scholarly journals 3D stereophotogrammetric analysis of lip and nasal symmetry after primary cheiloseptoplasty in complete unilateral cleft lip repair

2011 ◽  
Vol 49 (5) ◽  
pp. 546-553
Author(s):  
Bram van Loon ◽  
Srinivas G. Reddy ◽  
Niels van Heerbeek ◽  
Koen J.A.O. Ingels ◽  
Thomas J.J. Maal ◽  
...  

Background: The aim of this study was to evaluate symmetry of the lip and nose in patients with CUCLP after primary cheiloseptoplasty (Afroze technique), in comparison to non-cleft controls. Methodology: In this prospective study, forty-four patients with operated non-syndromic CUCLP were included. The control group consisted of 44 volunteers without cleft defects of approximately the same age and sex. Primary septoplasty was performed in conjunction with the cleft lip (CL) repair using the Afroze incision. 3D facial images were acquired using 3D stereophotogrammetry. After a 3D cephalometric analysis of the lip and nose was performed in both groups, linear and volumetric data were acquired. Lip and nose symmetry were calculated and compared using Student`s t-tests as well as the Chi square test. Results: For all measurements, the control group was up to 36% closer to perfect symmetry compared to the CUCLP group after primary surgery. This difference was statistically significant. Conclusions: After primary cheiloseptoplasty according to the Afroze technique in patients with CUCLP, asymmetry in the nose and lip area still exists as compared to non-cleft controls. Although non-cleft individuals also show some degree of asymmetry, the results of this study stress the difficulty in obtaining near normal symmetrical relations.

2011 ◽  
Vol 49 (5) ◽  
pp. 546-553
Author(s):  
Bram van Loon ◽  
Srinivas G. Reddy ◽  
Niels van Heerbeek ◽  
Koen J.A.O. Ingels ◽  
Thomas J.J. Maal ◽  
...  

Background: The aim of this study was to evaluate symmetry of the lip and nose in patients with CUCLP after primary cheiloseptoplasty (Afroze technique), in comparison to non-cleft controls. Methodology: In this prospective study, forty-four patients with operated non-syndromic CUCLP were included. The control group consisted of 44 volunteers without cleft defects of approximately the same age and sex. Primary septoplasty was performed in conjunction with the cleft lip (CL) repair using the Afroze incision. 3D facial images were acquired using 3D stereophotogrammetry. After a 3D cephalometric analysis of the lip and nose was performed in both groups, linear and volumetric data were acquired. Lip and nose symmetry were calculated and compared using Student`s t-tests as well as the Chi square test. Results: For all measurements, the control group was up to 36% closer to perfect symmetry compared to the CUCLP group after primary surgery. This difference was statistically significant. Conclusions: After primary cheiloseptoplasty according to the Afroze technique in patients with CUCLP, asymmetry in the nose and lip area still exists as compared to non-cleft controls. Although non-cleft individuals also show some degree of asymmetry, the results of this study stress the difficulty in obtaining near normal symmetrical relations.


2015 ◽  
Vol 26 (6) ◽  
pp. 561-565 ◽  
Author(s):  
Márcia Waltrick-Zambuzzi ◽  
Patricia Nivoloni Tannure ◽  
Thays Cristine dos Santos Vieira ◽  
Leonardo Santos Antunes ◽  
Fábio Lourenço Romano ◽  
...  

The aim of this study was to evaluate the association of the polymorphisms in TCN2 (rs1801198) gene and in MTRR (rs1801394) gene with nonsyndromic cleft lip and/or palate (NSCL/P) in a Brazilian population. Genomic DNA was extracted from buccal cells. The polymorphisms in TCN2 (rs1801198) and MTRR (rs1801394) genes were genotyped by carrying out real-time PCR and Taqman assay. Chi-square test was used to determine the association between genotype and allele frequencies with NSCL/P and NSCL/P subgroups (cleft lip only, cleft lip and palate, and cleft palate only). Eight hundred and sixty seven unrelated individuals (401 cases with NSCL/P and 466 individuals without cleft) were evaluated. Genotype distributions of TCN2 and MTRR polymorphisms were in Hardy-Weinberg equilibrium. The TCN2 polymorphic genotype GG was identified in 16.7% of the NSCL/P group and in 14.1% of the non-cleft group (p>0.05). Similarly, the frequency of MTRR genotype (GG) was similar in NSCL/P group (15.5%) and control group (17.8%) (p>0.05). Multivariate analysis showed an association between MTRR and the subgroup that the mother smoked during pregnancy (p=0.039). Our findings did not demonstrate an association between TCN2 polymorphisms and NSCL/P, however suggests an association between MTRR and NSCL/P etiology


2020 ◽  
Vol 28 ◽  
pp. 03003
Author(s):  
Nandini Anindita Sumitro ◽  
Wiwin Winda Kusumadewi ◽  
Fitri Yuniawati ◽  
Naila Amalia ◽  
Hendrawati Hendrawati ◽  
...  

