scholarly journals The prevalence of obsessive–compulsive disorder in patients with irritable bowel syndrome: A cross-sectional study

2021 ◽  
Vol 10 (1) ◽  
pp. 50
Author(s):  
FarnazDr. Radmehr ◽  
Omran Davarinejad ◽  
Fatemeh RostamiParsa ◽  
Vahid Farnia ◽  
Mostafa Alikhani
2020 ◽  
Vol 33 (2) ◽  
pp. e100180
Author(s):  
Eram Ansari ◽  
Sudha Mishra ◽  
Adarsh Tripathi ◽  
Sujita Kumar Kar ◽  
Pronob Kumar Dalal

BackgroundPatients suffering from psychiatric disorders tend to stigmatise themselves which had been linked to poor adherence to treatment.AimsThe aim of the present study was to study internalised stigma and medication adherence and to assess the relationship between them in patients with obsessive compulsive disorder (OCD).MethodsA cross-sectional study was conducted on 112 patients diagnosed with OCD who were attending the Out-patient's department at Department of Psychiatry of a tertiary care hospital in North India. Internalised stigma and current medication adherence were assessed with Internalized Stigma of Mental Illness Scale (ISMI) and Medication Adherence Rating Scale, respectively. Yale-Brown Obsessive Compulsive Scale was used to assess the current severity of OCD symptoms. Sociodemographic and clinical details were also obtained from the patients by using a semistructured sociodemographic proforma.ResultsMost of the patients reported moderate level of internalised stigma with a mean ISMI score of 77.98 (10.82). Most of the patients were compliant while 41.96% reported poor medication adherence. Internalised stigma was negatively correlated with the current medication adherence. Current severity of OCD symptoms also showed a significant positive correlation with internalised stigma and a significant negative correlation with medication adherence.ConclusionHigh levels of internalised stigma were associated with lower adherence to treatment which suggests that internalised stigma may be a very important factor influencing medication adherence in patients with OCD.


2020 ◽  
Vol 131 ◽  
pp. 187-193
Author(s):  
Elli Koumantarou Malisiova ◽  
Iraklis Mourikis ◽  
Thodoris Chalimourdas ◽  
Nikolaos Nianiakas ◽  
Maria Michou ◽  
...  

2020 ◽  
Vol 11 (4) ◽  
pp. 7572-7576
Author(s):  
Sivabalan E ◽  
Amritha Prasad ◽  
Thirunavukarasu M

Obsessive-compulsive disorder (OCD) is a clinical syndrome whose hallmarks are excessive, anxiety-evoking thoughts and compulsive behaviours that are generally recognised as unreasonable, but which cause significant distress and impairment. Heterogeneous nature of OCD presentation makes its conceptualisation as a complicated one. Phenomenological studies are needed to understand various heterogeneity OCD. This study is intended to see various phenomenological subtypes of OCD in the local population. This is a hospital-based cross-sectional study. Two hundred consecutive OCD patients attending psychiatry OPD analysed for the various social-demographic features and phenomenological findings. In our study, 48% of the sample had only obsessions, 19% had only compulsions, while 33% had a mixed presentation, studying the subtypes, the study revealed that 36.5% of the sample who presented with fear of contamination and 11.5 % samples have an aggressive obsession and another 11.5 % samples have symmetry obsession. 28% had contamination obsessions, 9% had sexual obsessions, 7% had somatic obsessions while 9% had religious obsessions, and 6% had various types of obsessions. When compulsion was assessed, it was found to be checking 28(77.8%), cleaning 25 (69%), repeating 18(50%), counting 6(16%), ordering 4 (11%), collecting 4(11%) and miscellaneous 15(42%) when subtyped. Studying the phenomenological pattern in OCD patient would help in better understanding of the illness of the patients, it also tries to attempt the relationship between sociocultural issues and OCD. Though the neurobiology is similar in all individuals, phenomenology differs between individuals concerning gender, religion and culture.


2012 ◽  
Vol 200 (5) ◽  
pp. 381-386 ◽  
Author(s):  
Timothy R. J. Nicholson ◽  
Sumudu Ferdinando ◽  
Ravikumar B. Krishnaiah ◽  
Sophie Anhoury ◽  
Belinda R. Lennox ◽  
...  

