Tonsillar leiomyoma

1987 ◽  
Vol 101 (6) ◽  
pp. 619-623 ◽  
Author(s):  
E. Greenberg ◽  
A. Shupak ◽  
Judith Kelner ◽  
W. S. Meyer
Keyword(s):  
Smooth Muscle ◽  
Spindle Cell ◽  
Correct Diagnosis ◽  
Surgical Excision ◽  
Mitotic Figure ◽  
First Case ◽  
Spindle Cell Tumours ◽  
Benign Leiomyoma ◽  
Histologic Types

AbstractTumors of smooth muscle origin are rare in the oral cavity. To date, only eighty-three cases of oral leiomyomas have been reported. A first case of tonsillar leiomyoma in a 73-year-old male is presented. The theories of origin and the various histologic types of oral leiomyomas are discussed. Leiomyoma can easily be confused with other spindle-cell tumours. Special stains are necessary to reach a correct diagnosis. It is sometimes difficult to differentiate benign leiomyoma from malignant leiomyosarcoma. The use of mitotic figure count to indicate malignant behaviour is not always reliable. The need for wide surgical excision of the tumour, complete sectioning and examination of the specimen and meticulous follow-up of the patient for evidence of recurrence are emphasized.

scholarly journals Acquired smooth muscle hamartoma: A case report on the lower extremity with hidrosis

2019 ◽  
Vol 7 ◽  
pp. 2050313X1989383
Author(s):  
Malika A Ladha ◽  
Todd Remington
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Lower Extremity ◽  
Smooth Muscle Cells ◽  
English Literature ◽  
Surgical Excision ◽  
Muscle Cells ◽  
Clinical Spectrum ◽  
Rare Entity ◽  
First Case

Smooth muscle hamartomas are benign dermal proliferations of smooth muscle cells. Smooth muscle hamartomas are sub-divided into congenital or acquired; the latter is a rare entity with less than 20 cases being reported in the English literature. Most often asymptomatic, acquired smooth muscle hamartomas follow an indolent course. Treatment in the form of surgical excision can be utilized for symptomatic or cosmetic purposes. Here, we report the first case of an acquired smooth muscle hamartomas of the shin which also uniquely presented with hidrosis. This case highlights the varied clinical spectrum of acquired smooth muscle hamartomas.

Piloleiomyosarcoma in Seven Ferrets

2001 ◽  
Vol 38 (6) ◽  
pp. 710-711 ◽  
Author(s):  
B. H. Rickman ◽  
L. E. Craig ◽  
M. H. Goldschmidt
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Immunohistochemical Staining ◽  
Smooth Muscle Actin ◽  
Surgical Excision ◽  
Muscle Actin ◽  
Mustela Putorius ◽  
Nuclear Pleomorphism ◽  
Complete Surgical Excision

In each of seven ferrets ( Mustela putorius furo) with leiomyosarcoma, a single dermal mass was identified and biopsied. Each mass consisted of a well-demarcated but nonencapsulated proliferation of large spindle- to strap-shaped cells arranged in interwoven bundles. The cells resembled the smooth muscle cells of the adjacent arrector pili muscles, but with marked nuclear pleomorphism. Immunohistochemical staining for smooth muscle actin, desmin, and vimentin was positive and staining for myoglobin and cytokeratin was negative. Follow-up on three of the ferrets indicates that the prognosis is good following complete surgical excision.

Leiomyosarcoma in a Posthysterectomy Patient

2017 ◽  
Vol 1 (1) ◽  
pp. 50-52
Author(s):  
Sujay Hegde ◽  
Naina Sawapure
Keyword(s):  
Smooth Muscle ◽  
De Novo ◽  
Laparoscopic Hysterectomy ◽  
Ovarian Neoplasm ◽  
Histopathological Analysis ◽  
Provisional Diagnosis ◽  
Benign Leiomyoma ◽  
Grade 3 ◽  
Infracolic Omentectomy

ABSTRACT Leiomyosarcoma is an aggressive soft tissue sarcoma derived from smooth muscle cells. Uterus is the commonest location for a leiomyosarcoma. They may either arise de novo from uterine musculature or the connective tissue of uterine blood vessels, or in a pre-existing benign leiomyoma and are associated with poor outcome. A 45 year patient presented with mass per abdomen. She had under gone laparoscopic hysterectomy three years back for menorrhagia. A provisional diagnosis of ovarian neoplasm was made based on the ultrasonography and CT scan report, but tumour markers were negative. Staging laparotomy was done, mass removed in toto, infracolic omentectomy, appendectomy and bilateral ureteric dissection was done. Post operatively, patient recovered well. Histopathological analysis was suggestive of leiomyosarcoma FNCLCC grade 3. Patient was advised radiation and is on regular follow up with the oncosurgeon. How to cite this article Agarwal M, Hegde S, Sawapure N. Leiomyosarcoma in a Posthysterectomy Patient. Int J Gynecol Endsc 2017;1(1):50-52.