Platelet-rich plasma (PRP) rich in growth factors has evolved as an important therapy for periodontal tissue regeneration. A healthy blood donors obtained for homologous PRP (h-PRP). The Freeze-drying h-PRP sample provides an effective method to ensure a longer shelf-life. The h-PRP samples are subjected to crossmatch testing in clinics to prevent any immune response in recipients. The present study aimed to evaluate the differences in donor compatibility on crossmatch test results towards fresh and freeze-dried h-PRP (FD h-PRP). This was a laboratory experiment, h-PRP prepared according to the protocol of blood bank, and 40 recipients blood samples divided into two groups, fresh h-PRP (control group) and FD h-PRP. The crossmatch test was performed to evaluate h-PRP compatibilities by using the gel-test method. The data were analyzed using the chi-square test. The results of the study showed that the crossmatch test on FD h-PRP samples was 100 % compatible and could increase the compatibility results of the donor. the FD h-PRP was safe to become donors and clinical applications.


2020 ◽  
Vol 8 (3) ◽  
pp. 396
Author(s):  
Nurasih Nurasih ◽  
Endang Nurrochmi

In Indonesia, Yoga is currently one of the most popular sports, not only for the general public but also for pregnant women. Many benefits can be obtained from prenatal yoga including the mother feeling comfortable and relaxed throughout pregnancy and during childbirth, training the pelvic floor muscles and perineum, keeping the body's muscles relaxed, balanced during childbirth, reducing stress, increasing and improving oxygen circulation to the body and fetus. . This study aims to determine the effect of prenatal yoga on optimizing fetal position on third trimester Primigravida maternal delivery output at Puskesmas Cirebon City. This research is a quasi-experimental research pre post control group design and only post control group design with T test and Chi Square test. Paired T Test results of the intervention group (mean difference = 3.111, P value = 0.000, control group (mean difference = 0.833, P value = 0.318). Independent T Test results obtained (average difference = -1.944, P value = 0.024), Chi Square test obtained a value of P = 0.73. There is a difference in the average anxiety before and after the intervention in the intervention group, there is no difference in average anxiety before and after the intervention in the control group. There is a difference in the average anxiety between the intervention and control groups. There is a difference in mean Long I stage between the intervention and control groups There was no effect of prenatal yoga on the type of labor.


2021 ◽  
Vol 24 (4) ◽  
Author(s):  
Kelly Fernanda Molena ◽  
Vivian Patricia Saldias Vargas Winckler ◽  
Gisele da Silva Dalben

Objective: Congenital defects, including cleft lip and palate, increase the morbidity and mortality in the affected population. This study aimed to determine the prevalence of cleft lip and palate in the city of Bauru, Brazil, by evaluation of registry in the Brazilian Livebirth Certificate (DNV) and the Information System on Livebirths (SINASC), and analyzed the concordance of diagnosis compared with registries of the Hospital for Rehabilitation of Craniofacial Anomalies (HRAC/USP), located in the same city. Material and Methods: This retrospective observational study comprised analysis of all DNVs and identification of individuals with clefts born and living in Bauru, comparing with data from HRAC/USP. The prevalence was calculated by dividing the number of children born with clefts in the study period by the total number of livebirths registered. The reporting of different types of clefts was compared by the chi-square test. Results: Overall, 50,898 DNV were evaluated, among which there were 25 reported cases of cleft lip and/or palate. In the same period, HRAC/USP registered 77 cases born in Bauru, representing 67.5% of underreporting of the occurrence of clefts. Cleft palate was the most prevalent (34.9%), followed by cleft lip and palate (31.7%) and cleft lip (30.2%), mostly affecting males (58.5%). The reporting of cleft palate (16.12%) was lower compared to cleft lip (43.75%) and cleft lip and palate (54.54%). Conclusion: The study revealed predominance of cleft palate, with significant underreporting of clefts in the public health system, especially for cleft palate as compared to cleft lip and cleft lip and palate. Keywords Cleft lip; Cleft palate; Epidemiology; Prevalence; Reporting.


2002 ◽  
Vol 39 (1) ◽  
pp. 36-39 ◽  
Author(s):  
Nicola Mannucci ◽  
Ornella D'orto ◽  
Federico Biglioli ◽  
Roberto Brusati

Objective To achieve closure of wide unilateral cleft lip repair without tension of the cleft lip margins, a large undermining, especially of the anterolateral surface of the maxilla, is needed. Two types of dissection are feasible: supraperiosteal or subperiosteal. The aim of this study was to investigate whether there are differences in maxillary growth between healthy rabbits after supraperiosteal or subperiosteal dissection. Methods Twenty-four male 7-week-old New Zealand white rabbits were divided randomly into three groups: eight control animals (untreated); eight animals undergoing supraperiosteal dissection of the left surface of the maxilla, and eight animals undergoing subperiosteal dissection of the left surface of the maxilla. All of the treated animals were operated on by the same surgeon at age of 7 weeks and sacrificed at 27 weeks together with control group animals. Seven cephalometric measures (representing aspects of maxillary length, width, and height), on the left side, were taken on the cleaned skull of the rabbits, and the results were analyzed statistically. Results No significant differences in maxillary growth were noted across the three study groups. Conclusions The supraperiosteal or subperiosteal undermining of the anterolateral surface of the maxilla does not seem to interfere with the growth of the normal maxilla in the rabbit.


