scholarly journals Antibacterial Activity and Phytochemical Analysis of <i>Mentha piperita</i> L. (Peppermint)—An Important Multipurpose Medicinal Plant

2013 ◽  
Vol 04 (01) ◽  
pp. 77-83 ◽  
Author(s):  
Para Sujana ◽  
Thulasi Muneppa Sridhar ◽  
Penchalaneni Josthna ◽  
Challagundla Varadarajulu Naidu
2007 ◽  
Vol 89 (1) ◽  
Author(s):  
G. Bupesh ◽  
C. Amutha ◽  
S. Nandagopal ◽  
A. Ganeshkumar ◽  
P. Sureshkumar ◽  
...  

2018 ◽  
Vol 12 (2) ◽  
pp. 223
Author(s):  
Amalia Indah Prihantini ◽  
Krisnawati Krisnawati ◽  
Anita Apriliani Dwi Rahayu ◽  
Yosephin Martha Maria Anita Nugraheni ◽  
Gipi Samawandana

Euchresta horsfieldii merupakan tanaman obat yang dikenal di Nusa Tenggara Barat dan Bali sebagai pranajiwa. Pada penelitian ini telah dilakukan analisis fitokimia dan aktivitas antibakteri dari akar, batang, daun, dan biji pranajiwa. Pengujian aktivitas antibakteri dilakukan terhadap bakteri Bacilus subtilis Inacc-B334, Staphylococccus aureus Inacc-B4, dan Escherchia coli Inacc-B5. Hasil analisis fitokimia menunjukkan bahwa alkaloid sebagai komponen senyawa yang paling dominan pada pranajiwa dan terdeteksi di setiap bagian tanaman. Bagian akar pranajiwa terdeteksi memiliki komponen senyawa yang paling bervariasi seperti alkaloid, tanin, flavonoid, saponin, dan terpenoid. Analisis GC-MS dari batang, akar, dan biji pranajiwa menunjukkan mome inositol, sophoridane, dan asam lemak seperti asam palmitat dan asam stearat sebagai komponen utamanya. Adapun uji aktivitas antibakteri pranajiwa menunjukkan bagian batang dan akar memiliki aktivitas antibakteri terhadap S. aureus Inacc-B4 dan E. coli Inacc B-5, sedangkan bagian biji memiliki aktivitas antibakteri terhadap B. subtilis Inacc-B-334 dan S. aureus Inacc-B4. Hasil-hasil penelitian tersebut dapat mendukung penelitian terkait potensi E. horsfieldii sebagai sumber alternatif obat antibakteri. Phytochemical Test and Antibacterial Activity of Pranawija (Euchresta horsfieldii (Lesch.) Benn.)AbstractEuchresta horsfieldii is a medicinal plant known in West Nusa Tenggara and Bali as pranajiwa. This study investigated phytochemical analysis and antibacterial activity of roots, stems, leaves, and seeds of E. horsfieldii. The samples were analyzed for their antibacterial activity against Bacilus subtilis Inacc-B334, Staphylococccus aureus Inacc-B4, and Escherchia coli Inacc-B5. The phytochemistry result indicated that alkaloids was the most dominant constituent of E. horsfieldii as it was detected in all parts of the plant. GC-MS analysis of the stems, roots, and seeds showed mome inositol, sophoridane, and fatty acids such as palmitic acid and strearic acid as the main components. The roots had the most varied constituents with detection of alkaloids, tannins, flavonoids, saponins, and terpenoids. Further, antibacterial activity assay showed that the stems and roots had antibacterial activity against S. aureus Inacc-B4 and E. coli Inacc B-5, whereas the seeds had antibacterial activity against B. subtilis Inacc-B-334 and S. aureus InaccB4. The result of the present study supports the investigation on potentiality of E. horsfieldii as alternative source for antibacterial agents.


2021 ◽  
Author(s):  
Mathewos Agize Ante ◽  
Zemede Asfaw Woldemariam ◽  
Sileshi Nemomissa Duguma ◽  
Tizazu Gebre Alemayehu ◽  
Mathewos Anza Alemu ◽  
...  

