A case report of synchronous bilateral tonsillar carcinoma associated with human papilloma virus

2020 ◽  
pp. 1-9
Author(s):  
Shunji Tamagawa ◽  
Mehmet Gunduz ◽  
Keisuke Enomoto ◽  
Esra Gunduz ◽  
Kenji Warigaya ◽  
...  
Keyword(s):  
Case Report ◽  
Cervical Lymphadenopathy ◽  
Neck Surgery ◽  
Pcr Analysis ◽  
Papilloma Virus ◽  
Tonsillar Carcinoma ◽  
Hpv Dna ◽  
Dna Pattern ◽  
Medical University

Abstract The case of a 69-year-old man with bilateral synchronous tonsillar carcinoma is reported. The patient complained of nasal closure, strange voice, and discomfort in his pharynx when he was admitted to the Department of Otolaryngology Head and Neck Surgery at Wakayama Medical University, Wakayama, Japan, in March 2017. The palatine tonsils were enlarged and the surface was irregular. Left cervical lymphadenopathy was also evident. Histological examination from both tonsils was performed and bilateral tonsillar squamous cell carcinoma was diagnosed. PCR analysis showed the same HPV-DNA pattern from bilateral tonsils. Concurrent chemoradiotherapy was performed. Total 70 Gy of irradiation (2Gy/day×35 day) was applied to bilateral tonsillar tumours and upper neck. Follow up was conducted every three months and the patient was free of recurrence for three years. Patient’s informed consent was taken to publish the case report. Keywords: bilateral synchronous tonsillar carcinoma, HPV, tonsil Continuous...

scholarly journals Case Report: Rosai-Dorfman Disease Involving Sellar Region in a Pediatric Patient: A Case Report and Systematic Review of Literature

2020 ◽  
Vol 7 ◽  
Author(s):  
Yi Zhang ◽  
Jie Liu ◽  
Jianyu Zhu ◽  
Xiang Zhou ◽  
Kun Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Pediatric Patient ◽  
Cervical Lymphadenopathy ◽  
Sellar Region ◽  
Rosai Dorfman Disease ◽  
The Individual ◽  
Mass Lesions ◽  
Endocrine Abnormality

Rosai-Dorfman disease (RDD) is an extremely rare histiocytic disorder characterized by cervical lymphadenopathy, while the involvement of sellar region is less observed. Here we report a pediatric patient who was initially suspected as sellar germinoma but later identified as RDD. We also conducted a systematic review about RDD involving sellar region. A total of only 14 cases were included and analyzed in our study in terms of clinical presentation, endocrine abnormality, radiological features, pathology, treatment, and follow up. The most common neurological manifestations of sellar RDD is diabetes insipidus and visual changes. Two typical kinds of MRI manifestations were presented in sellar RDD; one is like meningioma-like mass lesions, another showing infiltrative pattern that demonstrates hyperintense areas on T2WI. Currently, the treatment of RDD is tailored to the individual clinical circumstances. For sellar RDD, surgical treatment can be considered to completely remove or debulk the tumor.

Initial Treatment of CD20+ Lymphocyte Predominant Hodgkin Lymphoma with Chemotherapy and the Monoclonal Antibody Rituximab-Mabthera Is Effective and Well Tolerated - Case Report.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 4696-4696
Author(s):  
Sonja G. Genadieva-Stavrik ◽  
Lubomir Ivkovski ◽  
Aleksandra Pivkova ◽  
Lidija Cevreska
Keyword(s):  
Case Report ◽  
Complete Remission ◽  
Patient Population ◽  
Mediastinal Mass ◽  
Early Stage ◽  
Cervical Lymphadenopathy ◽  
Malignant Cells ◽  
Limited Information ◽  
Patients Experience

Abstract Patients with lymphocyte-predominant Hodgkin disease (LPHD) often present at an early stage with slow disease progression. Although 96% of LPHD patients experience a complete remission (CR) upon first line treatment, many relapses occur. CD20+ is strongly expressed by malignant cells in LPHD, but so far there is limited information regarding the efficacy of rituximab in this patient population. We report 46-year-old woman who presented in 2004 with left cervical lymphadenopathy and weight loss. Case report: Biopsy confirmed a diagnosis of LPHD(stage IIB disease), immunohistochemistry revealed that >30% of malignant cells were CD20+, and a bulky mediastinal mass was observed by computer tomography (CT). Blood counts, erythrocyte sedimentation rate, albumin and lactate dehydrogenate were normal. The patient was treated with rituximab and ABVD (doxorubicin 25mg/m2, bleomycin 10mg/m2, vinbalstine 6mg/m2, dacarbazine 375mg/m2, six cycles). Rituximab was administered (375mg/m2) one day before chemotherapy (50mg/h for one hour and gradually escalated to a maximum of 400mg/h). Treatment was well tolerated and there were no complications. The patient was assessed immediately following treatment and every three months for the following year, by physical examination, CT, bone marrow biopsy and routine analyses. A detectable tumor mass was no observed by CT for the follow up of 2 years, the patient remains in complete remission. Conclusion: Our case report suggests that Rituximab is both safe and effective in patients with CD20+ LPHD. Further studies with Rituximab are warranted in this patient population.

