Analysis of the Factors Affecting Recurrence and Postoperative Incontinence after Surgical Treatment of Anal Fistula: A Retrospective Cohort Study

ObjectiveObstruction release from urolithiasis can be delayed with a lack of suggested time for preventing the deterioration of renal function. The objective of this study was to investigate the effect of obstruction duration, concomitant acute kidney injury (AKI) or acute pyelonephritis (APN) during the obstruction on the prognosis of renal function.DesignRetrospective cohort study.Setting and participants1607 patients from a urolithiasis-related obstructive uropathy cohort, between January 2005 and December 2015.Outcome measuresEstimated glomerular filtration rate (eGFR) decrease ≥30% and/or end-stage renal disease (ESRD), and eGFR decrease ≥50% and/or ESRD, according to obstruction duration, AKI and APN accompanied by obstructive uropathy.ResultsWhen the prognosis was divided by obstruction duration quartile, the longer the obstruction duration the higher the probability of eGFR reduction >50% (p=0.02). In patients with concomitant APN or severe AKI during hospitalisation with obstructive uropathy, an eGFR decrease of >30% and >50% occurred more frequently, compared with others (p<0.001). When we adjusted for sex, age, hypertension, diabetes mellitus, APN, AKI grades and obstruction release >7 days for multivariate analysis, we found that concomitant APN (HR 3.495, 95% CI 1.942 to 6.289, p<0.001), concomitant AKI (HR 3.284, 95% CI 1.354 to 7.965, p=0.009 for AKI stage II; HR 6.425, 95% CI 2.599 to 15.881, p<0.001 for AKI stage III) and an obstruction duration >7 days (HR 1.854, 95% CI 1.095 to 3.140, p=0.001) were independently associated with an eGFR decrease >50%. Tree analysis also showed that AKI grade 3, APN and an obstruction duration >7 days were the most important factors affecting renal outcome.ConclusionsIn patients with urolithiasis-related obstructive uropathy, concomitant APN was strongly associated with deterioration of renal function after obstruction release. The elapsed time to release the obstruction also affected renal function.

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Fistulectomy and primary sphincteroplasty (FIPS) to prevent keyhole deformity in simple anal fistula: a single-center retrospective cohort study

Acta Chirurgica Belgica ◽

10.1080/00015458.2020.1753151 ◽

2020 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Nicolas De Hous ◽

Thomas Van den Broeck ◽

Charles de Gheldere

Keyword(s):

Cohort Study ◽

Anal Fistula ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Single Center

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Surgical treatment and rehabilitation of medial Hoffa fracture fixed by locking plate and additional screws: A retrospective cohort study

International Journal of Surgery ◽

10.1016/j.ijsu.2015.05.027 ◽

2015 ◽

Vol 19 ◽

pp. 95-102 ◽

Cited By ~ 10

Author(s):

Mingjie Gao ◽

Jie Tao ◽

Zihui Zhou ◽

Qingbin Liu ◽

Lin Du ◽

...

Keyword(s):

Cohort Study ◽

Surgical Treatment ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Locking Plate ◽

Hoffa Fracture

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Effect of mammography screening on surgical treatment for breast cancer in Norway: comparative analysis of cancer registry data. A retrospective cohort study

BMJ ◽

10.1136/sbmj.e471 ◽

2012 ◽

pp. e471

Author(s):

Nick Dunn

Keyword(s):

Breast Cancer ◽

Cohort Study ◽

Comparative Analysis ◽

Surgical Treatment ◽

Cancer Registry ◽

Retrospective Cohort Study ◽

Mammography Screening ◽

Retrospective Cohort ◽

Registry Data ◽

Cancer Registry Data

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Does tonsillectomy reduce medical care visits for pharyngitis/tonsillitis in children and adults? Retrospective cohort study from Sweden

BMJ Open ◽

10.1136/bmjopen-2019-033817 ◽

2019 ◽

Vol 9 (11) ◽

pp. e033817 ◽

Cited By ~ 3

Author(s):

Eirik Østvoll ◽

Ola Sunnergren ◽

Joacim Stalfors

Keyword(s):

Cohort Study ◽

Surgical Treatment ◽

Medical Care ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Control Group ◽

Clinical Value ◽

Recurrent Tonsillitis ◽

Visit Rate ◽

The Difference

ObjectiveTo assess the effectiveness of tonsillectomy/adenotonsillectomy in reducing medical care visits for pharyngitis or tonsillitis in children and adults with chronic/recurrent tonsillitis.DesignRetrospective cohort study.SettingData were retrieved from the VEGA register, a comprehensive regional cohort in Sweden.Participants1044 children (<15 years) and 2244 adults.InterventionTonsillectomy/adenotonsillectomy compared with no surgical treatment.Main outcome measuresChanges in yearly mean rates of medical care visits due to pharyngitis/tonsillitis.ResultsIn children, there was a significant decrease in the yearly mean medical care visits rate from 1.93 (1.82 to 2.04) before surgery to 0.129 (0.099 to 0.165) after surgery, with a mean change of −1.80 (−1.90 to −1.69), p<0.0001. In patients who did not undergo surgery, the corresponding mean change was −1.51 (−1.61 to −1.41), resulting in a mean difference in the change in visit rates between the intervention and control groups of −0.283 (−0.436 to −0.135), p=0.0002. In adults, a significant decrease in the yearly mean medical care visit rate was observed from 1.45 (1.39 to 1.51) before surgery to 0.152 (0.132 to 0.173) after surgery, with a mean change of −1.30 (−1.36 to −1.24), p<0.0001, compared with −1.18 (−1.24 to −1.13) in the control group. The difference in the change in yearly mean visit rate between the surgical and non-surgical groups was −0.111 (−0.195 to −0.028), p=0.0097. The subgroup analysis showed a greater effect of surgery in children, in patients with a higher number of medical care visits before surgery and in the first year of follow-up.ConclusionIn this cohort of patients moderately or less affected with chronic/recurrent tonsillitis, the effectiveness of tonsillectomy/adenotonsillectomy in reducing medical care visits for pharyngitis and tonsillitis compared with no surgical treatment was low and of questionable clinical value.

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