2010 ◽  
Vol 17 (02) ◽  
pp. 340-346
Author(s):  
WAJID ALI AKHUNZADA ◽  
RAZA UR RAHMAN ◽  
IMTIAZ AHMAD DOGAR ◽  
Niaz Maqsood

Objectives: To determine the different levels of drug non-adherence in patients suffering from Depression. Design: A casecontrolled study. Place and Duration of Study: Hayatabad Medical Complex Peshawar, From February 2008 to August 2008. Patients and Method: 50-Cases were selected from the out patient department with the DSM-IV diagnosis of major depressive disorder, 50- non psychotic patients were selected as controls. Both sexes were included. The basic socio-demographic characteristics and the clinical profile of all the patients were collected. The level of drug non-adherence was recorded at week 4, week 8 and week 12. SPSS version 15 was used for statistical analysis. The applied method for group comparison was the Chi-square test. Results: The age in mean was 33.78 ± 11.30 for the sample and 30.65 ± 9.40 for control group. 38% of these patients were males and 62% females. 58% were married and uneducated from lowersocio-economical class. 70% of the study group and 59% of control group received treatment. The rates of non adherence were statistically not significant at week 4. However, at week 8 and week 12 the rates of non adherence were statistically significant with the p values of less than (0.001) respectively. Discussion: Rates of non-adherence with psychotropic / antidepressants are difficult to summarize because they varywith setting, diagnosis, severity of illness and type of adherence difficulties. Drug non-adherence is a serious clinical problem and it has direct effects on illness management and prognosis. Conclusions: The available evidence suggests that the outcome for patients who vary medication doses without consulting a professional is poor. 


2014 ◽  
Vol 2 (4) ◽  
pp. 353
Author(s):  
Kodanda Ram ◽  
Anila Karunakaran ◽  
Aneesh Sebastian ◽  
Muqthadir Siddiqui ◽  
Mohammed Shafi

AIM: To assess the dental findings among fishermen communities residing in the coastal areas of Edakkad and Muzhappilangad, Kannur, Kerala, South India, and the feasibility of using these findings for identification of the subjects in forensic investigation. MATERIAL AND METHODS: Fifty males of age group 30-35 years were selected- two groups of 20 each from two fishermen communities and one control group of 10 from the non- fishermen population. The parameters included in the study were work procedure, smoking, tobacco chewing, alcohol consumption, attrition, cervical abrasion, macrodontia, incisal notching, dental caries and facial features. For statistical analysis was used chi-square test. RESULTS: All the parameters were significantly more in the study groups compared to the controls. CONCLUSION: Further research is suggested to identify other factors which may influence the outcome of forensic investigation.


2006 ◽  
Vol 13 (03) ◽  
pp. 423-430
Author(s):  
WAJID ALI ◽  
WAJEH UR REHMAN ◽  
NIAZ MAQSOOD

Objectives: To determine the different levels of drug non-compliance inpatients with schizophrenia and to find out its relationship to relapses of the disorder and admission to the hospital.Design: A randomized, retrospective, case- controlled study. Place and Duration of Study: Conducted at GovernmentMental Hospital Peshawar, from April 2001 to December 2002. Patients and Method: 50-Cases were randomly (eachfifth patient) selected from all the admissions with the DSM-IV diagnosis of Schizophrenia, 50- matched controls wererandomly (each fifth patient) selected from the outdoor patients. Both sexes were included. The basicsociodemographic characteristics and the clinical profile of all the patients were collected. The level of drug noncompliancewith previous history of admissions to hospital and total number of relapses. SPSS version 10 was usedfor statistical analysis. The applied method for group comparison was the Chi-square test. Results: The mean age ofstudy group was 33.54 ± 8.15 years as compare to 32.56 ± 9.02 years of control group, most participants were men,and a predominant proportion of participants were married. Majority of the patients were from the lower socio-economicclass. Scores on the drug non- compliance were statistically significant with a p value of (0.027). The differencebetween the two groups, regarding the previous number of relapses was statistically significant with a p value (0.002).The number of previous admission was also statistically significant and the p value was (0.017). 74.1% of the patientswith poor drug compliance relapsed, while 71% of patients with poor compliance needed admission. Conclusion: Animportant measure of out come is compliance with treatment. A substantial proportion of patients with schizophreniacontinues to relapse and are readmitted to the hospital as a result of non-compliance to treatment.


1993 ◽  
Vol 20 (4) ◽  
pp. 647-657 ◽  
Author(s):  
Michael B. Lewis

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