scholarly journals The impact of vitamin D level on serum lipids in type 2 diabetes mellitus

2021 ◽  
Vol 2 (04) ◽  
pp. 230-236
Author(s):  
Zainab Subber ◽  
Hashim Hashim ◽  
Ghassan Al-Shamma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Serum Lipids ◽  
Fasting Blood Glucose ◽  
The Body ◽  
Diabetic Group ◽  
The Impact

Background: Vitamin D is considered an important regulator of many metabolic processes in the body. Its deficiency was reported to associate with many pathological conditions, with contradicting reports on its role in dyslipidemia. Objectives: To evaluate the role of vitamin D (total and/or free) in improving dyslipidemia of type 2 diabetes mellitus (T2DM). Methods: Sixty-four patients with T2DM, and 73 apparently healthy normal subjects were enrolled in the study from March to October 2020. Their fasting blood glucose, glycated hemoglobin, HbA1c, and serum lipids (cholesterol, its fractions and triglycerides) were measured in addition to total and free vitamin D. Results: There was a significant negative correlation between total vitamin D and each of cholesterol and LDL-C in the diabetic group. The correlations between serum vitamin D and all other lipid parameters (HDL-C, VLDL-C and triglycerides) were non-significant in the diabetic group, while in the control groups none of serum lipids showed significant correlations with vitamin D. Conclusions: The significant negative association of vitamin D with total cholesterol and LDLC in the diabetics reveals the important action of vitamin D in reducing the atherogenic indices, and consequent reduction in the rate of atherosclerosis and cardiovascular disease or stroke.

scholarly journals The association between Gastric Bacterial Infection and Low Level of Vitamin D among Patients with type 2 Diabetes Mellitus

2021 ◽  
Vol 2 (01) ◽  
pp. 38-46
Author(s):  
Sarah T. Al-Mofarji ◽  
Haider .K. Hussien ◽  
Nadira Salman Mohamed ◽  
Sundus Fadhil Hantoosh ◽  
Mohammed Khudier Abass ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Fasting Blood Glucose ◽  
Diabetic Group ◽  
Diabetic Patients ◽  
Vitamin D Levels ◽  
H Pylori

Objectives: The present research aimed to find an association between infection by  Helicobacter pylori and vitamin D deficiency in type 2 diabetes mellitus among Iraqi individuals attending Al-Yarmouk Teaching Hospital. Methods: According to fasting blood glucose,  the samples were divided into a non-diabetic group with ten diabetic individuals and a diabetic group with thirty individuals. Results: The anti-H. Pylori (IgG) levels were 86.77± 58.62 NTU/µL in diabetic patients compared with 10.12 ± 7.40 NTU/µL in non- diabetic group. Vitamin D levels were decreased significantly in infected patients compared to non-infected subjects. Conclusion: The H pylori-infected patients have recorded the lowest level of vitamin D than non-infected individuals.

scholarly journals The impact of serum lipids on risk for microangiopathy in patients with type 2 diabetes mellitus

2012 ◽  
Vol 11 (1) ◽  
pp. 109 ◽  
Author(s):  
Peter P Toth ◽  
Robert J Simko ◽  
Swetha Palli ◽  
Dawn Koselleck ◽  
Ralph A Quimbo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Serum Lipids ◽  
The Impact

Association of Vitamin D Levels and type 2 Diabetes Mellitus in Asian Indians is Independent of Obesity

2018 ◽  
Vol 126 (09) ◽  
pp. 553-558 ◽  
Author(s):  
A. Gupta ◽  
M. Aslam ◽  
S. Rathi ◽  
B. Mishra ◽  
S. Bhardwaj ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Asian Indian ◽  
Asian Indians ◽  
Diabetic Group ◽  
Vitamin D Levels ◽  
Significant Difference