Abstract Introduction: For generations, many plants were extracted to find drugs and to discover novel and new chemical structures from extracts. Maerua oblongifolia (Forsk.) A. Rich, “Sangganaa” in Dawuro language is a locally threatened traditional medicinal plant, which is traditionally used to treat diarrhea. The present study aimed to check the chemical contents of the different plant parts for possible shifting of the extensive use of the root to other parts of the plant.Methods: Phytochemical screening tests were carried out by standard procedures to investigate various classes of secondary metabolites. Roots, root bark, stem bark, and leaves were extracted by maceration in aqueous and ethanol to get crude extracts. Antibacterial effect of extracts against Escherichia coli and Salmonella thypi was evaluated by the disc diffusion method. Results: The phytochemical analysis showed the presence of alkaloids, saponins, tannins, phenols, carbohydrates, and proteins in the tested parts of the plant. Antibacterial activity displayed the extracts of M. oblongifolia against tested bacteria strains in dose dependent manner. Among tested extracts, roots and stem barks ethanol extracts showed potential antibacterial activity, with zone of inhibitions (19.0 ± 1.15, 17.0 ±1.00) in 100 mg/mL, and (17.3 ± 0.57, 15.0 ± 1.00) in 50 mg/mL, respectively. Conclusion: The finding showed a possibility to shift stem bark instead of roots in the use of traditional medicinal practices to ensure conservation and sustainable use of Maerua oblongifolia. The finding also supports the traditional use of the plant’s root or stem bark for the treatment of diarrhea.


Author(s):  
Debasish Singha Roy ◽  
Subhasish Maity ◽  
Writtik Maity ◽  
Somnath De ◽  
Dulal Chandra Das

Background: There is much investigation with the Andrographis paniculata which is a very well-known medicinal plant, people were using this plant from ancient years, but this another species Andrographis echioides was not explored too much for many years. In this study we tried to find out the important phyto constitiuents, antibacterial activity and anti-inflammatory activity of this plant. Aim: The main aim of the present study, was to screen phytochemical derivatives from an Indian medicinal plant Andrographis echioides (L) Nees and to evaluate the antibacterial potential, and anti-inflammatory activity also. Study Design: Various tests or experiment was done in this study according to the review of the literature with little modification, a preliminary phytochemical screening was carried out in the plant extracts using qualitative methods. The whole plant of Anrographis echioides was subjected to soxhlet extraction using organic solvent of methanol, acetone, and petroleum ether. The antibacterial activity of acetone, methanol and petroleum ether whole plant extracts of Andrographis echioides was carried out using agar well diffusion method, anti-inflammatory activity was checked using fresh egg albumin method, and a statistical analysis was done using SPSS to prove that there is a strong correlation between the activity of our plant sample and a standard commercial drug (NASID). Place and Duration of the Study: The whole study was done in Panskura Banamali College, Vidyasagar University, Department of Biotechnology sponsored by BOOST, Louis Pasteur laboratory, West Bengal, India. The study was done between 17th August 2018 - 30th February 2019.  Results: All these tests were done triplicate and the mean value was taken. The phytochemical analysis reveals that the plant has some important phytoconstituents such as Tannins, flavonoids, phenolic compounds, glycosides and terpenoids. The Acetone and Methanol extracts are showed the best zone of inhibition against the severe pathogens such as S. aureus (A.E-33 mm, M.E-28 mm), S. typhi (A.E- 26.67 mm, M.E-28.33 mm). The methanolic extract of Andrographis echioides showed excellent anti-inflammatory activity comparing to the NASID (Non-steroidal anti-inflammatory drugs) Diclofenac sodium, it showed almost same activity. Conclusion: Experimental findings reveal Andrographis echioides is the best herbal to control specially S. typhi, E. coli, S. aureus, K. pneumoniae. The phytochemical constituents which are responsible for many pharmacological activities, may be useful for the evolution of pharmaceutical and for the therapy of ailments, and also can used as a an potent anti-inflammatory natural remedy without any side effect.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Anindya Sundar Ray ◽  
Suman Kalyan Mandal ◽  
Chowdhury Habibur Rahaman

