BIOTIN BIOAVAILABILITY FROM PROTEIN SUPPLEMENTS AND CEREAL GRAINS FOR WEANLING PIGS
The biological availability of biotin in canola meal (CM), cereal grain, cereal grain plus CM, and soybean meal (SBM) was estimated, using 140 pigs in the 10- to 20-kg weight range. In exp. I, pigs (six/treatment) were individually housed and fed a basal casein-cornstarch diet with 0, 50, 100, 150, 200 or 250 μg d-biotin kg−1 to generate data for a dose-response curve based on plasma biotin concentration. Other pigs were fed CM, SBM or soyprotein isolate (SPI) included in the diet. In exp. II, pigs were housed in pairs and four pairs were fed diets based on cereal grain or cereal grain plus CM. Results (exp. I) showed a higher correlation between daily biotin intake and plasma biotin (r = 0.835, P < 0.01) than on growth rate (r = 0.627, P < 0.05). The regression for plasma biotin (Y) on biotin intake (X) computed from the linear portion of the curve (i.e., 0-200 μg added biotin kg−1) was[Formula: see text]Biotin bioavailability in various feedstuffs was highest for corn (101.2%), followed by SBM (85.5%), CM (70.9%), and wheat (33.3%), triticale (25.9%), sorghum (25.1%) and barley (24.0%). Key words: Biotin bioavailability, protein supplements, cereal grains, swine