scholarly journals Paradoxical reactions in spinal tuberculosis: A case series

2021 ◽  
Vol 4 (2) ◽  
pp. 176
Author(s):  
NitinP Jaiswal ◽  
GautamR Zaveri
Author(s):  
DR Gayathri Devi ◽  
B Rama Soujanya ◽  
Ashok Kumar Padmanabhan ◽  
SR Mangala Gouri ◽  
M Mahesh

Spinal Tuberculosis (TB) is the most common destructive form of extrapulmonary TB. The diagnosis of spinal TB is challenging involving combined approach of clinical diagnosis, imaging techniques, detection of acid-fast bacilli in microscopy, histopathology, and culture. This case series reports four patients of spinal TB diagnosed clinically, radiologically and microbiologically that were treated appropriately with standard anti-TB treatment according to Category I daily regimen.


Cureus ◽  
2019 ◽  
Author(s):  
Anudariya Dean ◽  
Stephanie Zyck ◽  
Gentian Toshkezi ◽  
Michael Galgano ◽  
Satya Marawar

2017 ◽  
Vol 26 (12) ◽  
pp. 3170-3177 ◽  
Author(s):  
Ashok K. Rathod ◽  
Vishwajeet Singh ◽  
Prateek Patil ◽  
Hemant Singh

2020 ◽  
pp. 219256822097361
Author(s):  
Sudhir Srivastava ◽  
Aditya Raj ◽  
Sunil Bhosale ◽  
Shaligram Purohit ◽  
Nandan Marathe ◽  
...  

Study Design: Retrospective analysis of case series. Objective: The aim is to study the recovery of neurological deficit in pediatric spinal tuberculosis cases presenting to us more than 6 months after onset of motor weakness in lower limbs. Methods: This is a retrospective analysis of 13 consecutive patients of pediatric spinal tuberculosis presenting to us at least 6 months after the onset of neurologic deficit. All these patients underwent surgical intervention at our center and their neurological recovery was noted in terms of improvement in Frankel grading and spasticity improvement by modified Ashworth scale. All the patients were followed up to at least 18 months post op and final neurologic status was assessed at that time. Results: The mean age of the patients at presentation was 8.5 years. The mean duration of neurologic deficit at the time of presentation was 10.23 months (6-24 months). Seven patients had a Frankel grade B at presentation out of which 6 improved to Frankel grade D and one improved to Frankel C at final follow up. Out of the other 3 patients with Frankel A at presentation, 2 improved to Frankel grade D and 1 to Frankel grade C. The remaining 3 patients presented with Frankel grade C at presentation, 2 improved to Frankel D and one improved to Frankel E at the time of final follow up. Conclusion: Neurologic recovery in patients with neurological deficit is possible even in cases of long standing deficit more than 6 months and in some cases upto 24 months as shown in our study.


2020 ◽  
Author(s):  
Qi Wang ◽  
Xiaobo Luo ◽  
Chi Wang ◽  
Wenhao Hu ◽  
Litao Li ◽  
...  

Abstract Background: Surgeons have been successfully handle with spinal tuberculosis via conservative or surgical treatment. However, There are quite few classifications or scoring systems concerning spinal tuberculosis to guide the surgeons to manage the complicated pattern of spinal tuberculosis. The purpose of this study is to design a practical, yet comprehensive, severity scoring system for spinal tuberculosis that helps in clinical decision-making in terms of the need for operative versus non-operative management.Methods: A group of 129 spinal tuberculosis cases (70 male and 59 female patients) successfully treated and followed up for at least 2 years were retrospectively reviewed. Clinical spine experts from our institutions were gathered to confirm the information they considered pivotal in the communication of spinal tuberculosis and the clinical decision-making process. Typical spinal tuberculosis patterns were reviewed and reconsidered in view of these essential characteristics. An initial validation process to determine the reliability and validity of this system was also undertaken. Results: A new severity scoring system was designed based on three essential characteristics: 1) the stability of spinal infectious segments determined by imaging appearance, 2) the cause of spinal cord compression and the severity of neurologic deficit, and 3) the efficacy of the anti-tuberculosis drug therapy. A severity score was calculated from these characteristics, which divided patients into surgical and nonsurgical treatment groups. Conclusions: The severity scoring system comprehensively considers features cited in the literature including prediction of spinal stability and kyphosis deformity progression, identification of neurologic compromise and characteristics of mechanical compression of spinal cord. This classification system is intended to facilitate clinical decision-making in the management of adult spinal tuberculosis (from C3 to L5 segments) . The severity scoring system may help to improve the communication among spine surgeons. Further studies are needed to determine the reliability and validity of this system.


2019 ◽  
Vol 17 (1) ◽  
pp. 47-50
Author(s):  
Avinash Kumar ◽  
P. Das

Introduction: Pott’s spine is a destructive form of tuberculosis and accounts for approximately half of all cases of musculoskeletal tuberculosis. Spinal Tuberculosis is most often missed due to inadequate sample and lack of clinical history. Most of the Extrapulmonary tuberculosis (EPTB) can be diagnosed by Ziehl Nelson stain (ZN) only, when clinically suspected samples are adequate and optimally stained. We are reporting four case series of spinal tuberculosis diagnosed by ZN stain and confirmed by Bactec MGIT Culture. Material & Methods: These four clinically suspected spinal biopsis were received for ZN stain and MTB culture by MGIT. Results: All the four spinal biopsies were found positive by ZN stain as well as by BacTec MGIT.All the four cases were HIV negative. ESR and CRP of all four cases were raised. Discussion & Conclusion: Spinal tuberculosis can be easily diagnosed by ZN stain in resource constraint lab. Despite its common occurrence and the high frequency of long-term morbidity, there are no straight forward guidelines for the diagnosis and treatment of spinal tuberculosis. Early diagnosis and prompt treatment is necessary to prevent permanent neurological disability and to minimize spinal deformity.


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