Nocturnal enuresis among children in Morogoro region in Tanzania: A cross-sectional survey

2020 ◽  
Vol 31 (1) ◽  
pp. 16-29
Author(s):  
Nehemia Kilongo ◽  
Francis F. Furia
Keyword(s):  
Family History ◽  
Demographic Data ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
African Region ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Childhood Disorders ◽  
Factors Affecting ◽  
History Of

Background: Enuresis is common childhood disorders which affecting quality of life of children and causing significant psychosocial disturbances to children and their families. This condition has been widely reported globally with increasing data from sub-Saharan African region. In Tanzania there is no reports on its magnitude and therefore this study was carried out with the aim of determine the prevalence of this condition among children in Tanzania.Methods: This was a community based cross-sectional study conducted among children aged between 5 and 14 years recruited from 12 streets in Morogoro Municipality in Tanzania. Standardized Swahili questionnaire was used to collect data including socio-demographic details of parents,  children and presence of enuresis. Socio-demographic data included age of the child, sex, level of education of the parents, education of the child, presence of bed wetting, history of enuresis in the family.Results: Five hundred and ten children were recruited into this study out of which 271 (53.1%) were females and mean age of study participants was 9±2.8 years. Enuresis was noted in 19% (97/510) of children, 68% (66/97) and 32% (31/97) had primary and secondary enuresis respectively. Significantly higher prevalence rates of enuresis were noted for children aged below 8 years 26.4% (43/162) and those with family history of enuresis 47% (18/38) with p values of 0.01 and < 0.001 respectively. Forty-one (42.3%) out of 97 respondents whose children had enuresis reported to have punished their children and only 21.4% (20/97) reported to have sought treatment for their children.Conclusions: Enuresis is common among children in Tanzania particularly those with positive family history. Punishment to children with enuresis was noted in this study and only one in five parents/guardians sought treatment for their affected children. Therefore, there is a need for initiatives for raising community awareness about enuresis in Tanzania Key words: Enuresis in children, prevalence of enuresis in Tanzania, factors affecting enuresis in children.

scholarly journals Differential expression of micro RNA-29 family in non-diabetic adults of diabetic and non-diabetic parents

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Uzair Abbas ◽  
Bushra Imdad ◽  
Sikander Adil Mughal ◽  
Israr Ahmed Baloch ◽  
Afshan Mehboob Khan ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Family History ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Vital Role ◽  
Micro Rna ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Abstract Objective MicroRNAs are known to regulate 60% of genes at post translational level. MicroRNAs including Micro RNA-29 family play a vital role in cellular activities and have validate role in numerous metabolic disorders inclusive of diabetes mellitus and its complications. While micro RNA profile changes years before the occurrence of disease. This cross-sectional study was conducted in non-diabetic adults of diabetic and non-diabetic parents to explore the early changes in expression of micro RNA-29 family as it can be served as early biomarker of type 2 diabetes in non-diabetic adults. This study was conducted from January 2019 to January 2021. Micro RNA was extracted from plasma of 50 participants and expression was compared through qPCR. While data was analyzed through SPSS version 21.0. Results 29a and 29b had lower expression in participants with family history of DM compared to those having no family history of DM (P < 0.0001). While micro RNA 29c was found to be significantly higher in participants with positive family history of type 2 diabetes as compared to those without family history of diabetes (P = 0.001).

What is known about Prostate Cancer? Response from Men Aged 50 Years and Above in Lindi Municipal, Tanzania

2020 ◽  
Vol 31 (2) ◽  
pp. 33-44
Author(s):  
Simon Francis ◽  
Obadia V. Nyongole
Keyword(s):  
Prostate Cancer ◽  
Family History ◽  
Positive Family History ◽  
Negative Attitude ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Adult Men ◽  
History Of ◽  
One Year ◽  
High Level

