Diagnosis of the Syndrome of Excessive Bacterial Growth of the Small Intestine in Patients with Bauhinia Insufficiency and After its Surgical Correction (First Results)

2020 ◽  
pp. 1-6
Author(s):  
Vladimir Leonidovich Martynov ◽  
◽  
Natalia Vladimirovna Kazarina ◽  
Keyword(s):  
Small Intestine ◽  
Bacterial Growth ◽  
Ileocecal Valve ◽  
Normal Function ◽  
Main Group ◽  
Surgical Correction ◽  
Control Group ◽  
Distal Small Intestine ◽  
First Results ◽  
Respiratory Test

Objective: To determine the syndrome of excessive bacterial growth in the small intestine (SIBO) in patients with insufficiency of the bauhinia valve (NBZ) and after its surgical correction. Methods of examination: Patients of the studied groups were examined using direct and indirect methods of diagnosis of SIBO. Bacteriological examination of ileal aspirate and other surgical material was performed. All patients underwent a hydrogen respiratory test with a load of lactulose and performed a qualitative reaction of urine to indican. Characteristics of the material: 50 patients were examined, of which 30 were included in the main group, who underwent surgical correction of NBZ - Bauginoplasty; 20 patients are included in the control group in which the ileocecal valve is consistent. Patients of the main group were examined before surgery and on the 7th and 45th day after Bauhinoplasty. Main results: All patients of the main group had SIBS of varying severity, in 80% of patients SIBS was localized in the distal small intestine. Patients with normal function of ileocecal valve syndrome of excessive bacterial growth did not suffer. Intraoperatively, 76% of patients showed signs of mesenteric mesentery of the small intestine, and the fact of bacterial translocation in SIBO was also confirmed. After 7 days after surgical correction of the Bauhinia valve, the normalization of peak and background excretion of hydrogen was observed in 37% of patients. For 45 days in all patients the hydrogen curve corresponded to the norm. Conclusions: the deficiency of the bauhinia valve is obligately accompanied by the syndrome of excessive bacterial growth in the small intestine, surgical correction is an effective method for correcting the syndrome of excessive bacterial growth in patients with NBD.

scholarly journals SMALL INTESTINE BACTERIAL OVERGROWTH IN PATIENTS WITH FAILURE OF THE VALVE BAUHINIAS AND AFTER ITS SURGICAL TREATMENTS (THE FIRST RESULTS)

2015 ◽  
Vol 14 (2) ◽  
pp. 12-19
Author(s):  
V. L. Martvnov ◽  
A. K. Khairdinov
Keyword(s):  
Small Intestine ◽  
Bacterial Overgrowth ◽  
Ileocecal Valve ◽  
Normal Function ◽  
Main Group ◽  
Surgical Correction ◽  
Overgrowth Syndrome ◽  
First Results ◽  
Respiratory Test ◽  
Surgical Treatments

Оbjective: diagnosis of the a small intestine of bacterial overgrowth syndrome (SIBO) in patients with the failure of the bauginias valve (FBV) and after its surgical correction.Material and methods. Patients of the studied groups were examined by means of direct and indirect methods of diagnostics of SIBO. Bacteriological research of an aspirate of aillium gut and other operational material was conducted. To all patients the hydrogen respiratory test was carried out and highquality reaction of urine to an indican was carried out. 50 patients are examined, from them 30 are inclu ded in the main group by which surgical correction of FBV – a bauginoplastik is made; 20 patients are included in group of control at which the illeocecal valve is well-founded. Patients of the main group were examined before operation and for the 7th and 45th days after a bauginoplastik.Results. At all patients of the main group SIBO of varying severity is defined, at 80% of patients of SIBO was localized in distal part of the small intestine. Patients with normal function of the ileocecal valve a SIBO did not suffer. At 76% of patients revealed signs of a mezadenitisof a small intestine, the fact of a bacterial translocation at SIBO is confirmed. In 7 days after surgical correction of the bauginiasvalve normalization of a peak and background excretion of hydrogen was noted at 37% of patients. For the 45th days at all patients the hydrogen digram met standard.Conclusions. The failure of the bauginiasvalveis obligatory followed by a small intestine of bacterial overgrowth syndrome, surgical correction is an effective method of correction of a SIBO at patients with FBV.

