A Technology-Focused Sharing Space for Faculty

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to an organism and still perform crosstalk, acting through the endocrine, paracrine, and autocrine pathways. This study aims to review the crosstalk between adipokines, myokines, and hepatokines. Far beyond understanding the actions of each biomarker alone, it is important to underline that these cytokines act together in the body, resulting in a complex network of actions in different tissues, which may have beneficial or non-beneficial effects on the genesis of various physiological disorders and their respective outcomes, such as type 2 diabetes mellitus (DM2), obesity, metabolic syndrome, and cardiovascular diseases (CVD). Overweight individuals secrete more pro-inflammatory adipokines than those of a healthy weight, leading to an impaired immune response and greater susceptibility to inflammatory and infectious diseases. Myostatin is elevated in pro-inflammatory environments, sharing space with pro-inflammatory organokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), resistin, and chemerin. Fibroblast growth factor FGF21 acts as a beta-oxidation regulator and decreases lipogenesis in the liver. The crosstalk mentioned above can interfere with homeostatic disorders and can play a role as a potential therapeutic target that can assist in the methods of diagnosing metabolic syndrome and CVD.

Download Full-text

Interpersonal Communication: Taking, Giving, and Sharing Space

The International Manager ◽

10.1201/b18454-4 ◽

2015 ◽

pp. 22-47

Keyword(s):

Interpersonal Communication ◽

Sharing Space

Download Full-text

What do patients experience? Interprofessional collaborative practice for chronic conditions in primary care: an integrative review

BMC Primary Care ◽

10.1186/s12875-021-01595-6 ◽

2022 ◽

Vol 23 (1) ◽

Author(s):

Alexandra R. Davidson ◽

Jaimon Kelly ◽

Lauren Ball ◽

Mark Morgan ◽

Dianne P. Reidlinger

Keyword(s):

Primary Care ◽

Chronic Conditions ◽

Chronic Condition ◽

Collaborative Practice ◽

Integrative Review ◽

Patient Role ◽

Interprofessional Collaborative Practice ◽

Sharing Space ◽

Patients Experience

Abstract Background Improving the patient experience is one of the quadruple aims of healthcare. Therefore, understanding patient experiences and perceptions of healthcare interactions is paramount to quality improvement. This integrative review aimed to explore how patients with chronic conditions experience Interprofessional Collaborative Practice in primary care. Methods An integrative review was conducted to comprehensively synthesize primary studies that used qualitative, quantitative, and mixed methods. Databases searched were Medline, Embase, CINAHL and Web of Science on June 1st, 2021. Eligible studies were empirical full-text studies in primary care that reported experiences or perceptions of Interprofessional Collaborative Practice by adult patients with a chronic condition, in any language published in any year. Quality appraisal was conducted on included studies using the Mixed Method Appraisal Tool. Data on patients’ experiences and perceptions of Interprofessional Collaborative Practice in primary care were extracted, and findings were thematically analyzed through a meta-synthesis. Results Forty-eight (n = 48) studies met the inclusion criteria with a total of n = 3803 participants. Study quality of individual studies was limited by study design, incomplete reporting, and the potential for positive publication bias. Three themes and their sub-themes were developed inductively: (1) Interacting with Healthcare Teams, subthemes: widening the network, connecting with professionals, looking beyond the condition, and overcoming chronic condition collectively; (2) Valuing Convenient Healthcare, subthemes: sharing space and time, care planning creates structure, coordinating care, valuing the general practitioner role, and affording healthcare; (3) Engaging Self-care, subthemes: engaging passively is circumstantial, and, engaging actively and leading care. Conclusions Patients overwhelmingly had positive experiences of Interprofessional Collaborative Practice, signaling it is appropriate for chronic condition management in primary care. The patient role in managing their chronic condition was closely linked to their experience. Future studies should investigate how the patient role impacts the experience of patients, carers, and health professionals in this context. Systematic review registration PROSPERO: CRD42020156536.

Download Full-text

A Study on the Analysis of Spatial Typology of Sharing Space

A Journal of Brand Design Association of Korea ◽

10.18852/bdak.2016.14.4.199 ◽

2016 ◽

Vol 14 (4) ◽

pp. 199-218

Author(s):

신은별 ◽

Jinmin Rhie

Keyword(s):

Sharing Space

Download Full-text

Sharing Space Experiences through Augmented Reality as An Alternative Educational Game to Introduce Historic Buildings in Semarang Old Town

10.2991/assehr.k.211228.036 ◽

2022 ◽

Author(s):

Apsari Retno Wiratmi ◽

Intan Rizky Mutiaz

Keyword(s):

Augmented Reality ◽

Educational Game ◽

Historic Buildings ◽

Sharing Space

Download Full-text

Effects of long-term closed environment on human saliva microbiota and salivary cytokines

10.1101/2020.10.12.336750 ◽

2020 ◽

Author(s):

Yinzhen Zhu ◽

Zikai Hao ◽

Yuming Fu ◽

Jianlou Yang ◽

Chen Dong ◽

...

Keyword(s):

Human Saliva ◽

Mucosal Barrier ◽

Future Research ◽

Controlled Environment ◽

List Type ◽

Tnf Α ◽

Normal Environment ◽

The Difference ◽

Sharing Space ◽

The Impact

AbstractCompared with the normal environment, the microbiota in controlled closed cabins such as space capsules, Lunar/Mars bases have changed. To ensure the health of crewmembers, it’s necessary to understand the effects of these changes on human symbiotic microorganisms and immunity. In this study, the experimental platform “Lunar Palace 1” with a similar closed and controlled environment was used to research the effects of changed microbial exposure on human saliva microbiota and salivary cytokines. This paper studied on four crewmembers who participated in the third phase of the “Lunar Palace 365” experiment, analyzing the dynamic changes of saliva microbiota and salivary cytokines, and further studying the correlation between salivary cytokines and highly abundant genera. According to our data, the crewmembers’ saliva microbiota and salivary cytokines fluctuated smoothly throughout the whole experiment. Although a part of microbes increased or decreased some times, they recovered quickly after leaving the controlled environment. The level of IL-6, IL-10 and TNF-α in crewmembers’ saliva decreased from normal environment to the controlled environment, showing reduced levels of oral inflammatory response in crewmembers. In addition, although there were significant individual differences in crewmembers’ saliva microbiota, sharing living space reduced the difference. Furthermore, the level of TNF-α showed a consistent positive correlation with the abundance of Actinomyces and Rothia in the controlled environment, indicating healthy individuals’ oral mucosal barrier may be sensitive to changes in saliva microbiota. According to the result, semi-sterile environments in controlled closed cabins didn’t cause persistent changes in human saliva microbiota and oral immunity. Besides, it provides a new idea for future research on the impact of the controlled environment on crewmembers health, and provides guidance for studying the effect of semi-sterile environments on human immunity based on saliva microbiota.Key pointsSaliva microbes kept stable for individual but got convergent when sharing space;The level of salivary cytokines reduced after entering the controlled environment;There were complex correlations between salivary cytokines and saliva microbes;The crewmembers adapt well to the controlled environment.

Download Full-text