scholarly journals Foramen Magnum Meningioma: A Rare Case Report

2014 ◽  
Vol 13 (3) ◽  
pp. 69-73
Author(s):  
Haradhan Deb Nath ◽  
Kanak Kanti Barua ◽  
Shahnewaj Bari ◽  
Hafizul Amin
Keyword(s):  
Case Report ◽  
Vertebral Artery ◽  
Rare Case ◽  
Cranial Nerves ◽  
Foramen Magnum ◽  
Rare Case Report ◽  
Proper Training ◽  
Lower Cranial Nerves ◽  
Medical University

Background: Foramen magnum meningiomas are challenging tumors, requiring special considerations because of the vicinity of the medulla oblongata, the lower cranial nerves, and the vertebral artery. After detailing the relevant anatomy of the foramen magnum area, we will explain our classification system based on the compartment of development, the dural insertion, and the relation to the vertebral artery. Method: A 35 years age lady with foramen magnum meningioma was operated at the Department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University 6 months back. A case report was taken before surgery and 6 month follow up was done after operation. Conclusion: As foramen magnum meningioma is very difficult to approach, with the help of microscope with proper training. We can remove completely without any deficit.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i3.21031 

scholarly journals Atopic Dermatitis: a Case Report of a 3-year-old Food Allergy Child Sensitive to Multiple Allergens

2021 ◽  
Author(s):  
Meiyi Wang ◽  
Xueqing Liang ◽  
Baoqing Sun ◽  
Huimin Huang
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Case Report ◽  
Milk Powder ◽  
Food Allergies ◽  
Test Results ◽  
Formula Milk ◽  
Infant Formula Milk ◽  
Medical University

Abstract Background: It was estimated that about 10% of the population suffer from food allergy. Atopic dermatitis is often associated with food allergy. In this case report, we presented a child with atopic dermatitis who was sensitive to multiple food and inhaled allergens.Case report: A 3-year-old boy was admitted to the First Affiliated Hospital of Guangzhou Medical University due to skin allergy caused by drinking semi-hydrolyzed infant formula milk powder. Allergen test results showed that the boy was sensitive to multiple food and inhaled allergens. we conducted the follow-up interview by phone to completed the questionnaire.Conclusion: Atopic dermatitis children with multiple food allergies must pay attention to diet adjustment to prevent or delay the development of the disease.

Unusual location for Castleman's disease

2008 ◽  
Vol 123 (1) ◽  
Author(s):  
H G Rao ◽  
I Street ◽  
R Capper
Keyword(s):  
Case Report ◽  
Castleman’S Disease ◽  
Cervical Lymphadenopathy ◽  
Castleman's Disease ◽  
Complete Excision ◽  
Unusual Location ◽  
Posterior Triangle ◽  
Left Neck ◽  
Life Threatening

AbstractObjective:We present the first reported case of persistent, posterior triangle lymphadenopathy in a child, caused by Castleman's disease.Case report:A seven-year-old boy presented with a painless swelling in the posterior triangle of his left neck, with no compression of the surrounding structures. A histological diagnosis of Castleman's disease was made. Eventual treatment was by complete excision. At six-month follow up, there were no signs of recurrence.Conclusion:The causes of persistent cervical lymphadenopathy in children are many. Most are not significant, but some are life-threatening. Castleman's disease should be considered as a possible diagnosis in persistent childhood lymphadenopathy.

scholarly journals Atopic Dermatitis: A Case Report of a 3-Year-Old Food Allergy Child Sensitive to Multiple Allergens

2020 ◽  
Author(s):  
Meiyi Wang ◽  
Xueqing Liang ◽  
Baoqing Sun ◽  
Huimin Huang
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Case Report ◽  
Milk Powder ◽  
Food Allergies ◽  
Test Results ◽  
Formula Milk ◽  
Infant Formula Milk ◽  
Medical University

Abstract Background: It was estimated that about 10% of the population suffer from food allergy. Atopic dermatitis is often associated with food allergy. In this case report, we presented a child with atopic dermatitis who was sensitive to multiple food and inhaled allergens. Case report: A 3-year-old boy was admitted to the First Affiliated Hospital of Guangzhou Medical University due to skin allergy caused by drinking semi-hydrolyzed infant formula milk powder. Allergen test results showed that the boy was sensitive to multiple food and inhaled allergens. we conducted the follow-up interview by phone to completed the questionnaire. Conclusion: Atopic dermatitis children with multiple food allergies must pay attention to diet adjustment to prevent or delay the development of the disease.