scholarly journals Procedure of complex braided wrapping of ascending aorta in her poststenotic dilation while doing correction of aortal stenosis

2020 ◽  
Vol 87 (9-10) ◽  
pp. 18-21
Author(s):  
V. V. Popov ◽  
A. A. Bolshak
Keyword(s):  
Ascending Aorta ◽  
Main Group ◽  
Surgical Correction ◽  
Control Group ◽  
Valve Prosthesis ◽  
Original Procedure ◽  
Aortal Valve ◽  
The Moment ◽  
Aorta Diameter

Objective. To study clinical possibilities of original procedure of the ascending aorta braid-like bandage for her poststenotic dilation while performance of the aortal stenosis surgical correction. Materials and methods. To the main Group 196 patients were included those, who were operated on for prevailing aortal stenosis, conjoined with poststenotic dilation of ascending aorta. In accordance to the echocardiographic investigation data the ascending aorta diameter preoperatively have constituted (47.7 ± 1.7) mm. In all the patients the aortal valve prosthesis was performed together with complex braided wrapping of ascending aorta. Into the control group 121 patients were included, in whom Bentall intervention was accomplished with vascular prosthesis of ascending aorta. Results. Hospital lethality in the main group have constituted 0.5%. Diameter of ascending aorta in the moment of hospital discharge have constituted (39.1 ± 1.5) mm, and in late follow-up period - (40.3 ± 1.1) mm. Conclusion. Basing on clinical experience gained, it is expedient to recommend the original procedure of braided wrapping of ascending aorta in presence of her poststenotic dilation while performing surgical correction of prevailing aortal stenosis.

Use of Cellular Technologу at Surgical Correction of Congenital Lower Limb Length Discrepancy in Children

2011 ◽  
Vol 18 (1) ◽  
pp. 3-9
Author(s):  
S P Mironov ◽  
Nikolay Petrovich Omel'yanenko ◽  
O V Kozhevnikov ◽  
V K Il'ina ◽  
A V Ivanov ◽  
...  
Keyword(s):  
Bone Marrow Cells ◽  
Limb Length Discrepancy ◽  
Main Group ◽  
Control Group ◽  
Duration Of Treatment ◽  
Length Discrepancy ◽  
First Results ◽  
Cellular Technology ◽  
Stimulation Of

First results of application of cultivated autologous stromal bone marrow cells for the stimulation of distraction bone regenerates' reparative regeneration in 8 patients aged from 3.7 to 16 years with congenital lower extremity length discrepancy (main group) are presented. In 24 children with similar pathology aged from 2.5 to 14 years (control group) no cellular technology was used. In the main group duration of treatment reduces to 4.5-6.5 months versus 7.5- 11 months in the control one. That enabled to avoid potential complications related to the long-term fixation of the extremity in the distraction apparatus.

Urine indican and hydrogen respiratory test as methods of screaning diagnostics of excessive bacterial growth syndrome in a small intestine

2017 ◽  
pp. 117-121
Author(s):  
V.L. Martynov ◽  
A.G. Semenov ◽  
A.A. Tulupov ◽  
A.A. Chesnokov ◽  
V.A. Kurilov ◽  
...  
Keyword(s):  
Small Intestine ◽  
Bacterial Growth ◽  
Respiratory Test

Peritoneopericardial Diaphragmatic Hernia: A Retrospective Study of 31 Cats and Eight Dogs

2010 ◽  
Vol 46 (6) ◽  
pp. 398-404 ◽  
Author(s):  
Angela C. Banz ◽  
Sharon D. Gottfried
Keyword(s):  
Small Intestine ◽  
Retrospective Study ◽  
Postoperative Complications ◽  
Diaphragmatic Hernia ◽  
Surgical Repair ◽  
Normal Function ◽  
Surgical Correction ◽  
Peritoneopericardial Diaphragmatic Hernia

