Uterine Leiomyosarcoma Presenting as a Recurrent Abdominal Mass Following Total Abdominal Hysterectomy and Bilateral Salpingo-Oophorectomy: A Case Report

2008 ◽  
Vol 52 (2) ◽  
Author(s):  
M A Lamina ◽  
O A Oloyede ◽  
O T Oladapo
Keyword(s):  
Case Report ◽  
Abdominal Mass ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Uterine Leiomyosarcoma

scholarly journals A case report on an unusual degeneration of uterine leiomyoma: Myxoid degeneration

2018 ◽  
Vol 7 (4) ◽  
pp. 185-186
Author(s):  
Rupa Paneru ◽  
Meena Thapa
Keyword(s):  
Case Report ◽  
Uterine Leiomyoma ◽  
Abdominal Mass ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
The Body ◽  
Cystic Degeneration ◽  
Dystrophic Calcification ◽  
Cystic Area ◽  
Myxoid Degeneration

Background: Leiomyomas are benign smooth muscle neoplasm that typically occurs from the myometrium. Most of the women with uterine leiomyoma remain asymptomatic. Various degeneration including hyaline, cystic, myxoid and red degeneration and dystrophic calcification occur in leiomyoma, among them myxoid degeneration occurs rarely. Here is a case report of 40 years with one living child and two abortions who came with complaints of feeling of heaviness and pain at lower abdomen for six months, palpable lower abdominal mass for four months and difficulty in passing urine since 15 days. Multiple fibroids with cystic degeneration were suspected in Computed Tomography scan report. The patient underwent Total Abdominal Hysterectomy with Bilateral Salphingectomy. On cut section there was a cystic area on the body of uterus containing 1. 1 liter of straw coloured fluid. Final histopathological findings concluded multiple leiomyoma with myxoid degeneration.

Uterine-like Mass With Features of an Extrauterine Adenomyoma Presenting 22 Years After Total Abdominal Hysterectomy–Bilateral Salpingo-oophorectomy: A Case Report and Review of the Literature

2005 ◽  
Vol 129 (8) ◽  
pp. 1041-1043 ◽  
Author(s):  
Rachel Redman ◽  
Edward J. Wilkinson ◽  
Nicole A. Massoll
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Benign Tumor ◽  
Broad Ligament ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Hormonal Stimulation ◽  
Pelvic Organs

Abstract Adenomyoma is a benign tumor composed of smooth muscle and benign endometrium. These tumors typically originate within the uterus. An extrauterine adenomyoma is a rare entity. We report a uterine-like mass consistent with an extrauterine adenomyoma presenting 22 years following a total abdominal hysterectomy and bilateral salpingo-oophorectomy. The mass was pear-shaped with uterine-type smooth muscle and a cavity lined by functional endometrial glands and stroma. To our knowledge, only 4 other cases of an extrauterine uterine-like mass are reported in the literature. Three involved the ovary, while one was located adjacent to the broad ligament with normal pelvic organs. Although none of these other uterus-like masses were described as adenomyomas with uterine-like features, the histologic findings are strikingly similar. An understanding of the müllerian system suggests that either an embryologic malformation or a differential multipotentiality existing in the subcoelomic tissues in response to hormonal stimulation results in a supernumerary müllerian structure like a uterus, as observed in this case. The presence of endometrial glands and stroma in the mass confirms that the tissues in this mass are hormonally responsive. It is most likely that this uterine-like mass arose from the tissues of the secondary müllerian system in response to estrogenic stimulation.

scholarly journals The Imaging and Pathological Features of Metastatic Leiomyosarcoma in the Gallbladder

Rare Tumors ◽  
2016 ◽  
Vol 8 (4) ◽  
pp. 179-181 ◽  
Author(s):  
Yi Guo ◽  
Eleanor Chen ◽  
Darin J. Davidson ◽  
Venu G. Pillarisetty ◽  
Robin L. Jones ◽  
...  
Keyword(s):  
Metastatic Disease ◽  
Uterine Fibroids ◽  
Exploratory Laparotomy ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Metastatic Lesion ◽  
Uterine Leiomyosarcoma ◽  
High Grade ◽  
Initial Management ◽  
Pelvic Radiation

Uterine leiomyosarcoma is a rare and aggressive malignancy with poor overall prognosis. There have been few reports of metastatic leiomyosarcoma in the gallbladder. We report a case of a 41-year-old female who underwent total abdominal hysterectomy due to presumed uterine fibroids. The postoperative pathology revealed high-grade pleomorphic leiomyosarcoma, with involvement of the uterine serosal surface. She subsequently underwent exploratory laparotomy, followed by pelvic radiation and chemotherapy. Since initial management she has developed metastatic disease and has been under treatment and surveillance for 11 years. She has undergone multiple surgical procedures and numerous lines of systemic therapy for metastatic leiomyosarcoma, including cholecystectomy for a metastatic lesion in the gallbladder. There have been no previous reports of metastatic leiomyosarcoma in the gallbladder. Despite extensive metastatic disease this patient has had prolonged survival with multi-modality management.