BackgroundSymptoms of obsessive–compulsive disorder (OCD) have been described in neuropsychiatric syndromes associated with streptococcal infections. It is proposed that antibodies raised against streptococcal proteins cross-react with neuronal proteins (antigens) in the brain, particularly in the basal ganglia, which is a brain region implicated in OCD pathogenesis.AimsTo test the hypothesis that post-streptococcal autoimmunity, directed against neuronal antigens, may contribute to the pathogenesis of OCD in adults.MethodNinety-six participants with OCD were tested for the presence of anti-streptolysin-O titres (ASOT) and the presence of anti-basal ganglia antibodies (ABGA) in a cross-sectional study. The ABGA were tested for with western blots using three recombinant antigens; aldolase C, enolase and pyruvate kinase. The findings were compared with those in a control group of individuals with depression (n = 33) and schizophrenia (n = 17).ResultsPositivity for ABGA was observed in 19/96 (19.8%) participants with OCD compared with 2/50 (4%) of controls (Fisher's exact test P = 0.012). The majority of positive OCD sera (13/19) had antibodies against the enolase antigen. No clinical variables were associated with ABGA positivity. Positivity for ASOT was not associated with ABGA positivity nor found at an increased incidence in participants with OCD compared with controls.ConclusionsThese findings support the hypothesis that central nervous system autoimmunity may have an aetiological role in some adults with OCD. Further study is required to examine whether the antibodies concerned are pathogenic and whether exposure to streptococcal infection in vulnerable individuals is a risk factor for the development of OCD.


BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S270-S270
Author(s):  
Khadija Mazhar ◽  
Fatima Khaliq ◽  
Daneyal Arshad

AimsObsessive-Compulsive Disorder (OCD) is an anxiety disorder, which is the sixth largest contributor to non-fatal health loss globally. Coronavirus disease (COVID-19) pandemic, aside from its impact on physical health, has also had its effects on mental health. This study aimed to explore the frequency of new onset OCD symptomology in medical students amidst COVID-19 pandemic and its association with potential sociodemographic parameters.MethodThis cross-sectional study was conducted among medical students studying in Pakistani medical colleges. Data were collected after ethical approval from 1st January 2020 to 20th January 2020 during the second COVID-19 wave. Participants with a history of diagnosed psychiatric illness such as OCD, bipolar disorder, depression, anxiety and those taking relevant medications were excluded from the study. The online questionnaire included Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and Revised Padua Inventory-Contamination Subscale (PI-CS), which were used to assess OCD symptoms and aversion for contamination respectively. Participants filled Y-BOCS twice, once for pre-pandemic score (based on self-recall), and a second time during 2nd wave of COVID-19. Data were analysed using IBM SPSS v23.0 (Armonk, N.Y., USA).ResultThe study included 711 participants (Males: 29.8%, Mean age: 21.59 ± 1.52 years) from over 46 medical colleges and over 44 cities of Pakistan. The mean pre-pandemic and mid-2nd wave Y-BOCS scores were 11.86 ± 6.02 and 15.61 ± 7.41 respectively. The mean PI-CS score was 17.27 ± 9.17. Twenty five percent (n = 176) of students developed new onset OCD symptomology during pandemic, while seventy percent (n = 497) suffered from worsened Y-BOCS score during pandemic. New onset OCD symptomology was associated with age less than 20 years (p = 0.02), higher PI-CS score (p = 0.001) and studying in preclinical years (p = 0.002). Worsening of YBOCS score had significant association with female gender (p = 0.02), attending pandemic related awareness seminar (p = 0.027), studying in preclinical years (p < 0.001) and age less than 20 years (p < 0.001). High Padua scorers (16 and above) showed significant association with increase in YBOCS score (p < 0.000), age less than 20 years (p = 0.005), preclinical years (p = 0.001), frequency of engagements in pandemic related discussions (p = 0.001) and change in YBOCS score (p < 0.001).ConclusionOur findings indicate that the prevalence of OCD symptomology increased during the COVID-19 pandemic as demonstrated by increased Y-BOCS scores.Femal medical students and students in preclinical years are more likely to suffer from psycological impact of COVID-19 pandemic and heightened concerns and fear for contamination.


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