CLINICOPATHOLOGICAL EVALUATION OF SINONASAL REGION LESIONS: A SINGLE CENTER EXPERIENCE

2021 ◽  
Vol 6 (15) ◽  
pp. 31-38
Author(s):  
irem bigat ◽  
Pınar Celepli ◽  
Salih Celepli

Benign and malignant lesions of the sinonasal area are frequently seen in the clinic. The aim of this study was to evaluate the pathological and clinical features of patients diagnosed with sinonasal lesions in the Department of Pathology of the University of Health Sciences Ankara Training and Research Hospital between 2016 and 2019. Evaluation was made of benign and malignant sinonasal lesions reported in the Department of Pathology of the University of Health Sciences Ankara Training and Research Hospital between 2016 and 2019. The data including age, gender, diagnosis, localization and clinical information of patients diagnosed with benign and malignant sinonasal lesions were obtained retrospectively from the hospital information system and patient files. The data sets created were then evaluated statistically and the results were discussed in the light of the relevant literature. From the data sets obtained from the patient data, it was observed that the number of benign lesions in the sinonasal region (91%) was higher than malignant lesions (9%). Patients with sinonasal masses were predominantly in the 41-50 years age group, with a male to female ratio of 2:1. Rhinorrhea and nasal obstruction were determined to be the most common symptoms at presentation. The anatomic localization of the lesions sent to the pathology department was classified by the clinician, and reported as 84.5% nasal cavity, 3.5% nasal septum, 1.6% nasal concha, 2.2% nasal vestibule, and 8.2% paranasal sinus. According to the pathological diagnoses of these cases, sinonasal polyps with benign characteristics were found at the rate of 82.6%, and inverted papilloma with the potential for malignancy and recurrence at 8.5%. Sinonasal lesions are often benign but malignant potential should not be ignored. It should be kept in mind that benign and malignant lesions of this region may show similar symptoms and indications in clinical evaluation. Therefore, endoscopic and pathological evaluation is important for lesions detected in the sinonasal region.

1995 ◽  
Vol 34 (01/02) ◽  
pp. 75-78 ◽  
Author(s):  
R. D. Appel ◽  
O. Golaz ◽  
Ch. Pasquali ◽  
J.-C. Sanchez ◽  
A. Bairoch ◽  
...  

Abstract:The sharing of knowledge worldwide using hypermedia facilities and fast communication protocols (i.e., Mosaic and World Wide Web) provides a growth capacity with tremendous versatility and efficacy. The example of ExPASy, a molecular biology server developed at the University Hospital of Geneva, is striking. ExPASy provides hypermedia facilities to browse through several up-to-date biological and medical databases around the world and to link information from protein maps to genome information and diseases. Its extensive access is open through World Wide Web. Its concept could be extended to patient data including texts, laboratory data, relevant literature findings, sounds, images and movies. A new hypermedia culture is spreading very rapidly where the international fast transmission of documents is the central element. It is part of the emerging new “information society”.


2014 ◽  
Vol 1 (2) ◽  
pp. 206
Author(s):  
Haluk TANRIVERDİ ◽  
Mucize SARIHAN

The main purpose of this study is to examine the effects of health workers’ levels of work commitment on the levels of depression and burnout.  Having this purpose in mind, a questionnaire consisting of personal information form, work commitment scale, burnout scale and depression scale was conducted with 266 health workers of İstanbul Kartal Training and Research Hospital in May 2013. Data obtained from questionnaires were analyzed by SPSS 17,0 statistical software. Correlation analysis was utilized in order to determine the relationships among work commitment, burnout and depression levels of health workers whereas regression analysis was utilized in order to determine the effects of health workers’ levels of work commitment on the levels of depression and burnout. According to the results, it has been found that there are statistically relevant relationships among work commitment, burnout and depression levels of health workers. It has been concluded that the more health workers’ levels of work commitment increase, their levels of depression and burnout decrease.


2020 ◽  
Vol 10 (01) ◽  
pp. e233-e239
Author(s):  
Sabide Duygu Uygun ◽  
Fatma Hülya Çakmak ◽  
Merve Canlı ◽  
Rahime Duygu Temeltürk ◽  
Ayşegül Efe ◽  
...  