scholarly journals An Unusual Presentation of Leiomyosarcoma Posing a Diagnostic Dilemma: A Case Report

2020 ◽  
Author(s):  
Smita Singh ◽  
Kusha Sharma ◽  
Vipan Kumar ◽  
Partap Yadav
Keyword(s):  
Smooth Muscle ◽  
Head And Neck ◽  
Histopathological Examination ◽  
Smooth Muscle Actin ◽  
Correct Diagnosis ◽  
Neck Region ◽  
Temporal Region ◽  
Diagnostic Dilemma ◽  
First Case ◽  
Painless Mass

Leiomyosarcoma (LMS) is a malignant tumour of smooth muscle origin commonly seen in genital and gastrointestinal location. However, its presence in the head and neck region in a young child is extremely rare. Authors present a unique case of LMS in a one year and five-month-old child who presented with a painless mass in the right temporal region of the head. Histopathological examination revealed a highly cellular tumour arranged in intersecting fascicles of spindle cells with brisk mitotic activity and interspersed areas of necrosis. On Immunohistochemistry (IHC), the tumour cells were positive for Smooth Muscle Actin (SMA), Desmin and Vimentin and negative for S100 and Myogenin. A diagnosis of LMS was thus, made. Head and neck sarcoma is a broad entity encompassing plethora of differentials with closely overlapping morphological features which renders them diagnostically challenging, this can be resolved by employing various immunohistochemical stains readily available in all laboratories. This case highlights the combined role played by histopathology and immunohistochemistry in arriving at the correct diagnosis. To the best of our knowledge, this is the first case of LMS reported in the temporal region of head and is distinct with respect to its rare incidence, location and age at presentation. LMS at this site may masquerade as deceptively benign painless mass and may not be suspected initially, however one should bear in mind that these are moderate-to-high grade tumours and any delay in management may portend poor prognosis. Timely and aggressive surgical management is thus, the mainstay of treatment and critical to patient survival.

scholarly journals Successful pregnancy after complete resection of leiomyomatosis peritonealis disseminate without recurrence: A case report with next generation sequencing analysis and literature review

2020 ◽  
Author(s):  
Hualei Bu ◽  
Chengjuan Jin ◽  
Yan Fang ◽  
Yana Ma ◽  
Xiao Wang ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Cesarean Section ◽  
Sequencing Analysis ◽  
Death Domain ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Tumors ◽  
Next Generation Sequencing Analysis ◽  
Benign Leiomyoma ◽  
High Level

Abstract Background: Peritoneal leiomyomatosis disseminate (LPD) is a rare disease characterized by widespread dissemination of leiomyomas nodules throughout the peritoneal and omental surfaces. Reports of pregnancy with LPD are even rarer. Therefore, there is no clear consensus on the treatment of LPD on pregnancy, and the pathogenesis is still unclear. Case presentation：We reported a case of LPD patient who developed during pregnancy. The patient underwent cesarean section at 32 weeks of gestation while removing all visible tumors, and no LPD lesions were seen in the subsequently cesarean section at full-term. NGS of LPD lesions detected 4 mutations with focal high-level amplifications of CDK4 (Cyclin-dependent kinases 4), NBN (Nibrin), DAXX (Death domain associated protein) and MYC (Myelocytomatosis oncogene). Immunohistochemistry staining analysis among benign leiomyoma, LPD and leiomyosarcoma verified that LPD was an unusual intermediate between benign and malignant uterine smooth muscle tumors. Besides, LPD is a hormonal-dependent leiomyoma. After detailed literature search, we summarized the detailed clinical features and follow-up information of patients with LPD during pregnancy. Conclusions: This is the first reported LPD case of successful term pregnancy without recurrence, following resection of all visible lesions in prior pregnancy. LPD is an unusual intermediate between benign and malignant uterine smooth muscle tumors.

scholarly journals Leiomyoma of the Cheek

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Ricardo Roberto de Souza Fonseca ◽  
Mário Augusto Ramos Junior ◽  
Douglas Baruchi ◽  
Tabata Resque Beckmann Carvalho ◽  
Andresa Borges Soares ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Gastrointestinal Tract ◽  
Smooth Muscle Cells ◽  
Rare Case ◽  
Surgical Excision ◽  
Muscle Cells ◽  
Benign Tumors ◽  
Tunica Media ◽  
The Right

Leiomyomas are rare benign tumors that grow in the tunica media of smooth muscle cells. Leiomyomas occur most frequently in the uterus or gastrointestinal tract and only very rarely in the area of the cheek. This study reports on a rare case of a leiomyoma in the cheek of a 43-year-old woman, who presented with a well-circumscribed, asymptomatic, mobile swelling in the right cheek. This swelling was slightly purplish in color and measured approximately 4 cm×3 cm. Surgical excision was the treatment of choice, and the diagnosis was based on histopathological and immunohistochemical stains, which were positive for actin and desmin and negative for AE1/AE3, CD34, and S100. The patient’s follow-up, two years later, showed no recurrence, and she has been asymptomatic since the surgery.