Solanum glaucophyllum Desf. (Solanaceae) is traditionally used for curing several health conditions in both human and domesticated animals. There is no data available regarding pharmacognostic standardization and pharmacological activity of this less known medicinal plant. Therefore, the aim of the present work is to prepare pharmacognostic fingerprints of crude drugs obtained from the leaf and stem parts of S. glaucophyllum. Apart from this detailed phytochemical analysis, antioxidant and antimicrobial studies have also been carried out. Pharmacognostic study revealed that the leaves are amphistomatic and stomata are strictly of anisocytic type. Values of stomatal index, palisade ratio, ash content of the investigated parts are found distinct and can be used as pharmacognostic standards for evaluation of crude drugs of this medicinal plant. Phytochemical studies of the leaf and stem parts indicated that phenolics, flavonoids, tannins and alkaloids are present in quite impressible amount. Curcumin content in stem was found very high through HPLC analysis. In DPPH radical scavenging assay, the stem part showed significant antioxidant potential. Ethanol extract of stem produced maximum inhibition zone (11mm) against Pseudomonas aeruginosa at the concentration of 50 mg/ml among five test microorganisms. Some pharmacognostic features recorded in this study as diagnostic ones will help in proper identification of this ethnomedicinal plant in its fresh as well as dried form. On the other hand preliminary phytochemical, antioxidant and antimicrobial studies highlight the S. glaucophyllum as a promising candidate for bioprospecting.


2019 ◽  
Vol 20 (4) ◽  
pp. 285-292 ◽  
Author(s):  
Abdullah M. Alnuqaydan ◽  
Bilal Rah

Background:Tamarix Articulata (T. articulata), commonly known as Tamarisk or Athal in Arabic region, belongs to the Tamaricaece species. It is an important halophytic medicinal plant and a good source of polyphenolic phytochemical(s). In traditional medicines, T. articulata extract is commonly used, either singly or in combination with other plant extracts against different ailments since ancient times.Methods:Electronic database survey via Pubmed, Google Scholar, Researchgate, Scopus and Science Direct were used to review the scientific inputs until October 2018, by searching appropriate keywords. Literature related to pharmacological activities of T. articulata, Tamarix species, phytochemical analysis of T. articulata, biological activities of T. articulata extracts. All of these terms were used to search the scientific literature associated with T. articulata; the dosage of extract, route of administration, extract type, and in-vitro and in-vivo model.Results:Numerous reports revealed that T. articulata contains a wide spectrum of phytochemical(s), which enables it to have a wide window of biological properties. Owing to the presence of high content of phytochemical compounds like polyphenolics and flavonoids, T. articulata is a potential source of antioxidant, anti-inflammatory and antiproliferative properties. In view of these pharmacological properties, T. articulata could be a potential drug candidate to treat various clinical conditions including cancer in the near future.Conclusion:In this review, the spectrum of phytochemical(s) has been summarized for their pharmacological properties and the mechanisms of action, and the possible potential therapeutic applications of this plant against various diseases discussed.


2021 ◽  
Vol 2 (1) ◽  
pp. 23-33
Author(s):  
Abdul Aziz ◽  
Veggy Nadya Yuliawan ◽  
Paula Mariana Kustiawan

Propolis is one of the natural products produced by kelulut bees and is still not widely used. The type of stingless bee that is the prima donna in the community is Heterotrigona itama. This study aims to determine the phytochemical content of the n-hexane fraction of Heterotrigona itama bee propolis collected from Kutai Kartanegara, East Kalimantan. The n-hexane fraction was obtained from the methanol extract of H. itama propolis by the liquid-liquid partition method. After obtaining the n-hexane fraction, the research continued with a qualitative phytochemical test to identify the compound and determine total phenolic. Antibacterial activity was determined by the agar well diffusion method with a serial concentration in Escherichia coli bacteria. Qualitative phytochemical analysis in the form of color changes showed that the n-hexane fraction of H. itama propolis contained flavonoids, alkaloids, saponins, and tannins. Based on the results, the total phenolic content of the n-hexane fraction sample was 490 mgGAE/100 g. It caused the n-hexane fraction to have lower phenolic content than the methanol extract (792 mg GAE100 g). Furthermore, this result indicated that the non-polar fraction was not substantial enough to extracted phenolic compounds. It correlated to the antibacterial activity of the n-hexane fraction, which was very weak (2  mm ± 1.5) at  200µg/mL concentration.


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