Cervical Ectopic Pregnancy: Case Report

1970 ◽  
Vol 25 (2) ◽  
pp. 92-94
Author(s):  
Laila Parveen Banu ◽  
Sameena Chowdhury ◽  
Kohinoor Begum ◽  
Ferdousi Islam ◽  
Saria Tasnim
Keyword(s):  
Case Report ◽  
Ectopic Pregnancy ◽  
Vaginal Bleeding ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Naked Eye ◽  
Life Threatening ◽  
Eye Examination ◽  
Cervical Ectopic Pregnancy

A thirty year old lady para 3+0 presented with complaints of amenorrhoea for eight weeks and slight per vaginal bleeding for 28 days with frequent bouts of profuse bleeding. Total abdominal hysterectomy was done. Naked eye examination of the specimen was suggestive of cervical ectopic pregnancy (CEP). Histopathology report confirmed cervical implantation of placenta. CEP is an extremely rare life threatening form of ectopic pregnancy. (J Bangladesh Coll Phys Surg 2007; 25 : 92-94)

Cure of metastatic uterine carcinosarcoma to lungs: A case report

2003 ◽  
Vol 13 (1) ◽  
pp. 88-89
Author(s):  
A. Shamseddine ◽  
A. Taher ◽  
Y. Abou-Mourad ◽  
M. Seoud ◽  
A. Khalil
Keyword(s):  
Case Report ◽  
Systemic Chemotherapy ◽  
Pulmonary Nodules ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Uterine Sarcoma ◽  
Uterine Carcinosarcoma ◽  
Pelvic Radiotherapy ◽  
Term Survival

Most patients with advanced or recurrent uterine sarcoma experience disease progression and ultimately die. We present a case of uterine sarcoma with lung metastasis treated with systemic chemotherapy and with no evidence of disease for more than 5 years. A 77-year-old woman underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy for carcinosarcoma of the uterus followed by external pelvic radiotherapy. Ten months later, the tumor recurred in the apex of the vagina and was treated with brachytherapy. After 6 months of remission, she presented with pulmonary metastasis. After four cycles of systemic chemotherapy with cisplatin and ifosfamide, the pulmonary nodules completely disappeared. Currently she is still in complete remission after more than 5 years, but unfortunately she has developed myelodysplastic syndrome. This is the first reported case in the literature of cured metastatic uterine carcinosarcoma to lungs, with long-term survival of 5 years.

Mucoepidermoid variant of adenosquamous carcinoma arising in ovarian dermoid cyst: a case report and review of the literature

2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 379-384
Author(s):  
A. Karateke ◽  
A. Gurbuz ◽  
G. Kir ◽  
B. Haliloglu ◽  
C. Kabaca ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Dermoid Cyst ◽  
Adenosquamous Carcinoma ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Review Of The Literature ◽  
Lymph Node Sampling ◽  
Aortic Lymph Node ◽  
Ovarian Dermoid Cyst

A 40-year-old woman with mucoepidermoid variant of adenosquamous carcinoma arising in dermoid cyst in left ovary is presented. The patient was staged as IC. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and pelvic and para-aortic lymph node sampling were carried out. The disease recurred in postoperative 12th month. To our best knowledge, this is 12th case of adenosquamous carcinoma in dermoid cyst and third case of mucoepidermoid variant of adenosquamous carcinoma in the literature.

scholarly journals Uterine Myoma: A Profile of Nepalese women

1970 ◽  
Vol 1 (2) ◽  
pp. 47-50
Author(s):  
Pramila Pradhan ◽  
Nitish Acharya ◽  
Binit Kharel ◽  
Manoj Manjin
Keyword(s):  
Abdominal Mass ◽  
College Teaching ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Early Marriage ◽  
Early Completion ◽  
Medical College ◽  
Underlying Risk Factor ◽  
The Mean ◽  
Myoma Uteri