Background: The incidence of prostate cancer in Tanzania is among the highest recorded in Africa. Prostate cancer is also the most common cancer among men aged 50 years and above in Tanzania. Our study aimed to determine the awareness, knowledge, and attitudes among adult men with age 50 years and above regarding prostate cancer.Methods: This was a cross-sectional study that included 250 adult men aged 50 years and above in Lindi municipal being purposively selected and we interviewed them by using a structured questionnaire. A stratified random sampling method was used for obtaining our participants. All men who had stayed for not less than one year in Lindi and willing to participate were enrolled in the study. These men were selected at households without screening whether or not they had taken prostate screening test or had been diagnosed with prostate cancer Quantitative data were cleaned and analyzed with SPSS version 20.Results: Majority, 216(86.7%) of our study participants were aged 50–69 years and most of them, 142(56.8%) had primary education with 93.2% of them being married. Among the study subjects 7.2% had positive family history of cancer and 195(78%) were aware of prostate cancer with source of information being mass media (62.6%). Majority of them, 63.2%, did not know the risk age group. Few, 20.8% of our participants had good knowledge while majority, 95.2% had negative attitude toward prostate cancer. We found a statistically significant association between level of education, family history and level of knowledge regarding prostate cancer with p < 0.005.Conclusion: This study revealed high level of awareness, but poor knowledge regarding prostate cancer and negative attitude toward prostate cancer among men with age ≥50 years in Lindi municipal Tanzania. Key words: Awareness, knowledge, attitude, prostate cancer.

scholarly journals Cataract and its risk factor among adults residing in South Bihar, India

2020 ◽  
Vol 8 (7) ◽  
pp. 2618
Author(s):  
Shiwani Gupta ◽  
Animesh Gupta ◽  
M. Nehal ◽  
Kalyani Pandey ◽  
Ananta Kreesna ◽  
...  
Keyword(s):  
Family History ◽  
Urban Areas ◽  
Dietary Habits ◽  
Demographic Data ◽  
Sun Exposure ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Age Related ◽  
History Of

Background: Cataract is considered as one of the most common causes of visual impairment and the leading cause of blindness in the world. Age related cataract occurs in people above 50 years of age and the its pathogenesis is multifactorial. Therefore, the present study was aimed to assess the prevalence and risk factors for cataract.Methods: Community based cross sectional study was conducted among adults residing at urban areas of South Bihar. The data was collected by interview method, using pre-tested semi-structured questionnaire which contains socio-demographic data, dietary habits, history of diabetes or hypertension, family history of cataract and long-term sun exposure.Results: Among 240 participants, 94 (39.2%) were male and 146 (60.8%) were female. Maximum participants were aged more than 70 years. The prevalence of cataract was 52.1%.Conclusions: The prevalence of cataract was quite high and was significantly associated with age, long term sun exposure and family history of cataract.

scholarly journals Practice of Eye Checks among Medical Doctors in South-East Nigeria

2021 ◽  
pp. 38-46
Author(s):  
Arinze Anthony Onwuegbuna ◽  
Akunne Ijeoma Apakama ◽  
Miriam-Benigna Chika Amobi ◽  
Emeka Akujuobi Chianakwalam ◽  
Chuka Michael Okosa ◽  
...  
Keyword(s):  
Family History ◽  
Visual Impairment ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Eye Diseases ◽  
Public Hospitals ◽  
Medical Doctors ◽  
Cross Sectional ◽  
Factors Affecting ◽  
History Of

Visual impairment greatly affects one’s quality of life. The number of persons with visual impairment and blindness in the world is on the increase. Eye screening allows for early detection of sight-threatening diseases and timely intervention could be sight-saving.  Aim: To determine the practice of eye checks and identify the factors that affect periodic eye checks among medical doctors in south-east Nigeria. Methodology: This study was a descriptive, cross-sectional study conducted among practicing medical doctors in private and public hospitals in Anambra State Nigeria, using a self-administered semi-structured questionnaire. Information obtained from the participants included the sociodemographics data, type and duration of practice, presence of any medical and/or ocular condition, family history of eye diseases, history of use of spectacles, practice of eye check and interval of eye check, factors affecting the practice of eye check, and ways of promoting regular eye check. Data obtained were analysed using the Statistical Package for the Social Sciences version 23. Statistical significance was set at p˂0.05.  Results: One hundred and eighty-seven practicing  medical doctors were interviewed. There were 123 (65.8%) males and 64 (34.2%) females. Their ages ranged from 24 to 80 years, with a mean age of 44.81 ± 12.73 years. The mean duration of professional practice was 18.16 ± 11.9 years. Majority, 124 (66.3%) works in government-owned hospitals. Among the study participants, 93(49.7%) doctors had been diagnosed with different ocular diseases; 99(52.9%) had a family history of ocular problems; 94(50.3%) had used prescription lenses; and 51(27.3%) had medical conditions. One hundred and twelve (59.9%) had undergone at least  eye examinations once, of which 54(48.2%) had their last eye examination over 5 years ago. The prevalence of eye check was 59.9% (95%CI: 52.9 – 66.9%). Eye checks were significantly associated with medical practice of over 20 years (P=0.030), working in a private practice (P=0.001), having eye diseases such as cataract (P=0.006), refractive error (P˂0.001), presbyopia (P˂0.001), and use of prescription spectacles (P˂0.001). ‘Belief of not having eye problems’ and ‘No time’ which accounted for 58.7% and 24.0% respectively were the commonest reasons for not regularly  having eye examinations.  Conclusion: Poor attitude to periodic eye examinations was seen in medical doctors in south east Nigeria. 

Prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas

Gut ◽  
2019 ◽  
Vol 69 (2) ◽  
pp. 304-310 ◽  
Author(s):  
Siew C Ng ◽  
Moe Htet Kyaw ◽  
Bing Yee Suen ◽  
Yee Kit Tse ◽  
Martin C S Wong ◽  
...  
Keyword(s):  
Family History ◽  
Colorectal Neoplasms ◽  
Colorectal Neoplasia ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Advanced Adenoma ◽  
Degree Relative ◽  
Cross Sectional ◽  
History Of ◽  
Advanced Adenomas

ObjectiveThe risk associated with a family history of non-advanced adenoma (non-AA) is unknown. We determined the prevalence of colorectal neoplasms in subjects who have a first-degree relative (FDR) with non-AA compared with subjects who do not have an FDR with adenomas.DesignIn a blinded, cross-sectional study, consecutive subjects with newly diagnosed non-AA were identified from our colonoscopy database. 414 FDRs of subjects with non-AA (known as exposed FDRs; mean age 55.0±8.1 years) and 414 age and sex-matched FDRs of subjects with normal findings from colonoscopy (known as unexposed FDRs; mean age 55.2±7.8 years) underwent a colonoscopy from November 2015 to June 2018. One FDR per family was recruited. FDRs with a family history of colorectal cancer were excluded. The primary outcome was prevalence of advanced adenoma (AA). Secondary outcomes included prevalence of all adenomas and cancer.ResultsThe prevalence of AA was 3.9% in exposed FDRs and 2.4% in unexposed FDRs (matched OR (mOR)=1.67; 95% CI 0.72 to 3.91; p=0.238 adjusted for proband sex and proband age). Exposed FDRs had a higher prevalence of any adenomas (29.2% vs 18.6%; mOR=1.87; 95% CI 1.32 to 2.66; p<0.001) and non-AA (25.4% vs 16.2%; mOR=1.91; 95% CI 1.32 to 2.76; p=0.001). A higher proportion of exposed FDRs than unexposed FDRs (4.3% vs 2.2%; adjusted mOR=2.44; 95% CI 1.01 to 5.86; p=0.047) had multiple adenomas. No cancer was detected in both groups.ConclusionA positive family history of non-AA does not significantly increase the risk of clinically important colorectal neoplasia. The data support current guidelines which do not advocate earlier screening in individuals with a family history of non-AA.Trial registration numberNCT0252172.

MO855PREVALENCE OF SELF-REPORTED KIDNEY  DISEASE AMONG THE FIRST DEGREE RELATIVES OF SAUDI PATIENTS ON DIALYSIS AND ITS RELATIONSHIP TO SPECULATIVE VERSUS DEFINITIVE CAUSES OF CKD IN THE INDEX CASE

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Abdulla Al-Sayyari
Keyword(s):  
Family History ◽  
Kidney Disease ◽  
Positive Family History ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Diagnostic Labels ◽  
Diagnostic Certainty ◽  
Dialysis Vintage ◽  
History Of ◽  
Male Patients

