scholarly journals Evaluating the Efficacy of the Supertowel™ as a Handwashing Product: A Simulation of Real-World Use Conditions

2021 ◽  
Author(s):  
Belen Torondel ◽  
Rummana Khan ◽  
Torben Holm Larsen ◽  
Sian White
Keyword(s):  
Escherichia Coli ◽  
Real World ◽  
Laboratory Tests ◽  
Crossover Design ◽  
The Other ◽  
Reference Condition ◽  
Contaminated Water ◽  
Emergency Situations ◽  
Laboratory Conditions ◽  
Handwashing With Soap

The Supertowel is a fabric treated with a permanent antimicrobial bonding and has been designed as a soap alternative in emergency situations. The Supertowel has been shown to be as efficacious as handwashing with soap and water when tested under controlled laboratory conditions. It has also been shown to be a practical, acceptable, and desirable product among crisis-affected populations. The aim of this study was to test whether the Supertowel remains as efficacious when used under conditions which mimic real-world hand cleaning in challenging settings. Two rounds of laboratory tests, with 16 volunteers in each, were conducted to test the efficacy of the Supertowel when used for a shorter duration, when less wet, when used with contaminated water, when visibly dirty, and when dry. Volunteers pre-contaminated their hands with nonpathogenic Escherichia coli. Comparisons were made between hand cleaning with the Supertowel and the reference condition (normally handwashing with soap), using a crossover design. The Supertowel was marginally less efficacious than handwashing with soap when used for 15 seconds (P = 0.04) but as efficacious at 30 and 60 seconds durations. All the other Supertowel conditions were as efficient as their reference comparisons meaning that the Supertowel can effectively remove pathogens from hands when it is wet, damp, or completely dry, when it is used with contaminated water, when visibly dirty with mud and/or oil.

Figure 1. Anmonia-binding capacity of the three litters under laboratory conditions. 4. LIQUID-BINDING CAPACITY The absorption capacity of the litter determines the amount used, and also affects the functioning of hydraulic manure presses. Hie absorption capacity of litter depends on its initial moisture content. In the laboratory tests , peat had a much greater absorption capacity than other litters. Peat absorbed a maximum of 4.5 times its own weight of liquid, straw 3.5 times, cutter shavings 3.6 times and sawdust 1.5 times (4). The litters used in the tests had an initial moisture content of 20%, with the exception of peat, which contained 40% moisture. These moisture contents represent the working values for good-quality litters. Peat was far superior in terms of absoption capacity to the other litters. Litter should retain its absorption capacity even when under pressure, for example in a hydraulic manure press. The ability of litters to withstand pressure was tested by first allowing than to absorb either water or urine. The litters were then compressed in a hydraulic press for one hour as the pressure was increased stepwise from 20 N/an2 to 50 N/an2. The pressure exerted by hydraulic manure presses in practice is around 40-60 N/cm2. All the retained urine better than water. Sawdust was found to have the greatest resistance to pressure, retaining about 75% of the absorbed

1986 ◽  
pp. 197-197
Keyword(s):  
Moisture Content ◽  
Laboratory Tests ◽  
Binding Capacity ◽  
Initial Moisture Content ◽  
Hydraulic Press ◽  
Absorption Capacity ◽  
The Other ◽  
Moisture Contents ◽  
Laboratory Conditions ◽  
Better Than

scholarly journals Research on the adaptability of vehicles with different technical types to the China 6 regulation standard

2021 ◽  
Vol 268 ◽  
pp. 01039
Author(s):  
Feng Yan ◽  
Jian Ling ◽  
Chunbei Dai ◽  
Yuewei Wang ◽  
Jingyuan Li
Keyword(s):  
Fuel Consumption ◽  
Real World ◽  
Direct Injection ◽  
The Other ◽  
Laboratory Conditions ◽  
Other Hand ◽  
Gasoline Vehicles ◽  
Conformity Factor