scholarly journals Management of metastatic neck node in thyroid carcinoma

1970 ◽  
Vol 16 (2) ◽  
pp. 80-85
Author(s):  
Md Shazibur Rashid ◽  
Mohammad Ashequr Rahman Bhuiyan ◽  
Mohammad Shafiqul Islam ◽  
Belayat Hossain Siddiquee
Keyword(s):  
Thyroid Carcinoma ◽  
Neck Dissection ◽  
Cervical Lymphadenopathy ◽  
Locoregional Control ◽  
Neck Node ◽  
Node Metastasis ◽  
Neck Node Metastasis ◽  
Study Results ◽  
Medical University

Objective: To see the results of neck dissection in thyroid carcinoma with metastatic cervical lymphadenopathy. Methods: This study was carried out in the Department of Otolaryngology at Bangabandhu Sheikh Mujib Medical University, Dhaka, for the period of two years from July 2006 to June 2008. Carcinoma thyroid patients with neck node were included in this study. Results: Mean age of the patients were 43.5 years. Mean follow up period was 15 months. In cases where radical or modified radical neck dissections were done no recurrence were found. Recurrences were found in 13.33% cases where selective neck dissections were done. Overall recurrence in anatomical neck dissection is 7.40% only. But in berry picking recurrence rate is 66.66% cases. So in berry picking locoregional control of disease is less satisfactory than anatomical neck dissection. Conclusion: In anatomical neck dissection locoregional control of disease is significantly more satisfactory than berry picking. Key words: Thyroid carcinoma; Papillary; Follicular; Medullary; Neck node metastasis. DOI: 10.3329/bjo.v16i2.6832Bangladesh J Otorhinolaryngol 2010; 16(2): 80-85

scholarly journals Kikuchi-Fujimoto Disease in a Filipino Boy: A Case Report

2019 ◽  
Vol 34 (2) ◽  
pp. 35-38
Author(s):  
Jenina Rachel Escalderon ◽  
Angelo Monroy
Keyword(s):  
Case Report ◽  
Private Hospital ◽  
Cervical Lymphadenopathy ◽  
Excision Biopsy ◽  
Cervical Lymph Nodes ◽  
History Of ◽  
Necrotizing Lymphadenitis ◽  
Supportive Management ◽  
Multiple Diagnosis

Objective: To report a case of a 12-year-old boy with Necrotizing Lymphadenitis (Kikuchi-Fujimoto disease) presenting as lymphadenitis secondary to multiple diagnosis.   Methods: Design : Case Report Setting: Tertiary Private Hospital Patient: One   Results: A 12-year-old boy consulted for two-month history of cervical lymphadenopathy with the underlying cause remaining unclear despite multiple consults, diagnosis and medical treatment. Lymphoma was considered and excision biopsy with further investigations confirmed a diagnosis of Kikuchi-Fujimoto disease. Supportive management was given with no recurrence of symptoms noted on 18 months of follow up.    Conclusion:  Kikuchi-Fujimoto disease in this case was a diagnosis of exclusion. Even with a proper history and physical examination, experts in otolaryngology can be misled to manage this case as malignant. Awareness of the disease and appropriate examinations including immunohistochemistry are important for a timely diagnosis and proper intervention.   Keywords: lympadenitis; Kikuchi-Fujimoto disease; lymphoma; cervical lymph nodes

scholarly journals Multiple Keratoacanthomas after a Recent Tattoo: A Case Report

2021 ◽  
pp. 23-27
Author(s):  
Fouad Mitri ◽  
Wolfgang Hartschuh ◽  
Ferdinand Toberer
Keyword(s):  
Human Papillomavirus ◽  
Case Report ◽  
Safety Margin ◽  
Skin Lesions ◽  
Pcr Analysis ◽  
History Of ◽  
The Right ◽  
Red And Black Pigments

We report on a 39-year-old man who presented with seven skin lesions on the right thigh 3 weeks after receiving a large tattoo which included red and black pigments. Initially, the lesions grew fast, later their growth stabilized. Histopathology showed well-circumscribed symmetric tumors with a central keratin-filled crater along with further trademarks of a keratoacanthoma. The patient had previously had multiple tattoos with no history of similar lesions. PCR analysis of one of the lesions revealed the presence of human papillomavirus 6. All lesions were excised with a safety margin. A 3-month follow-up revealed no further lesions.

Intensive Stuttering Therapy With Telepractice Follow-up: A Case Study

2011 ◽  
Vol 21 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Farzan Irani ◽  
Rodney Gabel
Keyword(s):  
Case Report ◽  
Therapeutic Intervention ◽  
Intensive Therapy ◽  
Positive Outcome ◽  
Eclectic Approach

This case report describes the positive outcome of a therapeutic intervention that integrated an intensive, residential component with follow-up telepractice for a 21 year old male who stutters. This therapy utilized an eclectic approach to intensive therapy in conjunction with a 12-month follow-up via video telepractice. The results indicated that the client benefited from the program as demonstrated by a reduction in percent stuttered syllables, a reduction in stuttering severity, and a change in attitudes and feelings related to stuttering and speaking.

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