AbstractThis study aimed to examine demographic and clinical variables, psychiatric comorbidities, the prevalence of psychotropic drug use, relationships between drug use, demographic and clinical variables, and predictors of drug use in children with autism spectrum disorder (ASD) admitted to a training and research hospital outpatient clinic. Four hundred and eleven children with ASD admitted to the Department of Child and Adolescent Psychiatry, Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, between October 1, 2019 and December 31, 2019, were retrospectively reviewed. Demographic and clinical variables, psychiatric comorbidities, and characteristics of drug use for the cases were recorded. Psychotropic drug use was found in 34.3% (n = 141) of the cases. Our results revealed male sex and psychiatric comorbidity as predictors of psychotropic drug use. Antipsychotics were the most prescribed drugs, and the most common psychiatric comorbidity was conduct disorder. Also, children with ASD who had been toilet-trained, and could express sentences but were illiterate, were using psychotropic drugs more often than others. Future multicentered, large clinic-based studies from training and research hospitals should focus on trends of treatment in psychiatric comorbidities accompanying ASD, and constitute a systematic approach for the psychopharmacological treatment of these cases.


2001 ◽  
Vol 16 (3) ◽  
pp. 99-101
Author(s):  
Cari Spence

The purpose of this study was to identify prevalence rates of medical problems among flautists. The Flute Health Survey (FHS), a questionnaire with items regarding musculoskeletal and nonmusculoskeletal problems, was distributed at the 1999 National Flute Association annual meeting (n = 40). This questionnaire was pilot tested at the 1999 Texas Flute Festival, which is hosted by the Texas Flute Society. The University of North Texas has posted on the Internet a similar questionnaire regarding the medical problems of all musicians. Responses from the University of North Texas Musician Health Survey (UNT-MHS) were filtered to include only those respondents who denoted flute as their primary instruments (n = 328). Data sets from both surveys were then processed using comparative statistics. Findings show that there was no significant difference between the demographics of the two populations. Only one musculoskeletal site, the left hand, was found to be statistically significant between the two groups. Four nonmusculoskeletal items, depression, earache, headache, and sleep disturbances, were found to be different between the two groups. The overall findings of this comparison show that there are many medical problems facing the flute playing community. Further investigation and observations of this population are necessary.


Author(s):  
Matthew E Ehrlich ◽  
Heather L Turner ◽  
Lillian J Currie ◽  
Max Wintermark ◽  
Bradford B Worrall ◽  
...  

Objective: To evaluate the safety and utility of CTA acquisition during initial acute stroke evaluation. We hypothesized CTA would not increase risk of renal injury or delay therapy. Design/Methods: We performed a pilot study of CTA acquisition in the acute stroke evaluation at the University of Virginia Medical Center in the first three quarters of 2014. We extracted data from Acute Stroke Team Leader consultations with additional chart review. We collected door-to-CT read times, door-to-needle times, baseline creatinine (Cr) values on presentation, and Cr values 24-48 hours after stroke alert evaluation. Differences in means of these variables were compared between those receiving CTA versus non-contrasted head CT (NCHCT) only. Additionally, we captured CTA results immediately relevant to treatment decisions. Results: Of 289 patients, 157 had CTA completed while 132 had only NCHCT. In the CTA group, 18 patients (11.5%) were treated with IV tissue plasminogen activator (tPA) compared to 11 (8.3%) in the NCHCT group, with no significant difference between groups (p=0.377). There was no difference between mean door-to-CT-read times between the NCHCT (43.07 minutes) and CTA (41.46 minutes) groups (p=0.70). Likewise, there was no significant difference in mean door-to-needle times between the NCHCT (81.36 minutes) and CTA (68.11 minutes) groups (p=0.577). There was a difference between mean Cr values on presentation (1.39mg/dL NCHCT, 1.06mg/dL CTA; p=0.004), but there was no difference between the groups at 24-48 hours (p=0.059) and no difference between the mean change in Cr values (p=0.489). No patients developed a new requirement for hemodialysis. CTA imaging revealed 14 patients with vascular anomalies, and 53 patients with severe stenosis or occlusion of a major cervical or intracranial vessel. One patient in the CTA group and none in the NCHCT group had intravascular intervention. Conclusions: Overall, CTA during acute stroke evaluations were safe and may offer clinical utility, without delaying evaluation or therapy delivery. Additional cost of acute CTA acquisition is negligible given it replaces MRA typically performed later, following admission, as standard vessel imaging. Further prospective study is required.


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