, and correlates with increasing bite-to-hospital time.


2016 ◽  
Vol 9 (8) ◽  
pp. 1
Author(s):  
Mohammad Zadeh Asl Mohammad ◽  
Manoochehr Tabatabei Motameni ◽  
Heibatollah Najandimanseh ◽  
Hoseein Masudniya ◽  
Manoochehr Tavasoli Naini

<p>Administrative decentralization is one of the most marvelous achievements of public laws in current age. Obviously, based on the title of the book namely Islamic Councils, we mean a certain type of local decentralization is shaped by geographical areas. In modern administrative laws, decentralization is raised in two geographical and technical aspects. Local councils are objective sign of geographical decentralization and legal figures of public laws such as universities are instances of technical decentralization.</p>In this concept, decentralization is shaped by two concepts of “managerial independence” and “elective decision making authority”. In modern administrative system, decentralization means to increase the authorities of elected officials whose proficiencies are assignable only in a region of the country. Before getting familiar with such great achievement, we should address the philosophy governing decentralization and its status in modern democracies.


Author(s):  
V. K. Koryttsev ◽  
S. V. Dergal ◽  
E. V. Frolova

The article is devoted to the treatment of patients with hiatal hernia. The aim of the study was to develop a method for diagnosing the failure of the fundoplication cuff in patients with recurrent hernia of the foodwater orifice of the diaphragm after Nissen fundoplication. The study included 42 patients. The first group consisted of 16 people with recurrent hiatal hernia. The second group consisted of 26 people without recurrence of hiatal hernia. When comparing groups of patients, a simple and objective sign of the failure of the fundoplication cuff after Nissen surgery is described. 


2021 ◽  
Vol 71 (1) ◽  
pp. 34-39
Author(s):  
Hassan Sajjad Rathore ◽  
Shahzad Saeed ◽  
Ahsan Mukhtar ◽  
Umar Ijaz ◽  
Asad Habib ◽  
...  

Objective: To compare the efficacy of tacrolimus 0.03% ointment to olopatadine 0.2% eye drops in the treatment of vernal keratoconjunctivitis. Study Design: Prospective cross-sectional study. Place and Duration of Study: Eye Department Combined Military Hospital Quetta, from Feb to Jul 2019. Methodology: A total of 69 patients with active vernal keratoconjunctivitis (VKC) were included in this study.Thirty six (52.17%) patients were randomized in tacrolimus group and 33 (47.83%) in olopatadine group B.Baseline values of the subjective symptom score (SSS) and the objective sign score (OSS) were noted. Patientswere reviewed on weeks 2, 4, 8 and 12 and the scores at each visit were summed. These scores were used forcomparison between groups. Results: At the start of the study, the mean subjective symptoms score and objective sign score of group A was 9.0 ± 2.04 and 3.93 ± 1.93 respectively, while that of group B was 8.88 ± 2.18 and 4.36 ± 1.90 respectively. At the end of 12-weeks, the mean subjective symptoms score and objective sign score of group A reduced to 0.11 ± 0.32 and 0.08 ± 0.28 respectively, while that of group B reduced to 1.70 ± 0.77 and 0.64 ± 0.55 respectively. Total improvement of scores (as a percentage of baselines) among tacrolimus group was 98.3% and olopatadine group was 83%. Conclusion: Although both 0.03% tacrolimus and 0.2% olopatadine were effective in improving the signs andsymptoms of VKC, 0.03% tacrolimus was significantly superior.


Angiology ◽  
1964 ◽  
Vol 15 (10) ◽  
pp. 434-435 ◽  
Author(s):  
C. Newton Peabody
Keyword(s):  

2008 ◽  
Vol 39 (4) ◽  
pp. 191-193 ◽  
Author(s):  
E. Niedermeyer

A prominent theta rhythm dominates the EEG of rodents such as rabbits, rats and mice. This rhythmical activity is preponderant in the hippocampus and may become quite widespread; it is usually arousal-related and generated by cholinergic mechanisms. This pattern has been intensively studied by experimental neuroscientists but is rather little known in circles of clinical electroencephalographers. Hippocampic theta rhythm is also found in canines and felines but at a clearly lesser degree and is practically absent in monkeys and humans. An olfactory memory of the macrosmatic rodents helps us understand “the world in which they live,” their EEG patterns being an objective sign of their neuropsychology.


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