Regulation of Carcinogens: Are Animal Tests a Sound Foundation?

2018 ◽  
pp. 251-280
Author(s):  
Aaron Wildavsky
2011 ◽  
Vol 21 (1) ◽  
pp. 5-14
Author(s):  
Christy L. Ludlow

The premise of this article is that increased understanding of the brain bases for normal speech and voice behavior will provide a sound foundation for developing therapeutic approaches to establish or re-establish these functions. The neural substrates involved in speech/voice behaviors, the types of muscle patterning for speech and voice, the brain networks involved and their regulation, and how they can be externally modulated for improving function will be addressed.


2020 ◽  
Vol 3 (3) ◽  
pp. 37-50
Author(s):  
Muhammad Suleman Nasir

Society means a group of people who are living together. People need society from birth to death. Without a collective life, man's deeds, intentions, and habits have no value. Islamic society is the name of a balanced and moderate life in which human intellect, customs, and social etiquette are determined in the light of divine revelation. This system is so comprehensive and all-encompassing that it covers all aspects and activities of life. Islam is a comprehensive, universal, complete code of conduct, and an ideal way of life It not only recognizes the collectiveness of human interaction. Rather, it helps in the development of the community and gives it natural principles that strengthen the community and provides good foundations for it and eliminates the factors that spoil it or make it limited and useless. The Principles of a successful social life in Islamic society seem to reflect the Islamic code of conduct and human nature. Islam is the only religion that advocates goodness and guarantees well-being. Islam gives us self-sacrifice, generosity, trust and honesty, service to the people, justice and fairness, forgiveness and kindness, good society and economy, good deeds, mutual unity, harmony, and brotherhood. Only by practicing the pure thoughts, beliefs, and unparalleled ideas of the religion of Islam, can a person live a prosperous life and he can feel real peace and lasting contentment in the moments of his life. A descriptive and analytical research methodology will be used in this study. It is concluded that for a prosperous social life it is necessary to abide by the injunction of Islamic principles, which provides a sound foundation for a successful social life here in the world and hereafter.


Author(s):  
Ricardo Ortiz Ortega ◽  
Alonso Vilches Flores ◽  
Marco Aurelio Rodríguez Monroy ◽  
Patricia Bonilla Lemus

Studies accomplished in freshwater demonstrate the importance of identify the presence of<br />protozoa like free living amoebae (FLA). In particular, the genera Acanthamoeba is associated with<br />severe infections in man, as the Granulomatous Amebic Encephalitis (GAE). The most important<br />factor for the development of these organisms is the high temperature of the water body. The<br />region of the Huasteca Potosina in Mexico, with a tropical climate and great aquatic resorts, like<br />rivers, waterfalls and pools of thermal waters, that allows the development of amoebae. In this<br />study we evaluated the presence of amoebas in the most visited places on the Huasteca Potosina.<br />Samples of a liter were taken in nine sites during the rainy and dry season. 54 strains of amoebas<br />were identify, 46 belong to the genera Acanthamoeba, resulting 30 of them pathogenic in the<br />animal tests. The pathogenic isolated amoebas were present in the most attended resorts by the<br />people in the waterfalls or pools of the places sampling. Temperature turned out to be the most<br />important factor for the presence of amoebae.


1997 ◽  
Vol 25 (3) ◽  
pp. 343-345
Author(s):  
Ethel Thurston

The Multicenter Evaluation of In Vitro Cytotoxicity programme is most important to animal protection, since it has validated 64 in vitro tests using advanced human data for 50 chemicals as the “gold standard”. Therefore, it has been able to compare animal cell tests, human cell tests and whole-animal tests fairly with unbiased scientific evidence. Added bonuses have included the identification and development of missing in vitro information (“missing tests”), publication of time-related lethal blood concentrations for all 50 chemicals, and some preliminary plans to resolve the 50,000 untested (or poorly tested) chemicals in the chemical mountain.


2021 ◽  
pp. 1-16
Author(s):  
Bjørn Hofmann

Abstract Although efficiency is a core concept in health economics, its impact on health care practice still is modest. Despite an increased pressure on resource allocation, a widespread use of low-value care is identified. Nonetheless, disinvestments are rare. Why is this so? This is the key question of this paper: why are disinvestments not more prevalent and improving the efficiency of the health care system, given their sound foundation in health economics, their morally important rationale, the significant evidence for a long list of low-value care and available alternatives? Although several external barriers to disinvestments have been identified, this paper looks inside us for mental mechanisms that hamper rational assessment, implementation, use and disinvestment of health technologies. Critically identifying and assessing internal inclinations, such as cognitive biases, affective biases and imperatives, is the first step toward a more rational handling of health technologies. In order to provide accountable and efficient care we must engage in the quest against the figments of our minds; to disinvest in low-value care in order to provide high-value health care.


Author(s):  
R.S Lampitt ◽  
E.P Achterberg ◽  
T.R Anderson ◽  
J.A Hughes ◽  
M.D Iglesias-Rodriguez ◽  
...  

The oceans sequester carbon from the atmosphere partly as a result of biological productivity. Over much of the ocean surface, this productivity is limited by essential nutrients and we discuss whether it is likely that sequestration can be enhanced by supplying limiting nutrients. Various methods of supply have been suggested and we discuss the efficacy of each and the potential side effects that may develop as a result. Our conclusion is that these methods have the potential to enhance sequestration but that the current level of knowledge from the observations and modelling carried out to date does not provide a sound foundation on which to make clear predictions or recommendations. For ocean fertilization to become a viable option to sequester CO 2 , we need more extensive and targeted fieldwork and better mathematical models of ocean biogeochemical processes. Models are needed both to interpret field observations and to make reliable predictions about the side effects of large-scale fertilization. They would also be an essential tool with which to verify that sequestration has effectively taken place. There is considerable urgency to address climate change mitigation and this demands that new fieldwork plans are developed rapidly. In contrast to previous experiments, these must focus on the specific objective which is to assess the possibilities of CO 2 sequestration through fertilization.


1994 ◽  
Vol 8 (5) ◽  
pp. 945-950 ◽  
Author(s):  
M.I. Luster ◽  
C. Portier ◽  
D.G. Pait ◽  
D.R. Germolec
Keyword(s):  

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