The records of 31 cats and eight dogs undergoing surgical correction of peritoneopericardial diaphragmatic hernia (PPDH) from 2000 through 2007 were reviewed. Weimaraners and long-haired cats of varying breeds, particularly Maine Coon cats, appear to be at higher risk of PPDH. Presenting complaints were most commonly related to the respiratory and gastrointestinal tracts in both dogs and cats, although respiratory signs were more prevalent in cats, and gastrointestinal signs were more common in dogs. The most common herniated organs were liver, gallbladder, and small intestine. Mortality associated with surgical repair of PPDH in cats and dogs was low in the first 2 weeks postoperatively, and prognosis for return to normal function was excellent. Peri-and postoperative complications were typically minor and self-limiting.

scholarly journals Chronic duodenal stasis and the state of cavity intestinal microbiota

2020 ◽  
pp. 4-10
Author(s):  
Ya. M. Vakhrushev ◽  
M. S. Busygina ◽  
A. P. Lukashevich
Keyword(s):  
Small Intestine ◽  
Bacterial Growth ◽  
The State ◽  
Short Term ◽  
Digestive Tube ◽  
Postprandial Period ◽  
Exhaled Air ◽  
Respiratory Test ◽  
Comprehensive Study

Objective: to study the motor-evacuation function of the gastrointestinal tract in chronic duodenal stasis and the conjugation of their disorders with excessive bacterial growth.Materials and methods. Thirty patients with chronic duodenostasis (DS) aged 37.1 ± 13.8 years were examined. Anamnestic and physical data, results of X-ray and endoscopic examinations, intracavitarymanometry were used in the verification of DS. The determination of excess bacterial growth (IDB) in the small intestine was carried out by analyzing the results of the hydrogen respiratory test (VDT). The assessment of the motor function of the stomach and duodenum was carried out using the gastroenteromanometer GEM-01 “Gastroskan-GEM”. For conducting short-term pH-measurement, the Gastroskan-5M device was used.Results. All patients with DS presented dyspeptic complaints, revealed asthenic syndrome. In the postprandial period, impaired propulsive motility in all sections of the digestive tube was also expressed, which proves a 1.5-fold decrease in fasting urea, jejunum and ileum by 1.5 times in both phases of the study (p& <0.001). In patients with DS, IDB was detected in 22 (78.6%) cases. Among all examined patients in 19 (67.9%) patients, IDB was associated with increased bacterial activity in the small intestine. Colon dysbiosis was detected in 3 (10.7%) patients (χ2 = 7.093, p = 0.008). A correlation analysis between the hydrogen content in exhaled air and the rhythmic coefficient of the large intestine showed a reliable strong feedback (r& = 0.65, p = 0.015).Conclusion. A comprehensive study of the motor-evacuation function of the digestive system and the state of enteric microbiocenosis expands the possibilities of pathogenetically substantiated therapy for diseases of the organs of the gastroduodenobiliary pancreatic zone.

scholarly journals The value of mucosal small intestine microbiota in digestion and absorption disorders in metabolic syndrome

2019 ◽  
Vol 91 (11) ◽  
pp. 32-37
Author(s):  
M V Lyapina ◽  
Ya M Vakhrushev
Keyword(s):  
Metabolic Syndrome ◽  
Small Intestine ◽  
Bacterial Growth ◽  
Gas Chromatography Mass Spectrometry ◽  
Control Group ◽  
Quantitative Composition ◽  
Exercise Tests ◽  
Absorption Function ◽  
Small Intestinal ◽  
The Relationship