Abstract Background and Aims CKD is common in Saudi Arabia. This study evaluates and compares the prevalence and clinical characteristics of Saudi dialysis patients with a positive family history of kidney disease to those without such a history and to assess certainty of the CKD diagnosis by their physicians. Method This is a cross-sectional survey-based study on adult Saudi hemodialysis patients in six dialysis centers in four Saudi cities. The first part of the survey recorded the demographic variables and the degree of diagnostic certainty (completed by the physicians) and the second part (completed by the patients) recorded first degree family history of kidney disease. Results A total of 1080 patients were included. The prevalence of positive family history (FH) was 21.5%. The number of relatives affected was 285, (41%) were parents and (57%) were siblings. More relatives of female patients had ESRD than in relatives of male patients (80.2% and 68.9% respectively) (p=0.0001). There were significantly more patients with “unknown” or “hypertensive” diagnostic labels among the patients with FH of kidney disease than in the group without a family history (p=007 and 0.005 respectively). Dialysis vintage was significantly shorter and CKD vintage was significantly longer in positive FH patients (4.9 ±6.4 yrs.) than in patients without FH (5.9 ±5.8yrs) (p=0.03). The duration since the diagnosis of CKD was made was significantly longer in patients with FH of kidney disease (7.5±7.7 yrs.) than in patients without (2.0±4.5) (p=0.0001). Of all the diagnoses given to the patients, more than half (57.8%) were either “unknown” (33%) or only speculative in nature (25.3%). In those with a diagnostic label, the diagnosis was thought to be definitive in only 62.2% of the cases. Conclusion The prevalence of FH of kidney disease was 21.5%, and it was more prevalent with patients with “unknown” or “hypertension” (13%) diagnostic labels.

scholarly journals Factors Affecting Irritable Bowel Syndrome in Medical Students

2020 ◽  
Vol 21 (2) ◽  
pp. 95-98
Author(s):  
Ellen Fernanda ◽  
Andree Kurniawan
Keyword(s):  
Irritable Bowel Syndrome ◽  
Medical Students ◽  
Family History ◽  
Demographic Data ◽  
Drug Consumption ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Factors Affecting ◽  
History Of ◽  
Irritable Bowel

Background: Irritable Bowel Syndrome (IBS) is one of the health problems that bring great effects in education, productivity, and socioeconomic life in Indonesia. It accounts for approximately 10.5% of 304 digestive problems in Jakarta, Indonesia. Particular characteristics are known to increase the risk of IBS in individuals, but the study of IBS in Indonesia is still limited in number. The objective of this study is to assess the prevalence and factors affecting Irritable Bowel Syndrome in medical students.Method: This study is a cross sectional study on medical students of Pelita Harapan University, Karawaci, Tangerang on January 2018 until March 2018. Data were obtained with the use of questionnaire of demographic data, ROME IV IBS Criteria, GAD DSM-IV, and PSQI as the instruments with random sampling technique, and statistically tested using Chi-Squared test.Results: A total of 210 samples consist of 54 subjects with IBS (25.7%) with 43 women (79.6%) and 11 men (20.4%). Findings of bivariate analysis are sex (95% CI, 0.751 - 3.346), obesity (95% CI, 0.612 - 2.673), history of drug consumption (95% CI, 1.246 - 6.742), family history of IBS (95% CI, 1.246 - 6.742), anxiety (95% CI, 1.419 - 9.709), and sleep disorder (95% CI, 0.514 - 1.785).Conclusion: The prevalence of IBS in medical students in our institution is 25.7% with history of drug consumption, family history of IBS, and anxiety as factors statistically significant in IBS.

scholarly journals Obstructive Sleep Apnea and Associated Factors Among Hypertensive Patients Attending a Tertiary Cardiac Center in Tanzania: a Comparative Cross-sectional Study

2021 ◽  
Author(s):  
Pedro Pallangyo ◽  
Lucy R. Mgopa ◽  
Zabella Mkojera ◽  
Makrina Komba ◽  
Jalack Millinga ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Family History ◽  
Nasal Congestion ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Excess Body Weight ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
History Of