A test fleet including 47 gasoline vehicles with 6 different technical types was organized, and the adaptability of these vehicles under China 6 standard was studied. By analyzing the performance of the vehicles tested in laboratory and in real-world, technical types that could simultaneously reconcile emission and fuel consumption performance were proposed. The results show that all vehicles were well performed under laboratory conditions, but in real-world conditions, 50% direct injection vehicles without GPF would fail the RDE test. On the other hand, vehicles with GPF had better performance, all of which passed the RDE tests even if the conformity factor decreased from 2.1 to 1. In addition, it is found that the fuel consumption of the DI vehicles were lower than that of the PFI vehicles. As the DI vehicles with GPF showed better performance on the balance of emission and fuel consumption, indicating that they may have better potentials to deal with the increasing tightened emission and fuel consumption standards at the same time.

scholarly journals Assessment of Selected Parameters of Sowing Quality of Vistula Parsley Seeds with a Precision Seed Drill with a Pneumatic Seeding System

2020 ◽  
Vol 24 (2) ◽  
pp. 77-88 ◽  
Author(s):  
Szymon Ignaciuk ◽  
Janusz Zarajczyk
Keyword(s):  
Laboratory Tests ◽  
The Other ◽  
Laboratory Conditions ◽  
Other Hand ◽  
Special Stand ◽  
Working Section

AbstractResults of laboratory tests on the sowing quality of Vistula parsley seeds with a working section of a seed drill by Weremczuk company Max Pneumatic S 156 model with a pneumatic sowing system were presented. Tests of the sowing section of a seed drill were carried out in laboratory conditions on a special stand. They showed that the seed drill speed and rotations of the sowing disc have a significant impact on the sowing quality expressed with participation of single, double sowing and passes. The most favourable results at all set distances between seeds in a row were obtained with a seed drill speed of 1 km·h−1. On the other hand, the increase of the working speed of a seed drill and rotations of a sowing disc influenced significantly the deterioration of the sowing quality.

Infection of Escherichia coli with bacteriophages

1969 ◽  
Vol 27 ◽  
pp. 370-371
Author(s):  
Manfred E. Bayer
Keyword(s):  
Escherichia Coli ◽  
Nucleic Acid ◽  
Cell Surface ◽  
Virus Type ◽  
Infection Process ◽  
Adsorption Site ◽  
The Other ◽  
Specific Receptors ◽  
Bacterial Receptors

The first step in the infection of a bacterium by a virus consists of a collision between cell and bacteriophage. The presence of virus-specific receptors on the cell surface will trigger a number of events leading eventually to release of the phage nucleic acid. The execution of the various "steps" in the infection process varies from one virus-type to the other, depending on the anatomy of the virus. Small viruses like ØX 174 and MS2 adsorb directly with their capsid to the bacterial receptors, while other phages possess attachment organelles of varying complexity. In bacteriophages T3 (Fig. 1) and T7 the small conical processes of their heads point toward the adsorption site; a welldefined baseplate is attached to the head of P22; heads without baseplates are not infective.

The Nature of the Intramembrane Particle

1980 ◽  
Vol 38 ◽  
pp. 688-691
Author(s):  
A.J. Verkleij
Keyword(s):  
Escherichia Coli ◽  
Tight Junction ◽  
Gap Junction ◽  
The Other ◽  
Fracture Face ◽  
Band 3 Protein ◽  
Satisfactory Explanation ◽  
Freeze Fracturing ◽  
Intramembrane Particle ◽  
Luminal Membrane

Freeze-fracturing splits membranes into two helves, thus allowing an examination of the membrane interior. The 5-10 rm particles visible on both monolayers are widely assumed to be proteinaceous in nature. Most membranes do not reveal impressions complementary to particles on the opposite fracture face, if the membranes are fractured under conditions without etching. Even if it is considered that shadowing, contamination or fracturing itself might obscure complementary pits', there is no satisfactory explanation why under similar physical circimstances matching halves of other membranes can be visualized. A prominent example of uncomplementarity is found in the erythrocyte manbrane. It is wall established that band 3 protein and possibly glycophorin represents these nonccmplanentary particles. On the other hand a number of membrane types show pits opposite the particles. Scme well known examples are the ";gap junction',"; tight junction, the luminal membrane of the bladder epithelial cells and the outer membrane of Escherichia coli.