Objectives: To determine the most common age and parity for the development of myoma uteri. To find out any relation between age of the last child and the development of myoma uteri. To determine the treatment protocal and outcome of treatment. Materials/methods: This study was carried out at Nepal Medical College Teaching Hospital from Jan 2001 to 31st June 2006. All cases of myoma uteri admitted in Gynaecological ward was included.. Histological evidence of myoma confirmed the diagnosis. Age, parity and age of the last child, clinical features, surgical procedures and outcome of surgery were considered. Results: A total of 137 cases of myoma uteri was operated during five and half years period. This represented 38.5 %of all abdominal hysterectomy performed during the same period. The mean age was 43.3 years with median parity at 1-3 and the mean age of last child at 12years. Excessive menstrual bleeding 73.0%, abdominal mass and pain 58.4%, dysmenorrhea 18.2% and infertility 7.3% were the common symptoms. Total abdominal hysterectomy was the mainstay of treatment. Patients were happy with the treatment specially those with severe and multiple symptoms Postoperative complications were not significant. There was one death due to pulmonary embolism who had mesothelioma of pleura diagnosed by pleural biopsy before operation. Conclusion: Early marriage and early completion of the family is the social trend in Nepalese society. Myoma is common in 4th-5th decade of life in multi parity with the age of last child around 12years. This long standing secondary infertility may be an underlying risk factor in the development of myoma uteri.   doi:10.3126/njog.v1i2.2397 N. J. Obstet. Gynaecol Vol. 1, No. 2, p. 47-50 Nov-Dec 2006   

scholarly journals Management Strategies in Advanced Uterine Leiomyosarcoma: Focus on Trabectedin

Sarcoma ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Frédéric Amant ◽  
Domenica Lorusso ◽  
Alexander Mustea ◽  
Florence Duffaud ◽  
Patricia Pautier
Keyword(s):  
Therapeutic Potential ◽  
Management Strategies ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Local Tumor Control ◽  
Tumor Control ◽  
Uterine Leiomyosarcoma ◽  
Chemotherapy Drugs ◽  
Risk Patients ◽  
Overall Survival Benefit

The treatment of advanced uterine leiomyosarcomas (U-LMS) represents a considerable challenge. Radiological diagnosis prior to hysterectomy is difficult, with the diagnosis frequently made postoperatively. Whilst a total abdominal hysterectomy is the cornerstone of management of early disease, the role of routine adjuvant pelvic radiotherapy and adjuvant chemotherapy is less clear, since they may improve local tumor control in high risk patients but are not associated with an overall survival benefit. For recurrent or disseminated U-LMS, cytotoxic chemotherapy remains the mainstay of treatment. There have been few active chemotherapy drugs approved for advanced disease, although newer drugs such as trabectedin with its pleiotropic mechanism of actions represent an important addition to the standard front-line systemic therapy with doxorubicin and ifosfamide. In this review, we outline the therapeutic potential and in particular the emerging evidence-based strategy of therapy with trabectedin in patients with advanced U-LMS.

scholarly journals Ovarian dysgerminoma: a case report

2021 ◽  
Vol 10 (4) ◽  
pp. 1704
Author(s):  
Shamrao Ramji Wakode ◽  
Varsha Narayana Bhat
Keyword(s):  
Young Women ◽  
Ovarian Neoplasms ◽  
Abdominal Mass ◽  
Total Abdominal Hysterectomy ◽  
Malignant Tumour ◽  
Abdominal Hysterectomy ◽  
Tumour Mass ◽  
Mesenteric Lymph ◽  
Beta Hcg ◽  
Ovarian Dysgerminoma

An ovarian dysgerminoma is a rare, malignant tumour occurring in young women, accounting for 1% to 2% of all primary ovarian neoplasms. A 22 years old female presented with 6 months of amenorrhea and lump in the abdomen. Her physical examination was remarkable with 36 weeks sized huge abdominal mass. Subsequent computed tomography revealed 22×23×32.4 cm mixed density lesion in pelvi-abdominal region and multiple paraaortic and mesenteric lymph node with gross pleural effusion. On further evaluation raised beta-hcG and LDH were noted and hence dysgerminoma was suspected. Total abdominal hysterectomy with right salpingo-ophorectomy with resection of tumour mass with partial omentectomy and lymphadenectomy was performed. Histopathology reports were suggestive of dysgerminoma. 

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