Aim. To evaluate the qualitative and quantitative composition of the parietal microbiota of the small intestine (SI) and its significance in the disturbance of the digestive and absorption functions of the small intestine in metabolic syndrome (MS). Materials and methods. 67 patients with metabolic syndrome were examined. In addition to clinical data, a comprehensive study of the digestive and absorption function of SI was carried out using exercise tests with carbohydrates. The compositional characteristics of mucosal SI microbiota in MS patients were determined by gas chromatography mass spectrometry. The relationship of enteric disorders with changes in small intestinal microbiocenosis was assessed by correlation analysis. Results. The majority (82.9%) of patients with metabolic syndrome showed clinical local and general signs of small intestinal lesions. Violations of all stages of the hydrolysis - resorption process were revealed against the background of changes in the quantitative and qualitative composition of the parietal microbiota of the small intestine. In patients with MS, excessive bacterial growth is observed in the small intestine mainly due to conditionally pathogenic microbiota strains, and, in comparison with the control group, there is a significant increase in the growth of aerobes, microscopic fungi and viruses. The relationship between the severity of excess bacterial growth and impaired digestion and absorption in the small intestine in MS. Conclusion. The results of our research suggest that the identified changes in the functional state of SI in combination with a violation of mucosal enteral microbiocenosis are an important link in the complex pathogenesis of the MS.

scholarly journals THE FIRST RESULTS OF LAPAROSCOPIC INTRAPERITONEAL ALLOPLASTY OF UMBILICAL AND POSTOPERATIVE VENTRAL HERNIAS WITH CLOSURE OF THE HERNIAL DEFECT USING 3D LAPAROSCOPY

2019 ◽  
pp. 56-58
Author(s):  
A. V. Malinovsky ◽  
S. Y. Badion
Keyword(s):  
Main Group ◽  
Control Group ◽  
Average Volume ◽  
3D Laparoscopy ◽  
First Results ◽  
Ventral Hernias

Abstract. The aim of the study was to analyze the first results of laparoscopic alloplasty of the umbilical and postoperative ventral hernias with suturing the hernial defect using 3D laparoscopy. During the period from September 2018 to April 2019, we performed 12 intraperitoneal alloplastic umbilical and postoperative hernias of medium and large sizes. The main group consisted of 7 patients who underwent intraperitoneal alloplasty with closure of the hernial defect and sac. 3D laparoscopy was used in some patients, (Epic HD system, Richard Wolf). The control group consisted of 5 patients who underwent intraperitoneal alloplasty without suturing the hernial defect and sac. Seromes in the main group were in 3 cases, the average volume was 2 ml (from 0.5 to 3 ml), in the control group seromes were also in 3 cases, the average volume was 2.8 ml (from 1 to 5.5 ml). The immediate results, tracked from 1 to 6 months, showed no recurrence in both groups.

scholarly journals Endotoxemia in metabolic syndrome and some mechanisms of its development

2020 ◽  
pp. 11-17
Author(s):  
M. V. Lyapina ◽  
A. P. Lukashevich ◽  
Ya. M. Vakhrushev
Keyword(s):  
Metabolic Syndrome ◽  
Small Intestine ◽  
Electrical Activity ◽  
Bacterial Growth ◽  
Empty Stomach ◽  
Control Group ◽  
Intestinal Damage ◽  
Endotoxin Level ◽  
Postprandial Period ◽  
The Metabolic Syndrome

The aim. Assessment of the relationship between the occurrence of endotoxemia and impaired resorption function of the small intestine, arrhythmia of the motility of the stomach and intestines, and excessive bacterial growth in the metabolic syndrome (MS).Materials and methods. 62 patients with MS were examined. The average age was 48.62+3.75 years. The motor function of the gastrointestinal tract was studied using peripheral electrogastroenterocolography. To assess the absorption processes in the small intestine, stress tests with glucose and d-xylose were used. Blood endotoxin level, quantitative and& qualitative composition of parietal microbiota of small intestine were determined using an Agilent gas chromatograph with mass-selective and flame-ionization detectors (Agilent Technologies, USA).Results. 82.9% of the examined patients with MS showed clinical signs of intestinal damage. The electrical activity of& the& small intestine departments in the postprandial period was low in 70% of patients. The electrical activity of& the& colon on an empty stomach was not changed, and after a food load was reduced. Discoordination of motility is observed between small intestine and the colon, aggravated after food stimulation. A significant decrease in the rhythm of contractions is observed at the frequencies of the jejunum, ileum, and colon both on an empty stomach and in the postprandial period, which indicates a weakening of propulsive bowel contractions in patients with MS. In patients with MS, an increase in& the& absorption of glucose and d-xylose was revealed in comparison with the group of healthy individuals. In patients with MS, excessive bacterial growth in small intestine is observed mainly due to conditionally pathogenic microbiota strains. According to the results of the study of blood endotoxin level in patients with MS, a significant increase was revealed in comparison with the control group. Correlation analysis showed a moderate negative relationship between the level of endotoxin and electrical activity of small intestine, between the level of endotoxin and the ratio of the ratio of& the& colon to the ileum. A moderate positive relationship was established between the degree of endotoxemia increase and glucose absorption in small intestine.Conclusion. A study of the level of endotoxin and indicators of excessive bacterial growth, motor evacuation and resorption functions of small intestine revealed important pathogenetic patterns regarding the contributing role of the latter in& the development of endotoxemia in patients with MS.