scholarly journals Pediatric Extraspinal Sacrococcygeal Ependymoma: Report of Two Cases and Literature Review

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1680
Author(s):  
Francesco Fabozzi ◽  
Silvia Ceccanti ◽  
Antonella Cacchione ◽  
Giovanna Stefania Colafati ◽  
Andrea Carai ◽  
...  
Keyword(s):  
Literature Review ◽  
Case Reports ◽  
Case Series ◽  
Surgical Excision ◽  
Central Canal ◽  
Ependymal Cells ◽  
The Past ◽  
First Case ◽  
One Year

Primary central nervous system (CNS) tumors represent the most common solid tumors in childhood. Ependymomas arise from ependymal cells lining the wall of ventricles or central canal of spinal cord and their occurrence outside the CNS is extremely rare, published in the literature as case reports or small case series. We present two cases of extra-CNS myxopapillary ependymomas treated at our institution in the past three years; both cases originate in the sacrococcygeal region and were initially misdiagnosed as epidermoid cyst and germ cell tumor, respectively. The first case, which arose in a 9-year-old girl, was treated with a surgical excision in two stages, due to the non-radical manner of the first operation; no recurrence was observed after two years of follow-up. The other case was a 12-year-old boy who was treated with a complete resection and showed no evidence of recurrence at one-year follow-up. In this paper, we report our experience in treating an extremely rare disease that lacks a standardized approach to diagnosis, treatment and follow-up; in addition, we perform a literature review of the past 35 years.

scholarly journals Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Álvaro Bengoa-González ◽  
Enrique Mencía-Gutiérrez ◽  
Beatriz Alonso-Martín ◽  
Bianca-Maria Laslău ◽  
Elena Salvador ◽  
...  
Keyword(s):  
Giant Cell ◽  
Surgical Excision ◽  
Clinicopathological Characteristics ◽  
Giant Cell Reparative Granuloma ◽  
First Case ◽  
Complete Surgical Excision ◽  
Cranial Fossa ◽  
Histopathologic Analysis ◽  
Fluid Levels

Giant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined mass, arising from the roof of the orbit, affecting the cortex, and invading the orbit. In the first case, the mass extended into the anterior cranial fossa. Magnetic resonance imaging with gadolinium showed, in both cases, a cystic character of the lesion with fluid levels. The surgical treatment was performed via an upper crease incision. An ultrasonic aspirator system was used to remove the tumor tissue and its extension into cranial fossa. Careful histopathologic analysis established the diagnosis of GCRG. Symptoms resolved completely with no evidence of recurrence after a follow-up of 18 and 14 months, respectively. We present the clinicopathological and radiological findings, and we describe the surgical approach. As a rare entity, GCRG of the orbit should be considered in differential diagnosis of fibroosseous orbital masses. Complete surgical excision carries a low risk of recurrence.

Gastric smooth muscle hamartoma in a cat

2010 ◽  
Vol 12 (4) ◽  
pp. 334-337 ◽  
Author(s):  
Thomas J. Smith ◽  
Wendy I. Baltzer ◽  
Craig G. Ruaux ◽  
Jerry R. Heidel ◽  
Patrick Carney
Keyword(s):  
Smooth Muscle ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Clinical Signs ◽  
Surgical Excision ◽  
Endoscopic Examination ◽  
Tissue Mass ◽  
Gastric Smooth Muscle ◽  
Esophageal Sphincter

An 11-year-old cat presented for evaluation of intermittent vomiting, constipation and hyporexia of 3 weeks duration. Ultrasonographic and endoscopic examination revealed a soft tissue mass adjacent to the lower gastro-esophageal sphincter. Surgical excision of the mass was successfully performed resulting in a resolution of clinical signs. Histologically the mass was consistent with a smooth muscle hamartoma. At follow-up 7 months after surgery, the cat remained free from clinical signs.

scholarly journals Uterine smooth muscle tumor of uncertain malignant potential: a case diagnosis, management and follow-up in the department of gynecology-obstetrics II of the Hassan II teaching hospital of Fes in Morocco

2020 ◽  
Vol 9 (6) ◽  
pp. 2598
Author(s):  
Alpha Boubacar Conte ◽  
Jihad Jamor ◽  
Fatima Zohra Fdili Alaoui ◽  
Sofia Jayi ◽  
Hikmat Chaara ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Tumor ◽  
Uterine Sarcoma ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Uterine Smooth Muscle ◽  
Histologic Types ◽  
Case Diagnosis ◽  
Muscle Tumor

Rarely diagnosed in authors department, uterine smooth muscle tumor of uncertain malignant potential (STUMP) is one of the histologic types of uterine sarcoma. Among women undergoing hysterectomy or myomectomy for a presumed diagnosis of leiomyoma, 0.01% receive a diagnosis of STUMP. Authors report a case occurring to a patient aged of 55 which was diagnosed, managed successfully and followed-up in authors department.

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