The Reliability of Retrieval-Induced Forgetting

2012 ◽  
Vol 17 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Rosalind Potts ◽  
Robin Law ◽  
John F. Golding ◽  
David Groome
Keyword(s):  
Individual Differences ◽  
Recognition Test ◽  
Laboratory Tests ◽  
The Other ◽  
Clinical Factors ◽  
Test Items ◽  
T1 And T2 ◽  
Test Materials ◽  
Induced Forgetting

Retrieval-induced forgetting (RIF) refers to the finding that the retrieval of an item from memory impairs the retrieval of related items. The extent to which this impairment is found in laboratory tests varies between individuals, and recent studies have reported an association between individual differences in the strength of the RIF effect and other cognitive and clinical factors. The present study investigated the reliability of these individual differences in the RIF effect. A RIF task was administered to the same individuals on two occasions (sessions T1 and T2), one week apart. For Experiments 1 and 2 the final retrieval test at each session made use of a category-cue procedure, whereas Experiment 3 employed category-plus-letter cues, and Experiment 4 used a recognition test. In Experiment 2 the same test items that were studied, practiced, and tested at T1 were also studied, practiced, and tested at T2, but for the remaining three experiments two different item sets were used at T1 and T2. A significant RIF effect was found in all four experiments. A significant correlation was found between RIF scores at T1 and T2 in Experiment 2, but for the other three experiments the correlations between RIF scores at T1 and T2 failed to reach significance. This study therefore failed to find clear evidence for reliable individual differences in RIF performance, except where the same test materials were used for both test sessions. These findings have important implications for studies involving individual differences in RIF performance.

Platelet Suruival and Function in Rats with Enhanced Thrombotic Tendency

1985 ◽  
Vol 54 (04) ◽  
pp. 739-743 ◽  
Author(s):  
Federica Delaini ◽  
Elisabetta Dejana ◽  
Ine Reyers ◽  
Elisa Vicenzi ◽  
Germana De Bellis Vitti ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Nephrotic Syndrome ◽  
Platelet Function ◽  
Laboratory Tests ◽  
Thrombus Formation ◽  
The Other ◽  
Mean Survival Time ◽  
The Mean ◽  
And Function ◽  
Thrombotic Tendency

SummaryWe have investigated the relevance of some laboratory tests of platelet function in predicting conditions of thrombotic tendency. For this purpose, we studied platelet survival, platelet aggregation in response to different stimuli, TxB2 and 6-keto-PGFlα production in serum of rats bearing a nephrotic syndrome induced by adriamycin. These animals show a heavy predisposition to the development of both arterial and venous thrombosis. The mean survival time was normal in nephrotic rats in comparison to controls. As to aggregation tests, a lower aggregating response was found in ADR-treated rats using ADP or collagen as stimulating agents. With arachidonic acid (AA) we observed similar aggregating responses at lower A A concentrations, whereas at higher AA concentrations a significantly lower response was found in nephrotic rats, despite their higher TxB2 production. Also TxB2 and 6-keto-PGFlα levels in serum of nephrotic rats were significantly higher than in controls. No consistent differences were found in PGI2-activity generated by vessels of control or nephrotic rats.These data show that platelet function may appear normal or even impaired in rats with a markedly increased thrombotic tendency. On the other hand, the significance of high TxB2 levels in connection with mechanisms leading to thrombus formation remains a controversial issue.

