Frequency of Vitamin D Deficiency and its association with serum PTH levels in End stage renal disease patients.

2020 ◽  
pp. 1-13
Author(s):  
Sidra Sattar ◽  
Farzana Adnan ◽  
Shahid Waheed
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Serum Alkaline Phosphatase ◽  
Chi Square ◽  
Vitamin D Levels ◽  
Chi Square Test ◽  
Serum Pth ◽  
Stage Renal Disease ◽  
End Stage

Abstract Objective: To assess the frequency of Vitamin D Deficiency and its association with serum Parathormone (PTH) levels in End stage renal disease patients in our tertiary setup. Methods: This cross sectional study was conducted in the Department of Nephrology, Liaquat National Hospital from January to December 2016 and comprised of End stage renal disease on maintenance hemodialysis. Sample size of 113 at 8% prevalence was calculated inflated to 150. Participants were selected through purposive sampling technique. Numerical variables were expressed as mean +/- SD (standard deviation) while categorical variables were expressed as frequency and percentages. To determine association between Vitamin D and serum Parathormone (PTH) levels chi-square test was applied. Association of serum alkaline phosphatase levels with both Vitamin D levels and PTH levels was analyzed using chi-square test. SPSS 20 was used for data analysis. P-value <0.05 was taken as significant. Results: Of the 150 participants, 33 were drop outs, 63(53.8%) were males and 54(46.2%) were females. The overall mean age was 52.47+15.21. Of all, hypertension as a comorbidity was present in 64(54.7%), Diabetes mellitus was present in 8(6.8%) and cardiovascular disease in 7(6%). Among the biochemical markers, mean serum vitamin D levels were 18.6+13.6ng/ml, mean Serum PTH levels were 253.8+227.2pg/ml, mean serum alkaline phosphatase levels were 143.7+125.4µg/L, mean serum phosphorus levels were 4.81+3.46mg/dl and mean serum calcium levels were 21.41+114.4mg/dl. Among the study participants, 67(57.3%) were found to be Vitamin D deficient. Continuous...  

scholarly journals The relation between vitamin D status and anemia in patients with end stage renal disease on regular hemodialysis

2021 ◽  
Vol 7 (1) ◽  
pp. e15-e15
Author(s):  
Essam Nour el Din Afifi ◽  
Ahmed Mohamed Tawfik ◽  
Essam Eldin Rashed Saeed Abdulkhalek ◽  
Lina Essam Khedr
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Serum Calcium ◽  
End Stage Renal Disease ◽  
Iron Status ◽  
Vitamin D Status ◽  
Vitamin D Levels ◽  
Stage Renal Disease ◽  
End Stage ◽  
Regular Hemodialysis

Introduction: Anemia is a common complication in end-stage renal disease (ESRD) patients on regular hemodialysis (HD). There has been a lot of interest recently in the non-classical effects of 25(OH) vitamin D (calcidiol), including its association with erythropoiesis and anemia pathogenesis. Objectives: To study the relation between anemia and vitamin D status in patients on regular HD Results: This study is a cross-sectional study that included 90 patients on regular HD. Vitamin D status was classified into deficient (<20 ng/ mL), insufficient (20-30 ng/mL) and sufficient (>30 ng/mL). The level of vitamin D measured in the patients ranged between 3.5 to 66 ng/mL with median of 16.35 ng/mL. There were statistically significant positive correlations between vitamin D levels and the level of hemoglobin (P<0.001), serum calcium levels (P<0.001) and serum PO4 levels (P=0.023). Higher hemoglobin levels were statistically related to both higher vitamin D values (P<0.001) and higher serum calcium concentration P<0.001). Meanwhile, a significant negative correlation was found between hemoglobin levels and serum PTH values (P<0.001). Conclusion: There was a significant association between the status of vitamin D and the level of hemoglobin in dialysis population who were studied, independent from iron status. other associations with hemoglobin levels included PTH level and calcium.