Abstract Background A large proportion of subjects with type 2 diabetes mellitus (T2DM) in India are non-obese. Asian-Indian subjects with diabetes have been shown to have low vitamin D levels. Whether low vitamin D levels and T2DM in Asian-Indians is attributable to the associated obesity as in caucasians is unclear. Hence we studied the association of vitamin D levels and T2DM in Asian-Indians with or without obesity. Methods Total of 213 subjects were recruited in four groups, group 1-Non-obese diabetic, group 2-Non-obese non-diabetic, group 3-Obese diabetic and group 4-Obese non-diabetic. Subjects recruited under various groups were matched for age and sex. Anthropometry, skin-fold thickness, fasting and postprandial plasma glucose, HbA1c, fasting insulin, lipids and vitamin D levels were measured in all study subjects and were compared between the groups. Results Mean age of study population was 41.23±7.43 years. Mean BMI in groups 1,2,3 and 4 was 21.34±1.41, 20.53±2.27, 27.72±2.94 and 27.62±3.37 kg/m2 respectively. Overall 64.3% study subjects had vitamin D deficiency and 27.7% had insufficient vitamin D levels. Significantly lower vitamin D levels were found in diabetic groups 1 and 3 compared to non-diabetic groups 2 and 4. No significant difference was observed in vitamin D levels between groups 1 and 3. Similarly, no significant difference was observed in vitamin D levels between groups 2 and 4. Vitamin D levels did not show any significant correlation with BMI, waist or body fat. Conclusion Vitamin D levels do not appear to be related to obesity in diabetic as well non-diabetic Asian-Indian individuals.

scholarly journals Relationship Of Stress Levels And Diet With Blood Sugar Levels In Patients Of Type 2 Diabetes Mellitus

2020 ◽  
Vol 9 (1) ◽  
pp. 241-247
Author(s):  
Ninik Ambar Sari ◽  
Ceria Nurhayati ◽  
Sri Anik Rustini
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Fasting Blood Glucose ◽  
Sampling Technique ◽  
The Body ◽  
Cross Sectional ◽  
Sugar Levels

Diabetes mellitus type 2 is a condition in which the body tissue doesn’t respond to the action of insulin. Type 2 DM can cause complications if it doesn’t managed properly, good DM management behavior for patients needs to be done by maintaining a healthy diet and stress will increase blood sugar levels. This study uses analytic cross sectional design. The sampling technique in this study was purposive sampling of 60 respondents. Data processing using the SPSS program with the Spearman Rho test. Results: a correlation between stress level and fasting blood glucose level of type 2 diabetes mellitus patients with a correlation value of 0.544, which is located between 0.4 - <0.6, is in the medium category. While the statistical test for diet obtained a significant number or ρ = 0.002 then Ho is rejected, H1 is accepted.

Study and evaluation the impact of vitamin D receptor variants on the risk of type 2 diabetes mellitus in Han Chinese

2016 ◽  
Vol 9 (3) ◽  
pp. 275-284 ◽  
Author(s):  
Fei Yu ◽  
ChongJian Wang ◽  
Ling Wang ◽  
HongLin Jiang ◽  
Yue Ba ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Vitamin D Receptor ◽  
Han Chinese ◽  
The Impact

Estimation of vitamin D receptor gene polymorphism in Type 2 Diabetes Mellitus patients in Erbil city

2021 ◽  
Vol 67 (3) ◽  
pp. 76-84
Author(s):  
Kalthum Asaaf Maulood
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Vitamin D Receptor ◽  
Diabetic Group ◽  
Control Group

Type 2 diabetes mellitus (T2DM) is a global problem. Recent studies confirmed the association of genes and different single nucleotide polymorphisms with T2DM occurrence and progress. This study was aimed to estimate the vitamin D receptor (VDR) gene polymorphism in Type 2 Diabetes Mellitus patients in Erbil city. The results showed that the Body mass index (BMI), Systolic blood pressure and Diastolic blood pressure were significantly higher in the diabetic group compared to the control group (P<0.05). In addition, the percent of Glycated hemoglobin (HbA1c), Fasting blood glucose (FBG), and Homeostatic model assessment for insulin resistance (HOMA-IR) were significantly higher in the diabetic group compared to the control group (P<0.05). Among different parameters of lipid profile, only Low-density lipoprotein (LDL) was significantly higher in the diabetic group compared to the control group. It was found that FBG value was significantly higher in patients with GA and AA genotypes of BsmI compared with healthy controls. Patients with the GA genotype of BsmI had a higher value of triglyceride compared to healthy individuals. Patients with all ApaI genotypes had higher FBS values than controls. There were not observed any signi?cant associations among the BsmI and ApaI polymorphisms and the risk of T2DM. In conclusion, no evidence was found for the association between two VDR polymorphisms and T2DM patients in Erbil city.

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