Fidelity of J1269 and J24523

2007 ◽  
Vol 35 (2) ◽  
pp. 94-117 ◽  
Author(s):  
James A. Popio ◽  
John R. Luchini
Keyword(s):  
Steady State ◽  
Rolling Resistance ◽  
Test Methods ◽  
The Other ◽  
Reference Condition ◽  
Test Standards

Abstract This study compares data from the two Society of Automotive Engineers test methods for rolling resistance: J-2452 (Stepwise Coast-Down) and J-1269 (Equilibrium) steady state. The ability of the two methods to evaluate tires was examined by collecting data for 12 tires. The data were analyzed and the data showed that the two methods ranked the tires the same after the data were regressed and the rolling resistance magnitude was calculated at the Standard Reference Condition. In addition, analysis of the two methods using this matched set of testing provided an opportunity to evaluate each of these test standards against the other. It was observed that each test has merits absent from the other.

scholarly journals Lac Operon Boolean Models: Dynamical Robustness and Alternative Improvements

Mathematics ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 600 ◽  
Author(s):  
Marco Montalva-Medel ◽  
Thomas Ledger ◽  
Gonzalo A. Ruz ◽  
Eric Goles
Keyword(s):  
Escherichia Coli ◽  
Limit Cycles ◽  
The Other ◽  
Lac Operon ◽  
Boolean Models ◽  
Bistable Behavior

In Veliz-Cuba and Stigler 2011, Boolean models were proposed for the lac operon in Escherichia coli capable of reproducing the operon being OFF, ON and bistable for three (low, medium and high) and two (low and high) parameters, representing the concentration ranges of lactose and glucose, respectively. Of these 6 possible combinations of parameters, 5 produce results that match with the biological experiments of Ozbudak et al., 2004. In the remaining one, the models predict the operon being OFF while biological experiments show a bistable behavior. In this paper, we first explore the robustness of two such models in the sense of how much its attractors change against any deterministic update schedule. We prove mathematically that, in cases where there is no bistability, all the dynamics in both models lack limit cycles while, when bistability appears, one model presents 30% of its dynamics with limit cycles while the other only 23%. Secondly, we propose two alternative improvements consisting of biologically supported modifications; one in which both models match with Ozbudak et al., 2004 in all 6 combinations of parameters and, the other one, where we increase the number of parameters to 9, matching in all these cases with the biological experiments of Ozbudak et al., 2004.

scholarly journals Adult-onset sporadic chorea: real-world data from a single-centre retrospective study

2021 ◽  
Author(s):  
Roberta Bovenzi ◽  
Matteo Conti ◽  
Rocco Cerroni ◽  
Mariangela Pierantozzi ◽  
Alessandro Stefani ◽  
...  
Keyword(s):  
Clinical Examination ◽  
Real World ◽  
Laboratory Tests ◽  
Clinical Course ◽  
Diagnostic Workup ◽  
Adult Onset ◽  
Real World Data ◽  
Term Outcome ◽  
Long Term Outcome ◽  
World Data

Abstract Background Adult-onset sporadic chorea includes a wide and heterogeneous group of conditions whose differential diagnosis and treatments are often challenging and extensive. Objectives To analyse retrospectively cases of adult-onset sporadic chorea from a single Italian centre to provide insights for a practical approach in the management of these patients. Methods A total of 11,071 medical charts from a 9-year period (2012–2020) were reviewed, identifying 28 patients with adult-onset sporadic chorea (genetic forms excluded). All available data regarding phenomenology, diagnostic workup, aetiology, treatments, and long-term outcome from this cohort were collected and analysed. Results Adult-onset sporadic chorea occurred more frequently in females and presented with an acute-subacute onset. Cerebrovascular diseases accounted for 68% of aetiology; further causes were structural brain lesions, internal diseases, and other movement disorder syndromes. Clinical course was mild, with spontaneous resolution or minimal disturbances in 82% of cases. Neuroimaging was fundamental to diagnose 76% of adult-onset sporadic chorea, an appropriate clinical examination contributed to the 14% of diagnoses, whereas basic laboratory tests to the 10%. Conclusions Revision of real-world data of adult-onset sporadic chorea patients from a single Italian cohort suggests that an accurate clinical examination, neuroimaging, and routine laboratory tests are useful to identify those cases underlying potentially severe but treatable conditions. Although in the majority of cases adult-onset sporadic chorea has mild clinical course and good response to symptomatic treatments, it is essential to run a fast diagnostic workup.

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