scholarly journals 25-Hydroxy Vitamin D Levels in Hemodialysis-Requiring End-Stage Renal Disease Patients

2008 ◽  
Vol 37 (10) ◽  
pp. 388-390 ◽  
Author(s):  
Guillermo Javier Rosa Diez ◽  
Juliana Fassi ◽  
Soledad Crucelequi ◽  
Hector Rivera Nuñez ◽  
Matias Trillini ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Vitamin D Levels ◽  
25 Hydroxy Vitamin D ◽  
Stage Renal Disease ◽  
End Stage

Role of vitamin D in oxidative stress modulation in end‐stage renal disease patients: A double‐blind randomized clinical trial

2020 ◽  
Vol 24 (3) ◽  
pp. 367-373
Author(s):  
Leila Malekmakan ◽  
Zeinab Karimi ◽  
Afshin Mansourian ◽  
Maryam Pakfetrat ◽  
Jamshid Roozbeh ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Clinical Trial ◽  
Vitamin D ◽  
Renal Disease ◽  
Randomized Clinical Trial ◽  
End Stage Renal Disease ◽  
Double Blind ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Apa I polymorphism in the vitamin D receptor gene may affect the parathyroid response in Japanese with end-stage renal disease

1998 ◽  
Vol 53 (2) ◽  
pp. 454-458 ◽  
Author(s):  
Keitaro Yokoyama ◽  
Takashi Shigematsu ◽  
Toshihiko Tsukada ◽  
Yousuke Ogura ◽  
Fumi Takemoto ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Vitamin D Receptor ◽  
End Stage Renal Disease ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Vitamin D receptor genetic variants among patients with end-stage renal disease

Renal Failure ◽  
2010 ◽  
Vol 32 (8) ◽  
pp. 969-977 ◽  
Author(s):  
Gaurav Tripathi ◽  
Richa Sharma ◽  
Raj K. Sharma ◽  
Sushil Kumar Gupta ◽  
Satya Narayan Sankhwar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Vitamin D Receptor ◽  
Genetic Variants ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals CONTINUOUS AMBULATORY PERITONEAL DIALYSIS USING STRAIGHT TYPE VS COILED TYPE TENCKHOFF CATHETER IN END-STAGE RENAL DISEASE PATIENTS AT SARDJITO HOSPITAL

2011 ◽  
Vol 18 (1) ◽  
Author(s):  
Eka Yudha Rahman ◽  
Sungsang Rochadi ◽  
Trisula Utomo
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
End Stage Renal Disease ◽  
Chi Square ◽  
Catheter Migration ◽  
Tenckhoff Catheter ◽  
Significant Difference ◽  
Stage Renal Disease ◽  
End Stage

Objective: The purpose of this study was to compare straight type versus coiled type Tenckhoff catheter for continuous ambulatory peritoneal dialysis (CAPD) in end stage renal disease. Material & method: A prospective cohort study enrolled end-stage renal disease patients undergoing CAPD for renal replacement therapy in Urology and Nephrology Department, Sardjito Hospital from January to December 2007. Identity and type of Tenckhoff catheter were recorded. Patients were grouped into two groups who used straight type catheter and coiled type catheter for CAPD, then observed for post-operative complication. Statistical analysis was done using SPSS 14.0 with chi-square test. Results: There were 27 patients included in this study. The cause of end-stage renal disease was mostly DM and hypertension. The most common complication after  operation  was catheter  obstruction  (9 patients). Another complication was intraabdominal bleeding (1 patient), and catheter migration (1 patient). In patients with straight catheter (20 patients), there were 8 patients (40%) with complication. In patients with coiled catheter (7 patients), there were 3 patients (42%) with complication. There was no significant difference in complications between straight and coiled catheter groups (p = 0,895). Conclusion: The result of this study revealed that no significant difference in complication between straight and coiled catheter for CAPD in end-stage renal disease patients

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