Abstract Background: There is mounting evidence for a reciprocal yet bidirectional association between sleep-disordered breathing and hypertension. Obstructive sleep apnea (OSA), a common cause of systemic hypertension is an independent risk factor for hypertension-related cardiovascular morbidity and mortality. In this comparative hospital-based cross-sectional study, we sought to explore the burden of obstructive sleep apnea and its associated risk factors among hypertensive patients attending Jakaya Kikwete Cardiac Institute.Methodology: A total of 1974 individuals (i.e. 1289 hypertensive and 685 normotensives) were consecutively enrolled in this study. The Berlin questionnaire and Epworth Sleepiness Scale were utilized in the assessment of OSA and excessive daytime sleepiness (EDS) respectively. Logistic regression analyses were employed in the determination of associated factors for OSA. Results: The mean age was 53.4 years and females constituted the large majority (60.4%) of participants. About three quarters (74.1%) of participants had excess body weight, 11.6% had diabetes, 8.0% had asthma and 18.6% had history of recurrent nasal congestion. Positive family history of snoring was reported by 43.1% of participants and 36.9% had a personal history of snoring. Persons with hypertension displayed a higher frequency (42.1%) of OSA compared to their normotensive counterparts (11.8%), p<0.001. Multivariate logistic regression analyses revealed hypertension (OR 5.1, 95% CI 3.2-8.2, p<0.001), diabetes mellitus (OR 2.2, 95% CI 1.3-3.5, p<0.01), chronic nasal congestion (OR 1.6, 95% CI 1.1-2.5, p = 0.01), obesity (OR 2.4, 95% CI 1.8-3.3, p<0.001), increased neck circumference (OR 2.7, 95% CI 1.2-6.4, p = 0.02), family history of snoring (OR 5.5, 95% CI 4.0-7.5, p<0.001), and working >8hrs/24hr (OR 0.6, 95% CI 0.4-1.0, p = 0.03) to have an independent association for OSA. Furthermore, participants with hypertension displayed superior odds for OSA compared to their normotensive counterparts across all subgroup analyses. Conclusion: OSA is considerably common among hypertensives in a tertiary health care setting in Tanzania. Positive family history of snoring was the strongest associated factor; however, excess body weight proved to be the strongest modifiable risk factor. In view of its pervasiveness, OSA should be an integral part of the medical evaluation in hypertensive individuals.

scholarly journals Relationship Between Concomitant Atopic Diseases With Atopic Dermatitis Severity And Persistence.

2021 ◽  
Vol 6 (2) ◽  
pp. 43-47
Author(s):  
Adawiyah Jamil ◽  
Siew Wen Goh ◽  
Chon Sian Lee ◽  
Mohan Arumugam
Keyword(s):  
Atopic Dermatitis ◽  
Family History ◽  
Demographic Data ◽  
Atopic Disease ◽  
Cross Sectional Study ◽  
Atopic Diseases ◽  
Cross Sectional ◽  
Face To Face ◽  
Tertiary Hospitals ◽  
History Of

Introduction: The atopic march consists of atopic dermatitis (AD), allergic rhinitis or sinusitis (AR), allergic conjunctivitis (AC) and bronchial asthma (BA). The influence of concomitant atopic diseases on AD is under-explored. We determined the relationship between personal and family history of atopic diseases with AD severity and persistence. Methods: A cross sectional study involving AD patients was performed at dermatology clinics of two tertiary hospitals. Inclusion criterion was all patients diagnosed with AD. Demographic data, personal and family history of atopy (BA, AR and AC) were obtained by face-to-face interview. AD severity was evaluated using Investigator’s Global Assessment (IGA). AD was considered persistent if continued beyond age 12 years. Results: Sixty patients aged 21.6±17.2 participated. There were 25(41.7%) with concomitant AR, 16(26.7%) BA and 12(20%) AC. Forty seven (78.3%) patients had family history of atopy, 25(41.7%) had eczema, 24(40%) AR, 19(31.7%) BA and 2(3.3%) AC. Patients with BA [OR=3.8, 95%CI 1.04 to 14.4)], BA and AR [OR=9.74, 95%CI 1.13 to 83.67) and family history of BA [OR= 4.00, 95%CI 1.20 to 13.27) were more likely to exhibit moderate-severe AD. Personal AR, AC and family history of AD and BA were significantly more prevalent in patients with persistent AD. Conclusions: AR was the most common atopic disease associated with AD. Family history of eczema and AR were common. Personal BA, BA with AR and family history of BA were predictors of severe AD. Personal AR, AC and family history of AD and BA were associated with AD persistence.

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