scholarly journals Assessment of the Functional Status of the Small Intestine in Patients with Non-Alcoholic Fatty Liver Disease

2020 ◽  
Vol 10 (6) ◽  
pp. 468-474
Author(s):  
Ya. M. Vakhrushev ◽  
A. P. Lukashevich
Keyword(s):  
Small Intestine ◽  
Liver Disease ◽  
Fatty Liver ◽  
Bacterial Growth ◽  
Fatty Liver Disease ◽  
Resistance Index ◽  
Control Group ◽  
Alcoholic Fatty Liver ◽  
Insulin Resistance Index ◽  
Alcoholic Fatty Liver Disease

The aim. A comprehensive study of the functional state of the small intestine and the study of the relationship of its disorders with the development of non-alcoholic fatty liver disease.Materials and methods. 86 patients with non-alcoholic fatty liver disease at the stage of steatosis and steatohepatitis were examined according to the results of ultrasound examination of the liver using the SONIX OP apparatus (Canada) and the FibroMax test of BioPredictiv company (Paris, France). Patients underwent a blood glucose test using an Huma Star 600 analyzer (Germany) and insulin using an enzyme-linked immunosorbent assay. The HOMA-IR insulin resistance index was calculated. In order to determine abnormal digestive disorders in the small intestine, a stress test was performed with soluble starch, membrane digestion with sucrose, absorption with glucose. IDBs were evaluated using a hydrogen breath test on a LactofN2 apparatus from the AMA firm (St. Petersburg). To assess colonic microflora, stool was sown for dysbiosis.Results. According to clinical data, in patients with non-alcoholic fatty liver disease, damage to the small intestine occurs in a non-manifest form. However, in the study of the functional state of the small intestine in patients, a significant decrease in cavity and membrane digestion, increased absorption are detected. In patients with non-alcoholic fatty liver disease, an increase in blood insulin was observed compared with the control group (16,64±0,78 μIU/ml versus 10,46±0,56 μI/ml, p=0,000002). The HOMA-IR insulin resistance index was also increased in patients compared with the control group (2,84±0,11 versus 2,05±0,07, p=0,00003). Excessive bacterial growth was diagnosed in 62 (72%) of patients with non-alcoholic fatty liver disease, while with liver steatosis — in 33 (55%), with steatohepatitis 1 degree of activity — in 11 (61,1%), with steatohepatitis 2 degrees — in 6 (66,7%), with steatohepatitis 3 degrees — in 2 (100%) of patients. According to the results of stool stool, dysbiosis was detected in 56 (65,1%) of patients with non-alcoholic fatty liver disease. A correlation analysis revealed negative relationships between the severity of excessive bacterial growth and digestive digestion, between the severity of excessive bacterial growth and membrane digestion, and a positive relationship between the severity of excessive bacterial growth and absorption.Conclusion. Non-alcoholic fatty liver disease is accompanied by disorders of the digestive and resorptive functions of the small intestine, and the development of dysbiosis. These disorders are often subclinical in nature and can be identified and evaluated after special studies.

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